Compounds > temozolomide
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temozolomide and sulfasalazine

temozolomide has been researched along with sulfasalazine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, L; Li, X; Liu, L; Liu, Y; Xue, Y; Yu, B1
Buchfelder, M; Dörfler, A; Engelhorn, T; Eyüpoglu, IY; Fan, Z; Ghoochani, A; Klucken, J; Minakaki, G; Rauh, M; Savaskan, N; Sehm, T1
Castilho, RF; De Melo, DR; Facchini, G; Ignarro, RS; Lopes-Cendes, I; Rogerio, F; Vieira, AS1
Aboody, KS; Cassady, K; Cherryholmes, GA; Marinov, GK; Polewski, MD; Reveron-Thornton, RF1
Castilho, RF; de Melo, DR; Facchini, G; Ferreira, CV; Ignarro, RS; Pelizzaro-Rocha, KJ; Rogerio, F1

Reviews

1 review(s) available for temozolomide and sulfasalazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for temozolomide and sulfasalazine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function.
    Oncology reports, 2015, Volume: 33, Issue:3

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biological Transport; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Dacarbazine; Drug Resistance, Neoplasm; Enzyme Activation; Glioblastoma; Glutathione; Humans; NF-E2-Related Factor 2; Piperazines; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Sulfasalazine; Temozolomide

2015
Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain Edema; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dacarbazine; Dose-Response Relationship, Drug; Drug Synergism; Glioma; Humans; Magnetic Resonance Imaging; Rats, Wistar; Sulfasalazine; Temozolomide; Tumor Microenvironment

2016
Sulfasalazine intensifies temozolomide cytotoxicity in human glioblastoma cells.
    Molecular and cellular biochemistry, 2016, Volume: 418, Issue:1-2

    Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytotoxins; Dacarbazine; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Sulfasalazine; Temozolomide

2016
Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:12

    Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; Drug Resistance, Neoplasm; Drug Synergism; Gene Knockdown Techniques; Glioblastoma; Glutathione; Humans; Mice; Neoplasm Transplantation; Reactive Oxygen Species; Sulfasalazine; Temozolomide

2016
Characteristics of sulfasalazine-induced cytotoxicity in C6 rat glioma cells.
    Neuroscience letters, 2017, 01-18, Volume: 638

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dacarbazine; Glioma; Glutathione; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats; Sulfasalazine; Temozolomide

2017