temozolomide has been researched along with nimustine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 16 (55.17) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Bardenheuer, W; Flasshove, M; Jansen, M; Moritz, T; Seeber, S; Sorg, UR | 1 |
| Weller, M | 1 |
| Natsume, A; Wakabayashi, T; Yoshida, J | 1 |
| Ogawa, M; Ueda, T; Yamauchi, T | 1 |
| Hidaka, M; Sanada, M; Sekiguchi, M; Takagi, Y; Yoshida, H | 1 |
| Kikuchi, T; Kumabe, T; Sonoda, Y; Sugiyama, S; Tominaga, T; Yamashita, Y | 1 |
| Eisele, G; Happold, C; Linnebank, M; Roth, P; Steinbach, JP; Weller, M; Wick, W | 1 |
| Han, JH; Heo, DS; Jung, HW; Kim, CY; Kim, DG; Kim, DW; Kim, IH; Lee, SH; Paek, SH; Park, CK | 1 |
| Christmann, M; Kaina, B; Nikolova, T | 1 |
| Gong, F; Ji, SP; Li, AM; Tai, JL; Zhang, YP; Zheng, CQ | 1 |
| Fruehauf, S; Laufs, S; Maier, P; Spier, I; Veldwijk, MR; Wenz, F; Zeller, WJ | 1 |
| Jung, S; Jung, TY; Kang, SS; Kim, IY; Kim, YH; Lee, KH; Moon, KS; Park, CS | 1 |
| Inoue, T; Kanamori, M; Kumabe, T; Sonoda, Y; Tominaga, T; Watanabe, M | 1 |
| Hasegawa, M; Helleday, T; Kinashi, Y; Kondo, N; Masunaga, S; Mori, E; Noda, T; Ohnishi, T; Ono, K; Suzuki, M; Takahashi, A; Thompson, LH; Zdzienicka, MZ | 1 |
| Chen, ZP; Jiang, XB; Mu, YG; Sai, K; Shen, D; Yang, QY; Zhang, XH | 1 |
| Aaberg-Jessen, C; Christensen, KG; Jensen, PH; Jensen, SS; Kolenda, J; Kristensen, BW; Nørregaard, A; Schrøder, HD | 1 |
| Hoshimaru, M; Kawanabe, Y; Kihara, S; Koizumi, T; Sasaki, N; Sawada, M; Ueda, S; Yukawa, H | 1 |
| Allgayer, H; Fruehauf, S; Heckmann, D; Laufs, S; Maier, P; Spier, I; Wenz, F; Zeller, WJ; Zucknick, M | 1 |
| Fujii, T; Saito, N; Takahashi, K; Tanaka, M; Todo, T; Tsuno, NH | 1 |
| Chen, B; Chen, L; Chen, X; Jiang, T; Li, S; Wang, J; Wang, L; Wang, Y; Wu, C; Zhang, X; Zhang, Z | 1 |
| Chonan, M; Jokura, H; Kanamori, M; Katakura, R; Kato, H; Kawagishi, J; Kawaguchi, T; Kayama, T; Kumabe, T; Mano, Y; Saito, R; Shibahara, I; Sonoda, Y; Tominaga, T; Watanabe, M; Yamashita, Y | 1 |
| Cui, XL; Li, HL; Lin, S; Zhang, JN | 1 |
| Aasland, D; Berte, N; Christmann, M; Kaina, B; Kitzinger, R; Krämer, OH; Meise, R; Tomicic, MT | 1 |
| Ding, L; Gao, L; Lv, P; Qi, L; Wang, S; Wang, W; Xu, Y; Zhao, D; Zhong, Y | 1 |
| Ishikawa, E; Ishikawa, H; Matsuda, M; Matsumura, A; Mizumoto, M; Okumura, T; Sakurai, H; Takano, S; Tsuboi, K; Yamamoto, T | 1 |
| Bu, XY; Kong, LF; Luo, JC; Ma, CX; Qu, MQ; Wang, YW; Yan, ZY; Yang, DY; Zhao, YW; Zhou, ZL | 1 |
| Chonan, M; Kanamori, M; Nakasato, N; Osawa, SI; Saito, R; Suzuki, H; Tominaga, T; Watanabe, M | 1 |
| Fujii, T; Ichimura, K; Kawauchi, D; Kobayashi, T; Kondo, A; Nakano, T; Narita, Y; Sasaki, N; Satomi, K; Takahashi, M; Tomiyama, A; Uchida, E; Wada, K; Yamamuro, S; Yoshino, A | 1 |
| Bu, XY; Cheng, X; Kong, LF; Luo, JC; Qu, MQ; Wang, YW; Yan, ZY; Yang, DY; Zhao, YW | 1 |
3 review(s) available for temozolomide and nimustine
| Article | Year |
|---|---|
[Standards and new developments in the chemotherapy of glioblastomas].
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Cytarabine; Dacarbazine; Decanoic Acids; DNA Modification Methylases; Glioblastoma; Humans; Nimustine; Polyesters; Promoter Regions, Genetic; Temozolomide; Teniposide | 2005 |
[Glioma].
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Drug Synergism; Genetic Therapy; Glioma; Humans; Interferon-beta; Nimustine; Radiotherapy; Temozolomide | 2006 |
A network meta-analysis: the overall and progression-free survival of glioma patients treated by different chemotherapeutic interventions combined with radiation therapy (RT).
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Cisplatin; Dacarbazine; Disease-Free Survival; Eflornithine; Glioma; Humans; Mitolactol; Network Meta-Analysis; Nimustine; Probability; Randomized Controlled Trials as Topic; Snake Venoms; Temozolomide; Treatment Outcome; Vincristine | 2016 |
3 trial(s) available for temozolomide and nimustine
| Article | Year |
|---|---|
Human umbilical vein endothelial cell vaccine therapy in patients with recurrent glioblastoma.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Dacarbazine; Disease Progression; Disease-Free Survival; Female; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Immunotherapy, Active; Male; Middle Aged; Nimustine; Temozolomide | 2013 |
Chemotherapy alleviates subacute recurrent glioma-associated refractory cerebral edema by downregulating vascular endothelial growth factor.
Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Cisplatin; Dacarbazine; Down-Regulation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Nimustine; Postoperative Complications; Temozolomide; Thrombocytopenia; Treatment Outcome; Vascular Endothelial Growth Factor A; Young Adult | 2014 |
Granulocyte-macrophage colony stimulating factor enhances efficacy of nimustine rendezvousing with temozolomide plus irradiation in patients with glioblastoma.
Topics: Brain Neoplasms; Glioblastoma; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; Macrophage Colony-Stimulating Factor; Neutropenia; Nimustine; Temozolomide; Thrombocytopenia | 2023 |
23 other study(ies) available for temozolomide and nimustine
| Article | Year |
|---|---|
Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
Topics: Alkylating Agents; Alkylation; Animals; Carmustine; Cells, Cultured; Colony-Forming Units Assay; Dacarbazine; DNA Damage; DNA, Complementary; Drug Resistance; Genetic Vectors; Hematopoietic Stem Cells; Humans; Lomustine; Mice; Moloney murine leukemia virus; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Recombinant Fusion Proteins; Retroviridae; Sarcoma Viruses, Murine; Spleen Focus-Forming Viruses; Temozolomide; Terminal Repeat Sequences; Transfection | 2001 |
Carmustine-resistant cancer cells are sensitized to temozolomide as a result of enhanced mismatch repair during the development of carmustine resistance.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cadmium Chloride; Carmustine; Cell Line, Tumor; Cell Proliferation; Comet Assay; Dacarbazine; DNA Mismatch Repair; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Guanine; Humans; Hydroxylamines; Nimustine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Temozolomide | 2008 |
Different initial steps of apoptosis induced by two types of antineoplastic drugs.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Cell Line; Dacarbazine; DNA Damage; DNA Repair; Fibroblasts; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; MutL Protein Homolog 1; Nimustine; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Phosphatidylserines; Structure-Activity Relationship; Temozolomide | 2008 |
Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Convection; Cranial Irradiation; Dacarbazine; Disease Models, Animal; Drug Delivery Systems; Gliosarcoma; Injections, Intraperitoneal; Male; Nimustine; Rats; Rats, Inbred F344; Survival Analysis; Survival Rate; Temozolomide; Treatment Outcome; Xenograft Model Antitumor Assays | 2008 |
ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Nimustine; Temozolomide | 2009 |
Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Dacarbazine; Drug Therapy, Combination; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Staging; Nimustine; Retrospective Studies; Salvage Therapy; Survival Analysis; Temozolomide | 2009 |
FEN1 is overexpressed in testis, lung and brain tumors.
Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Brain Neoplasms; Cisplatin; Dacarbazine; Flap Endonucleases; Flow Cytometry; Humans; Lung Neoplasms; Male; Methyl Methanesulfonate; Nimustine; RNA, Messenger; RNA, Small Interfering; Temozolomide; Testicular Neoplasms | 2009 |
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azacitidine; Brain Neoplasms; Cell Line, Tumor; CpG Islands; Dacarbazine; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Survival Rate; Temozolomide; Young Adult | 2009 |
Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).
Topics: Antigens, CD34; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytoprotection; Dacarbazine; Doxorubicin; Genetic Therapy; Genetic Vectors; Hematopoietic Stem Cells; HL-60 Cells; Humans; Lentivirus; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Temozolomide | 2010 |
Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvant; Cisplatin; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Immunohistochemistry; Male; Microsurgery; Middle Aged; Neoplasm Recurrence, Local; Neurosurgical Procedures; Nimustine; Polymerase Chain Reaction; Promoter Regions, Genetic; Radiotherapy, Adjuvant; Reoperation; Temozolomide; Time Factors; Treatment Outcome; Tumor Suppressor Proteins | 2010 |
Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Fatal Outcome; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Ki-67 Antigen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasms, Neuroepithelial; Neurosurgical Procedures; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Retrospective Studies; Temozolomide; Tumor Suppressor Protein p53; Young Adult | 2010 |
FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ.
Topics: Animals; BRCA2 Protein; Cell Line; Dacarbazine; DNA Damage; DNA Repair; Down-Regulation; Fanconi Anemia; Gene Silencing; Glioblastoma; Humans; Mice; Models, Biological; Nimustine; Rad51 Recombinase; Recombination, Genetic; RNA, Small Interfering; Temozolomide | 2011 |
[Nimotuzumab in combination with chemotherapy for patients with malignant gliomas].
Topics: Adolescent; Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Child; Cisplatin; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Glioma; Humans; Infusions, Intravenous; Male; Nausea; Neutropenia; Nimustine; Temozolomide; Teniposide; Thrombocytopenia; Young Adult | 2011 |
Effects of chemotherapeutics on organotypic corticostriatal slice cultures identified by a panel of fluorescent and immunohistochemical markers.
Topics: Animals; Antineoplastic Agents; Benzamides; Biomarkers; Carrier Proteins; Cell Death; Dacarbazine; Glial Fibrillary Acidic Protein; Imatinib Mesylate; Immunohistochemistry; Indicators and Reagents; Microtubule-Associated Proteins; Neuroglia; Neurons; Nimustine; Piperazines; Propidium; Pyrimidines; Rats; Temozolomide; Vincristine | 2012 |
Radiation-induced spinal cord anaplastic astrocytoma subsequent to radiotherapy for testicular seminoma.
Topics: Antineoplastic Agents; Astrocytoma; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Disease Progression; Fatal Outcome; Humans; Hydrocephalus; Laminectomy; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Nimustine; Seminoma; Spinal Cord Compression; Spinal Cord Neoplasms; Syringomyelia; Temozolomide; Testicular Neoplasms; Thoracic Vertebrae; Time Factors | 2012 |
F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carmustine; Cell Survival; Cloning, Molecular; Cytoprotection; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Doxorubicin; Genetic Vectors; Hematopoietic Stem Cells; HL-60 Cells; Humans; K562 Cells; Lentivirus; Nimustine; Paclitaxel; Peptides; Real-Time Polymerase Chain Reaction; Temozolomide; Transgenes; Tumor Suppressor Proteins | 2012 |
Comparison of the clinical efficacy of temozolomide (TMZ) versus nimustine (ACNU)-based chemotherapy in newly diagnosed glioblastoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Karnofsky Performance Status; Male; Middle Aged; Nimustine; Survival Analysis; Temozolomide; Tumor Suppressor Proteins; Young Adult | 2014 |
Treatment results of glioblastoma during the last 30 years in a single institute.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Hospitals, University; Humans; Japan; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Neuronavigation; Nimustine; Prognosis; Retrospective Studies; Temozolomide; Treatment Outcome | 2013 |
Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Nucleus; Comet Assay; Dacarbazine; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Proteins; Nimustine; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Signal Transduction; Temozolomide; Up-Regulation | 2015 |
Proton beam therapy with concurrent chemotherapy for glioblastoma multiforme: comparison of nimustine hydrochloride and temozolomide.
Topics: Adult; Aged; Antineoplastic Agents; Dacarbazine; Female; Follow-Up Studies; Glioblastoma; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Nimustine; Proton Therapy; Retrospective Studies; Temozolomide; Treatment Outcome; Young Adult | 2016 |
Enhanced antitumor effects of radiotherapy combined local nimustine delivery rendezvousing with oral temozolomide chemotherapy in glioblastoma patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Combined Modality Therapy; Dacarbazine; Female; Follow-Up Studies; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nimustine; Proportional Hazards Models; Quality of Life; Radiotherapy; Temozolomide; Tomography, X-Ray Computed; Treatment Outcome | 2018 |
Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy.
Topics: Adult; Aged; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Drug Resistance; Drug Resistant Epilepsy; Female; Follow-Up Studies; Glioma; Humans; Levetiracetam; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Neurosurgical Procedures; Nimustine; Nitriles; Pyridones; Radiotherapy, Adjuvant; Receptors, AMPA; Retrospective Studies; Temozolomide; Young Adult | 2020 |
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Glioblastoma; Histones; Humans; Injections, Intraperitoneal; Lomustine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Nimustine; Salvage Therapy; Temozolomide; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2021 |