temozolomide has been researched along with methylnitronitrosoguanidine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Almassy, RJ; Boritzki, TJ; Calabrese, CR; Calvert, AH; Canan Koch, SS; Curtin, NJ; Ekker, A; Golding, BT; Griffin, RJ; Hostomsky, Z; Kumpf, RA; Kyle, S; Li, J; Maegley, KA; Mansour, RN; Newell, DR; Thomas, HD; Thoresen, LH; Tikhe, JG; Wang, LZ; Webber, SE; Yu, XH; Zhang, C; Zhang, KE; Zook, SE | 1 |
| Boulton, S; Durkacz, BW; Kyle, S | 1 |
| Berger, MS; Blank, A; Bobola, MS; Silber, JR; Tseng, SH | 1 |
| Arends, MJ; Clarke, AR; Dekker, M; Howard, LA; Kelly, J; Margison, GP; te Riele, H; Toft, NJ; Winton, DJ; Wyllie, AH | 1 |
| Allan, JM; Broekhof, JL; Carls, NH; Donker, I; Engelward, BP; Glassner, BJ; Hampson, RJ; Hersmus, R; Hickman, MJ; Hoeijmakers, JH; Roth, RB; Samson, LD; Warren, HB; Weeda, G; Wu, MM | 1 |
| Baumgartner, M; Kaina, B; Roos, W | 1 |
| Caldwell, D; Kelley, MR; Rinne, M | 1 |
| Fabian, K; Kaina, B; Thacker, J; Tsaryk, R | 1 |
| Batista, LF; Kaina, B; Menck, CF; Naumann, SC; Roos, WP; Weller, M; Wick, W | 1 |
| Briegert, M; Kaina, B | 1 |
| Bachoo, RM; Burma, S; Camacho, CV; Hahm, B; McEllin, B; Mukherjee, B; Tomimatsu, N | 1 |
| Dianov, GL; Digweed, M; Eich, M; Kaina, B; Roos, WP | 1 |
| Jin, YH; Liu, HY; Shu, F; Wang, QJ; Wang, Z; Yang, Y; Zhang, WB | 1 |
| Eich, M; Kaina, B; Nikolova, T; Roos, WP | 1 |
| Gupte, M; Sharma, VP; Tuck, AN; Williams, KJ | 1 |
15 other study(ies) available for temozolomide and methylnitronitrosoguanidine
| Article | Year |
|---|---|
Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: design, synthesis, and X-ray cocrystal structure.
Topics: Antineoplastic Agents; Crystallography, X-Ray; Dacarbazine; Drug Design; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Humans; Indoles; Isoquinolines; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship; Temozolomide; Topotecan; Tumor Cells, Cultured | 2002 |
Low nicotinamide mononucleotide adenylyltransferase activity in a tiazofurin-resistant cell line: effects on NAD metabolism and DNA repair.
Topics: Animals; Antineoplastic Agents; Carcinogens; Cell Division; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Leukemia L1210; Methylnitronitrosoguanidine; Mice; NAD; Nicotinamide-Nucleotide Adenylyltransferase; Ribavirin; Temozolomide | 1997 |
Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Guanine; Humans; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin; Temozolomide; Tumor Cells, Cultured | 1996 |
Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine.
Topics: Animals; Apoptosis; Cells, Cultured; Cisplatin; Dacarbazine; DNA Repair; DNA-Binding Proteins; Guanine; Intestinal Mucosa; Intestine, Small; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Mutagenesis; Mutagens; MutS Homolog 2 Protein; Proto-Oncogene Proteins; Stem Cells; Temozolomide | 1999 |
DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Carcinogens; Carmustine; Dacarbazine; Genotype; Hematopoietic System; Liver; Methylnitronitrosoguanidine; Mice; Mice, Knockout; Mitomycin; Models, Biological; O(6)-Methylguanine-DNA Methyltransferase; Streptozocin; Temozolomide | 1999 |
Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Division; Dacarbazine; DNA Damage; DNA Replication; fas Receptor; Gamma Rays; Gene Expression Regulation; Guanine; Humans; Lymphocytes; Methylnitronitrosoguanidine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Temozolomide; Tumor Suppressor Protein p53 | 2004 |
Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells.
Topics: Adenoviridae; Alkylating Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Dacarbazine; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Genetic Therapy; Genetic Vectors; Humans; Hydroxylamines; Immunohistochemistry; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Oligonucleotides; Sensitivity and Specificity; Sulfuric Acid Esters; Temozolomide; Time Factors | 2004 |
Xrcc2 deficiency sensitizes cells to apoptosis by MNNG and the alkylating anticancer drugs temozolomide, fotemustine and mafosfamide.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cisplatin; Cyclophosphamide; Dacarbazine; DNA-Binding Proteins; Humans; Methylnitronitrosoguanidine; Mitomycin; Mutagens; Nitrosourea Compounds; Organophosphorus Compounds; Temozolomide | 2006 |
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Brain Neoplasms; Caspases; Cell Cycle; Cell Proliferation; Dacarbazine; DNA Breaks, Double-Stranded; DNA Damage; Fas Ligand Protein; Fas-Associated Death Domain Protein; Flow Cytometry; Glioma; Guanine; Humans; Methylnitronitrosoguanidine; O(6)-Methylguanine-DNA Methyltransferase; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Temozolomide; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2007 |
Human monocytes, but not dendritic cells derived from them, are defective in base excision repair and hypersensitive to methylating agents.
Topics: Alkylating Agents; Cell Survival; Cells, Cultured; Dacarbazine; Dendritic Cells; DNA Methylation; DNA Repair; Drug Hypersensitivity; Humans; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Monocytes; Mutagens; Temozolomide | 2007 |
PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.
Topics: Animals; Antineoplastic Agents, Alkylating; Astrocytes; Benzimidazoles; Brain Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Dacarbazine; DNA Damage; DNA Repair; Glioblastoma; Methylnitronitrosoguanidine; Mice; Mice, Transgenic; Poly(ADP-ribose) Polymerase Inhibitors; PTEN Phosphohydrolase; Recombination, Genetic; Temozolomide | 2010 |
Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Caspase 7; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Dacarbazine; DNA Methylation; Drug Resistance, Neoplasm; Fibroblasts; Guanine; Homozygote; Humans; Melanoma; Methylnitronitrosoguanidine; Mutagens; Mutation; Necrosis; Nijmegen Breakage Syndrome; Nuclear Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Temozolomide; Uveal Neoplasms | 2010 |
Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioblastoma; Guanine; Humans; Mechanistic Target of Rapamycin Complex 1; Methylnitronitrosoguanidine; Multiprotein Complexes; Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Temozolomide; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2010 |
Contribution of ATM and ATR to the resistance of glioblastoma and malignant melanoma cells to the methylating anticancer drug temozolomide.
Topics: Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Dacarbazine; DNA Breaks, Double-Stranded; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Glioblastoma; Guanine; Humans; Melanoma; Methylnitronitrosoguanidine; Phosphorylation; Protein Kinases; Signal Transduction; Temozolomide; Tumor Suppressor Proteins | 2013 |
Major differences between tumor and normal human cell fates after exposure to chemotherapeutic monofunctional alkylator.
Topics: Antineoplastic Agents, Alkylating; Apoptosis Inducing Factor; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Lineage; Dacarbazine; Electrophoretic Mobility Shift Assay; Fluorescent Antibody Technique, Indirect; Humans; Methylnitronitrosoguanidine; Neoplasm Proteins; Neoplasms; Temozolomide | 2013 |