Page last updated: 2024-08-16

temozolomide and quercetin

temozolomide has been researched along with quercetin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's12 (80.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Huang, H; Lian, XY; Liang, Y; Ye, X; Yu, S; Zhang, Z1
Burd, R; Limesand, KH; Mendoza, EE; Mitchell, GC; Radhakrishnan, VM; Sittadjody, S; Thangasamy, T1
Jakubowicz-Gil, J; Langner, E; Piersiak, T; Rzeski, W; Wertel, I1
Jakubowicz-Gil, J; Langner, E; Rzeski, W1
Bądziul, D; Jakubowicz-Gil, J; Langner, E; Rzeski, W; Wertel, I2
Bellyei, S; Boronkai, A; Cseh, A; Hocsak, E; Pozsgai, E; Racz, B; Sumegi, B; Szabo, A1
Lan, Q; Li, RJ; Sang, DP1
Dang, X; Hu, J; Wang, G; Wang, J; Yao, Z1
Bomal, E; Choi, J; Kakkar, A; Maysinger, D; Moquin, A; Na, L1
Armenia, E; Barbarisi, A; Barbarisi, M; De Sena, G; Iaffaioli, RV; Quagliariello, V; Schiavo, L; Tafuto, S1
Aguilar, MI; Crook, T; Del Borgo, MP; Hirmiz, B; Kiriakidi, S; Kolettas, E; Markopoulos, GS; Mavromoustakos, T; Renziehausen, A; Sayyad, N; Syed, N; Tsiailanis, AD; Tzakos, AG; Vrettos, EI; Widdop, RE1
Chen, J; Li, B; Mu, J; Wang, Q; Wang, W; Wu, X; Xu, L; Yin, Z; Yuan, X; Zeng, Z; Zhu, X; Zou, Y1

Other Studies

15 other study(ies) available for temozolomide and quercetin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Bioactive triterpenoid saponins and phenolic compounds against glioma cells.
    Bioorganic & medicinal chemistry letters, 2014, Nov-15, Volume: 24, Issue:22

    Topics: Animals; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioma; Humans; Phenols; Plant Extracts; Rats; Saponins; Structure-Activity Relationship; Triterpenes

2014
Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73.
    BMC cancer, 2010, Jun-11, Volume: 10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Dacarbazine; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Melanins; Melanoma; Mutation; Nuclear Proteins; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Protein Transport; Quercetin; RNA Interference; Temozolomide; Time Factors; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2010
Temozolomide, quercetin and cell death in the MOGGCCM astrocytoma cell line.
    Chemico-biological interactions, 2010, Oct-06, Volume: 188, Issue:1

    Topics: Apoptosis; Astrocytoma; Blotting, Western; Brain Neoplasms; Cell Death; Cell Line, Tumor; Dacarbazine; Fluorescent Antibody Technique, Indirect; Humans; Quercetin; Temozolomide

2010
Kinetic studies of the effects of Temodal and quercetin on astrocytoma cells.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Astrocytoma; Autophagy; Cell Line, Tumor; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Humans; Necrosis; Quercetin; Temozolomide

2011
Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antioxidants; Apoptosis; Brain Neoplasms; Caspase 12; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Cytochromes c; Dacarbazine; Endoplasmic Reticulum Stress; Enzyme Activation; Glioblastoma; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Membrane Potential, Mitochondrial; Mitochondria; Molecular Chaperones; Quercetin; Temozolomide

2013
Quercetin increases the efficacy of glioblastoma treatment compared to standard chemoradiotherapy by the suppression of PI-3-kinase-Akt pathway.
    Nutrition and cancer, 2013, Volume: 65, Issue:7

    Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoradiotherapy; Dacarbazine; Glioblastoma; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Quercetin; Signal Transduction; Temozolomide

2013
Silencing of Hsp27 and Hsp72 in glioma cells as a tool for programmed cell death induction upon temozolomide and quercetin treatment.
    Toxicology and applied pharmacology, 2013, Dec-15, Volume: 273, Issue:3

    Topics: Apoptosis; Astrocytoma; Autophagy; Caspase 12; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; Dacarbazine; Endoplasmic Reticulum Stress; Gene Silencing; Glioblastoma; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Membrane Potential, Mitochondrial; Molecular Chaperones; Quercetin; Temozolomide

2013
Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27.
    Acta pharmacologica Sinica, 2014, Volume: 35, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Dacarbazine; Glioblastoma; HSP27 Heat-Shock Proteins; Humans; Quercetin; Temozolomide

2014
Pharmacokinetics and antitumor efficacy of DSPE-PEG2000 polymeric liposomes loaded with quercetin and temozolomide: Analysis of their effectiveness in enhancing the chemosensitization of drug-resistant glioma cells.
    International journal of molecular medicine, 2016, Volume: 37, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Delivery Systems; Drug Resistance, Neoplasm; Glioma; Humans; Liposomes; Phosphatidylethanolamines; Polyethylene Glycols; Quercetin; Random Allocation; Rats; Rats, Sprague-Dawley; Temozolomide

2016
Telodendrimers for Physical Encapsulation and Covalent Linking of Individual or Combined Therapeutics.
    Molecular pharmaceutics, 2017, 08-07, Volume: 14, Issue:8

    Topics: Acetazolamide; Carbonic Anhydrase IX; Cell Line, Tumor; Cell Survival; Dacarbazine; Dendrimers; Drug Delivery Systems; Glioblastoma; Humans; Lactates; Micelles; Polyesters; Polyethylene Glycols; Quercetin; Spheroids, Cellular; Temozolomide

2017
Novel nanohydrogel of hyaluronic acid loaded with quercetin alone and in combination with temozolomide as new therapeutic tool, CD44 targeted based, of glioblastoma multiforme.
    Journal of cellular physiology, 2018, Volume: 233, Issue:10

    Topics: Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hydrogel, Polyethylene Glycol Dimethacrylate; Interleukin-6; Interleukin-8; Molecular Targeted Therapy; Nanoparticles; Polymers; Quercetin; Temozolomide; Vascular Endothelial Growth Factor A

2018
Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid.
    Free radical biology & medicine, 2020, 11-20, Volume: 160

    Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Losartan; Quercetin; Temozolomide

2020
Quercetin induces MGMT
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 118

    Topics: Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioblastoma; Glioma; Humans; Molecular Docking Simulation; NF-kappa B; Proto-Oncogene Proteins c-akt; Quercetin; Reactive Oxygen Species; Signal Transduction; Temozolomide

2023