temazepam has been researched along with oxazepam in 94 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (35.11) | 18.7374 |
| 1990's | 17 (18.09) | 18.2507 |
| 2000's | 20 (21.28) | 29.6817 |
| 2010's | 21 (22.34) | 24.3611 |
| 2020's | 3 (3.19) | 2.80 |
| Authors | Studies |
|---|---|
| Collins, RJ; Gall, M; Kamdar, BV | 1 |
| Babbini, M; Barbaro, AM; Bartoletti, M; Biagi, GL; Borea, PA; Gaiardi, M; Guerra, MC | 1 |
| Johnston, GA; Maddalena, DJ | 1 |
| Karplus, M; So, SS | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Du-Cuny, L; Huwyler, J; Kansy, M; Wiese, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Carmona, AV; Kumari, S; Tiwari, AK; Trippier, PC | 1 |
| Liljequist, R; Linnoila, M; Palva, E | 1 |
| Baars, AM; Hekster, YA; O'Reilly, WJ; van der Kleijn, E; Vree, TB | 1 |
| Stone, BM | 1 |
| Allen, MD; Greenblatt, DJ; Orsulak, PJ; Shader, RI; Woo, E | 1 |
| Clarke, CH; Nicholson, AN | 1 |
| Kanto, J; Mäenpää, M; Mäntylä, R; Sellman, R; Valovirta, E | 1 |
| Nicholson, AN | 1 |
| Loeffler, PM | 1 |
| Lewis, DC; Sullivan, JT; Swift, RM | 1 |
| Guentert, TW; Stebler, T | 1 |
| Baars, AM; Vree, TB; Wuis, EW | 1 |
| Lillywhite, KJ; Miners, JO | 1 |
| Dusci, LJ; Good, SM; Hall, RW; Ilett, KF | 1 |
| Chenery, RJ; Lockwood, GF; Seddon, T | 1 |
| Morino, A; Sugiyama, M | 1 |
| Morino, A; Nakamura, A; Nakanishi, K; Sugiyama, M; Tatewaki, N | 1 |
| Breen, KJ; Desmond, PV; Ghabrial, H; Gijsbers, AJ; Harman, PJ; Mashford, ML; Watson, KJ | 1 |
| Morino, A; Nakamura, A; Sugiyama, M; Tatewaki, N | 1 |
| Klockowski, PM; Levy, G | 2 |
| Brase, DA; Dewey, WL; Glennon, RA; Young, R | 1 |
| Igarashi, T; Kitagawa, H; Ohmori, S; Okiyama, M; Ueno, K | 1 |
| Clark, BJ; Fell, AF; Mama, JE; Noctor, TA | 1 |
| Brampton, WJ; Plantevin, OM | 1 |
| Moroji, T; Motomura, H; Noguchi, T; Sekiguchi, R; Tada, K | 1 |
| Martin, WR; McNicholas, LF; Pruitt, TA | 1 |
| Meeles, MT; Thys, CP; Tjaden, UR; van der Kaay, M | 1 |
| Auvinen, J; Lamminsivu, U; Linnoila, M; Viukari, M | 1 |
| Ballabio, M; Caccia, S; Garattini, S | 1 |
| El-Hazmi, MA | 1 |
| Löscher, W | 1 |
| MacKinnon, GL; Parker, WA | 1 |
| Bradshaw, EG; Greenwood, BK | 1 |
| Berlin, RM; Conell, LJ | 1 |
| Booij, LH; Crul, JF; Driessen, JJ; van Egmond, J; Vree, TB | 1 |
| Coffman, WB; McFarland, SA; Meyer, EA; Mumford, R; Wynn, RL | 1 |
| Chiba, K; Chiba, T; Hirano, T; Horii, H; Ishizaki, T; Kato, Y | 1 |
| Boonkerd, S; Detaevernier, MR; Michotte, Y; Vindevogel, J | 1 |
| Belal, F; Hefnawy, MM; Metwally, ME; Walash, MI | 1 |
| Buckley, NA; Dawson, AH; O'Connell, DL; Whyte, IM | 1 |
| Chosson, E; Farinotti, R; Gimenez, F; Uzan, S; Wainer, IW | 1 |
| Pang, KS; St-Pierre, MV | 1 |
| Ahonen, J; Neuvonen, PJ; Olkkola, KT | 1 |
| Ali, HM; Azzam, RM; Notarianni, LJ | 1 |
| Ackermann, I; Angermaier, L; Deinl, I; Franzelius, C; Machbert, G | 1 |
| Schoetz, G; Schurig, V; Trapp, O | 1 |
| Neuvonen, M; Ojanperä, I; Rasanen, I; Vuori, E | 1 |
| Bournique, JS; Dou, C; Gnezda, M; McNally, AJ; Salamone, SJ; Zinda, MK | 1 |
| Mørland, J; Olsen, KM; Skuterud, B; Smith-Kielland, A | 1 |
| Contel, N; Grossman, S; Liu, Z; Ren, S; Rose, A; Short, J; Unger, S | 1 |
| O'Neal, CL; Poklis, A | 1 |
| Chi, CL; Deng, Y; Lloyd, TL; Olah, TV; Unger, SE; Wu, JT | 1 |
| Chikhi-Chorfi, N; Claude, JR; Galons, H; Hua, H; Pham-Huy, C; Thevenin, M; Villain-Pautet, G; Warnet, JM | 1 |
| Deng, Y; Wu, JT; Zeng, H | 1 |
| Djeridane, Y; Touitou, Y | 1 |
| Deng, Y; Olah, TV; Wu, JT; Zhang, H | 1 |
| Dickson, SJ; Irving, RC | 1 |
| Kivelä, SL; Kukola, M; Laine, K; Nurminen, J; Puustinen, J; Vahlberg, T | 1 |
| Acikgöz, A; Bader, A; Giri, S; Karim, N; Schmidt-Heck, W | 1 |
| Billiot, E; Billiot, F; Warner, IM | 1 |
| Iannello, C; Mandrioli, R; Matrisciano, F; Mercolini, L; Nicoletti, F; Raggi, MA | 1 |
| Allen, KR; Glover, SJ | 1 |
| Bosker, FJ; Cremers, TI; Dremencov, E; Westerink, BH | 1 |
| Oechsler, S; Skopp, G | 1 |
| Beijnen, JH; Brandjes, DP; Huissoon, S; Lagas, JS; van den Dool, EJ; van der Heide, Y; Vos, RM; Wilhelm, AJ | 1 |
| Acikgöz, A; Bader, A; Giri, S; Maringka, M; Nieber, K | 1 |
| Begg, EJ; Chin, PK; Jensen, BP; Larsen, HS | 2 |
| Marin, SJ; McMillin, GA; Roberts, M; Wood, M | 1 |
| Liang, C; Ni, C; Rao, Y; Wang, R; Wang, X; Xiong, L; Zhang, Y | 1 |
| Atayee, RS; Best, BM; Luk, S; Ma, JD | 1 |
| Bertol, E; Boscolo Berto, R; Favretto, D; Mannaioni, G; Mari, F; Vaiano, F | 1 |
| Chester, SA; McIntire, GL; Morris, AA; Strickland, EC | 1 |
| Bankstahl, M; Gramer, M; Hausknecht, M; Klein, S; Löscher, W | 1 |
| Li, J; Liu, H; Wu, L; Zhang, J | 1 |
| Darwish, WS; Hayami, A; Ikenaka, Y; Ishizuka, M; Kawai, YK; Mizukawa, H; Nakayama, SM; Watanabe, KP | 1 |
| Jia, J; Jiang, F; Johansen, SS; Linnet, K; Rao, Y; Wang, X; Zhang, Y | 1 |
| Mangelings, D; Muscat Galea, C; Vander Heyden, Y | 1 |
| Castro, A; Costa, P; Franco, JM; Melo, P; Quintas, MJ; Tarelho, S; Teixeira, HM | 1 |
| Barra Caracciolo, A; Brodin, T; Earnshaw, M; Fick, J; Grabic, R; Grabicova, K; Heynen, M; Jonsson, M; Klaminder, J; Kodes, V; Lettieri, T; Loos, R; Randak, T; Slobodnik, J; Sweetman, A | 1 |
| Bertram, MG; Brodin, T; Cerveny, D; Fick, J; Klaminder, J | 1 |
| Coulter, C; Garnier, M; Moore, C | 1 |
6 review(s) available for temazepam and oxazepam
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.
Topics: Amides; Carbamates; Click Chemistry; Drug Design; Pyridines; Structure-Activity Relationship; Triazoles; Urea | 2020 |
Oral benzodiazepines and conscious sedation: a review.
Topics: Administration, Oral; Alprazolam; Ambulatory Surgical Procedures; Anti-Anxiety Agents; Conscious Sedation; Diazepam; Flurazepam; Humans; Lorazepam; Midazolam; Oxazepam; Premedication; Receptors, GABA-A; Temazepam; Triazolam | 1992 |
Benzodiazepine withdrawal syndrome: a literature review and evaluation.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Humans; Lorazepam; Nitrazepam; Oxazepam; Substance Withdrawal Syndrome; Substance-Related Disorders; Temazepam; Time Factors | 1982 |
8 trial(s) available for temazepam and oxazepam
| Article | Year |
|---|---|
Effects on learning and memory of 2-week treatments with chlordiazepoxide lactam, N-desmethyldiazepam, oxazepam and methyloxazepam, alone or in combination with alcohol.
Topics: Adult; Anti-Anxiety Agents; Chlordiazepoxide; Drug Interactions; Ethanol; Humans; Learning; Memory; Memory, Short-Term; Nordazepam; Oxazepam; Temazepam; Time Factors | 1979 |
Immediate and residual effects in man of the metabolites of diazepam.
Topics: Adult; Choice Behavior; Diazepam; Humans; Male; Motor Skills; Nordazepam; Oxazepam; Placebos; Reaction Time; Temazepam; Time Factors | 1978 |
Double-blind crossover study of the efficacy and acceptability of oxazepam Expidet tablets compared to placebo in patients undergoing gynaecological surgery.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Genital Diseases, Female; Humans; Middle Aged; Oxazepam; Preanesthetic Medication; Random Allocation; Sleep; Temazepam | 1985 |
Efficacy and side effects of lorazepam, oxazepam, and temazepam as sleeping aids in psychogeriatric inpatients.
Topics: Aged; Anti-Anxiety Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lorazepam; Mental Disorders; Oxazepam; Sleep; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Temazepam | 1980 |
Preoperative medication for day-case surgery. A comparison between oxazepam and temazepam.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anti-Anxiety Agents; Anxiety; Child; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxazepam; Preanesthetic Medication; Temazepam; Time Factors | 1983 |
Lack of effect of antimycotic itraconazole on the pharmacokinetics or pharmacodynamics of temazepam.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Antifungal Agents; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Humans; Itraconazole; Male; Oxazepam; Temazepam | 1996 |
Urinary excretion of diazepam metabolites in healthy volunteers and drug users.
Topics: Adult; Anti-Anxiety Agents; Chromatography, Gas; Chromatography, High Pressure Liquid; Creatinine; Diazepam; Female; Humans; Male; Middle Aged; Nordazepam; Oxazepam; Substance Abuse Detection; Substance-Related Disorders; Temazepam | 2001 |
Associations between use of benzodiazepines or related drugs and health, physical abilities and cognitive function: a non-randomised clinical study in the elderly.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Azabicyclo Compounds; Benzodiazepines; Cognition; Cognition Disorders; Data Collection; Drug Therapy, Combination; Female; Health Status; Humans; Hypnotics and Sedatives; Male; Oxazepam; Piperazines; Psychomotor Performance; Sex Factors; Temazepam | 2007 |
80 other study(ies) available for temazepam and oxazepam
| Article | Year |
|---|---|
Pharmacology of some metabolites of triazolam, alprazolam, and diazepam prepared by a simple, one-step oxidation of benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Diazepam; Hydroxylation; Male; Methods; Mice; Oxidation-Reduction; Triazolam; Triazoles | 1978 |
Rm values and structure-activity relationship of benzodiazepines.
Topics: Animals; Benzodiazepines; Chromatography, Thin Layer; Conflict, Psychological; Exploratory Behavior; Models, Biological; Rats; Solubility; Structure-Activity Relationship | 1980 |
Prediction of receptor properties and binding affinity of ligands to benzodiazepine/GABAA receptors using artificial neural networks.
Topics: Binding Sites; Ligands; Neural Networks, Computer; Predictive Value of Tests; Receptors, GABA-A; Structure-Activity Relationship | 1995 |
Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors.
Topics: Algorithms; Benzodiazepines; Models, Genetic; Nerve Net; Protein Binding; Receptors, GABA-A; Structure-Activity Relationship | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Computational aqueous solubility prediction for drug-like compounds in congeneric series.
Topics: Benzodiazepines; Computer Simulation; Crystallography, X-Ray; Databases, Factual; Least-Squares Analysis; Models, Chemical; Organic Chemicals; Pharmaceutical Preparations; Principal Component Analysis; Solubility; Sulfonamides; Water | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Simultaneous determination of diazepam and its metabolies N-desmethyldiazepam, oxydiazepam and oxazepam in plasma and urine of man and dog by means of high-performance liquid chromatography.
Topics: Animals; Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Diazepam; Dogs; Humans; Nordazepam; Oxazepam; Species Specificity; Temazepam | 1979 |
Diazepam and its hydroxylated metabolites: studies on sleep in healthy man.
Topics: Adult; Aging; Diazepam; Humans; Hydroxylation; Male; Middle Aged; Oxazepam; Sleep; Sleep, REM; Temazepam | 1979 |
Rapid recovery from massive diazepam overdose.
Topics: Adult; Biotransformation; Diazepam; Female; Half-Life; Humans; Male; Middle Aged; Nordazepam; Oxazepam; Remission, Spontaneous; Suicide, Attempted; Temazepam; Time Factors | 1978 |
Effect of age on the pharmacokinetics of diazepam given in conjunction with spinal anesthesia.
Topics: Adult; Age Factors; Aged; Anesthesia, Spinal; Body Water; Diazepam; Humans; Kinetics; Middle Aged; Nordazepam; Oxazepam; Temazepam | 1979 |
Performance studies with diazepam and its hydroxylated metabolites.
Topics: Barbiturates; Diazepam; Flurazepam; Humans; Hydroxylation; Motor Skills; Oxazepam; Temazepam; Time Factors | 1979 |
Benzodiazepine requirements during alcohol withdrawal syndrome: clinical implications of using a standardized withdrawal scale.
Topics: Administration, Oral; Adult; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Hospitalization; Humans; Length of Stay; Lorazepam; Neurologic Examination; Oxazepam; Retrospective Studies; Temazepam; Triazolam | 1991 |
Determination of diazepam and nordazepam in milk and plasma in the presence of oxazepam and temazepam.
Topics: Chromatography, High Pressure Liquid; Diazepam; Flurazepam; Humans; Hydrogen-Ion Concentration; Milk, Human; Nordazepam; Oxazepam; Temazepam | 1991 |
Direct high pressure liquid chromatographic analysis and preliminary pharmacokinetics of enantiomers of oxazepam and temazepam with their corresponding glucuronide conjugates.
Topics: Chromatography, High Pressure Liquid; Glucuronates; Humans; Male; Middle Aged; Oxazepam; Protein Binding; Stereoisomerism; Temazepam | 1991 |
Assessment of the drug inhibitor specificity of the human liver 4-methylumbelliferone UDP-glucuronosyltransferase activity.
Topics: Enzyme Induction; Fenoprofen; Glucuronosyltransferase; Humans; Hymecromone; Isoenzymes; Microsomes, Liver; Oxazepam; Salicylates; Salicylic Acid; Substrate Specificity; Temazepam | 1991 |
Excretion of diazepam and its metabolites in human milk during withdrawal from combination high dose diazepam and oxazepam.
Topics: Adult; Diazepam; Drug Combinations; Female; Humans; Infant; Milk, Human; Nordazepam; Oxazepam; Substance Withdrawal Syndrome; Substance-Related Disorders; Temazepam | 1990 |
In vitro drug metabolism and pharmacokinetics of diazepam in cynomolgus monkey hepatocytes during culture for six days.
Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Diazepam; Liver; Macaca fascicularis; Male; Models, Biological; Nordazepam; Oxazepam; Oxygenases; Temazepam; Time Factors | 1989 |
Relation between time courses of pharmacological effects and of plasma levels of camazepam and its active metabolites in rats.
Topics: Animals; Anti-Anxiety Agents; Biotransformation; Blood Proteins; Brain; Models, Biological; Muscle Relaxants, Central; Oxazepam; Pentylenetetrazole; Protein Binding; Rats; Temazepam; Time Factors | 1985 |
Species differences in the disposition and metabolism of camazepam.
Topics: Animals; Anti-Anxiety Agents; Blood Proteins; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Dogs; Feces; Half-Life; Haplorhini; Kinetics; Male; Mathematics; Mice; Oxazepam; Rats; Rats, Inbred Strains; Species Specificity; Temazepam | 1985 |
The effects of age and chronic liver disease on the elimination of temazepam.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Blood Proteins; Female; Half-Life; Humans; Kinetics; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Oxazepam; Protein Binding; Temazepam | 1986 |
The metabolic fate of camazepam in rats.
Topics: Animals; Anti-Anxiety Agents; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hydroxylation; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Methylation; Oxazepam; Rats; Rats, Inbred Strains; Temazepam | 1986 |
Kinetics of drug action in disease states. XXIV. Pharmacodynamics of diazepam and its active metabolites in rats.
Topics: Animals; Anti-Anxiety Agents; Brain; Diazepam; Female; Nordazepam; Oxazepam; Rats; Rats, Inbred Lew; Reflex; Temazepam | 1988 |
Potencies of diazepam metabolites in rats trained to discriminate diazepam.
Topics: Animals; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Nordazepam; Oxazepam; Rats; Rats, Inbred Strains; Temazepam | 1986 |
Simultaneous determination of diazepam and its active metabolites in rat serum, brain and cerebrospinal fluid by high-performance liquid chromatography.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Diazepam; Female; Nordazepam; Oxazepam; Postural Balance; Rats; Rats, Inbred Strains; Temazepam | 1987 |
Imipramine treatment alters the pharmacokinetics and pharmacodynamics of diazepam.
Topics: Animals; Blood Proteins; Brain Chemistry; Diazepam; Drug Interactions; Imipramine; Liver; Male; Nordazepam; Oxazepam; Pentylenetetrazole; Protein Binding; Rats; Rats, Inbred Strains; Temazepam | 1987 |
Computer-aided optimisation of drug enantiomer separation in chiral high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Lorazepam; Microcomputers; Oxamniquine; Oxazepam; Software; Stereoisomerism; Temazepam | 1988 |
Liquid-chromatographic assay of diazepam and its major metabolites in serum, and application to pharmacokinetic study of high doses of diazepam in schizophrenics.
Topics: Administration, Oral; Chromatography, High Pressure Liquid; Diazepam; Female; Humans; Kinetics; Nordazepam; Oxazepam; Schizophrenia; Temazepam | 1985 |
N-desmethyldiazepam physical dependence in dogs.
Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazepam; Muscle Spasticity; Nordazepam; Oxazepam; Paresthesia; Substance Withdrawal Syndrome; Temazepam; Time Factors | 1985 |
Determination of some benzodiazepines and metabolites in serum, urine and saliva by high-performance liquid chromatography.
Topics: Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Diazepam; Humans; Mathematics; Nordazepam; Oxazepam; Saliva; Temazepam | 1980 |
Relationship between camazepam, N-methyl-oxazepam and oxazepam brain concentrations and antileptazol effect in the rat.
Topics: Animals; Anti-Anxiety Agents; Brain; Brain Chemistry; Male; Oxazepam; Pentylenetetrazole; Rats; Temazepam | 1981 |
Aspects of the interaction of thyroxine and its binding serum proteins with 1,4-benzodiazepine tranquillizers.
Topics: Anti-Anxiety Agents; Autoradiography; Binding, Competitive; Chlordiazepoxide; Diazepam; Electrophoresis, Polyacrylamide Gel; Humans; Male; Nordazepam; Oxazepam; Temazepam; Thyroxine; Thyroxine-Binding Proteins | 1981 |
Rapid gas chromatographic measurement of diazepam and its metabolites desmethyldiazepam, oxazepam, and 3-hydroxydiazepam (temazepam) in small samples of plasma.
Topics: Anti-Anxiety Agents; Biotransformation; Chromatography, Gas; Diazepam; Humans; Nordazepam; Oxazepam; Temazepam | 1982 |
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Half-Life; Humans; Oxazepam; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Temazepam | 1983 |
In vitro interaction of diazepam and oxazepam with pancuronium and suxamethonium.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Muscle Contraction; Neuromuscular Junction; Nordazepam; Oxazepam; Pancuronium; Rats; Rats, Inbred Strains; Succinylcholine; Temazepam | 1984 |
Structure activity relationships of selected benzodiazepines as anticonvulsants to local anesthetics.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Benzodiazepines; Diazepam; Lidocaine; Male; Mepivacaine; Mice; Nitrazepam; Nordazepam; Oxazepam; Prilocaine; Seizures; Structure-Activity Relationship; Temazepam | 1980 |
Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; Medazepam; Nitrazepam; Oxazepam; Safety; Substance Withdrawal Syndrome; Substance-Related Disorders; Temazepam; Triazolam | 1980 |
Development and preliminary application of high-performance liquid chromatographic assay of urinary metabolites of diazepam in humans.
Topics: Chromatography, High Pressure Liquid; Diazepam; Humans; Nordazepam; Oxazepam; Reference Values; Reproducibility of Results; Temazepam | 1995 |
Suppression of chiral recognition of 3-hydroxy-1,4-benzodiazepines during micellar electrokinetic capillary chromatography with bile salts.
Topics: Anti-Anxiety Agents; Benzodiazepines; Bile Acids and Salts; Capillary Action; Chromatography; Kinetics; Lorazepam; Micelles; Oxazepam; Temazepam | 1995 |
A selective fluorimetric method for the determination of some 1,4-benzodiazepine drugs containing a hydroxyl group at C-3.
Topics: Anti-Anxiety Agents; Benzodiazepines; Fluorometry; Humans; Hydroxyl Radical; Lorazepam; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxazepam; Oxidation-Reduction; Temazepam | 1994 |
Relative toxicity of benzodiazepines in overdose.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Coma; Consciousness; Drug Overdose; Female; Follow-Up Studies; Humans; Male; Middle Aged; Oxazepam; Prospective Studies; Temazepam | 1995 |
Influence of specific albumin ligand markers used as modifiers on the separation of benzodiazepine enantiomers by chiral liquid chromatography on a human serum albumin column.
Topics: Anti-Anxiety Agents; Chromatography, Affinity; Chromatography, Liquid; Humans; Ligands; Lorazepam; Oxazepam; Serum Albumin; Stereoisomerism; Temazepam; Warfarin | 1993 |
Kinetics of sequential metabolism. I. Formation and metabolism of oxazepam from nordiazepam and temazepam in the perfused murine liver.
Topics: Animals; Kinetics; Male; Mice; Microsomes, Liver; Nordazepam; Oxazepam; Perfusion; Proteins; Temazepam | 1993 |
Rapid and simple chromatographic method for the determination of diazepam and its major metabolites in human plasma and urine.
Topics: Calibration; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Humans; Nordazepam; Oxazepam; Reference Values; Temazepam | 1998 |
Simultaneous extraction of selected benzodiazepines and benzodiazepine-glucuronides from urine by immunoadsorption.
Topics: Anti-Anxiety Agents; Diazepam; Glucuronates; Humans; Immunosorbent Techniques; Immunosorbents; Lorazepam; Oxazepam; Temazepam | 1998 |
Dynamic micellar electrokinetic chromatography. Determination of the enantiomerization barriers of oxazepam, temazepam, and lorazepam.
Topics: Algorithms; Anti-Anxiety Agents; Chromatography, Micellar Electrokinetic Capillary; Computer Simulation; Lorazepam; Oxazepam; Stereoisomerism; Temazepam | 2000 |
Benzodiazepine findings in blood and urine by gas chromatography and immunoassay.
Topics: Anti-Anxiety Agents; Chromatography, Gas; Coroners and Medical Examiners; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Immunoassay; Oxazepam; Temazepam; Toxicology | 2000 |
Comparison of the rates of hydrolysis of lorazepam-glucuronide, oxazepam-glucuronide and tamazepam-glucuronide catalyzed by E. coli beta-D-glucuronidase using the on-line benzodiazepine screening immunoassay on the Roche/Hitachi 917 analyzer.
Topics: Anti-Anxiety Agents; Escherichia coli; Forensic Medicine; Glucuronidase; Glucuronides; Humans; Hydrogen-Ion Concentration; Hydrolysis; Immunoassay; Lorazepam; Oxazepam; Temazepam; Temperature; Urinalysis | 2001 |
The simultaneous determination of diazepam and its three metabolites in dog plasma by high-performance liquid chromatography with mass spectroscopy detection.
Topics: Animals; Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Diazepam; Dogs; Mass Spectrometry; Nordazepam; Oxazepam; Reproducibility of Results; Temazepam | 2001 |
Commentary on: Dou C, Bournique J, Zinda M, Gnezda M, Nally A, Salamone S. Comparison of rates of hydrolysis of lorazepam-glucuronide, oxazepam-glucuronide and temazepam-glucuronide catalyzed by E. coli beta-glucuronidase using the on-line benzodiazepine
Topics: Benzodiazepines; Escherichia coli; Glucuronidase; Humans; Hydrolysis; Immunoassay; Lorazepam; Oxazepam; Temazepam | 2002 |
High-speed gradient parallel liquid chromatography/tandem mass spectrometry with fully automated sample preparation for bioanalysis: 30 seconds per sample from plasma.
Topics: Animals; Automation; Blood Chemical Analysis; Chromatography, Liquid; Dogs; Humans; Mass Spectrometry; Oxazepam; Pharmaceutical Preparations; Robotics; Sensitivity and Specificity; Temazepam | 2002 |
Separation of oxazepam, lorazepam, and temazepam enantiomers by HPLC on a derivatized cyclodextrin-bonded phase: application to the determination of oxazepam in plasma.
Topics: Animals; Benzodiazepinones; Chromatography, High Pressure Liquid; Cyclodextrins; Lorazepam; Optical Rotation; Oxazepam; Quality Control; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Temazepam | 2002 |
Fast analysis using monolithic columns coupled with high-flow on-line extraction and electrospray mass spectrometric detection for the direct and simultaneous quantitation of multiple components in plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Fenfluramine; Oxazepam; Rats; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tamoxifen; Temazepam | 2003 |
Effects of diazepam and its metabolites on nocturnal melatonin secretion in the rat pineal and Harderian glands. A comparative in vivo and in vitro study.
Topics: Animals; Circadian Rhythm; Diazepam; Harderian Gland; In Vitro Techniques; Male; Melatonin; Nordazepam; Oxazepam; Perfusion; Pineal Gland; Rats; Rats, Wistar; Temazepam | 2003 |
Quantitation of drug metabolites in the absence of pure metabolite standards by high-performance liquid chromatography coupled with a chemiluminescence nitrogen detector and mass spectrometer.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Luminescent Measurements; Mass Spectrometry; Nitrogen; Oxazepam; Pharmaceutical Preparations; Reference Standards; Sensitivity and Specificity; Temazepam | 2004 |
The detection of sedatives in hair and nail samples using tandem LC-MS-MS.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Azabicyclo Compounds; Benzodiazepines; Chromatography, Liquid; Clobazam; Clonazepam; Diazepam; Female; Forensic Pathology; Hair; Humans; Hypnotics and Sedatives; Male; Mass Spectrometry; Midazolam; Middle Aged; Nails; Oxazepam; Piperazines; Predictive Value of Tests; Rape; Temazepam; Triazolam | 2007 |
Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes.
Topics: Anti-Inflammatory Agents; Antithyroid Agents; Biotransformation; Cell Separation; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dexamethasone; Diazepam; Enzyme Induction; Hepatocytes; Humans; Hypnotics and Sedatives; Models, Biological; Models, Statistical; Nordazepam; Organ Culture Techniques; Oxazepam; Phenobarbital; Temazepam | 2009 |
Optimization of 12 chiral analytes with 8 polymeric surfactants.
Topics: Alprenolol; Amino Acids; Benzodiazepinones; Buffers; Diamines; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Lorazepam; Naphthalenes; Naphthols; Organophosphates; Oxazepam; Oxprenolol; Propanolamines; Propranolol; Stereoisomerism; Surface-Active Agents; Temazepam | 2008 |
Simultaneous analysis of diazepam and its metabolites in rat plasma and brain tissue by HPLC-UV and SPE.
Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Diazepam; Nordazepam; Oxazepam; Rats; Reproducibility of Results; Solid Phase Extraction; Spectrophotometry, Ultraviolet; Temazepam | 2009 |
Measurement of benzodiazepines in urine by liquid chromatography-tandem mass spectrometry: confirmation of samples screened by immunoassay.
Topics: Benzodiazepines; Biological Assay; Calibration; Chromatography, Liquid; European Union; Immunoassay; Limit of Detection; Nitrazepam; Nordazepam; Oxazepam; Sensitivity and Specificity; Tandem Mass Spectrometry; Temazepam | 2010 |
Oxazepam and temazepam attenuate paroxetine-induced elevation of serotonin levels in guinea-pig hippocampus.
Topics: Analysis of Variance; Animals; Drug Interactions; GABA Modulators; Guinea Pigs; Hippocampus; Male; Microdialysis; Oxazepam; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Temazepam; Time Factors | 2010 |
An in vitro approach to estimate putative inhibition of buprenorphine and norbuprenorphine glucuronidation.
Topics: Amitriptyline; Buprenorphine; Central Nervous System Agents; Chromatography, Liquid; Glucuronosyltransferase; Humans; In Vitro Techniques; Lamotrigine; Liver; Mass Spectrometry; Microsomes, Liver; Narcotics; Nortriptyline; Oxazepam; Temazepam; Triazines | 2010 |
Toxicokinetics of a dipyridamole (Persantin) intoxication: case report.
Topics: Anti-Anxiety Agents; Dipyridamole; Female; Humans; Middle Aged; Oxazepam; Platelet Aggregation Inhibitors; Suicide, Attempted; Temazepam | 2011 |
Biotransformation of diazepam in a clinically relevant flat membrane bioreactor model using primary porcine hepatocytes.
Topics: Adult; Animals; Bioreactors; Biotransformation; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Diazepam; Female; Hepatocytes; Humans; Inactivation, Metabolic; Liver, Artificial; Male; Nordazepam; Oxazepam; Swine; Temazepam; Young Adult | 2011 |
Quantification of total and unbound concentrations of lorazepam, oxazepam and temazepam in human plasma by ultrafiltration and LC-MS/MS.
Topics: Anti-Anxiety Agents; Calibration; Chromatography, Liquid; Hemofiltration; Humans; Lorazepam; Oxazepam; Tandem Mass Spectrometry; Temazepam | 2011 |
Adult age and ex vivo protein binding of lorazepam, oxazepam and temazepam in healthy subjects.
Topics: Adolescent; Adult; Age Factors; Aged; Female; Humans; Lorazepam; Male; Middle Aged; Oxazepam; Protein Binding; Serum Albumin; Temazepam; Young Adult | 2011 |
Sensitive UPLC-MS-MS assay for 21 benzodiazepine drugs and metabolites, zolpidem and zopiclone in serum or plasma.
Topics: Azabicyclo Compounds; Benzodiazepines; Chromatography, Liquid; Humans; Liquid-Liquid Extraction; Lorazepam; Mass Spectrometry; Nordazepam; Oxazepam; Piperazines; Plasma; Pyridines; Serum; Specimen Handling; Tandem Mass Spectrometry; Temazepam; Triazolam; Zolpidem | 2012 |
Direct determination of diazepam and its glucuronide metabolites in human whole blood by μElution solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Diazepam; Forensic Toxicology; Humans; Hypnotics and Sedatives; Limit of Detection; Nordazepam; Oxazepam; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry; Temazepam | 2013 |
Urinary diazepam metabolite distribution in a chronic pain population.
Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chronic Pain; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diazepam; Drug Interactions; Esomeprazole; Female; Fluoxetine; Humans; Male; Methadone; Nordazepam; Oxazepam; Retrospective Studies; Specimen Handling; Temazepam | 2014 |
A mixed MDPV and benzodiazepine intoxication in a chronic drug abuser: determination of MDPV metabolites by LC-HRMS and discussion of the case.
Topics: Adult; Alprazolam; Benzodiazepines; Benzodioxoles; Chlordiazepoxide; Chromatography, Liquid; Diazepam; Humans; Hypnotics and Sedatives; Male; Mass Spectrometry; Nordazepam; Oxazepam; Psychotropic Drugs; Pyrrolidines; Substance-Related Disorders; Synthetic Cathinone; Temazepam | 2014 |
Rapid enzymatic hydrolysis using a novel recombinant β-glucuronidase in benzodiazepine urinalysis.
Topics: Benzodiazepines; Chromatography, High Pressure Liquid; Glucuronidase; Glucuronides; Humans; Hydrolysis; Lorazepam; Oxazepam; Tandem Mass Spectrometry; Temazepam; Urinalysis | 2014 |
Low doses of ethanol markedly potentiate the anti-seizure effect of diazepam in a mouse model of difficult-to-treat focal seizures.
Topics: Animals; Anticonvulsants; Brain; Diazepam; Disease Models, Animal; Drug Compounding; Drug Synergism; Electroencephalography; Epilepsy, Temporal Lobe; Ethanol; Female; Kainic Acid; Mice; Nordazepam; Oxazepam; Seizures; Solvents; Temazepam; Water | 2014 |
A comparative study of primary secondary amino (PSA) and multi-walled carbon nanotubes (MWCNTs) as QuEChERS absorbents for the rapid determination of diazepam and its major metabolites in fish samples by high-performance liquid chromatography-electrospray
Topics: Adsorption; Animals; Chromatography, High Pressure Liquid; Diazepam; Fishes; Food Contamination; Nanotubes, Carbon; Nordazepam; Oxazepam; Seafood; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Temazepam | 2016 |
Characterization of equine cytochrome P450: role of CYP3A in the metabolism of diazepam.
Topics: Animals; Chlorocebus aethiops; COS Cells; Cytochrome P-450 CYP3A; Diazepam; Horses; Hypnotics and Sedatives; Male; Microsomes, Liver; Nordazepam; Oxazepam; Phylogeny; Protein Isoforms; Rats; Rats, Sprague-Dawley; Species Specificity; Temazepam | 2016 |
Deposition of diazepam and its metabolites in hair following a single dose of diazepam.
Topics: Adult; Asian People; Chromatography, Liquid; Diazepam; Female; Hair; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Nordazepam; Oxazepam; Tandem Mass Spectrometry; Temazepam; Young Adult | 2017 |
Investigation of the effect of mobile phase composition on selectivity using a solvent-triangle based approach in achiral SFC.
Topics: 1-Propanol; Acetonitriles; Benzodiazepines; Chromatography, Supercritical Fluid; Diazepam; Drug Contamination; Ethanol; Furans; Hydrogen Bonding; Lorazepam; Methanol; Multivariate Analysis; Organic Chemicals; Oxazepam; Principal Component Analysis; Reproducibility of Results; Silicon Dioxide; Solvents; Temazepam | 2017 |
Pentobarbital in the context of possible suicides: Analysis of a Case.
Topics: Adult; Central Nervous System Depressants; Diazepam; Ethanol; Gastrointestinal Contents; Humans; Male; Nordazepam; Oxazepam; Pentobarbital; Suicide; Temazepam | 2017 |
Screening of benzodiazepines in thirty European rivers.
Topics: Benzodiazepines; Clobazam; Environmental Monitoring; Europe; Oxazepam; Rivers; Temazepam; Water Pollutants, Chemical | 2017 |
Exposure via biotransformation: Oxazepam reaches predicted pharmacological effect levels in European perch after exposure to temazepam.
Topics: Animals; Biotransformation; Hypnotics and Sedatives; Oxazepam; Perches; Temazepam; Water Pollutants, Chemical | 2021 |
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases.
Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem | 2022 |