temozolomide has been researched along with methotrexate in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 21 (63.64) | 24.3611 |
| 2020's | 4 (12.12) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dello Russo, C; Graziani, G; Navarra, P; Tentori, L; Tringali, G; Vairano, M | 1 |
| Abrey, LE; DeAngelis, LM; Demopoulos, A; Enting, RH | 1 |
| Dichgans, J; Hebart, H; Herrlinger, U; Kanz, L; Weller, M | 1 |
| Leenstra, S; Majoie, CB; Richel, DJ; Terheggen, F; Troost, D | 1 |
| Barrie, M; Carnin, C; Chinot, O; Hoang-Xuan, K; Omuro, AM; Taillandier, L | 1 |
| Estlin, EJ; McGown, A; Najim, N; Podmore, ID | 1 |
| Yamanaka, R | 1 |
| Cheung, T; Fraser, JA; Proulx, A | 1 |
| Behler, CM; Cha, S; Damon, LE; Hwang, J; Issa, S; McDermott, M; O'Brien, J; Rubenstein, JL; Shuman, MA; Treseler, P; Valles, F; Wieduwilt, MJ | 1 |
| Falchi, L; Ferranti, L; Gunnellini, M; Liberati, AM | 1 |
| Dhamija, R; Nelson, A; Nickels, K | 1 |
| Bachour, M; Hussein, T; Kenj, M; Salamoon, M | 1 |
| Bai, B; Cai, QC; Cai, QQ; Gao, Y; Huang, HQ; Jiang, WQ; Wang, XX; Xia, YF; Xia, ZJ | 1 |
| Bird, TG; Child, F; Morris, SL; Wain, EM; Whittaker, S | 1 |
| Barrié, M; Benouaich-Amiel, A; Chinot, O; Choquet, S; del Rio, MS; Delgadillo, D; Delwail, V; Ghesquieres, H; Gonzalez-Aguilar, A; Gressin, R; Gyan, E; Hoang-Xuan, K; Houillier, C; Huchet, A; Lacomblez, L; Lamy, T; Lebouvier-Sadot, S; Omuro, A; Soubeyran, P; Soussain, C; Taillandier, L; Tanguy, ML; Touitou, V | 1 |
| Augspurger, M; Bartlett, NL; Bokstein, F; Bovi, JA; Brat, D; Fisher, BJ; Glass, J; Liepman, MK; Mehta, MP; Schultz, CJ; Solhjem, MC; Suh, JH; Werner-Wasik, M; Won, M | 1 |
| Bodaghi, B; Cassoux, N; Choquet, S; Costopoulos, M; Hoang-Xuan, K; Houillier, C; Le Cossec, C; Legarf-Tavernier, M; LeHoang, P; Nguyen, DT; Omuro, A; Soussain, C; Touitou, V | 1 |
| Armand, P; Batchelor, TT; Chen, YB; DeFilipp, Z; El-Jawahri, A; Li, S; Nayak, L; Wang, N | 1 |
| Liu, Y | 1 |
| Jin, J; Mao, L; Wang, H; Wang, L; Wang, M; Wei, J | 1 |
| Bi, X; Chen, C; Chen, H; Cui, J; Jiang, W; Li, ZM; Liu, P; Nie, M; Sun, P; Wang, Y; Xia, Y; Yan, S; Yang, H; Zhang, XW | 1 |
| Brenner, A; Butler, MJ; Faivre, G; Le, I | 1 |
| Baehring, JM; Kaulen, LD | 1 |
| Abe, K; Arakawa, Y; Asai, A; Asano, K; Fukuda, H; Gomyo, M; Katayama, H; Kinoshita, M; Koga, T; Kojima, M; Mishima, K; Mizusawa, J; Momii, Y; Nagane, M; Nakamura, S; Narita, Y; Natsumeda, M; Nishikawa, R; Sasaki, A; Sasaki, H; Sasaki, N; Sasayama, T; Shibahara, I; Shinojima, N; Sumi, M; Tamaru, JI; Tsuchiya, K; Tsurubuchi, T; Yamasaki, F; Yoshimoto, K | 1 |
| Bromberg, JEC; Doorduijn, JK | 1 |
| Agrawal, P; Bachanova, V; Berg, S; Bond, DA; Cai, J; Carter, J; Chang, J; Cleveland, J; David, KA; Epperla, N; Evens, AM; Folstad, M; Glantz, M; Goldlust, SA; Graber, J; Habib, A; Hossain, N; Kahl, B; Karmali, R; Kim, MS; Kim, SH; Kumar, P; Lin, Y; Major, A; Malecek, MK; Martin, P; Mier-Hicks, A; Naik, S; Ney, D; Ollila, TA; Rajakumar, P; Reddy, N; Rubenstein, J; Salman, S; Sieg, A; Singer, S; Smith, SM; Spurgeon, S; Strouse, C; Sundaram, S; Torka, P; Tsang, M; Vaca, R; Vendiola, JA; Venugopal, P; Zayac, A | 1 |
5 review(s) available for temozolomide and methotrexate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Agents, Alkylating; Brain Neoplasms; Central Nervous System Neoplasms; Cohort Studies; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Drug Evaluation; Drug Resistance, Neoplasm; Eye Neoplasms; Female; Humans; Immunotherapy; Life Tables; Lymphoma, B-Cell; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Retrospective Studies; Rituximab; Salvage Therapy; Survival Analysis; Temozolomide; Treatment Outcome | 2004 |
[Medical management of primary central nervous system lymphoma refractory or resistant to standard of care treatment].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dacarbazine; Drug Discovery; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Methotrexate; Neoplasm Recurrence, Local; Rituximab; Salvage Therapy; Temozolomide; Topotecan | 2009 |
Leptomeningeal carcinomatosis from gastric cancer successfully treated by the intrathecal methotrexate plus temozolomide and simultaneous radiotherapy: Case report and literatures review.
Topics: Abdominal Pain; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Chemoradiotherapy, Adjuvant; Dacarbazine; Gastroscopy; Humans; Injections, Spinal; Male; Meningeal Carcinomatosis; Methotrexate; Middle Aged; Pylorus; Stomach Neoplasms; Temozolomide; Treatment Outcome | 2017 |
Treatment Options for Recurrent Primary CNS Lymphoma.
Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Busulfan; Central Nervous System Neoplasms; Cranial Irradiation; Cyclophosphamide; Cytarabine; Humans; Immune Checkpoint Inhibitors; Lenalidomide; Lymphoma, Non-Hodgkin; Methotrexate; Nivolumab; Pemetrexed; Procarbazine; Prospective Studies; Receptors, Chimeric Antigen; Retrospective Studies; Rituximab; Temozolomide; Thiotepa; Vincristine | 2022 |
6 trial(s) available for temozolomide and methotrexate
| Article | Year |
|---|---|
Temozolomide and methotrexate for primary central nervous system lymphoma in the elderly.
Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Dacarbazine; Drug Administration Schedule; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Retrospective Studies; Temozolomide; Treatment Outcome | 2007 |
Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Consolidation Chemotherapy; Cytarabine; Dacarbazine; Diffusion Magnetic Resonance Imaging; Etoposide; Female; Humans; Immunotherapy; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Remission Induction; Rituximab; Survival Analysis; Temozolomide; Treatment Outcome | 2012 |
Methotrexate and temozolomide versus methotrexate, procarbazine, vincristine, and cytarabine for primary CNS lymphoma in an elderly population: an intergroup ANOCEF-GOELAMS randomised phase 2 trial.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Disease-Free Survival; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Procarbazine; Prospective Studies; Quality of Life; Temozolomide; Treatment Outcome; Vincristine | 2015 |
Phase I and II Study of Induction Chemotherapy With Methotrexate, Rituximab, and Temozolomide, Followed By Whole-Brain Radiotherapy and Postirradiation Temozolomide for Primary CNS Lymphoma: NRG Oncology RTOG 0227.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Dacarbazine; Disease-Free Survival; Female; Humans; Induction Chemotherapy; Lymphoma; Male; Methotrexate; Middle Aged; Rituximab; Temozolomide; Whole-Body Irradiation; Young Adult | 2016 |
Primary Oculocerebral Lymphoma: MTX Polychemotherapy Alone on Intraocular Disease Control.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cerebellum; Cytarabine; Dacarbazine; Eye Neoplasms; Female; Humans; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Procarbazine; Survival Analysis; Temozolomide; Vincristine | 2016 |
Randomized phase III study of high-dose methotrexate and whole-brain radiotherapy with/without temozolomide for newly diagnosed primary CNS lymphoma: JCOG1114C.
Topics: Antineoplastic Agents, Alkylating; Brain; Central Nervous System Neoplasms; Disease-Free Survival; Humans; Lymphoma; Methotrexate; Temozolomide | 2023 |
22 other study(ies) available for temozolomide and methotrexate
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Primary cultures of microglial cells for testing toxicity of anticancer drugs.
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Culture Techniques; Cell Survival; Dacarbazine; Drug Screening Assays, Antitumor; Humans; Lipopolysaccharides; Methotrexate; Microglia; Nervous System Diseases; Rats; Rats, Wistar; Temozolomide; Toxicity Tests | 2004 |
Relapse of primary CNS lymphoma after more than 10 years in complete remission.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dacarbazine; Humans; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasm Recurrence, Local; Procarbazine; Temozolomide; Vincristine | 2005 |
Local recurrence and distant metastasis of supratentorial primitive neuro-ectodermal tumor in an adult patient successfully treated with intensive induction chemotherapy and maintenance temozolomide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Cyclophosphamide; Dacarbazine; Doxorubicin; Humans; Liver Neoplasms; Male; Methotrexate; Neoplasm Recurrence, Local; Neuroectodermal Tumors, Primitive; Prednisone; Remission Induction; Supratentorial Neoplasms; Temozolomide; Treatment Outcome; Vincristine | 2007 |
Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Proliferation; Cerebellar Neoplasms; Cisplatin; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Fluorometry; Glioma; Glutathione; Humans; Medulloblastoma; Methionine; Methotrexate; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2009 |
Primary central nervous system lymphoma presenting as Parinaud syndrome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cranial Irradiation; Dacarbazine; Diagnosis, Differential; Diplopia; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Ocular Motility Disorders; Spinal Puncture; Temozolomide; Tomography, X-Ray Computed | 2011 |
High-dose methotrexate and temozolomide associated with intrathecal liposomal cytarabine for the treatment of primary or secondary central nervous system lymphoma: a preliminary experience.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Nervous System; Temozolomide | 2012 |
Posttransplant lymphoproliferative disorder in an 11-year-old immunosuppressed boy.
Topics: Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain; Child; Dacarbazine; Heart Transplantation; Humans; Hypesthesia; Immunosuppression Therapy; Lymphoproliferative Disorders; Magnetic Resonance Imaging; Male; Methotrexate; Muscle Weakness; Rituximab; Temozolomide | 2013 |
High-dose methotrexate, high-dose cytarabine and temozolomide for the treatment of primary central nervous system lymphoma (PCNSL).
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Disease-Free Survival; Female; Humans; Male; Methotrexate; Middle Aged; Survival Rate; Temozolomide; Young Adult | 2013 |
Clinical outcomes of patients with newly diagnosed primary central nervous system lymphoma are comparable on treatment with high-dose methotrexate plus temozolomide and with high-dose methotrexate plus cytarabine: a single-institution experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neutropenia; Remission Induction; Temozolomide; Thrombocytopenia; Treatment Outcome; Young Adult | 2014 |
Temozolomide for central nervous system involvement in mycosis fungoides.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Dacarbazine; Dexamethasone; Female; Humans; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Retreatment; Skin Neoplasms; Temozolomide; Treatment Outcome | 2016 |
High-dose chemotherapy with thiotepa, busulfan, and cyclophosphamide and autologous stem cell transplantation for patients with primary central nervous system lymphoma in first complete remission.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Busulfan; Central Nervous System Neoplasms; Cyclophosphamide; Cytarabine; Dacarbazine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lymphoma; Male; Methotrexate; Middle Aged; Mucositis; Remission Induction; Retrospective Studies; Rituximab; Stem Cell Transplantation; Temozolomide; Thiotepa; Transplantation Conditioning; Transplantation, Autologous | 2017 |
Primary central nervous system lymphoma: Retrospective analysis of 34 cases in a single centre.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Drug Dosage Calculations; Female; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Retrospective Studies; Rituximab; Survival Analysis; Temozolomide; Vincristine | 2018 |
High-dose Methotrexate plus temozolomide with or without rituximab in patients with untreated primary central nervous system lymphoma: A retrospective study from China.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Female; Humans; Induction Chemotherapy; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Multivariate Analysis; Retrospective Studies; Rituximab; Survival Analysis; Temozolomide; Treatment Outcome | 2019 |
Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma.
Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Central Nervous System Neoplasms; Drug Therapy, Combination; Female; Humans; Lymphoma, Non-Hodgkin; Maintenance Chemotherapy; Male; Methotrexate; Middle Aged; Neutropenia; Procarbazine; Progression-Free Survival; Rituximab; Temozolomide; Vincristine | 2019 |
Is there a future for maintenance temozolomide chemotherapy in PCNSL?
Topics: Brain; Dacarbazine; Humans; Lymphoma; Methotrexate; Temozolomide | 2023 |
Older patients with primary central nervous system lymphoma: Survival and prognostication across 20 U.S. cancer centers.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Lymphoma; Methotrexate; Middle Aged; Retrospective Studies; Rituximab; Temozolomide | 2023 |