Page last updated: 2024-08-16

temozolomide and paclitaxel

temozolomide has been researched along with paclitaxel in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's16 (22.22)29.6817
2010's45 (62.50)24.3611
2020's11 (15.28)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Ekins, S; Williams, AJ; Xu, JJ1
Bakalara, N; Clarion, L; Filippini, D; Hirlemann, MH; Jacquard, C; Lecouvey, M; Loiseau, S; Pirat, JL; Sainte-Catherine, O; Virieux, D; Volle, JN1
Chen, J; Hosni-Ahmed, A; Jones, TS; Li, W; Li, XS; Miller, DD; Patil, R; Patil, SA; Seibel, WL; Wang, J1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Aksenov, AV; Aksenov, NA; Aksenova, IV; Brenner, AJ; Bryan, BA; Cavazos, DA; Correa, J; De Carvalho, A; Frolova, LV; Johnston, RK; Kiss, R; Kornienko, A; Lefranc, F; Magedov, IV; Mathieu, V; Nguyen, G; Pendleton, AL; Reisenauer, MR; Rogelj, S; Rubin, M; Smirnov, AN1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aksenov, AV; Brenner, AJ; Cavazos, DA; Cencic, R; Dasari, R; Evidente, A; Frolova, LV; Henry, S; Kidner, R; Kiss, R; Kornienko, A; Lefranc, F; Ma, X; Magedov, IV; Mathieu, V; Pelletier, J; Pertsemlidis, A; Reisenauer, MR; Rogelj, S; Yu, X1
Liu, Y; Xu, Z; Zhao, SJ1
Chen, HC; Dai, Z; Liu, H; Liu, HY; Liu, YP; Luo, XD; Wang, B; Yan, H; Yang, D; Zhao, LX; Zhao, XD; Zhao, YL; Zhu, PF; Zhu, YY1
Gangjee, A; Hamel, E; Ihnat, MA; Luckett-Chastain, LR; Mooberry, SL; Quadery, TM; Xiang, W1
Kuang, Y; Li, B; Liang, L; Qiao, X; Ye, M; Yi, Y1
Bafaloukos, D; Briassoulis, E; Fountzilas, G; Georgoulias, V; Gogas, H; Kalofonos, Ch; Karabelis, A; Kosmidis, P; Samantas, E; Skarlos, D1
Newton, HB; Santi, M; Stevens, C1
Berman, E; Gallo, JM; Ma, J; Murphy, M; O'Dwyer, PJ; Reed, K1
Cappugi, P; Coronnello, M; Giannotti, B; Mini, E; Pimpinelli, N; Prignano, F1
Li, Y; McClay, EF1
Baker, SD; Donehower, RC; Grochow, LB; Rowinsky, EK; Schellens, JH; Sparreboom, A; Verweij, J1
Baayen, HC; Barkhof, F; Boogerd, W; Castelijns, JA; Elkhuizen, PH; Heimans, JJ; Postma, TJ; Uitdehaag, BM; Vos, MJ1
Azzabi, A; Boddy, AV; Calvert, AH; Calvert, PM; Fishwick, K; Griffin, MJ; Hughes, AN; Kelly, C; Lind, MJ; Maraveyas, A; Plummer, ER; Todd, R1
Fangusaro, J; Finlay, J; Rook, J; Rosser, T1
Greenman, J; Hetherington, JW; Lam, T; Little, S; Maraveyas, A1
Aldape, K; Aoki, H; Bogler, O; Conrad, C; Hess, K; Hollingsworth, EF; Iwado, E; Kobayashi, R; Kondo, S; Kondo, Y; Mills, G; Sawaya, R; Shingu, T; Shinojima, N; Tamada, Y; Yamamoto, A; Yokoyama, T; Zhang, L1
Fichtner, I; Hess-Stumpp, H; Hoffmann, J; Hofmann, B; Klar, U; Lemm, M; Lienau, P; Rotgeri, A1
Patel, R; Shervington, A1
Cubitt, CL; Daud, AI; Homsi, J; Jove, R; Messina, JL; Munster, PN; Sullivan, DM; Yu, H; Zhang, S1
Adema, AD; Honeywell, RJ; Peters, GJ; van der Born, K1
Fruehauf, S; Laufs, S; Maier, P; Spier, I; Veldwijk, MR; Wenz, F; Zeller, WJ1
Cawkwell, L; Little, SJ; Maraveyas, A; Murray, A; Stanley, P1
Lee, FC; Mangalik, A; Movva, S; Parks, V; Rabinowitz, I; Verschraegen, CF1
Anelli, V; Bassi, R; Brioschi, L; Campanella, R; Caroli, M; De Zen, F; Gaini, SM; Giussani, P; Riboni, L; Riccitelli, E; Viani, P1
Ahn, NG; Dallaglio, K; Ellis, LZ; Fujita, M; Gonzalez, R; Lewis, KD; Liu, W; Luo, Y; McCarter, MD; Norris, DA; Robinson, SE; Robinson, WA; Roop, DR; Spritz, RA; Takeda, M1
Boxerman, J; Jeyapalan, S; Raghavan, D; Rogg, J1
Amatruda, TT; Cohen, PA; Geoffroy, FJ; Gross, HM; Jaslowski, AJ; Kaur, JS; Kosel, ML; Kottschade, LA; Markovic, SN; McWilliams, RR; Perez, DG; Suman, VJ1
Allgayer, H; Fruehauf, S; Heckmann, D; Laufs, S; Maier, P; Spier, I; Wenz, F; Zeller, WJ; Zucknick, M1
Chang, J; Cheng, X; Escano, C; Gandhi, A; Kannan, R; Liebes, L; Madden, K; Mendoza, S; Muren, C; Ott, PA; Pavlick, AC; Shao, Y1
Brem, H; Eberhart, CG; Fowers, KD; Hwang, L; Li, KW; Okonma, S; Recinos, VR; Tyler, BM; Vellimana, AK; Zhang, Y1
Boxerman, J; Cielo, D; Constantinou, M; Dipetrillo, T; Donahue, J; Elinzano, H; Evans, D; Goldman, M; Isdale, D; Jeyapalan, S; Kinsella, T; Mantripragada, K; Oyelese, A; Puthawala, Y; Rosati, K; Safran, H; Santaniello, A; Stopa, E1
Cliby, WA; Janco, JM; Markovic, SN; Weaver, AL1
Fan, X; Li, X; Ni, S; Qi, H; Wang, J1
Kim, SS; Kim, SY; Lim, SH; Seong, S1
Koon, HB; Megahed, AI1
Alfano, D; Caputo, E; Cavalcanti, E; Fico, A; Patriarca, EJ; Travali, S; Valentino, A; Vasta, V1
Abhyankar, S; Chang, CL; Donga, P; Munakata, J; Reyes, CM; Schabert, VF; Yim, YM1
Annovazzi, L; Battaglia, L; Caldera, V; Chirio, D; Melcarne, A; Mellai, M; Riganti, C; Schiffer, D1
Annovazzi, L; Biunno, I; Cassoni, P; Cattaneo, M; De Blasio, P; Melcarne, A; Mellai, M; Schiffer, D; Storaci, AM1
Chen, HM; Guan, DG; Liao, SF; Zhao, TZ1
Duan, Y; Gao, P; Shen, M; Sun, Y; Xu, Y1
Duan, Y; Li, Y; Shen, M; Sun, Y; Teng, Y; Wang, Y; Xu, Y1
Castro, MG; Doherty, R; Lowenstein, PR; Wilson, TJ; Zamler, DB1
Blank, C; Cranmer, L; Daud, A; Dummer, R; Ebbinghaus, S; Hamid, O; Hauschild, A; Hille, D; Kang, SP; Loquai, C; Mehnert, JM; O'Day, S; Puzanov, I; Ribas, A; Robert, C; Salama, A; Schachter, J; Schadendorf, D; van den Eertwegh, A; Zhou, W1
Diéras, V; Domchek, SM; Friedlander, M; Garber, JE; Giranda, VL; Han, HS; Isakoff, SJ; Johnson, EF; Kaufman, B; Maag, D; Puhalla, S; Qin, Q; Robson, M; Shepherd, SP; Telli, ML1
Chang, CW; Chen, HH; Chiang, CS; Chiang, WH; Chiu, HC; Huang, WC; Lin, YW; Lu, IL; Tsai, YC1
Chen, J; Ding, L; Duan, Y; Huang, C; Li, R; Shen, M; Sun, Y; Wang, Q; Zhang, X1
Bondarenko, I; Campone, M; Chmielowska, E; Citrin, D; Diéras, V; Domchek, SM; Friedlander, M; Garber, JE; Gradishar, W; Han, HS; Isakoff, SJ; Jager, A; Jakobsen, EH; Kaklamani, V; Kaufman, B; Marcom, PK; Nickner, C; Palácová, M; Puhalla, S; Qian, J; Qin, Q; Ratajczak, CK; Robson, M; Shepherd, SP; Shparyk, Y; Telli, ML1
Tutt, A1
Chmielowski, B; Copley-Merriman, C; Liu, FX; Mauskopf, J; Stevinson, K; Wang, J; Zimovetz, EA1
Nazha, B; Owonikoko, TK1
Specenier, P1
Bozzato, E; Danhier, F; Gallez, B; Ghiassinejad, S; Joudiou, N; Préat, V; Zhao, M1
Schwendeman, SP1
Franken, MG; Gheorghe, M; Haanen, JBAG; Leeneman, B; Uyl-de Groot, CA; van Baal, PHM1
Chai, Z; Li, J; Lu, L; Lu, W; Mao, J; Ran, D; Wu, S; Xie, C; Zhan, C; Zhang, Y; Zhou, J1
Cao, F; Chen, S; Fan, W; Li, D; Ma, W; Qi, H; Shen, L; Song, Z; Wen, X; Wu, Y; Xie, L; Zhang, X1
Bernstein, AM; Deming, TJ; Garrett, MC; Hung, D; Kornblum, HI; O'Shea, TM; Sofroniew, MV; Soto, H; Staarman, B; Wollenberg, AL1
Bazzazzadeh, A; Dizaji, BF; Irani, M; Kianinejad, N; Nouri, A1
Guo, Y; Li, D; Li, Z; Su, W; Wang, Y1
Behrooz, AB; Masarudin, MJ; Masomian, M; Sekawi, Z; Syahir, A; Tajudin, AA; Vazifehmand, R1
Erthal, LCS; Gobbo, OL; Ruiz-Hernandez, E; Shi, Y; Sweeney, KJ1
Alinezhad, A; Behrooz, AB; Davazdahemami, AA; Hamzah, ASA; Homaie, FM; Jamalpour, S; Maddah, SM; Sabah, JT; Vazifehmand, R1

Reviews

7 review(s) available for temozolomide and paclitaxel

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles

2019
Systemic chemotherapy for the treatment of metastatic melanoma.
    Seminars in oncology, 2002, Volume: 29, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carmustine; Cisplatin; Clinical Trials as Topic; Dacarbazine; Humans; Melanoma; Nitrosourea Compounds; Paclitaxel; Tamoxifen; Taxoids; Temozolomide

2002
What is the role of chemotherapy in the treatment of melanoma?
    Current treatment options in oncology, 2014, Volume: 15, Issue:2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Carboplatin; Cisplatin; Clinical Trials as Topic; Dacarbazine; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Immunosuppression Therapy; Immunotherapy; Ipilimumab; Melanoma; Paclitaxel; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Temozolomide; Treatment Outcome

2014
Direct costs associated with adverse events of systemic therapies for advanced melanoma: Systematic literature review.
    Medicine, 2018, Volume: 97, Issue:31

    Topics: Antineoplastic Agents; Dacarbazine; Health Expenditures; Health Resources; Humans; Indoles; Ipilimumab; Melanoma; Paclitaxel; Sulfonamides; Temozolomide; Vemurafenib

2018
Efficacy of nab-paclitaxel in treating metastatic melanoma.
    Expert opinion on pharmacotherapy, 2019, Volume: 20, Issue:5

    Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Dacarbazine; Humans; Melanoma; Paclitaxel; Temozolomide

2019
A systematic literature review and network meta-analysis of effectiveness and safety outcomes in advanced melanoma.
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 123

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azetidines; Benzimidazoles; Cancer Vaccines; Carboplatin; Dacarbazine; gp100 Melanoma Antigen; Humans; Hydrazines; Imidazoles; Interleukin-2; Ipilimumab; Lenalidomide; Melanoma; Network Meta-Analysis; Nitrosourea Compounds; Nivolumab; Organophosphorus Compounds; Oximes; Paclitaxel; Piperidines; Progression-Free Survival; Proportional Hazards Models; Pyridones; Pyrimidinones; Skin Neoplasms; Sorafenib; Survival Rate; Temozolomide; Treatment Outcome; Vemurafenib

2019

Trials

9 trial(s) available for temozolomide and paclitaxel

ArticleYear
Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jan-15, Volume: 20, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Docetaxel; Female; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Neutropenia; Paclitaxel; Skin Neoplasms; Taxoids; Temozolomide; Thrombocytopenia

2002
Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations.
    British journal of cancer, 2005, Mar-28, Volume: 92, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Paclitaxel; Temozolomide

2005
Phase I dose finding study of carboplatin, paclitaxel, and temozolomide in advanced solid tumors.
    Melanoma research, 2011, Volume: 21, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cohort Studies; Dacarbazine; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Paclitaxel; Skin Neoplasms; Small Cell Lung Carcinoma; Temozolomide

2011
A randomized phase 2 study of temozolomide and bevacizumab or nab-paclitaxel, carboplatin, and bevacizumab in patients with unresectable stage IV melanoma : a North Central Cancer Treatment Group study, N0775.
    Cancer, 2013, Feb-01, Volume: 119, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Albumins; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Paclitaxel; Skin Neoplasms; Survival Analysis; Temozolomide; Treatment Outcome; Young Adult

2013
Oblimersen in combination with temozolomide and albumin-bound paclitaxel in patients with advanced melanoma: a phase I trial.
    Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:1

    Topics: Adult; Aged; Albumin-Bound Paclitaxel; Albumins; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Dacarbazine; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Oligonucleotides, Antisense; Paclitaxel; Skin Neoplasms; Temozolomide; Thionucleotides; Treatment Outcome

2013
Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study.
    American journal of clinical oncology, 2014, Volume: 37, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Male; Middle Aged; Paclitaxel; Polyglutamic Acid; Survival Analysis; Temozolomide

2014
Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.
    European journal of cancer (Oxford, England : 1990), 2016, Volume: 67

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dacarbazine; Disease-Free Survival; Female; Health Status; Humans; Male; Melanoma; Middle Aged; Paclitaxel; Patient Reported Outcome Measures; Quality of Life; Skin Neoplasms; Temozolomide; Young Adult

2016
A randomized Phase II study of veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in BRCA1/2 metastatic breast cancer: design and rationale.
    Future oncology (London, England), 2017, Volume: 13, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Carboplatin; Clinical Protocols; Dacarbazine; Drug Monitoring; Female; Humans; Models, Statistical; Paclitaxel; Research Design; Sample Size; Temozolomide

2017
Veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in patients with BRCA1/2 locally recurrent/metastatic breast cancer: randomized phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 01-01, Volume: 29, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Breast Neoplasms, Male; Carboplatin; Female; Genes, BRCA1; Genes, BRCA2; Germ-Line Mutation; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paclitaxel; Placebos; Single-Blind Method; Temozolomide; Young Adult

2018

Other Studies

56 other study(ies) available for temozolomide and paclitaxel

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Oxaphosphinanes: new therapeutic perspectives for glioblastoma.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Survival; Cyclic P-Oxides; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Organophosphonates; Phosphorous Acids; Rats; Stereoisomerism; Structure-Activity Relationship

2012
New substituted 4H-chromenes as anticancer agents.
    Bioorganic & medicinal chemistry letters, 2012, Jul-01, Volume: 22, Issue:13

    Topics: Antineoplastic Agents; Astrocytes; Benzopyrans; Binding Sites; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Drug Screening Assays, Antitumor; Humans; Oligopeptides; Protein Structure, Tertiary; Tubulin; Tubulin Modulators

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Activity of 2-aryl-2-(3-indolyl)acetohydroxamates against drug-resistant cancer cells.
    Journal of medicinal chemistry, 2015, Mar-12, Volume: 58, Issue:5

    Topics: Antineoplastic Agents; Cell Differentiation; Cells, Cultured; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fibroblasts; Humans; Hydroxamic Acids; Indoles; Neoplasms; Neoplastic Stem Cells; Structure-Activity Relationship

2015
5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells.
    European journal of medicinal chemistry, 2016, Sep-14, Volume: 120

    Topics: Amaryllidaceae; Amaryllidaceae Alkaloids; Antineoplastic Agents; Drug Resistance, Neoplasm; Humans; Plant Extracts; Tumor Cells, Cultured

2016
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antineoplastic Agents; Apoptosis; Biological Products; Brain Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioblastoma; Goosecoid Protein; Humans; Molecular Structure; Saponins; Structure-Activity Relationship; Tumor Cells, Cultured

2021
The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity.
    Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cyclopentanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Glioma; Humans; Male; Mice; Mice, Nude; Microtubules; Models, Molecular; Molecular Conformation; Neoplasms, Experimental; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured

2021
Chemical modifications of ergostane-type triterpenoids from Antrodia camphorata and their cytotoxic activities.
    Bioorganic & medicinal chemistry letters, 2021, 07-01, Volume: 43

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Ergosterol; Humans; Molecular Docking Simulation; Molecular Structure; Polyporales; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triterpenes

2021
Brain metastases from fallopian tube carcinoma responsive to intra-arterial carboplatin and intravenous etoposide: a case report.
    Journal of neuro-oncology, 2001, Volume: 55, Issue:3

    Topics: Adenocarcinoma, Papillary; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem; Carboplatin; Carotid Arteries; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Dacarbazine; Etoposide; Fallopian Tube Neoplasms; Fallopian Tubes; Female; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Magnetic Resonance Imaging; Middle Aged; Paclitaxel; Physical Examination; Rupture, Spontaneous; Temozolomide; Temporal Lobe; Vertebral Artery

2001
Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance.
    Biochemical pharmacology, 2002, Apr-01, Volume: 63, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Carrier Proteins; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dacarbazine; DNA Repair Enzymes; DNA-Binding Proteins; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Glioma; Guanine; Humans; Mismatch Repair Endonuclease PMS2; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Phenotype; Proto-Oncogene Proteins c-bcl-2; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
Immunophenotypical markers, ultrastructure and chemosensitivity profile of metastatic melanoma cells.
    Cancer letters, 2002, Dec-05, Volume: 186, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Cisplatin; Dacarbazine; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Humans; Immunophenotyping; Inhibitory Concentration 50; Interferon alpha-2; Interferon-alpha; Melanoma; Microscopy, Electron; Neoplasm Metastasis; Paclitaxel; Recombinant Proteins; Temozolomide; Time Factors; Tumor Cells, Cultured; Vindesine

2002
Role of body surface area in dosing of investigational anticancer agents in adults, 1991-2001.
    Journal of the National Cancer Institute, 2002, Dec-18, Volume: 94, Issue:24

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Surface Area; Clinical Trials, Phase I as Topic; Cytosine; Dacarbazine; Dioxolanes; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drugs, Investigational; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Paclitaxel; Retrospective Studies; Temozolomide; Uracil

2002
Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
    Neurology, 2003, Mar-11, Volume: 60, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Dacarbazine; Ependymoma; Female; Glioblastoma; Glioma; Humans; Image Enhancement; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Observer Variation; Oligodendroglioma; Paclitaxel; Procarbazine; Sensitivity and Specificity; Temozolomide; Tomography, X-Ray Computed; Treatment Outcome; Vincristine

2003
Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Carboplatin; Cerebral Ventricle Neoplasms; Combined Modality Therapy; Consciousness Disorders; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dacarbazine; Deoxycytidine; Etoposide; Female; Gemcitabine; Germinoma; Hematopoietic Stem Cell Transplantation; Humans; Hypophysectomy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Pituitary Neoplasms; Temozolomide; Thiotepa; Topotecan

2008
Metronomic chemotherapy dosing-schedules with estramustine and temozolomide act synergistically with anti-VEGFR-2 antibody to cause inhibition of human umbilical venous endothelial cell growth.
    Acta oncologica (Stockholm, Sweden), 2007, Volume: 46, Issue:8

    Topics: Antibodies; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cells, Cultured; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Endothelial Cells; Estramustine; Humans; Paclitaxel; Temozolomide; Time Factors; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2

2007
Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3.
    Autophagy, 2008, Volume: 4, Issue:4

    Topics: Animals; Antibodies; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Autophagy; Cell Line, Tumor; Ceramides; Dacarbazine; Female; Glioblastoma; Humans; Mice; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Oxides; Paclitaxel; Phagosomes; Survival Rate; Temozolomide; Transplantation, Heterologous; Tubulin Modulators

2008
Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
    Neuro-oncology, 2009, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Benzothiazoles; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epothilones; Female; Half-Life; Humans; Male; Mice; Mice, Nude; Paclitaxel; Rats; Rats, Wistar; Survival Rate; Temozolomide; Xenograft Model Antitumor Assays

2009
Silencing DNA methyltransferase (DNMT) enhances glioma chemosensitivity.
    Oligonucleotides, 2008, Volume: 18, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Humans; Paclitaxel; RNA, Small Interfering; Telomerase; Temozolomide

2008
Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma.
    Melanoma research, 2009, Volume: 19, Issue:3

    Topics: Aniline Compounds; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dacarbazine; Dasatinib; Drug Synergism; Enzyme Activation; Humans; Inhibitory Concentration 50; Melanoma; Nitriles; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Quinolines; Skin Neoplasms; src-Family Kinases; Temozolomide; Thiazoles

2009
Cell cycle effects and increased adduct formation by temozolomide enhance the effect of cytotoxic and targeted agents in lung cancer cell lines.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Dacarbazine; Deoxycytidine; Deoxyguanosine; DNA Adducts; DNA Methylation; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Mice; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Piperidines; Pyridines; Temozolomide

2009
Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).
    Gene therapy, 2010, Volume: 17, Issue:3

    Topics: Antigens, CD34; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytoprotection; Dacarbazine; Doxorubicin; Genetic Therapy; Genetic Vectors; Hematopoietic Stem Cells; HL-60 Cells; Humans; Lentivirus; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Temozolomide

2010
Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy.
    Oncology reports, 2010, Volume: 24, Issue:4

    Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Administration Schedule; Endothelial Cells; Etoposide; Humans; In Vitro Techniques; Neovascularization, Pathologic; Niacinamide; Paclitaxel; Phenylurea Compounds; Pyridines; Sorafenib; Temozolomide

2010
Glucosylceramide synthase protects glioblastoma cells against autophagic and apoptotic death induced by temozolomide and Paclitaxel.
    Cancer investigation, 2012, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Central Nervous System Neoplasms; Ceramides; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Glucosyltransferases; Humans; Paclitaxel; Temozolomide

2012
Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance.
    The Journal of investigative dermatology, 2012, Volume: 132, Issue:10

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Coloring Agents; Dacarbazine; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Interleukin-8; Melanoma; Mice; Mice, Nude; Paclitaxel; Side-Population Cells; Skin Neoplasms; Temozolomide; Up-Regulation; Xenograft Model Antitumor Assays

2012
Radiation necrosis of a high-grade glioma.
    Medicine and health, Rhode Island, 2012, Volume: 95, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Glioma; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Necrosis; Paclitaxel; Polyglutamic Acid; Temozolomide

2012
F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
    Cancer gene therapy, 2012, Volume: 19, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carmustine; Cell Survival; Cloning, Molecular; Cytoprotection; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Genetic Vectors; Hematopoietic Stem Cells; HL-60 Cells; Humans; K562 Cells; Lentivirus; Nimustine; Paclitaxel; Peptides; Real-Time Polymerase Chain Reaction; Temozolomide; Transgenes; Tumor Suppressor Proteins

2012
Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
    Journal of neuro-oncology, 2013, Volume: 111, Issue:3

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Drug Therapy, Combination; Female; Gels; Glioma; Humans; Neoplasm Transplantation; Paclitaxel; Rats; Rats, Inbred F344; Survival Analysis; Temozolomide

2013
Vulvar and vaginal melanoma: case series and review of current management options including neoadjuvant chemotherapy.
    Gynecologic oncology, 2013, Volume: 129, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Dacarbazine; Female; Humans; Lymphatic Metastasis; Melanoma; Neoadjuvant Therapy; Paclitaxel; Survival Rate; Temozolomide; Treatment Outcome; Vaginal Neoplasms; Vulvar Neoplasms

2013
Biodegradable implants efficiently deliver combination of paclitaxel and temozolomide to glioma C6 cancer cells in vitro.
    Annals of biomedical engineering, 2014, Volume: 42, Issue:1

    Topics: Absorbable Implants; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dacarbazine; Drug Delivery Systems; Glioma; Humans; Paclitaxel; Temozolomide

2014
Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma.
    Biochemical and biophysical research communications, 2013, Nov-01, Volume: 440, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Humans; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Paclitaxel; Reactive Oxygen Species; Temozolomide

2013
c-Myc modulation: a key role in melanoma drug response.
    Cancer biology & therapy, 2015, Volume: 16, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dacarbazine; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression; Humans; Hydrogen Peroxide; Melanoma; Paclitaxel; Protein Phosphatase 2; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-myc; Skin Neoplasms; Temozolomide

2015
Comparative healthcare costs in patients with metastatic melanoma in the USA.
    Melanoma research, 2015, Volume: 25, Issue:4

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Dacarbazine; Female; Health Care Costs; Humans; Immunotherapy; Indoles; Ipilimumab; Male; Managed Care Programs; Melanoma; Middle Aged; Molecular Targeted Therapy; Paclitaxel; Retrospective Studies; Skin Neoplasms; Sulfonamides; Temozolomide; United States; Vemurafenib

2015
The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment.
    International journal of oncology, 2015, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Glioblastoma; Humans; Paclitaxel; Temozolomide

2015
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.
    Oncotarget, 2015, May-20, Volume: 6, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Dacarbazine; Doxorubicin; Genotype; Glioblastoma; Humans; Kaplan-Meier Estimate; Paclitaxel; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proteins; Temozolomide; Valproic Acid

2015
Combination of temozolomide and Taxol exerts a synergistic inhibitory effect on Taxol‑resistant glioma cells via inhibition of glucose metabolism.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Drug Synergism; Glioma; Glucose; Humans; Paclitaxel; Temozolomide

2015
Polymer Nanocomposites Based Thermo-Sensitive Gel for Paclitaxel and Temozolomide Co-Delivery to Glioblastoma Cells.
    Journal of nanoscience and nanotechnology, 2015, Volume: 15, Issue:12

    Topics: Animals; Cell Line, Tumor; Dacarbazine; Drug Carriers; Glioblastoma; Humans; Nanocomposites; Paclitaxel; Polyesters; Polyethylene Glycols; Rats; Temozolomide

2015
The synergic antitumor effects of paclitaxel and temozolomide co-loaded in mPEG-PLGA nanoparticles on glioblastoma cells.
    Oncotarget, 2016, Apr-12, Volume: 7, Issue:15

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Dacarbazine; Drug Carriers; Drug Delivery Systems; Drug Synergism; Female; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols; Rats; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery t
    Oncotarget, 2016, 09-27, Volume: 7, Issue:39

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemotaxis; Cyclic GMP-Dependent Protein Kinase Type I; Dacarbazine; Doxorubicin; Female; Glioblastoma; Glioma; Humans; Male; Mice; Mice, Transgenic; Neoplasm Invasiveness; Neoplastic Stem Cells; Neurons; Oligonucleotide Array Sequence Analysis; Paclitaxel; Phenotype; Stem Cells; Temozolomide

2016
Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 05-28, Volume: 254

    Topics: Adipocytes; Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Dacarbazine; Drug Carriers; Drug Liberation; Glioblastoma; Humans; Lactic Acid; Magnetite Nanoparticles; Male; Mice, Inbred C57BL; Molecular Targeted Therapy; Oleic Acid; Paclitaxel; Particle Size; Permeability; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stem Cells; Surface Properties; Temozolomide; Tissue Distribution

2017
Thermoresponsive nanocomposite gel for local drug delivery to suppress the growth of glioma by inducing autophagy.
    Autophagy, 2017, Jul-03, Volume: 13, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Synergism; Glioma; Hydrogels; Male; Nanocomposites; Nanoparticles; Paclitaxel; Rats; Rats, Wistar; Temozolomide; Temperature

2017
Inhibited, trapped or adducted: the optimal selective synthetic lethal mix for BRCAness.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 01-01, Volume: 29, Issue:1

    Topics: Benzimidazoles; Breast Neoplasms; Carboplatin; Humans; Neoplasm Recurrence, Local; Paclitaxel; Temozolomide

2018
The clinical conundrum of managing relapsed small cell lung cancer.
    Cancer, 2019, 04-01, Volume: 125, Issue:7

    Topics: Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Benzodiazepinones; Carboplatin; Clinical Decision-Making; Disease Progression; Etoposide; Humans; Immunoconjugates; Irinotecan; Liver Neoplasms; Lung Neoplasms; Molecular Targeted Therapy; Neoplasm Recurrence, Local; Nivolumab; Paclitaxel; Piperazines; Pyrimidines; Salvage Therapy; Small Cell Lung Carcinoma; Temozolomide; Thiourea; Topotecan

2019
Codelivery of paclitaxel and temozolomide through a photopolymerizable hydrogel prevents glioblastoma recurrence after surgical resection.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Combinations; Drug Delivery Systems; Female; Glioblastoma; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Mice, Nude; Neoplasm Recurrence, Local; Paclitaxel; Temozolomide

2019
A local combination therapy to inhibit GBM recurrence.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Hydrogels; Neoplasm Recurrence, Local; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Temozolomide

2019
All-stage precisional glioma targeted therapy enabled by a well-designed D-peptide.
    Theranostics, 2020, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Endoplasmic Reticulum Chaperone BiP; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Micelles; Paclitaxel; Peptides; Polyethylene Glycols; Rats, Sprague-Dawley; Sesquiterpenes; Temozolomide

2020
Transcatheter arterial infusion of anti-programmed cell death 1 antibody pembrolizumab combined with temozolomide or nab-paclitaxel in patient with primary anorectal malignant melanoma: Four case reports.
    Journal of cancer research and therapeutics, 2020, Volume: 16, Issue:2

    Topics: Adult; Albumins; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Female; Humans; Infusions, Intra-Arterial; Melanoma; Middle Aged; Paclitaxel; Patient Safety; Rectal Neoplasms; Temozolomide; Treatment Outcome

2020
Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma.
    PloS one, 2020, Volume: 15, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Central Nervous System; Drug Carriers; Glioblastoma; Humans; Hydrogels; Mice; Mice, Inbred NOD; Mice, SCID; Paclitaxel; Peptides; Survival Rate; Temozolomide; Xenograft Model Antitumor Assays

2020
Fabrication of poly(acrylic acid) grafted-chitosan/polyurethane/magnetic MIL-53 metal organic framework composite core-shell nanofibers for co-delivery of temozolomide and paclitaxel against glioblastoma cancer cells.
    International journal of pharmaceutics, 2020, Sep-25, Volume: 587

    Topics: Acrylic Resins; Cell Line, Tumor; Chitosan; Glioblastoma; Humans; Magnetic Phenomena; Metal-Organic Frameworks; Nanofibers; Paclitaxel; Polyurethanes; Temozolomide

2020
Evaluation of hepatic drug-metabolism for glioblastoma using liver-brain chip.
    Biotechnology letters, 2021, Volume: 43, Issue:2

    Topics: Astrocytes; Blood-Brain Barrier; Brain; Capecitabine; Coculture Techniques; Endothelial Cells; Glioblastoma; Hep G2 Cells; Humans; Inactivation, Metabolic; Lab-On-A-Chip Devices; Liver; Nanoparticles; Paclitaxel; Temozolomide

2021
Tailoring drug co-delivery nanosystem for mitigating U-87 stem cells drug resistance.
    Drug delivery and translational research, 2022, Volume: 12, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dendrimers; Drug Resistance; Drug Resistance, Neoplasm; Glioblastoma; Humans; Paclitaxel; Stem Cells; Temozolomide

2022
Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme.
    Scientific reports, 2023, 03-29, Volume: 13, Issue:1

    Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Humans; Hydrogels; Nanocomposites; Nanoparticles; Neoplasm Recurrence, Local; Paclitaxel; Temozolomide

2023
Modulating Wnt/β-Catenin Signaling Pathway on U251 and T98G Glioblastoma Cell Lines Using a Combination of Paclitaxel and Temozolomide, A Molecular Docking Simulations and Gene Expression Study.
    Chemical & pharmaceutical bulletin, 2023, Volume: 71, Issue:10

    Topics: beta Catenin; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression; Glioblastoma; Glycogen Synthase Kinase 3 beta; Humans; Molecular Docking Simulation; Paclitaxel; Temozolomide; Wnt Signaling Pathway

2023