temozolomide has been researched along with paclitaxel in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 16 (22.22) | 29.6817 |
2010's | 45 (62.50) | 24.3611 |
2020's | 11 (15.28) | 2.80 |
Authors | Studies |
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Lombardo, F; Obach, RS; Waters, NJ | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Bakalara, N; Clarion, L; Filippini, D; Hirlemann, MH; Jacquard, C; Lecouvey, M; Loiseau, S; Pirat, JL; Sainte-Catherine, O; Virieux, D; Volle, JN | 1 |
Chen, J; Hosni-Ahmed, A; Jones, TS; Li, W; Li, XS; Miller, DD; Patil, R; Patil, SA; Seibel, WL; Wang, J | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Aksenov, AV; Aksenov, NA; Aksenova, IV; Brenner, AJ; Bryan, BA; Cavazos, DA; Correa, J; De Carvalho, A; Frolova, LV; Johnston, RK; Kiss, R; Kornienko, A; Lefranc, F; Magedov, IV; Mathieu, V; Nguyen, G; Pendleton, AL; Reisenauer, MR; Rogelj, S; Rubin, M; Smirnov, AN | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Aksenov, AV; Brenner, AJ; Cavazos, DA; Cencic, R; Dasari, R; Evidente, A; Frolova, LV; Henry, S; Kidner, R; Kiss, R; Kornienko, A; Lefranc, F; Ma, X; Magedov, IV; Mathieu, V; Pelletier, J; Pertsemlidis, A; Reisenauer, MR; Rogelj, S; Yu, X | 1 |
Liu, Y; Xu, Z; Zhao, SJ | 1 |
Chen, HC; Dai, Z; Liu, H; Liu, HY; Liu, YP; Luo, XD; Wang, B; Yan, H; Yang, D; Zhao, LX; Zhao, XD; Zhao, YL; Zhu, PF; Zhu, YY | 1 |
Gangjee, A; Hamel, E; Ihnat, MA; Luckett-Chastain, LR; Mooberry, SL; Quadery, TM; Xiang, W | 1 |
Kuang, Y; Li, B; Liang, L; Qiao, X; Ye, M; Yi, Y | 1 |
Bafaloukos, D; Briassoulis, E; Fountzilas, G; Georgoulias, V; Gogas, H; Kalofonos, Ch; Karabelis, A; Kosmidis, P; Samantas, E; Skarlos, D | 1 |
Newton, HB; Santi, M; Stevens, C | 1 |
Berman, E; Gallo, JM; Ma, J; Murphy, M; O'Dwyer, PJ; Reed, K | 1 |
Cappugi, P; Coronnello, M; Giannotti, B; Mini, E; Pimpinelli, N; Prignano, F | 1 |
Li, Y; McClay, EF | 1 |
Baker, SD; Donehower, RC; Grochow, LB; Rowinsky, EK; Schellens, JH; Sparreboom, A; Verweij, J | 1 |
Baayen, HC; Barkhof, F; Boogerd, W; Castelijns, JA; Elkhuizen, PH; Heimans, JJ; Postma, TJ; Uitdehaag, BM; Vos, MJ | 1 |
Azzabi, A; Boddy, AV; Calvert, AH; Calvert, PM; Fishwick, K; Griffin, MJ; Hughes, AN; Kelly, C; Lind, MJ; Maraveyas, A; Plummer, ER; Todd, R | 1 |
Fangusaro, J; Finlay, J; Rook, J; Rosser, T | 1 |
Greenman, J; Hetherington, JW; Lam, T; Little, S; Maraveyas, A | 1 |
Aldape, K; Aoki, H; Bogler, O; Conrad, C; Hess, K; Hollingsworth, EF; Iwado, E; Kobayashi, R; Kondo, S; Kondo, Y; Mills, G; Sawaya, R; Shingu, T; Shinojima, N; Tamada, Y; Yamamoto, A; Yokoyama, T; Zhang, L | 1 |
Fichtner, I; Hess-Stumpp, H; Hoffmann, J; Hofmann, B; Klar, U; Lemm, M; Lienau, P; Rotgeri, A | 1 |
Patel, R; Shervington, A | 1 |
Cubitt, CL; Daud, AI; Homsi, J; Jove, R; Messina, JL; Munster, PN; Sullivan, DM; Yu, H; Zhang, S | 1 |
Adema, AD; Honeywell, RJ; Peters, GJ; van der Born, K | 1 |
Fruehauf, S; Laufs, S; Maier, P; Spier, I; Veldwijk, MR; Wenz, F; Zeller, WJ | 1 |
Cawkwell, L; Little, SJ; Maraveyas, A; Murray, A; Stanley, P | 1 |
Lee, FC; Mangalik, A; Movva, S; Parks, V; Rabinowitz, I; Verschraegen, CF | 1 |
Anelli, V; Bassi, R; Brioschi, L; Campanella, R; Caroli, M; De Zen, F; Gaini, SM; Giussani, P; Riboni, L; Riccitelli, E; Viani, P | 1 |
Ahn, NG; Dallaglio, K; Ellis, LZ; Fujita, M; Gonzalez, R; Lewis, KD; Liu, W; Luo, Y; McCarter, MD; Norris, DA; Robinson, SE; Robinson, WA; Roop, DR; Spritz, RA; Takeda, M | 1 |
Boxerman, J; Jeyapalan, S; Raghavan, D; Rogg, J | 1 |
Amatruda, TT; Cohen, PA; Geoffroy, FJ; Gross, HM; Jaslowski, AJ; Kaur, JS; Kosel, ML; Kottschade, LA; Markovic, SN; McWilliams, RR; Perez, DG; Suman, VJ | 1 |
Allgayer, H; Fruehauf, S; Heckmann, D; Laufs, S; Maier, P; Spier, I; Wenz, F; Zeller, WJ; Zucknick, M | 1 |
Chang, J; Cheng, X; Escano, C; Gandhi, A; Kannan, R; Liebes, L; Madden, K; Mendoza, S; Muren, C; Ott, PA; Pavlick, AC; Shao, Y | 1 |
Brem, H; Eberhart, CG; Fowers, KD; Hwang, L; Li, KW; Okonma, S; Recinos, VR; Tyler, BM; Vellimana, AK; Zhang, Y | 1 |
Boxerman, J; Cielo, D; Constantinou, M; Dipetrillo, T; Donahue, J; Elinzano, H; Evans, D; Goldman, M; Isdale, D; Jeyapalan, S; Kinsella, T; Mantripragada, K; Oyelese, A; Puthawala, Y; Rosati, K; Safran, H; Santaniello, A; Stopa, E | 1 |
Cliby, WA; Janco, JM; Markovic, SN; Weaver, AL | 1 |
Fan, X; Li, X; Ni, S; Qi, H; Wang, J | 1 |
Kim, SS; Kim, SY; Lim, SH; Seong, S | 1 |
Koon, HB; Megahed, AI | 1 |
Alfano, D; Caputo, E; Cavalcanti, E; Fico, A; Patriarca, EJ; Travali, S; Valentino, A; Vasta, V | 1 |
Abhyankar, S; Chang, CL; Donga, P; Munakata, J; Reyes, CM; Schabert, VF; Yim, YM | 1 |
Annovazzi, L; Battaglia, L; Caldera, V; Chirio, D; Melcarne, A; Mellai, M; Riganti, C; Schiffer, D | 1 |
Annovazzi, L; Biunno, I; Cassoni, P; Cattaneo, M; De Blasio, P; Melcarne, A; Mellai, M; Schiffer, D; Storaci, AM | 1 |
Chen, HM; Guan, DG; Liao, SF; Zhao, TZ | 1 |
Duan, Y; Gao, P; Shen, M; Sun, Y; Xu, Y | 1 |
Duan, Y; Li, Y; Shen, M; Sun, Y; Teng, Y; Wang, Y; Xu, Y | 1 |
Castro, MG; Doherty, R; Lowenstein, PR; Wilson, TJ; Zamler, DB | 1 |
Blank, C; Cranmer, L; Daud, A; Dummer, R; Ebbinghaus, S; Hamid, O; Hauschild, A; Hille, D; Kang, SP; Loquai, C; Mehnert, JM; O'Day, S; Puzanov, I; Ribas, A; Robert, C; Salama, A; Schachter, J; Schadendorf, D; van den Eertwegh, A; Zhou, W | 1 |
Diéras, V; Domchek, SM; Friedlander, M; Garber, JE; Giranda, VL; Han, HS; Isakoff, SJ; Johnson, EF; Kaufman, B; Maag, D; Puhalla, S; Qin, Q; Robson, M; Shepherd, SP; Telli, ML | 1 |
Chang, CW; Chen, HH; Chiang, CS; Chiang, WH; Chiu, HC; Huang, WC; Lin, YW; Lu, IL; Tsai, YC | 1 |
Chen, J; Ding, L; Duan, Y; Huang, C; Li, R; Shen, M; Sun, Y; Wang, Q; Zhang, X | 1 |
Bondarenko, I; Campone, M; Chmielowska, E; Citrin, D; Diéras, V; Domchek, SM; Friedlander, M; Garber, JE; Gradishar, W; Han, HS; Isakoff, SJ; Jager, A; Jakobsen, EH; Kaklamani, V; Kaufman, B; Marcom, PK; Nickner, C; Palácová, M; Puhalla, S; Qian, J; Qin, Q; Ratajczak, CK; Robson, M; Shepherd, SP; Shparyk, Y; Telli, ML | 1 |
Tutt, A | 1 |
Chmielowski, B; Copley-Merriman, C; Liu, FX; Mauskopf, J; Stevinson, K; Wang, J; Zimovetz, EA | 1 |
Nazha, B; Owonikoko, TK | 1 |
Specenier, P | 1 |
Bozzato, E; Danhier, F; Gallez, B; Ghiassinejad, S; Joudiou, N; Préat, V; Zhao, M | 1 |
Schwendeman, SP | 1 |
Franken, MG; Gheorghe, M; Haanen, JBAG; Leeneman, B; Uyl-de Groot, CA; van Baal, PHM | 1 |
Chai, Z; Li, J; Lu, L; Lu, W; Mao, J; Ran, D; Wu, S; Xie, C; Zhan, C; Zhang, Y; Zhou, J | 1 |
Cao, F; Chen, S; Fan, W; Li, D; Ma, W; Qi, H; Shen, L; Song, Z; Wen, X; Wu, Y; Xie, L; Zhang, X | 1 |
Bernstein, AM; Deming, TJ; Garrett, MC; Hung, D; Kornblum, HI; O'Shea, TM; Sofroniew, MV; Soto, H; Staarman, B; Wollenberg, AL | 1 |
Bazzazzadeh, A; Dizaji, BF; Irani, M; Kianinejad, N; Nouri, A | 1 |
Guo, Y; Li, D; Li, Z; Su, W; Wang, Y | 1 |
Behrooz, AB; Masarudin, MJ; Masomian, M; Sekawi, Z; Syahir, A; Tajudin, AA; Vazifehmand, R | 1 |
Erthal, LCS; Gobbo, OL; Ruiz-Hernandez, E; Shi, Y; Sweeney, KJ | 1 |
Alinezhad, A; Behrooz, AB; Davazdahemami, AA; Hamzah, ASA; Homaie, FM; Jamalpour, S; Maddah, SM; Sabah, JT; Vazifehmand, R | 1 |
7 review(s) available for temozolomide and paclitaxel
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles | 2019 |
Systemic chemotherapy for the treatment of metastatic melanoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carmustine; Cisplatin; Clinical Trials as Topic; Dacarbazine; Humans; Melanoma; Nitrosourea Compounds; Paclitaxel; Tamoxifen; Taxoids; Temozolomide | 2002 |
What is the role of chemotherapy in the treatment of melanoma?
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Carboplatin; Cisplatin; Clinical Trials as Topic; Dacarbazine; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Immunosuppression Therapy; Immunotherapy; Ipilimumab; Melanoma; Paclitaxel; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Temozolomide; Treatment Outcome | 2014 |
Direct costs associated with adverse events of systemic therapies for advanced melanoma: Systematic literature review.
Topics: Antineoplastic Agents; Dacarbazine; Health Expenditures; Health Resources; Humans; Indoles; Ipilimumab; Melanoma; Paclitaxel; Sulfonamides; Temozolomide; Vemurafenib | 2018 |
Efficacy of nab-paclitaxel in treating metastatic melanoma.
Topics: Albumins; Animals; Antineoplastic Agents, Phytogenic; Dacarbazine; Humans; Melanoma; Paclitaxel; Temozolomide | 2019 |
A systematic literature review and network meta-analysis of effectiveness and safety outcomes in advanced melanoma.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azetidines; Benzimidazoles; Cancer Vaccines; Carboplatin; Dacarbazine; gp100 Melanoma Antigen; Humans; Hydrazines; Imidazoles; Interleukin-2; Ipilimumab; Lenalidomide; Melanoma; Network Meta-Analysis; Nitrosourea Compounds; Nivolumab; Organophosphorus Compounds; Oximes; Paclitaxel; Piperidines; Progression-Free Survival; Proportional Hazards Models; Pyridones; Pyrimidinones; Skin Neoplasms; Sorafenib; Survival Rate; Temozolomide; Treatment Outcome; Vemurafenib | 2019 |
9 trial(s) available for temozolomide and paclitaxel
Article | Year |
---|---|
Temozolomide in combination with docetaxel in patients with advanced melanoma: a phase II study of the Hellenic Cooperative Oncology Group.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Docetaxel; Female; Humans; Infusions, Intravenous; Male; Melanoma; Middle Aged; Neutropenia; Paclitaxel; Skin Neoplasms; Taxoids; Temozolomide; Thrombocytopenia | 2002 |
Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Paclitaxel; Temozolomide | 2005 |
Phase I dose finding study of carboplatin, paclitaxel, and temozolomide in advanced solid tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cohort Studies; Dacarbazine; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Paclitaxel; Skin Neoplasms; Small Cell Lung Carcinoma; Temozolomide | 2011 |
A randomized phase 2 study of temozolomide and bevacizumab or nab-paclitaxel, carboplatin, and bevacizumab in patients with unresectable stage IV melanoma : a North Central Cancer Treatment Group study, N0775.
Topics: Adult; Aged; Aged, 80 and over; Albumins; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carboplatin; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Paclitaxel; Skin Neoplasms; Survival Analysis; Temozolomide; Treatment Outcome; Young Adult | 2013 |
Oblimersen in combination with temozolomide and albumin-bound paclitaxel in patients with advanced melanoma: a phase I trial.
Topics: Adult; Aged; Albumin-Bound Paclitaxel; Albumins; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Dacarbazine; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Oligonucleotides, Antisense; Paclitaxel; Skin Neoplasms; Temozolomide; Thionucleotides; Treatment Outcome | 2013 |
Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Male; Middle Aged; Paclitaxel; Polyglutamic Acid; Survival Analysis; Temozolomide | 2014 |
Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dacarbazine; Disease-Free Survival; Female; Health Status; Humans; Male; Melanoma; Middle Aged; Paclitaxel; Patient Reported Outcome Measures; Quality of Life; Skin Neoplasms; Temozolomide; Young Adult | 2016 |
A randomized Phase II study of veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in BRCA1/2 metastatic breast cancer: design and rationale.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Carboplatin; Clinical Protocols; Dacarbazine; Drug Monitoring; Female; Humans; Models, Statistical; Paclitaxel; Research Design; Sample Size; Temozolomide | 2017 |
Veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in patients with BRCA1/2 locally recurrent/metastatic breast cancer: randomized phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Breast Neoplasms, Male; Carboplatin; Female; Genes, BRCA1; Genes, BRCA2; Germ-Line Mutation; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Paclitaxel; Placebos; Single-Blind Method; Temozolomide; Young Adult | 2018 |
56 other study(ies) available for temozolomide and paclitaxel
Article | Year |
---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Oxaphosphinanes: new therapeutic perspectives for glioblastoma.
Topics: Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Survival; Cyclic P-Oxides; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Organophosphonates; Phosphorous Acids; Rats; Stereoisomerism; Structure-Activity Relationship | 2012 |
New substituted 4H-chromenes as anticancer agents.
Topics: Antineoplastic Agents; Astrocytes; Benzopyrans; Binding Sites; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Drug Screening Assays, Antitumor; Humans; Oligopeptides; Protein Structure, Tertiary; Tubulin; Tubulin Modulators | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Activity of 2-aryl-2-(3-indolyl)acetohydroxamates against drug-resistant cancer cells.
Topics: Antineoplastic Agents; Cell Differentiation; Cells, Cultured; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fibroblasts; Humans; Hydroxamic Acids; Indoles; Neoplasms; Neoplastic Stem Cells; Structure-Activity Relationship | 2015 |
5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells.
Topics: Amaryllidaceae; Amaryllidaceae Alkaloids; Antineoplastic Agents; Drug Resistance, Neoplasm; Humans; Plant Extracts; Tumor Cells, Cultured | 2016 |
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.
Topics: Antineoplastic Agents; Apoptosis; Biological Products; Brain Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioblastoma; Goosecoid Protein; Humans; Molecular Structure; Saponins; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cyclopentanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Glioma; Humans; Male; Mice; Mice, Nude; Microtubules; Models, Molecular; Molecular Conformation; Neoplasms, Experimental; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Chemical modifications of ergostane-type triterpenoids from Antrodia camphorata and their cytotoxic activities.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Ergosterol; Humans; Molecular Docking Simulation; Molecular Structure; Polyporales; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triterpenes | 2021 |
Brain metastases from fallopian tube carcinoma responsive to intra-arterial carboplatin and intravenous etoposide: a case report.
Topics: Adenocarcinoma, Papillary; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem; Carboplatin; Carotid Arteries; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Dacarbazine; Etoposide; Fallopian Tube Neoplasms; Fallopian Tubes; Female; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Magnetic Resonance Imaging; Middle Aged; Paclitaxel; Physical Examination; Rupture, Spontaneous; Temozolomide; Temporal Lobe; Vertebral Artery | 2001 |
Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Carrier Proteins; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dacarbazine; DNA Repair Enzymes; DNA-Binding Proteins; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Glioma; Guanine; Humans; Mismatch Repair Endonuclease PMS2; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Phenotype; Proto-Oncogene Proteins c-bcl-2; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Immunophenotypical markers, ultrastructure and chemosensitivity profile of metastatic melanoma cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Cisplatin; Dacarbazine; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Humans; Immunophenotyping; Inhibitory Concentration 50; Interferon alpha-2; Interferon-alpha; Melanoma; Microscopy, Electron; Neoplasm Metastasis; Paclitaxel; Recombinant Proteins; Temozolomide; Time Factors; Tumor Cells, Cultured; Vindesine | 2002 |
Role of body surface area in dosing of investigational anticancer agents in adults, 1991-2001.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Surface Area; Clinical Trials, Phase I as Topic; Cytosine; Dacarbazine; Dioxolanes; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drugs, Investigational; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Paclitaxel; Retrospective Studies; Temozolomide; Uracil | 2002 |
Interobserver variability in the radiological assessment of response to chemotherapy in glioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Dacarbazine; Ependymoma; Female; Glioblastoma; Glioma; Humans; Image Enhancement; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Observer Variation; Oligodendroglioma; Paclitaxel; Procarbazine; Sensitivity and Specificity; Temozolomide; Tomography, X-Ray Computed; Treatment Outcome; Vincristine | 2003 |
Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Carboplatin; Cerebral Ventricle Neoplasms; Combined Modality Therapy; Consciousness Disorders; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dacarbazine; Deoxycytidine; Etoposide; Female; Gemcitabine; Germinoma; Hematopoietic Stem Cell Transplantation; Humans; Hypophysectomy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Pituitary Neoplasms; Temozolomide; Thiotepa; Topotecan | 2008 |
Metronomic chemotherapy dosing-schedules with estramustine and temozolomide act synergistically with anti-VEGFR-2 antibody to cause inhibition of human umbilical venous endothelial cell growth.
Topics: Antibodies; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cells, Cultured; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Endothelial Cells; Estramustine; Humans; Paclitaxel; Temozolomide; Time Factors; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2 | 2007 |
Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3.
Topics: Animals; Antibodies; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Autophagy; Cell Line, Tumor; Ceramides; Dacarbazine; Female; Glioblastoma; Humans; Mice; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Oxides; Paclitaxel; Phagosomes; Survival Rate; Temozolomide; Transplantation, Heterologous; Tubulin Modulators | 2008 |
Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Benzothiazoles; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Epothilones; Female; Half-Life; Humans; Male; Mice; Mice, Nude; Paclitaxel; Rats; Rats, Wistar; Survival Rate; Temozolomide; Xenograft Model Antitumor Assays | 2009 |
Silencing DNA methyltransferase (DNMT) enhances glioma chemosensitivity.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Humans; Paclitaxel; RNA, Small Interfering; Telomerase; Temozolomide | 2008 |
Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma.
Topics: Aniline Compounds; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dacarbazine; Dasatinib; Drug Synergism; Enzyme Activation; Humans; Inhibitory Concentration 50; Melanoma; Nitriles; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Quinolines; Skin Neoplasms; src-Family Kinases; Temozolomide; Thiazoles | 2009 |
Cell cycle effects and increased adduct formation by temozolomide enhance the effect of cytotoxic and targeted agents in lung cancer cell lines.
Topics: Animals; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Dacarbazine; Deoxycytidine; Deoxyguanosine; DNA Adducts; DNA Methylation; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Mice; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Piperidines; Pyridines; Temozolomide | 2009 |
Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).
Topics: Antigens, CD34; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytoprotection; Dacarbazine; Doxorubicin; Genetic Therapy; Genetic Vectors; Hematopoietic Stem Cells; HL-60 Cells; Humans; Lentivirus; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Temozolomide | 2010 |
Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy.
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Administration Schedule; Endothelial Cells; Etoposide; Humans; In Vitro Techniques; Neovascularization, Pathologic; Niacinamide; Paclitaxel; Phenylurea Compounds; Pyridines; Sorafenib; Temozolomide | 2010 |
Glucosylceramide synthase protects glioblastoma cells against autophagic and apoptotic death induced by temozolomide and Paclitaxel.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Central Nervous System Neoplasms; Ceramides; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Glucosyltransferases; Humans; Paclitaxel; Temozolomide | 2012 |
Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Coloring Agents; Dacarbazine; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Interleukin-8; Melanoma; Mice; Mice, Nude; Paclitaxel; Side-Population Cells; Skin Neoplasms; Temozolomide; Up-Regulation; Xenograft Model Antitumor Assays | 2012 |
Radiation necrosis of a high-grade glioma.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Glioma; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Necrosis; Paclitaxel; Polyglutamic Acid; Temozolomide | 2012 |
F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carmustine; Cell Survival; Cloning, Molecular; Cytoprotection; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Genetic Vectors; Hematopoietic Stem Cells; HL-60 Cells; Humans; K562 Cells; Lentivirus; Nimustine; Paclitaxel; Peptides; Real-Time Polymerase Chain Reaction; Temozolomide; Transgenes; Tumor Suppressor Proteins | 2012 |
Combination of paclitaxel thermal gel depot with temozolomide and radiotherapy significantly prolongs survival in an experimental rodent glioma model.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Drug Therapy, Combination; Female; Gels; Glioma; Humans; Neoplasm Transplantation; Paclitaxel; Rats; Rats, Inbred F344; Survival Analysis; Temozolomide | 2013 |
Vulvar and vaginal melanoma: case series and review of current management options including neoadjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Dacarbazine; Female; Humans; Lymphatic Metastasis; Melanoma; Neoadjuvant Therapy; Paclitaxel; Survival Rate; Temozolomide; Treatment Outcome; Vaginal Neoplasms; Vulvar Neoplasms | 2013 |
Biodegradable implants efficiently deliver combination of paclitaxel and temozolomide to glioma C6 cancer cells in vitro.
Topics: Absorbable Implants; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dacarbazine; Drug Delivery Systems; Glioma; Humans; Paclitaxel; Temozolomide | 2014 |
Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Humans; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Paclitaxel; Reactive Oxygen Species; Temozolomide | 2013 |
c-Myc modulation: a key role in melanoma drug response.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dacarbazine; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression; Humans; Hydrogen Peroxide; Melanoma; Paclitaxel; Protein Phosphatase 2; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-myc; Skin Neoplasms; Temozolomide | 2015 |
Comparative healthcare costs in patients with metastatic melanoma in the USA.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Dacarbazine; Female; Health Care Costs; Humans; Immunotherapy; Indoles; Ipilimumab; Male; Managed Care Programs; Melanoma; Middle Aged; Molecular Targeted Therapy; Paclitaxel; Retrospective Studies; Skin Neoplasms; Sulfonamides; Temozolomide; United States; Vemurafenib | 2015 |
The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Glioblastoma; Humans; Paclitaxel; Temozolomide | 2015 |
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Dacarbazine; Doxorubicin; Genotype; Glioblastoma; Humans; Kaplan-Meier Estimate; Paclitaxel; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proteins; Temozolomide; Valproic Acid | 2015 |
Combination of temozolomide and Taxol exerts a synergistic inhibitory effect on Taxol‑resistant glioma cells via inhibition of glucose metabolism.
Topics: Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Drug Synergism; Glioma; Glucose; Humans; Paclitaxel; Temozolomide | 2015 |
Polymer Nanocomposites Based Thermo-Sensitive Gel for Paclitaxel and Temozolomide Co-Delivery to Glioblastoma Cells.
Topics: Animals; Cell Line, Tumor; Dacarbazine; Drug Carriers; Glioblastoma; Humans; Nanocomposites; Paclitaxel; Polyesters; Polyethylene Glycols; Rats; Temozolomide | 2015 |
The synergic antitumor effects of paclitaxel and temozolomide co-loaded in mPEG-PLGA nanoparticles on glioblastoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Dacarbazine; Drug Carriers; Drug Delivery Systems; Drug Synergism; Female; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols; Rats; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery t
Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemotaxis; Cyclic GMP-Dependent Protein Kinase Type I; Dacarbazine; Doxorubicin; Female; Glioblastoma; Glioma; Humans; Male; Mice; Mice, Transgenic; Neoplasm Invasiveness; Neoplastic Stem Cells; Neurons; Oligonucleotide Array Sequence Analysis; Paclitaxel; Phenotype; Stem Cells; Temozolomide | 2016 |
Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma.
Topics: Adipocytes; Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Dacarbazine; Drug Carriers; Drug Liberation; Glioblastoma; Humans; Lactic Acid; Magnetite Nanoparticles; Male; Mice, Inbred C57BL; Molecular Targeted Therapy; Oleic Acid; Paclitaxel; Particle Size; Permeability; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stem Cells; Surface Properties; Temozolomide; Tissue Distribution | 2017 |
Thermoresponsive nanocomposite gel for local drug delivery to suppress the growth of glioma by inducing autophagy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Synergism; Glioma; Hydrogels; Male; Nanocomposites; Nanoparticles; Paclitaxel; Rats; Rats, Wistar; Temozolomide; Temperature | 2017 |
Inhibited, trapped or adducted: the optimal selective synthetic lethal mix for BRCAness.
Topics: Benzimidazoles; Breast Neoplasms; Carboplatin; Humans; Neoplasm Recurrence, Local; Paclitaxel; Temozolomide | 2018 |
The clinical conundrum of managing relapsed small cell lung cancer.
Topics: Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Benzodiazepinones; Carboplatin; Clinical Decision-Making; Disease Progression; Etoposide; Humans; Immunoconjugates; Irinotecan; Liver Neoplasms; Lung Neoplasms; Molecular Targeted Therapy; Neoplasm Recurrence, Local; Nivolumab; Paclitaxel; Piperazines; Pyrimidines; Salvage Therapy; Small Cell Lung Carcinoma; Temozolomide; Thiourea; Topotecan | 2019 |
Codelivery of paclitaxel and temozolomide through a photopolymerizable hydrogel prevents glioblastoma recurrence after surgical resection.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Combinations; Drug Delivery Systems; Female; Glioblastoma; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Mice, Nude; Neoplasm Recurrence, Local; Paclitaxel; Temozolomide | 2019 |
A local combination therapy to inhibit GBM recurrence.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Hydrogels; Neoplasm Recurrence, Local; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Temozolomide | 2019 |
All-stage precisional glioma targeted therapy enabled by a well-designed D-peptide.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Endoplasmic Reticulum Chaperone BiP; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Micelles; Paclitaxel; Peptides; Polyethylene Glycols; Rats, Sprague-Dawley; Sesquiterpenes; Temozolomide | 2020 |
Transcatheter arterial infusion of anti-programmed cell death 1 antibody pembrolizumab combined with temozolomide or nab-paclitaxel in patient with primary anorectal malignant melanoma: Four case reports.
Topics: Adult; Albumins; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Female; Humans; Infusions, Intra-Arterial; Melanoma; Middle Aged; Paclitaxel; Patient Safety; Rectal Neoplasms; Temozolomide; Treatment Outcome | 2020 |
Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Central Nervous System; Drug Carriers; Glioblastoma; Humans; Hydrogels; Mice; Mice, Inbred NOD; Mice, SCID; Paclitaxel; Peptides; Survival Rate; Temozolomide; Xenograft Model Antitumor Assays | 2020 |
Fabrication of poly(acrylic acid) grafted-chitosan/polyurethane/magnetic MIL-53 metal organic framework composite core-shell nanofibers for co-delivery of temozolomide and paclitaxel against glioblastoma cancer cells.
Topics: Acrylic Resins; Cell Line, Tumor; Chitosan; Glioblastoma; Humans; Magnetic Phenomena; Metal-Organic Frameworks; Nanofibers; Paclitaxel; Polyurethanes; Temozolomide | 2020 |
Evaluation of hepatic drug-metabolism for glioblastoma using liver-brain chip.
Topics: Astrocytes; Blood-Brain Barrier; Brain; Capecitabine; Coculture Techniques; Endothelial Cells; Glioblastoma; Hep G2 Cells; Humans; Inactivation, Metabolic; Lab-On-A-Chip Devices; Liver; Nanoparticles; Paclitaxel; Temozolomide | 2021 |
Tailoring drug co-delivery nanosystem for mitigating U-87 stem cells drug resistance.
Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Dendrimers; Drug Resistance; Drug Resistance, Neoplasm; Glioblastoma; Humans; Paclitaxel; Stem Cells; Temozolomide | 2022 |
Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme.
Topics: Adult; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Glioblastoma; Humans; Hydrogels; Nanocomposites; Nanoparticles; Neoplasm Recurrence, Local; Paclitaxel; Temozolomide | 2023 |
Modulating Wnt/β-Catenin Signaling Pathway on U251 and T98G Glioblastoma Cell Lines Using a Combination of Paclitaxel and Temozolomide, A Molecular Docking Simulations and Gene Expression Study.
Topics: beta Catenin; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression; Glioblastoma; Glycogen Synthase Kinase 3 beta; Humans; Molecular Docking Simulation; Paclitaxel; Temozolomide; Wnt Signaling Pathway | 2023 |