Compounds > telmisartan
Page last updated: 2024-08-24

telmisartan and leptin

telmisartan has been researched along with leptin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (14.29)29.6817
2010's9 (64.29)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Ak, ND; Fujisaka, S; Hachiya, H; Iwata, M; Kobayashi, M; Murakami, S; Sasaoka, T; Satoh, A; Senda, S; Takano, A; Takata, M; Temaru, R; Urakaze, M; Usui, I; Yamazaki, K; Yamazaki, Y1
Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, R; Gravina, A; Piccinni, MN; Pricolo, F; Ragonesi, PD; Salvadeo, SA1
Limor, R; Oron, Y; Rosenthal, T; Stern, N; Younis, F; Zangen, S1
Ebihara, K; Kusakabe, T; Kuwahara, K; Li, Y; Murray, M; Nakao, K; Naowaboot, J; Rong, X; Zhao, M1
Jöhren, O; Miesel, A; Müller-Fielitz, H; Raasch, W; Vogt, FM1
Barkhausen, J; Hübel, N; Mildner, M; Müller-Fielitz, H; Raasch, W; Vogt, FM1
Balam-Salazar, LB; Cardona-Muñoz, EG; Curiel-Beltrán, JA; de Jesús Romero-Prado, MM; Miramontes-Espino, MV; Rios-Arellano, A1
Bader, M; Barkhausen, J; Raasch, W; Santos, RA; Schuchard, J; Schuster, F; Stölting, I; Thorns, C; Vogt, FM; Winkler, M1
Cai, J; Cheng, S; Gao, L; Li, H; Li, M; Liu, P; Song, Y; Tian, G; Wang, Y; Yang, S; Yin, Y; Zhang, H1
Jöhren, O; Mildner, M; Müller-Fielitz, H; Raasch, W; Steckelings, M; Stölting, I1
Banks, WA; Huber, G; Hübner, N; Raasch, W; Saar, K; Schuster, F; Stölting, I; Wing, EE1
Frydrychowicz, A; Hübner, N; Kuerschner, L; Nickel, L; Othman, A; Raasch, W; Rawish, E; Saar, K; Schuster, F; Stölting, I1
Chen, H; Li, M; Liu, L; Tian, G; Zhu, D1
Hattori, N; Matsuda, T; Nakatsuji, S; Nishiyama, N; Shimatsu, A; Yamada, A1

Trials

3 trial(s) available for telmisartan and leptin

ArticleYear
Telmisartan reduced blood pressure and HOMA-IR with increasing plasma leptin level in hypertensive and type 2 diabetic patients.
    Diabetes research and clinical practice, 2007, Volume: 77, Issue:2

    Topics: Adiponectin; Adult; Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diet, Diabetic; Female; Humans; Hypertension; Hypoglycemic Agents; Leptin; Lipids; Male; Middle Aged; Telmisartan

2007
Telmisartan and irbesartan therapy in type 2 diabetic patients treated with rosiglitazone: effects on insulin-resistance, leptin and tumor necrosis factor-alpha.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:11

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Irbesartan; Leptin; Lipids; Male; Middle Aged; Rosiglitazone; Telmisartan; Tetrazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha

2006
Dietary flavonoids added to pharmacological antihypertensive therapy are effective in improving blood pressure.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 117, Issue:1

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Benzoates; Biomarkers; Blood Pressure; C-Reactive Protein; Cacao; Candy; Captopril; Combined Modality Therapy; Diet; Female; Flavonoids; Fruit; Humans; Hypertension; Leptin; Lipids; Male; Malus; Mexico; Middle Aged; Tea; Telmisartan; Time Factors; Treatment Outcome; Young Adult

2015

Other Studies

11 other study(ies) available for telmisartan and leptin

ArticleYear
Telmisartan ameliorates hyperglycemia and metabolic profile in nonobese Cohen-Rosenthal diabetic hypertensive rats via peroxisome proliferator activator receptor-gamma activation.
    Metabolism: clinical and experimental, 2010, Volume: 59, Issue:8

    Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Humans; Hyperglycemia; Hypertension; Insulin; Insulin Resistance; Leptin; PPAR gamma; Rats; Rats, Inbred SHR; Rosiglitazone; Telmisartan; Thiazolidinediones; Tumor Necrosis Factor-alpha; Weight Gain

2010
Angiotensin II type 1 receptor-independent beneficial effects of telmisartan on dietary-induced obesity, insulin resistance and fatty liver in mice.
    Diabetologia, 2010, Volume: 53, Issue:8

    Topics: Adipocytes; Adipose Tissue, White; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Cell Size; Diet, High-Fat; Fatty Liver; Insulin; Insulin Resistance; Leptin; Lipids; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Obesity, Abdominal; Organ Size; PPAR gamma; Receptor, Angiotensin, Type 1; Telmisartan; Triglycerides

2010
Double blockade of angiotensin II (AT(1) )-receptors and ACE does not improve weight gain and glucose homeostasis better than single-drug treatments in obese rats.
    British journal of pharmacology, 2012, Volume: 165, Issue:8

    Topics: Adipose Tissue; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Corticosterone; Drug Therapy, Combination; Feeding Behavior; Heart Rate; Leptin; Male; Obesity; Ramipril; Rats; Rats, Inbred SHR; Telmisartan; Weight Gain

2012
Chronic blockade of angiotensin AT₁ receptors improves cardinal symptoms of metabolic syndrome in diet-induced obesity in rats.
    British journal of pharmacology, 2014, Volume: 171, Issue:3

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Obesity Agents; Antihypertensive Agents; Behavior, Animal; Benzimidazoles; Benzoates; Diet, High-Fat; Dietary Sucrose; Drug Therapy, Combination; Energy Intake; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Insulin Resistance; Leptin; Male; Metabolic Syndrome; Obesity; Random Allocation; Rats; Rats, Inbred SHR; Telmisartan; Weight Gain

2014
Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway.
    British journal of pharmacology, 2015, Volume: 172, Issue:15

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Benzimidazoles; Benzoates; Diet; Energy Intake; Energy Metabolism; Insulin Resistance; Leptin; Male; Obesity; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Telmisartan; Weight Gain; Weight Loss

2015
Telmisartan Ameliorates Nephropathy in Metabolic Syndrome by Reducing Leptin Release From Perirenal Adipose Tissue.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:2

    Topics: Adipogenesis; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Disease Models, Animal; Intra-Abdominal Fat; Kidney Diseases; Leptin; Male; Metabolic Syndrome; Protective Agents; Rats; Rats, Wistar; Telmisartan

2016
Glucagon increase after chronic AT
    Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Line; Dose-Response Relationship, Drug; Glucagon; Hypoglycemic Agents; Islets of Langerhans; Leptin; Male; Mice, Inbred C57BL; Rats, Sprague-Dawley; Rats, Zucker; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Time Factors; Up-Regulation

2017
Telmisartan prevents diet-induced obesity and preserves leptin transport across the blood-brain barrier in high-fat diet-fed mice.
    Pflugers Archiv : European journal of physiology, 2018, Volume: 470, Issue:11

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Obesity Agents; Blood-Brain Barrier; Body Weight; Cell Line; Diet, High-Fat; Energy Metabolism; Humans; Leptin; Male; Mice; Mice, Inbred C57BL; Obesity; Telmisartan

2018
Telmisartan prevents development of obesity and normalizes hypothalamic lipid droplets.
    The Journal of endocrinology, 2020, 01-01, Volume: 244, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Diet, High-Fat; Hypothalamus; Leptin; Lipid Droplets; Lipid Metabolism; Mice; Mice, Inbred C57BL; Obesity; Telmisartan; Weight Gain

2020
Telmisartan improves myocardial remodeling by inhibiting leptin autocrine activity and activating PPARγ.
    Experimental biology and medicine (Maywood, N.J.), 2020, Volume: 245, Issue:7

    Topics: Animals; Antihypertensive Agents; Autocrine Communication; Hypertension; Leptin; Male; Myocardium; PPAR gamma; Rats; Rats, Sprague-Dawley; Telmisartan; Ventricular Remodeling

2020
Telmisartan is the most effective ARB to increase adiponectin via PPARα in adipocytes.
    Journal of molecular endocrinology, 2022, 05-10, Volume: 69, Issue:1

    Topics: Adipocytes; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzoates; Humans; Inflammation; Irbesartan; Leptin; PPAR alpha; PPAR gamma; RNA, Messenger; Telmisartan

2022