Page last updated: 2024-08-16

temozolomide and gdc 0449

temozolomide has been researched along with gdc 0449 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Bakker, A; Benedetti, G; De Rosa, A; Ferruzzi, P; Giordano, C; Magnoni, L; Magrini, R; Mennillo, F; Miragliotta, V; Mori, E; Pericot Mohr, Gl; Rossi, M; Thomas, R; Tunici, P1
Basu, A; Basu, P; Basu, SK; Bhattacharya, RN; Biswas, NK; Chandra, V; Chatterjee, A; Chattopadhyay, A; Das, S; Das, T; Dhara, S; Kumar, S; Maitra, A; Mukherjee, A; Sarkar-Roy, N; Tripathy, LN1
Bureta, C; Komiya, S; Maeda, S; Nagano, S; Saitoh, Y; Sasaki, H; Setoguchi, T; Taniguchi, N; Tokumoto, H1
Alicke, B; Choniawko, L; Forrest, WF; Gould, SE; Jakubczak, M; Mayba, O; Osinska, M; Piatkowski, P; Starr, A1
Barritault, M; Bidaux, AS; Bonneville-Levard, A; Chinot, O; Frappaz, D; Garin, G; Hottinger, AF; Laigle-Donadey, F; Le Rhun, E; Meyronnet, D; Montané, L; Pérol, D1

Trials

2 trial(s) available for temozolomide and gdc 0449

ArticleYear
Variant allele frequency enrichment analysis in vitro reveals sonic hedgehog pathway to impede sustained temozolomide response in GBM.
    Scientific reports, 2015, Jan-21, Volume: 5

    Topics: Alleles; Anilides; Cell Division; Cell Line, Tumor; Dacarbazine; Exome; Female; Follow-Up Studies; G2 Phase; Gene Frequency; Glioblastoma; Hedgehog Proteins; Humans; Male; Neoplasm Proteins; Pyridines; Radiography; Spheroids, Cellular; Temozolomide

2015
MEVITEM-a phase I/II trial of vismodegib + temozolomide vs temozolomide in patients with recurrent/refractory medulloblastoma with Sonic Hedgehog pathway activation.
    Neuro-oncology, 2021, 11-02, Volume: 23, Issue:11

    Topics: Anilides; Cerebellar Neoplasms; Hedgehog Proteins; Humans; Medulloblastoma; Pyridines; Temozolomide

2021

Other Studies

3 other study(ies) available for temozolomide and gdc 0449

ArticleYear
In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines.
    International journal of cancer, 2012, Jul-15, Volume: 131, Issue:2

    Topics: Anilides; Animals; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Gene Expression Profiling; Glioblastoma; Hedgehog Proteins; Humans; Mice; Mice, Nude; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction; Smoothened Receptor; Temozolomide; Transcription Factors; Veratrum Alkaloids; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1

2012
Synergistic effect of arsenic trioxide, vismodegib and temozolomide on glioblastoma.
    Oncology reports, 2019, Volume: 41, Issue:6

    Topics: Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Caspase 3; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Neoplasm Recurrence, Local; Pyridines; Signal Transduction; Temozolomide; Xenograft Model Antitumor Assays

2019
Generalized Additive Mixed Modeling of Longitudinal Tumor Growth Reduces Bias and Improves Decision Making in Translational Oncology.
    Cancer research, 2020, 11-15, Volume: 80, Issue:22

    Topics: Anilides; Animals; Antineoplastic Agents, Alkylating; Bias; Decision Making; Disease Models, Animal; Female; Genes, Tumor Suppressor; Glioblastoma; Heterografts; Humans; Medical Oncology; Mice; Mice, Nude; Models, Statistical; Neoplasm Transplantation; Neoplasms; Normal Distribution; Patched-1 Receptor; Piperazines; Pyridines; Random Allocation; Statistics, Nonparametric; Temozolomide; Translational Research, Biomedical; Tumor Burden

2020