Compounds > temozolomide
Page last updated: 2024-08-16

temozolomide and simvastatin

temozolomide has been researched along with simvastatin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aghaei, M; Akbari, M; Albokashy, M; Alizadeh, J; Butterfield, Y; Cole, LK; Eftekharpour, E; Ghavami, S; Hatch, GM; Hombach-Klonisch, S; Islam, MI; Kardami, E; Klonisch, T; Koleini, N; Marzban, H; Samiei, E; Shojaei, S; Thliveris, J; Vosoughi, AR; Xu, F1
Dastghaib, S; Ghavami, S; Mokarram, P; Mostafavi-Pour, Z; Patterson, JB; Samali, A; Sharma, P; Shojaei, S1

Reviews

1 review(s) available for temozolomide and simvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for temozolomide and simvastatin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes.
    The FEBS journal, 2020, Volume: 287, Issue:5

    Topics: Animals; Autophagosomes; Cell Death; Cell Line, Tumor; Female; Glioblastoma; Humans; Lysosomes; Macrolides; Mice; Simvastatin; Temozolomide; Xenograft Model Antitumor Assays

2020
Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.
    Cells, 2020, 10-22, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Glioblastoma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phosphorylation; Signal Transduction; Simvastatin; Temozolomide; Unfolded Protein Response

2020