Page last updated: 2024-08-16

temozolomide and lomustine

temozolomide has been researched along with lomustine in 97 studies

Research

Studies (97)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (2.06)	18.2507
2000's	27 (27.84)	29.6817
2010's	41 (42.27)	24.3611
2020's	27 (27.84)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Han, KL; Jia, Y; Li, P; Qiao, Y; Zhang, MM	1
Baer, JC; Freeman, AA; Margison, GP; Newlands, ES; Rafferty, JA; Watson, AJ	1
Darling, JL; Sankar, A; Thomas, DG	1
Chinot, O	1
Bardenheuer, W; Flasshove, M; Jansen, M; Moritz, T; Seeber, S; Sorg, UR	1
Croteau, D; Mikkelsen, T	1
Basso, U; Berti, F; Brandes, AA; Ermani, M; Gardiman, M; Monfardini, S; Pinna, G; Rotilio, A; Scienza, R; Vastola, F	1
Baayen, HC; Barkhof, F; Boogerd, W; Castelijns, JA; Elkhuizen, PH; Heimans, JJ; Postma, TJ; Uitdehaag, BM; Vos, MJ	1
Baron, B; Boogerd, W; Bravo Marques, J; Chinot, O; De Beule, N; Kros, JM; Taphoorn, MJ; van den Bent, MJ; van der Rijt, CC; Vecht, CJ	1
Engelhard, HH; Mundt, A; Stelea, A	1
Bourg, V; Chanalet, S; Chatel, M; Fontaine, D; Frenay, M; Lebrun, C; Lonjon, M; Michiels, JF; Paquis, P; Ramaioli, A; Vandenbos, F	1
Chamberlain, MC	2
Carpentier, A; Cartalat-Carel, S; Chinot, O; Cougnard, J; Delattre, JY; Djafari, L; Duffau, H; Gervais, H; Hoang-Xuan, K; Honnorat, J; Laigle, F; Mokhtari, K; Napolitano, M; Sanson, M; Taillandier, L; Taillibert, S	1
de Bruin, HG; de Wit, MC; Eijkenboom, W; Sillevis Smitt, PA; van den Bent, MJ	1
Allgeier, A; Brandes, AA; Enting, RH; Frenay, M; Kros, JM; Menten, J; Stege, EB; Taphoorn, MJ; Tosoni, A; Triebels, VH; van den Bent, MJ; van Heuvel, I	1
Comella, P; Formato, R; Iaffaioli, RV; Muto, P; Pisano, A; Quattrin, S; Tafuto, S; Tortoriello, A	1
Brandes, AA; Ermani, M; Gardiman, M; Ghimenton, C; Iuzzolino, P; Nicolardi, L; Reni, M; Rotilio, A; Sotti, G; Tosoni, A	1
Landi, A; Piccirilli, M; Salvati, M	1
Bamberg, M; Blaschke, B; Herrlinger, U; Hundsberger, T; Koch, D; Kortmann, RD; Loeser, S; Meyermann, R; Reifenberger, G; Rieger, J; Sommer, C; Steinbach, JP; Tan, TC; Weller, M; Wick, W	1
Mabasa, VH; Taylor, SC	1
Bate, SC; Beirne, DA; Eisen, TG; Gibbens, IM; Gore, ME; Hughes, SA; Larkin, JM; Patel, PM; Thomas, K	1
Choi, JD; Friedman, AH; Powers, CJ; Sampson, JH; Vredenburgh, JJ	1
Adamson, PC; Blaney, SM; Flom, L; Ingle, AM; Jakacki, RI; Pollack, IF; Prados, MD; Timmerman, R; Yates, A; Zhou, T	1
Ashley, DM; Dobrovic, A; Drummond, KJ; Friedman, HS; Gan, HK; Hawkins, CJ; Johns, TG; Kaye, AH; Lovric, MM; Maxwell, JA; Mikeska, T; Riffkin, CD	1
Baumert, BG; Stupp, R	1
Bähr, O; Glas, M; Happold, C; Herrlinger, U; Kortmann, RD; Reifenberger, G; Rieger, J; Steinbach, JP; Weller, M; Wick, W; Wiewrodt, D	1
Konishi, N; Nakamura, M; Nakase, H; Shimada, K	1
Nishikawa, R	1
DeAngelis, LM	1
Bamberg, M; Engel, C; Ernemann, U; Felsberg, J; Hartmann, C; Ketter, R; Koeppen, S; Kortmann, RD; Meisner, C; Meyermann, R; Pietsch, T; Rapp, M; Reifenberger, G; Sabel, MC; Stockhammer, F; Stoffels, M; von Deimling, A; Weller, M; Wick, W; Wiestler, OD	1
Delashaw, JB; Doolittle, ND; Gahramanov, S; Guillaume, DJ; Hedrick, NA; Neuwelt, EA	1
Agha, CA; Elias, DA; Fathallah-Shaykh, HM; Hassan, A; Ibrahim, S	1
Bekele, BN; Bobustuc, GC; Colman, H; Conrad, CA; Gilbert, MR; Groves, MD; Hsu, SH; Levin, VA; Puduvalli, VK; Qiao, W; Walbert, T; Yung, WK	1
Kim, JH; Kim, ST; Kim, WS; Kong, DS; Kwon, KH; Lee, JI; Lim, DH; Nam, DH; Park, K; Suh, YL	1
Arnold, L; Faoro, D; Gerber, NU; Grotzer, MA; Haybaeck, J; Hegi, M; Hürlimann, ML; Mittelbronn, M; Rutkowski, S; Sciuscio, D; Shalaby, T; von Bueren, AO	1
Beall, S; Brada, M; Collins, VP; Erridge, S; Gabe, R; Gattamaneni, R; Hopkins, K; Lee, SM; Levy, D; Rampling, R; Saran, F; Stenning, S; Thompson, LC	1
Abrey, LE; Aldape, KD; Ashby, LS; Cairncross, JG; Chamberlain, MC; Cloughesy, TF; DeAngelis, LM; Eichler, AF; Fisher, BJ; Green, RM; Iwamoto, FM; Jhanwar, SC; Kamar, FG; Lassman, AB; Ligon, KL; Louis, DN; Mason, WP; Paleologos, NA; Panageas, KS; Rivera, AL; Robins, HI; Rocque, BG; Roldán, GB; Rosenblum, MK; Schiff, D; Weaver, SA; Wen, PY	1
Ivanov, VG; Korytova, LI; Masliukova, EA; Meshechkin, AV; Zhabuna, RM	1
Audrain, O; Carsin, B; Gedouin, D; Hamlat, A; Lecouillard, I; Lesimple, T; Louvel, G; Mesbah, H; Quillien, V; Riffaud, L; Vauleon, E	1
Filss, C; Glas, M; Hadizadeh, DR; Herrlinger, U; Kuchelmeister, K; Langen, KJ; Mack, F; Pietsch, T; Schäfer, N; Schüller, H; Scorzin, J; Simon, M; Stuplich, M; Urbach, H	1
Ducray, F; Lekoubou, A; Viaccoz, A	1
Brada, M; Chan, R; Collins, VP; Di, Y; Gabe, R; Ichimura, K; Pearson, D; Stenning, SP; Thompson, LC	1
Chapet, S; Lévy, S; Mazeron, JJ	1
Ameratunga, MS; Grant, R; Khasraw, M; Pavlakis, N; Wheeler, H	1
Lok, E; Swanson, KD; Wong, ET	1
Schiff, D	1
Levin, VA	1
Rinne, ML; Wen, PY	1
Du Four, S; Duerinck, J; Everaert, H; Hau, P; Michotte, A; Neyns, B; Sander, W; Van Binst, AM	1
Lassman, AB	1
Akalan, N; Akyuz, C; Cengiz, M; Eren, G; Gurkaynak, M; Ozyigit, G; Varan, A; Yazici, G; Yüce, D; Zorlu, F	1
Abuali, I; Grossman, SA; Lu, Y; Strowd, RE; Ye, X	1
Bartolotti, M; Brandes, AA; Franceschi, E; Tosoni, A	1
Brat, DJ; Burger, PC; Buxton, A; Cohen, KJ; Eckel, SP; Hamilton, RL; Jakacki, RI; Krailo, MD; Lavey, RS; Pollack, IF; Rosenblum, MK; Zhou, T	1
Felsberg, J; Gramatzki, D; Hentschel, B; Hofer, S; Krex, D; Reifenberger, G; Roth, P; Rushing, EJ; Schnell, O; Simon, M; Weller, M; Westphal, M; Wick, W	1
Guo, J; Parasramka, S; Rosenfeld, M; Talari, G; Villano, JL	1
Buslei, R; Distel, L; Fietkau, R; Putz, F; Stritzelberger, J	1
Wick, W; Winkler, F	1
Ewald, C; Grube, S; Kalff, R; Kögler, C; Lawson McLean, A; Walter, J	1
Castro-Martinez, E; Gonzalez-Aguilar, A; Guerrero-Juarez, V; Gutierrez-Aceves, A; Hernandez-Hernandez, A; Lopez-Martinez, M; Peiro-Osuna, RP; Reyes-Moreno, I; Santos-Zambrano, J	1
Ameratunga, M; Grant, R; Khasraw, M; Pavlakis, N; Simes, J; Wheeler, H	1
Hegi, ME; Lukas, RV; Stupp, R	1
Killock, D	1
Bobiak, S; Dastani, H; Kim Le, T; Korytowsky, B; Norden, AD; Singh, P; You, M	1
Kortmann, RD; Seidel, C	1
Hernberg, M; Kohtamäki, L; Koivunen, J; Mäkelä, S; Mattila, KE; Ramadan, S; Skyttä, T; Tiainen, L; Tyynelä-Korhonen, K; Vihinen, P; Vuoristo, MS	1
Atkins, KM; Dietrich, J; Loeffler, JS; McDuff, SGR; Oh, KS; Shih, HA	1
Liaquat, I; Martin, AJ; Mukherjee, S; Stapleton, SR; Wood, J	1
Ansell, P; Brilhante, J; Chinot, O; Clement, PM; Coens, C; De Vos, F; Dey, J; Dubbink, HJ; Eoli, M; Franceschi, E; French, P; Frenel, JS; Golfinopoulos, V; Gorlia, T; Krause, S; Looman, J; Nuyens, S; Sanghera, P; Sepulveda, JM; Smits, M; Spruyt, M; Van Den Bent, M; Walenkamp, A; Weller, M; Whenham, N	1
Blau, T; Deuschl, C; Glas, M; Herrlinger, U; Kebir, S; Keyvani, K; Kleinschnitz, C; Lazaridis, L; Oster, C; Pierscianek, D; Schäfer, N; Scheffler, B; Schmidt, T; Stuschke, M; Sure, U; Teuber-Hanselmann, S; Tzaridis, T; Weller, J	1
Lobbous, M; Nabors, LB	1
Rudà, R; Soffietti, R; Touat, M	1
Coch, C; Felsberg, J; Fimmers, R; Glas, M; Goldbrunner, R; Grauer, O; Hau, P; Herrlinger, U; Kebir, S; Krex, D; Pietsch, T; Reifenberger, G; Sabel, M; Schäfer, N; Schaub, C; Schlegel, U; Schneider, M; Seidel, C; Seidel, S; Steinbach, JP; Tonn, JC; Tzaridis, T; Vatter, H; Weller, J	1
Accomando, W; Bettegowda, C; Bota, D; Brem, S; Butowski, N; Cachia, D; Chen, CC; Cloughesy, TF; Damek, D; Elder, B; Gruber, H; Hogan, D; Iwamoto, F; Kabbinavar, F; Kaptain, G; Kheoh, T; Kim, L; Landolfi, J; Montellano, TT; Moshel, Y; Ostertag, D; Perry, J; Petrecca, K; Piccioni, D; Placantonakis, D; Rao, AR; Salacz, M; Vogelbaum, MA; Walbert, T; Zhu, JJ	1
Bronniman, C; Carpentier, C; Ciron, DL; Dehais, C; Ducray, F; Esteyrie, V; Figarella-Branger, D; Martin, E; Moyal, EC; Network, P; Pouessel, D; Uro-Coste, E	1
Egensperger, R; Karschnia, P; Katzendobler, S; Lietke, S; Suchorska, B; Thon, N; Tonn, JC; Weller, J; Weller, M	1
Bauer, EK; Baues, C; Ceccon, G; Celik, E; Fink, GR; Galldiks, N; Gielen, GH; Herrlinger, U; Kabbasch, C; Langen, KJ; Lohmann, P; Marnitz, S; Schäfer, N; Schaub, C; Stoffels, G; Tscherpel, C; Weller, J; Werner, JM	1
Agarwal, A; Alam, A; Basu, S; Behura, L; Castro, M; Choudhary, NR; G, P; Joseph, V; Kapoor, S; Kulkarni, S; Lala, DA; Nair, P; Pampana, A; Parashar, R; Prakash, A; Rajagopalan, S; Roy, KGG	1
Fujii, T; Ichimura, K; Kawauchi, D; Kobayashi, T; Kondo, A; Nakano, T; Narita, Y; Sasaki, N; Satomi, K; Takahashi, M; Tomiyama, A; Uchida, E; Wada, K; Yamamuro, S; Yoshino, A	1
Jaal, J; Laasfeld, T; Lavogina, D; Lust, H; Vardja, M	1
Aichholzer, M; Berghoff, AS; Dieckmann, K; Furtner, J; Goldberger, S; Hatziioannou, T; Heller, G; Leibetseder, A; Mair, MJ; Pichler, J; Preusser, M; Puhr, R; Tomasich, E; von Oertzen, T; Weis, S; Widhalm, G; Wöhrer, A	1
Beltzig, L; Christmann, M; Kaina, B	1
Aquilanti, E; Wen, PY	1
Jang, BS; Kim, IA; Park, AJ	1
Awortwe, C; Cascorbi, I; Kaehler, M; Majchrzak-Celińska, A; Nagel, I; Radtke, L; Sebens, S; Vater, I	1
Brehmer, S; Bullinger, L; Giordano, FA; Glas, M; Goldbrunner, R; Grauer, O; Hau, P; Herrlinger, U; Kowalski, T; Krex, D; Potthoff, AL; Ringel, F; Sabel, M; Schäfer, N; Schaub, C; Schmidt-Graf, F; Schneider, M; Schnell, O; Seidel, C; Steinbach, JP; Tabatabai, G; Tonn, JC; Tzaridis, T; Vajkoczy, P; Vatter, H; Weller, J; Zeiner, PS; Zeyen, T	1
Chang, SM; Cloughesy, TF; de Groot, JF; Ellingson, BM; Galanis, E; Gilbert, MR; Kim, J; Lassman, AB; Li, G; Li, S; van den Bent, M; Vogelbaum, MA; Weller, M; Wen, PY; Wick, W; Youssef, G	1
Heydarzadeh, S; Iqbal, MZ; Kong, X; Nozhat, Z; Shahriari-Khalaji, M; Wang, S	1
Dor-On, E; Fishman, H; Giladi, M; Haber, A; Kinzel, A; Monin, R; Palti, Y; Weinberg, U	1
Fuchs, D; Morandi, L; Nytko, KJ; Rohrer Bley, C; Tonon, C; Weyland, MS	1
Duffy, C; Galldiks, N; Glas, M; Goldbrunner, R; Grauer, O; Hattingen, E; Hau, P; Herrlinger, U; Krex, D; Nitsch, L; Paech, D; Potthoff, AL; Radbruch, A; Schäfer, N; Schaub, C; Schlegel, U; Schneider, M; Seidel, C; Steinbach, JP; Stummer, W; Tabatabai, G; Tzaridis, T; Weller, J; Zeiner, PS; Zeyen, T	1

Reviews

19 review(s) available for temozolomide and lomustine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Chemotherapy for the treatment of oligodendroglial tumors. Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; Lomustine; Oligodendroglioma; Procarbazine; Prognosis; Temozolomide; Vincristine	2001
Adults with newly diagnosed high-grade gliomas. Current treatment options in oncology, 2001, Volume: 2, Issue:6 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Contraindications; Cranial Irradiation; Craniotomy; Dacarbazine; Disease Progression; Epidemiologic Methods; Glioblastoma; Humans; Isotretinoin; Lomustine; Palliative Care; Procarbazine; Radiosurgery; Radiotherapy, Adjuvant; Radiotherapy, Conformal; Temozolomide; Treatment Outcome; Vincristine	2001
Oligodendroglioma and anaplastic oligodendroglioma: clinical features, treatment, and prognosis. Surgical neurology, 2003, Volume: 60, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Diagnosis, Differential; Humans; Incidence; Lomustine; Oligodendroglioma; Procarbazine; Prognosis; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors; Temozolomide; Tomography, Emission-Computed; Tomography, X-Ray Computed; Vincristine	2003
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression. Neurology, 2004, Aug-10, Volume: 63, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Cohort Studies; Combined Modality Therapy; Contrast Media; Cranial Irradiation; Dacarbazine; Dexamethasone; Diagnosis, Differential; Disease Progression; Female; Follow-Up Studies; Gadolinium; Glioma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Selection; Procarbazine; Temozolomide; Vincristine	2004
[Clinicopathological diagnosis of gliomas by genotype analysis]. Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Genotype; Glioblastoma; Humans; Lomustine; Loss of Heterozygosity; Molecular Diagnostic Techniques; Pharmacogenetics; Procarbazine; Prognosis; Temozolomide; Tumor Suppressor Proteins; Vincristine	2009
[Treatment of glioma with temozolomide]. Brain and nerve = Shinkei kenkyu no shinpo, 2009, Volume: 61, Issue:7 Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Dacarbazine; DNA Damage; Glioblastoma; Humans; Leukemia, Myeloid, Acute; Lomustine; Myelodysplastic Syndromes; Neoplasms, Second Primary; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide	2009
Chemotherapy in low-grade gliomas. Current opinion in oncology, 2012, Volume: 24, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Clinical Trials as Topic; Dacarbazine; Glioma; Humans; Lomustine; Procarbazine; Temozolomide; Treatment Outcome; Vincristine	2012
[Management of gliomas]. Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6 Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Chromosome Deletion; Chromosomes, Human, Pair 1; Clinical Trials as Topic; Combined Modality Therapy; Dacarbazine; Dose Fractionation, Radiation; Drug Resistance, Neoplasm; Glioma; Humans; Lomustine; Methylation; Multicenter Studies as Topic; Neoplasm Proteins; Neurosurgical Procedures; O(6)-Methylguanine-DNA Methyltransferase; Procarbazine; Radiotherapy Dosage; Radiotherapy, Intensity-Modulated; Temozolomide; Treatment Outcome; Vincristine	2014
Antiangiogenic therapy for high-grade glioma. The Cochrane database of systematic reviews, 2014, Sep-22, Issue:9 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; Dacarbazine; Glioblastoma; Humans; Hypertension; Irinotecan; Lomustine; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Proteinuria; Randomized Controlled Trials as Topic; Snake Venoms; Temozolomide	2014
Low-grade gliomas. Continuum (Minneapolis, Minn.), 2015, Volume: 21, Issue:2 Neuro-on Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression; Glioma; Humans; Isocitrate Dehydrogenase; Lomustine; Mutation; Procarbazine; Temozolomide; Treatment Outcome; Vincristine	2015
Procarbazine, lomustine and vincristine or temozolomide: which is the better regimen? CNS oncology, 2015, Volume: 4, Issue:5 Topics: Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Dacarbazine; Humans; Lomustine; Oligodendroglioma; Procarbazine; Temozolomide; Treatment Outcome; Vincristine	2015
Nitrosoureas in the Management of Malignant Gliomas. Current neurology and neuroscience reports, 2016, Volume: 16, Issue:2 Topics: Dacarbazine; Glioma; Humans; Lomustine; Nitrosourea Compounds; Organophosphorus Compounds; Procarbazine; Temozolomide; Vincristine	2016
Procarbazine, lomustine and vincristine for recurrent high-grade glioma. The Cochrane database of systematic reviews, 2017, 07-26, Volume: 7 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Dacarbazine; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Glioma; Humans; Hydroxyurea; Lomustine; Methylprednisolone; Middle Aged; Neoplasm Recurrence, Local; Procarbazine; Randomized Controlled Trials as Topic; Temozolomide; Vincristine	2017
Anti-angiogenic therapy for high-grade glioma. The Cochrane database of systematic reviews, 2018, 11-22, Volume: 11 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Camptothecin; Dacarbazine; Glioblastoma; Humans; Hypertension; Irinotecan; Lomustine; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Progression-Free Survival; Proteinuria; Randomized Controlled Trials as Topic; Snake Venoms; Temozolomide	2018
Radiation and chemotherapy for high-risk lower grade gliomas: Choosing between temozolomide and PCV. Cancer medicine, 2020, Volume: 9, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Glioma; Humans; Isocitrate Dehydrogenase; Lomustine; Mutation; Neoplasm Grading; Procarbazine; Progression-Free Survival; Randomized Controlled Trials as Topic; Temozolomide; Vincristine	2020
Is chemotherapy alone an option as initial treatment for low-grade oligodendrogliomas? Current opinion in neurology, 2020, Volume: 33, Issue:6 Topics: Antineoplastic Agents; Brain Neoplasms; Humans; Lomustine; Oligodendroglioma; Temozolomide; Treatment Outcome; Vincristine	2020
Objective response rate targets for recurrent glioblastoma clinical trials based on the historic association between objective response rate and median overall survival. Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Humans; Lomustine; Neoplasm Recurrence, Local; Temozolomide	2023
Advanced biomaterials for human glioblastoma multiforme (GBM) drug delivery. Biomaterials science, 2023, Jun-13, Volume: 11, Issue:12 Topics: Antineoplastic Agents; Bevacizumab; Glioblastoma; Humans; Lomustine; Temozolomide	2023

Trials

21 trial(s) available for temozolomide and lomustine

Article	Year
A prospective study on glioblastoma in the elderly. Cancer, 2003, Feb-01, Volume: 97, Issue:3 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Lomustine; Male; Neurosurgical Procedures; Procarbazine; Prospective Studies; Radiotherapy Dosage; Survival Analysis; Temozolomide; Vincristine	2003
Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972. Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:4 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Oligodendroglioma; Procarbazine; Temozolomide; Treatment Outcome; Vincristine	2003
Initial chemotherapy in gliomatosis cerebri. Neurology, 2004, Jul-27, Volume: 63, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Karnofsky Performance Status; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasms, Neuroepithelial; Oligodendroglioma; Procarbazine; Survival Analysis; Temozolomide; Treatment Outcome; Vincristine	2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression. Neurology, 2004, Aug-10, Volume: 63, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Cohort Studies; Combined Modality Therapy; Contrast Media; Cranial Irradiation; Dacarbazine; Dexamethasone; Diagnosis, Differential; Disease Progression; Female; Follow-Up Studies; Gadolinium; Glioma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Selection; Procarbazine; Temozolomide; Vincristine	2004
Salvage PCV chemotherapy for temozolomide-resistant oligodendrogliomas. Neurology, 2004, Sep-14, Volume: 63, Issue:5 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Cohort Studies; Dacarbazine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Lomustine; Male; Middle Aged; Oligodendroglioma; Procarbazine; Remission Induction; Retrospective Studies; Salvage Therapy; Sequence Deletion; Temozolomide; Treatment Outcome; Vincristine	2004
Phase I study of temozolomide and lomustine in the treatment of high grade malignant glioma. Frontiers in bioscience : a journal and virtual library, 2006, Jan-01, Volume: 11 Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cohort Studies; Dacarbazine; Dose-Response Relationship, Drug; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Temozolomide; Time Factors	2006
Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Sep-20, Volume: 24, Issue:27 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease-Free Survival; DNA Methylation; Drug Administration Schedule; Female; Glioblastoma; Humans; Lomustine; Male; Middle Aged; O(6)-Methylguanine-DNA Methyltransferase; Predictive Value of Tests; Prognosis; Promoter Regions, Genetic; Radiotherapy, Adjuvant; Survival Analysis; Temozolomide; Treatment Outcome	2006
A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma. British journal of cancer, 2007, Jan-15, Volume: 96, Issue:1 Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Lomustine; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Neutropenia; Temozolomide; Thrombocytopenia; Treatment Failure	2007
A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood. Neuro-oncology, 2008, Volume: 10, Issue:4 Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Glioma; Humans; Lomustine; Maximum Tolerated Dose; Temozolomide	2008
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35 Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Disease Progression; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Administration Schedule; Female; Glioma; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Lomustine; Male; Middle Aged; Mutation; Procarbazine; Promoter Regions, Genetic; Proportional Hazards Models; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors; Temozolomide; Time Factors; Treatment Failure; Tumor Suppressor Proteins; Vincristine; Young Adult	2009
Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study. Neurosurgery, 2010, Volume: 66, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carboplatin; Cross-Linking Reagents; Dacarbazine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Injections, Intra-Arterial; Lomustine; Male; Melphalan; Middle Aged; Oligodendroglioma; Osmotic Pressure; Procarbazine; Temozolomide; Vincristine; Young Adult	2010
Impact of adjuvant chemotherapy for gliomatosis cerebri. BMC cancer, 2010, Aug-13, Volume: 10 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Child; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; Humans; Lomustine; Male; Middle Aged; Neoplasm Staging; Neoplasms, Neuroepithelial; Neoplasms, Radiation-Induced; Procarbazine; Prognosis; Retrospective Studies; Survival Rate; Temozolomide; Vincristine; Young Adult	2010
Temozolomide versus procarbazine, lomustine, and vincristine in recurrent high-grade glioma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Oct-20, Volume: 28, Issue:30 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Female; Glioma; Humans; Kaplan-Meier Estimate; Lomustine; Male; Middle Aged; Neoplasm Staging; Procarbazine; Proportional Hazards Models; Quality of Life; Recurrence; Risk Assessment; Risk Factors; Temozolomide; Time Factors; Treatment Outcome; United Kingdom; Vincristine	2010
Prognostic and predictive markers in recurrent high grade glioma; results from the BR12 randomised trial. Acta neuropathologica communications, 2014, Jun-20, Volume: 2 Topics: Antineoplastic Agents; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; DNA Repair Enzymes; DNA, Neoplasm; Female; Glioma; Humans; Isocitrate Dehydrogenase; Lomustine; Male; Predictive Value of Tests; Temozolomide; Tumor Suppressor Proteins; Vincristine	2014
Sunitinib Malate plus Lomustine for Patients with Temozolomide-refractory Recurrent Anaplastic or Low-grade Glioma. Anticancer research, 2015, Volume: 35, Issue:10 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Glioma; Humans; Indoles; Lomustine; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Pyrroles; Sunitinib; Survival Rate; Temozolomide	2015
The role of temozolomide in the management of patients with newly diagnosed anaplastic astrocytoma: a comparison of survival in the era prior to and following the availability of temozolomide. Journal of neuro-oncology, 2016, Volume: 127, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carmustine; Dacarbazine; Female; Follow-Up Studies; Humans; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Procarbazine; Prognosis; Retrospective Studies; Survival Rate; Temozolomide; Vincristine	2016
Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study. Neuro-oncology, 2016, Volume: 18, Issue:10 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Child; Child, Preschool; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Lomustine; Male; Temozolomide; Young Adult	2016
INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFR amplified glioblastoma. Neuro-oncology, 2020, 05-15, Volume: 22, Issue:5 Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Lomustine; Temozolomide	2020
MGMT promoter methylation analysis for allocating combined CCNU/TMZ chemotherapy: Lessons learned from the CeTeG/NOA-09 trial. International journal of cancer, 2021, 04-01, Volume: 148, Issue:7 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Cohort Studies; Correlation of Data; CpG Islands; DNA Methylation; Female; Glioblastoma; Humans; Lomustine; Male; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Regression Analysis; Temozolomide	2021
Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial. JAMA oncology, 2020, 12-01, Volume: 6, Issue:12 Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cytosine Deaminase; Female; Flucytosine; Glioma; Humans; Isocitrate Dehydrogenase; Lomustine; Male; Middle Aged; Recombinant Proteins; Standard of Care; Survival Analysis; Temozolomide; Treatment Outcome	2020
Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial. Journal of neuro-oncology, 2023, Volume: 161, Issue:1 Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Female; Glioblastoma; Humans; Lomustine; Prognosis; Temozolomide	2023

Other Studies

58 other study(ies) available for temozolomide and lomustine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
New Protocol-Guided Exploitation of a Lysosomal Sulfatase Inhibitor to Suppress Cell Growth in Glioblastoma Multiforme. Journal of medicinal chemistry, 2021, 06-24, Volume: 64, Issue:12 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Fluorescent Dyes; Glioblastoma; Glucosides; Humans; Lysosomes; Naphthalimides; Prognosis; Sulbactam; Sulfatases	2021
Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells. British journal of cancer, 1993, Volume: 67, Issue:6 Topics: Antineoplastic Agents; Dacarbazine; Drug Screening Assays, Antitumor; Drug Synergism; Guanine; Humans; Lomustine; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide; Tumor Cells, Cultured	1993
Sensitivity of short-term cultures derived from human malignant glioma to the anti-cancer drug temozolomide. Anti-cancer drugs, 1999, Volume: 10, Issue:2 Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glioblastoma; Humans; Inhibitory Concentration 50; Lomustine; Oligodendroglioma; Temozolomide; Tumor Cells, Cultured	1999
Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones. European journal of haematology, 2001, Volume: 67, Issue:1 Topics: Alkylating Agents; Alkylation; Animals; Carmustine; Cells, Cultured; Colony-Forming Units Assay; Dacarbazine; DNA Damage; DNA, Complementary; Drug Resistance; Genetic Vectors; Hematopoietic Stem Cells; Humans; Lomustine; Mice; Moloney murine leukemia virus; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Recombinant Fusion Proteins; Retroviridae; Sarcoma Viruses, Murine; Spleen Focus-Forming Viruses; Temozolomide; Terminal Repeat Sequences; Transfection	2001
Interobserver variability in the radiological assessment of response to chemotherapy in glioma. Neurology, 2003, Mar-11, Volume: 60, Issue:5 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Dacarbazine; Ependymoma; Female; Glioblastoma; Glioma; Humans; Image Enhancement; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Observer Variation; Oligodendroglioma; Paclitaxel; Procarbazine; Sensitivity and Specificity; Temozolomide; Tomography, X-Ray Computed; Treatment Outcome; Vincristine	2003
Long-term outcome of oligodendrogliomas. Neurology, 2004, May-25, Volume: 62, Issue:10 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Dacarbazine; Epilepsies, Partial; Etoposide; Female; Follow-Up Studies; Humans; Life Tables; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Nitrosourea Compounds; Oligodendroglioma; Organophosphorus Compounds; Procarbazine; Prognosis; Proportional Hazards Models; Radionuclide Imaging; Radiopharmaceuticals; Survival Analysis; Technetium Tc 99m Sestamibi; Temozolomide; Treatment Outcome; Vincristine	2004
Gliomatosis cerebri: better definition, better treatment. Neurology, 2004, Jul-27, Volume: 63, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Cell Cycle Proteins; Dacarbazine; Disease Progression; Female; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasms, Neuroepithelial; Nerve Tissue Proteins; Procarbazine; Temozolomide; Vincristine	2004
Survival following adjuvant PCV or temozolomide for anaplastic astrocytoma. Neuro-oncology, 2006, Volume: 8, Issue:3 Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Dacarbazine; Female; Humans; Lomustine; Male; Middle Aged; Procarbazine; Retrospective Studies; Survival Rate; Temozolomide; Vincristine	2006
Gliomatosis cerebri treatment in 11 elderly patients. Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:2 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression; Female; Humans; Lomustine; Magnetic Resonance Imaging; Male; Neoplasms, Neuroepithelial; Procarbazine; Survival Rate; Temozolomide	2006
Re-evaluation of the cost effectiveness of temozolomide for malignant gliomas in British Columbia. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2006, Volume: 12, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; British Columbia; Cost-Benefit Analysis; Dacarbazine; Disease-Free Survival; Female; Glioma; Humans; Lomustine; Male; Medical Records; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Survival Rate; Temozolomide; Treatment Outcome	2006
Cryptococcal meningitis in patients with glioma: a report of two cases. Journal of neuro-oncology, 2008, Volume: 89, Issue:1 Topics: Adult; Aged; Amphotericin B; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebrospinal Fluid; Cryptococcus neoformans; Dacarbazine; Dexamethasone; Fatal Outcome; Fluconazole; Flucytosine; Glioma; Humans; Immunosuppression Therapy; Lomustine; Male; Meningitis, Cryptococcal; Opportunistic Infections; Temozolomide; Treatment Outcome	2008
In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs. British journal of cancer, 2008, Jul-22, Volume: 99, Issue:2 Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytes; Carboplatin; Cell Line, Tumor; Cisplatin; Dacarbazine; Drug Screening Assays, Antitumor; Etoposide; Female; Glioblastoma; Glioma; Hepatocytes; Humans; Lomustine; Male; Membrane Glycoproteins; Middle Aged; Procarbazine; Recombinant Fusion Proteins; Temozolomide; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Vincristine	2008
Low-grade glioma: a challenge in therapeutic options: the role of radiotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19 Suppl 7 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Dacarbazine; Glioma; Humans; Lomustine; Neoplasm Recurrence, Local; Procarbazine; Prognosis; Radiotherapy; Radiotherapy Dosage; Temozolomide; Vincristine	2008
Long-term survival of patients with glioblastoma treated with radiotherapy and lomustine plus temozolomide. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Mar-10, Volume: 27, Issue:8 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Lomustine; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Temozolomide	2009
Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy. [corrected]. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Dacarbazine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression Regulation, Neoplastic; Glioma; Humans; Lomustine; Procarbazine; Promoter Regions, Genetic; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Research Design; Survival Analysis; Temozolomide; Time Factors; Treatment Failure; Tumor Suppressor Proteins; Vincristine	2009
Bevacizumab is active as a single agent against recurrent malignant gliomas. Anticancer research, 2010, Volume: 30, Issue:2 Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazine; Doxorubicin; Female; Glioma; Humans; Lomustine; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Procarbazine; Retrospective Studies; Survival Rate; Temozolomide; Treatment Outcome; Vincristine	2010
Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma. Journal of neuro-oncology, 2011, Volume: 102, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Capecitabine; Celecoxib; Dacarbazine; Deoxycytidine; Female; Fluorouracil; Glioblastoma; Gliosarcoma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Pyrazoles; Sulfonamides; Survival Rate; Temozolomide; Thioguanine; Treatment Outcome; Young Adult	2011
Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma. Journal of neuro-oncology, 2011, Volume: 103, Issue:1 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Proliferation; Cerebellar Neoplasms; Child; Child, Preschool; Dacarbazine; DNA Methylation; Female; Gene Expression Regulation, Enzymologic; Humans; Immunoenzyme Techniques; Lomustine; Male; Medulloblastoma; Multicenter Studies as Topic; Neuroectodermal Tumors, Primitive; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Promoter Regions, Genetic; Prospective Studies; Randomized Controlled Trials as Topic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Temozolomide	2011
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors. Neuro-oncology, 2011, Volume: 13, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chromosomes, Human, Pair 1; Cohort Studies; Combined Modality Therapy; Dacarbazine; Disease Progression; Female; Follow-Up Studies; Humans; International Agencies; Lomustine; Male; Middle Aged; Oligodendroglioma; Procarbazine; Radiotherapy; Retrospective Studies; Survival Rate; Temozolomide; Treatment Outcome; Vincristine; Young Adult	2011
[Brain metastasis in breast cancer]. Voprosy onkologii, 2011, Volume: 57, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Chemoradiotherapy; Dacarbazine; Dexamethasone; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Humans; Karnofsky Performance Status; Lomustine; Middle Aged; Retrospective Studies; Survival Analysis; Temozolomide; Treatment Outcome; Vincristine	2011
[Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab]. Bulletin du cancer, 2012, Feb-01, Volume: 99, Issue:2 Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Carmustine; Chemoradiotherapy; Chemotherapy, Adjuvant; Cohort Studies; Dacarbazine; Drug Therapy, Combination; Glioblastoma; Humans; Irinotecan; Lomustine; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Radiation-Sensitizing Agents; Retrospective Studies; Temozolomide	2012
Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-20, Volume: 30, Issue:21 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Contrast Media; Dacarbazine; Disease Progression; Fatal Outcome; Female; Gadolinium; Glioblastoma; Humans; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Radiotherapy, Adjuvant; Temozolomide; Treatment Outcome	2012
Salvage therapy with lomustine for temozolomide refractory recurrent anaplastic astrocytoma: a retrospective study. Journal of neuro-oncology, 2015, Volume: 122, Issue:2 Topics: Adult; Antineoplastic Agents, Alkylating; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Salvage Therapy; Temozolomide; Young Adult	2015
Clinical benefit in recurrent glioblastoma from adjuvant NovoTTF-100A and TCCC after temozolomide and bevacizumab failure: a preliminary observation. Cancer medicine, 2015, Volume: 4, Issue:3 Topics: Adult; Aged; Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Capecitabine; Celecoxib; Combined Modality Therapy; Dacarbazine; Electric Stimulation Therapy; Female; Glioblastoma; Humans; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Temozolomide; Thioguanine; Treatment Failure	2015
Treating anaplastic oligodendrogliomas and WHO grade 2 gliomas: PCV or temozolomide? The case for PCV. Oncology (Williston Park, N.Y.), 2015, Volume: 29, Issue:4 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dacarbazine; Evidence-Based Medicine; Glioma; Humans; Lomustine; Neoplasm Grading; Neoplasm Staging; Oligodendroglioma; Procarbazine; Prognosis; Radiotherapy, Adjuvant; Survival Analysis; Temozolomide; Treatment Outcome; Vincristine	2015
Treating anaplastic oligodendrogliomas and WHO grade 2 gliomas: PCV or temozolomide? The case for temozolomide. Oncology (Williston Park, N.Y.), 2015, Volume: 29, Issue:4 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Dacarbazine; Evidence-Based Medicine; Glioma; Humans; Lomustine; Neoplasm Grading; Neoplasm Staging; Oligodendroglioma; Procarbazine; Prognosis; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Survival Analysis; Temozolomide; Treatment Outcome; Vincristine	2015
High-grade glioma in children and adolescents: a single-center experience. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016, Volume: 32, Issue:2 Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Female; Glioblastoma; Humans; Karnofsky Performance Status; Lomustine; Male; Neurosurgical Procedures; Procarbazine; Prognosis; Proportional Hazards Models; Radiotherapy; Retrospective Studies; Survival Rate; Temozolomide; Vincristine	2016
Singapore Cancer Network (SCAN) Guidelines for Systemic Therapy of High-Grade Glioma. Annals of the Academy of Medicine, Singapore, 2015, Volume: 44, Issue:10 Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Bevacizumab; Brain Neoplasms; Camptothecin; Carboplatin; Chemoradiotherapy; Chemotherapy, Adjuvant; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Cyclophosphamide; Dacarbazine; Glioblastoma; Humans; Irinotecan; Lomustine; Neoplasm Grading; Neoplasm Recurrence, Local; Oligodendroglioma; Procarbazine; Radiotherapy; Singapore; Temozolomide; Teniposide; Vincristine	2015
Chemotherapy for intracranial ependymoma in adults. BMC cancer, 2016, Apr-23, Volume: 16 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Ependymoma; Epirubicin; Female; Humans; Ifosfamide; Kaplan-Meier Estimate; Lomustine; Male; Middle Aged; Procarbazine; Temozolomide; Treatment Outcome; Vincristine	2016
Acquired temozolomide resistance in human glioblastoma cell line U251 is caused by mismatch repair deficiency and can be overcome by lomustine. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2018, Volume: 20, Issue:4 Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dacarbazine; DNA Mismatch Repair; Drug Resistance, Neoplasm; Glioblastoma; Humans; Lomustine; Temozolomide	2018
Regimen of procarbazine, lomustine, and vincristine versus temozolomide for gliomas. Cancer, 2018, 07-01, Volume: 124, Issue:13 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Administration Schedule; Glioma; Humans; Lomustine; Neoplasm Grading; Procarbazine; Promoter Regions, Genetic; Quality of Life; Randomized Controlled Trials as Topic; Temozolomide; Tumor Suppressor Proteins; Vincristine	2018
Achievable Central Nervous System Concentrations of the Green Tea Catechin EGCG Induce Stress in Glioblastoma Cells in Vitro. Nutrition and cancer, 2018, Volume: 70, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Catechin; Central Nervous System; Dietary Supplements; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Glioblastoma; Humans; Lomustine; Promoter Regions, Genetic; Reactive Oxygen Species; Tea; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Proteins	2018
Radiotherapy plus temozolomide or PCV in patients with anaplastic oligodendroglioma 1p19q codeleted. Revista de neurologia, 2018, Oct-16, Volume: 67, Issue:8 Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Female; Gene Deletion; Humans; Lomustine; Male; Middle Aged; Oligodendroglioma; Procarbazine; Retrospective Studies; Temozolomide; Vincristine; Young Adult	2018
Improving survival in molecularly selected glioblastoma. Lancet (London, England), 2019, 02-16, Volume: 393, Issue:10172 Topics: Adult; Brain Neoplasms; Combined Modality Therapy; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Lomustine; Temozolomide; Tumor Suppressor Proteins	2019
Lomustine-temozolomide combination efficacious in newly diagnosed glioblastoma. Nature reviews. Clinical oncology, 2019, Volume: 16, Issue:5 Topics: Brain Neoplasms; Clinical Trials, Phase III as Topic; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Administration Schedule; Drug Therapy, Combination; Glioblastoma; Humans; Lomustine; Survival Analysis; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins	2019
A Real-World Claims Analysis of Costs and Patterns of Care in Treated Patients with Glioblastoma Multiforme in the United States. Journal of managed care & specialty pharmacy, 2019, Volume: 25, Issue:4 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Cost of Illness; Databases, Factual; Female; Glioblastoma; Health Care Costs; Hospitalization; Humans; Irinotecan; Lomustine; Male; Middle Aged; Prognosis; Retrospective Studies; Temozolomide; Time Factors; United States; Young Adult	2019
[Lomustine and temozolomide in combination with radiotherapy : New treatment option for patients with MGMT promoter methylated Glioblastoma]. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2019, Volume: 195, Issue:9 Topics: Antineoplastic Agents, Alkylating; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Lomustine; Temozolomide; Tumor Suppressor Proteins	2019
Combination chemotherapy with temozolomide, lomustine, vincristine and interferon-alpha (TOL-IFN) plus vemurafenib or TOL-IFN as first-line treatment for patients with advanced melanoma. Acta oncologica (Stockholm, Sweden), 2020, Volume: 59, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Female; Follow-Up Studies; Humans; Interferon-alpha; Lomustine; Male; Melanoma; Middle Aged; Prognosis; Survival Rate; Temozolomide; Vemurafenib; Vincristine	2020
Craniotomy for recurrent glioblastoma: Is it justified? A comparative cohort study with outcomes over 10 years. Clinical neurology and neurosurgery, 2020, Volume: 188 Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neoplasms; Chemoradiotherapy; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant; Cohort Studies; Craniotomy; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Karnofsky Performance Status; Lomustine; Male; Middle Aged; Neoplasm Recurrence, Local; Neurosurgical Procedures; Promoter Regions, Genetic; Proportional Hazards Models; Prospective Studies; Quality of Life; Radiotherapy; Radiotherapy, Adjuvant; Reoperation; Survival Rate; Temozolomide; Tumor Suppressor Proteins; Young Adult	2020
Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma. Journal of cancer research and clinical oncology, 2020, Volume: 146, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Disease-Free Survival; Electric Stimulation Therapy; Female; Glioblastoma; Humans; Lomustine; Male; Retrospective Studies; Temozolomide	2020
A troublesome burden, the amplification of EGFR in glioblastoma! Neuro-oncology, 2020, 05-15, Volume: 22, Issue:5 Topics: Antibodies, Monoclonal, Humanized; Brain Neoplasms; ErbB Receptors; Glioblastoma; Humans; Lomustine; Temozolomide	2020
Radiotherapy Plus Procarbazine, Lomustine, and Vincristine Versus Radiotherapy Plus Temozolomide for IDH-Mutant Anaplastic Astrocytoma: A Retrospective Multicenter Analysis of the French POLA Cohort. The oncologist, 2021, Volume: 26, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Humans; Lomustine; Procarbazine; Retrospective Studies; Temozolomide; Vincristine	2021
PCV chemotherapy alone for WHO grade 2 oligodendroglioma: prolonged disease control with low risk of malignant progression. Journal of neuro-oncology, 2021, Volume: 153, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Humans; Lomustine; Neoplasm Staging; Oligodendroglioma; Procarbazine; Temozolomide; Vincristine; World Health Organization	2021
Diagnosis of Pseudoprogression Following Lomustine-Temozolomide Chemoradiation in Newly Diagnosed Glioblastoma Patients Using FET-PET. Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 07-01, Volume: 27, Issue:13 Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Disease Progression; Female; Glioblastoma; Humans; Lomustine; Male; Middle Aged; Positron-Emission Tomography; Retrospective Studies; Temozolomide; Tyrosine	2021
Combination chemotherapy versus temozolomide for patients with methylated MGMT (m-MGMT) glioblastoma: results of computational biological modeling to predict the magnitude of treatment benefit. Journal of neuro-oncology, 2021, Volume: 153, Issue:3 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Artificial Intelligence; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Drug Therapy, Combination; Glioblastoma; Humans; Lomustine; Overtreatment; Pharmaceutical Preparations; Temozolomide; Tumor Suppressor Proteins	2021
Lomustine and nimustine exert efficient antitumor effects against glioblastoma models with acquired temozolomide resistance. Cancer science, 2021, Volume: 112, Issue:11 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Glioblastoma; Histones; Humans; Injections, Intraperitoneal; Lomustine; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Nimustine; Salvage Therapy; Temozolomide; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays	2021
Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets. Scientific reports, 2021, 10-13, Volume: 11, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Lomustine; Temozolomide	2021
Early Postoperative Treatment versus Initial Observation in CNS WHO Grade 2 and 3 Oligodendroglioma: Clinical Outcomes and DNA Methylation Patterns. Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 10-14, Volume: 28, Issue:20 Topics: Adult; Brain Neoplasms; DNA Methylation; Humans; Isocitrate Dehydrogenase; Lomustine; Methyltransferases; Oligodendroglioma; Procarbazine; Prospective Studies; Retrospective Studies; Temozolomide; Vincristine; World Health Organization	2022
Abrogation of Cellular Senescence Induced by Temozolomide in Glioblastoma Cells: Search for Senolytics. Cells, 2022, 08-19, Volume: 11, Issue:16 Topics: Artesunate; Cellular Senescence; Curcumin; Glioblastoma; Humans; Lomustine; Neoplasm Recurrence, Local; NF-kappa B; Poly(ADP-ribose) Polymerase Inhibitors; Senotherapeutics; Temozolomide	2022
Current therapeutic options for glioblastoma and future perspectives. Expert opinion on pharmacotherapy, 2022, Volume: 23, Issue:14 Topics: Antineoplastic Agents, Alkylating; Bevacizumab; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Lomustine; Neoplasm Recurrence, Local; Temozolomide	2022
Exploration of biomedical knowledge for recurrent glioblastoma using natural language processing deep learning models. BMC medical informatics and decision making, 2022, 10-13, Volume: 22, Issue:1 Topics: Bevacizumab; Chronic Disease; Clinical Trials as Topic; Deep Learning; Glioblastoma; Humans; Lomustine; Natural Language Processing; Nivolumab; Temozolomide	2022
CRISPR/Cas9-induced knockout reveals the role of ABCB1 in the response to temozolomide, carmustine and lomustine in glioblastoma multiforme. Pharmacological research, 2022, Volume: 185 Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carmustine; Cell Line, Tumor; CRISPR-Cas Systems; Drug Resistance, Neoplasm; Glioblastoma; Humans; Lomustine; Neoplasm Proteins; Temozolomide	2022
Tumor Treating Fields (TTFields) increase the effectiveness of temozolomide and lomustine in glioblastoma cell lines. Journal of neuro-oncology, 2023, Volume: 163, Issue:1 Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line; Cell Line, Tumor; DNA Modification Methylases; DNA Repair Enzymes; Glioblastoma; Humans; Lomustine; Temozolomide	2023
Triple combination of lomustine, temozolomide and irradiation reduces canine glioma cell survival in vitro. Veterinary medicine and science, 2023, Volume: 9, Issue:4 Topics: Animals; Cell Survival; Dacarbazine; Dog Diseases; Dogs; Glioma; Lomustine; Temozolomide	2023
Undetected pseudoprogressions in the CeTeG/NOA-09 trial: hints from postprogression survival and MRI analyses. Journal of neuro-oncology, 2023, Volume: 164, Issue:3 Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Glioblastoma; Humans; Lomustine; Magnetic Resonance Imaging; Temozolomide	2023