telmisartan, hydrochlorothiazide drug combination and nifedipine

telmisartan, hydrochlorothiazide drug combination has been researched along with nifedipine in 2 studies

Compound Research Comparison

Studies (telmisartan, hydrochlorothiazide drug combination)	Trials (telmisartan, hydrochlorothiazide drug combination)	Recent Studies (post-2010) (telmisartan, hydrochlorothiazide drug combination)	Studies (nifedipine)	Trials (nifedipine)	Recent Studies (post-2010) (nifedipine)
34	10	15	16,024	2,496	1,505

Protein Interaction Comparison

Protein	Taxonomy	nifedipine (IC50)
perilipin-5	Homo sapiens (human)	7.133
perilipin-1	Homo sapiens (human)	9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	Homo sapiens (human)	8.376
Voltage-dependent L-type calcium channel subunit alpha-1C	Cavia porcellus (domestic guinea pig)	0.0429
Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)	0.035
Cytochrome P450 1A2	Homo sapiens (human)	0.3
Cytochrome P450 3A4	Homo sapiens (human)	10
Adenosine receptor A3	Homo sapiens (human)	7.214
Cytochrome P450 2C9	Homo sapiens (human)	3.06
5-hydroxytryptamine receptor 2A	Rattus norvegicus (Norway rat)	10
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	7.214
Voltage-dependent L-type calcium channel subunit alpha-1C	Rattus norvegicus (Norway rat)	0.0385
Potassium voltage-gated channel subfamily A member 5	Homo sapiens (human)	6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	Rattus norvegicus (Norway rat)	1.12
Adenosine receptor A1	Homo sapiens (human)	7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2	Rattus norvegicus (Norway rat)	1.12
C-C chemokine receptor type 2	Homo sapiens (human)	2.191
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	7.214
Cytochrome P450 2J2	Homo sapiens (human)	3.06
Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)	0.4733
Voltage-dependent L-type calcium channel subunit alpha-1C	Mus musculus (house mouse)	1.2
Voltage-dependent L-type calcium channel subunit alpha-1S	Mus musculus (house mouse)	1.2
Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)	0.035
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	0.0394
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	2.02
Potassium channel subfamily K member 2	Bos taurus (cattle)	8.2
Indoleamine 2,3-dioxygenase 2	Mus musculus (house mouse)	1.5
Voltage-dependent L-type calcium channel subunit alpha-1D	Mus musculus (house mouse)	1.2
Voltage-dependent L-type calcium channel subunit alpha-1F	Mus musculus (house mouse)	1.2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Corradi, L; Fogari, R; Mugellini, A; Pasotti, C; Preti, P; Rinaldi, A; Zoppi, A	1
D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F	1

Trials

2 trial(s) available for telmisartan, hydrochlorothiazide drug combination and nifedipine

Article	Year
Effect of telmisartan/hydrochlorothiazide combination versus nifedipine GITS on ambulatory blood pressure and sympathetic activation. American journal of hypertension, 2005, Volume: 18, Issue:5 Pt 1 Topics: Adult; Aged; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Prospective Studies; Sympathetic Nervous System; Telmisartan	2005
Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus. Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:10 Topics: Adipokines; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glucose Clamp Technique; Humans; Hydrochlorothiazide; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged; Nifedipine; Telmisartan	2015

Article

Year

Effect of telmisartan/hydrochlorothiazide combination versus nifedipine GITS on ambulatory blood pressure and sympathetic activation.

American journal of hypertension, 2005, Volume: 18, Issue:5 Pt 1

Topics: Adult; Aged; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Prospective Studies; Sympathetic Nervous System; Telmisartan

2005

Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus.

Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:10

Topics: Adipokines; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glucose Clamp Technique; Humans; Hydrochlorothiazide; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged; Nifedipine; Telmisartan

2015