telbivudine has been researched along with pyrimidinones in 171 studies
| Studies (telbivudine) | Trials (telbivudine) | Recent Studies (post-2010) (telbivudine) | Studies (pyrimidinones) | Trials (pyrimidinones) | Recent Studies (post-2010) (pyrimidinones) |
|---|---|---|---|---|---|
| 486 | 85 | 332 | 6,059 | 604 | 2,692 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 95 (55.56) | 29.6817 |
| 2010's | 76 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hodge, RA | 1 |
| Lok, AS | 1 |
| Brown, NA; Chao, GC; Lai, CL; Lee, YM; Lim, SG; Lloyd, DM; Myers, MW; Yuen, MF; Zhou, XJ | 1 |
| Han, SH | 1 |
| Brown, NA; Chao, G; Han, S; Hann, HW; Lai, CL; Leung, N; Lloyd, D; Myers, M; Poynard, T; Teo, EK; Tong, M; Wong, F | 1 |
| Lai, CL; Yuen, MF | 1 |
| Brown, NA; Chao, GC; Lloyd, DM; Zhou, XJ | 1 |
| Brown, NA; Chao, GC; Lai, CL; Lim, SG; Lloyd, DM; Zhou, XJ | 1 |
| Kim, JW; Louie, SG; Park, SH | 1 |
| Alcorn, HW; Brown, NA; Chao, GC; Dubuc Patrick, G; Marbury, TC; Smith, WB; Zhou, XJ | 1 |
| Brown, NA; Chao, GC; Fielman, BA; Lloyd, DM; Zhou, XJ | 1 |
| Brown, NA; Chao, GC; Hu, P; Jiang, J; Pietropaolo, K; Wang, H; Zhou, XJ | 1 |
| Jones, R; Nelson, M | 1 |
| Brown, NA; Hu, P; Jiang, J; Shen, K; Wang, HY; Zhou, XJ | 1 |
| Lu, ZM; Xu, J | 1 |
| Gish, RG | 1 |
| Dienstag, J; Easley, C; Kirkpatrick, P | 1 |
| Ruiz-Sancho, A; Sheldon, J; Soriano, V | 1 |
| Hadziyannis, SJ | 1 |
| Chen, CW; Chen, YG; He, YW; Hou, JL; Jia, JD; Ma, H; Niu, JQ; Ren, H; Tan, DM; Wan, MB; Wang, QH; Wang, YM; Wei, L; Wu, SM; Xu, DZ; Xu, JZ; Yin, YK; Zhou, XQ; Zhu, LM | 1 |
| Pham, PA; Thio, C | 1 |
| Garcia-Gasco, P; Sheldon, J; Soriano, V | 1 |
| Keam, SJ | 1 |
| Danta, M; Dusheiko, G | 1 |
| Brown, NA; Chao, GC; Dubuc-Patrick, G; Marbury, TC; Smith, WB; Swan, S; Zhou, XJ | 1 |
| Niederau, C | 1 |
| Brown, NA; Bzowej, N; Chan, HL; Chao, YC; Cho, M; Harb, G; Heathcote, EJ; Jeffers, L; Kaiser, R; Lai, CL; Marcellin, P; Minuk, GY; Moon, YM; Myers, RP; Qiao, XJ; Sievert, W | 1 |
| Hou, JL; Sun, J; Wang, C | 1 |
| Gaeta, GB; Stornaiuolo, G | 1 |
| Alexandre, JA; Deville-Bonne, D; Périgaud, C; Roy, B; Topalis, D | 1 |
| Amarapurkar, DN | 1 |
| Brown, NA; Chao, G; Chen, C; Chen, Y; Constance, BF; Harb, G; He, Y; Hou, J; Jia, J; Niu, J; Ren, H; Tan, D; Wan, M; Wang, Q; Wang, Y; Wei, L; Wu, S; Xu, D; Xu, J; Yin, YK; Zhou, X; Zhu, L | 1 |
| Brown, NA; Bzowej, N; Chao, G; Chen, Y; Constance, BF; Di Bisceglie, AM; Gane, E; Goodman, Z; Heathcote, EJ; Hsu, CW; Lai, CL; Liaw, YF; Moon, YM; Naoumov, NV; Rasenack, J; Thongsawat, S; Wang, Y; Zeuzem, S | 1 |
| Ahn, SH; Cho, M; Choi, HS; Han, JY; Hwang, SG; Kim, BS; Kim, DJ; Kim, YS; Moon, YM; Rim, KS | 1 |
| Matthews, SJ | 1 |
| Hann, HW | 2 |
| Sánchez-Tapias, JM | 1 |
| Goto, T; Kato, N; Omata, M | 1 |
| McHutchison, JG; Tillmann, HL | 1 |
| Mauss, S | 1 |
| Butí, MA | 1 |
| Ayoub, WS; Keeffe, EB | 1 |
| Bridges, EG; Luo, S; Selden, JR | 1 |
| Jin, R; Tao, ML; Zhang, SB; Zhang, XS | 1 |
| Chawla, PS; Kochar, MS | 1 |
| Yim, HJ | 1 |
| Brett, S; Chokshi, S; Cooksley, H; Evans, A; Naoumov, NV; Nathwani, A; Phillips, S; Puranik, S; Riva, A | 1 |
| Chan, HL; Lui, YY | 2 |
| Beckebaum, S; Cicinnati, VR; Gerken, G; Sotiropoulos, GC | 1 |
| Guo, SH; He, H; Ren, H; Shi, KQ; Shi, XF; Wang, ZY; Zeng, WQ; Zhang, DZ | 1 |
| Albanis, E; Brown, NA; Bzowej, N; Cakaloglu, Y; Chen, Y; Galil, K; Gane, E; Han, SH; Heathcote, EJ; Hwang, SG; Lai, CL; Leung, N; Liaw, YF; Manns, M; Naoumov, NV; Niu, J; Papatheodoridis, G; Tong, MJ; Wang, Y; Zeuzem, S | 1 |
| Li, B; Patty, A; Seifer, M; Serra, I; Standring, DN | 1 |
| Hadziyannis, SJ; Vassilopoulos, D | 1 |
| Andersen, ES; Weis, NM | 1 |
| García Buey, L; González Mateos, F; Moreno Otero, R | 1 |
| Buti, M | 1 |
| González-Diéguez, ML; Rodríguez, M | 1 |
| Barreiro, P; García-Samaniego, J; Martín-Carbonero, L | 1 |
| Chen, M; Pan, XC; Yang, F | 1 |
| Fontana, RJ | 1 |
| Chien, RN; Liaw, YF | 1 |
| Buster, EH; Janssen, HL; Schalm, SW | 1 |
| Han, T; Liang, J; Xiao, SX | 1 |
| Colombo, M; Lampertico, P | 1 |
| Nash, K | 1 |
| Keeffe, EB; Nguyen, MH | 1 |
| Atkins, M; Cox, A; Low, E; Nelson, M | 1 |
| Amini-Bavil-Olyaee, S; Herbers, U; Luedde, T; Sheldon, J; Tacke, F; Trautwein, C | 1 |
| Liaw, YF | 1 |
| Iun', F | 1 |
| Chen, M; Guo, SH; He, H; Zhang, DZ; Zhang, L | 1 |
| Dusheiko, GM; Jacobs, MG | 1 |
| Bao, W; Belanger, B; Buti, M; Chutaputti, A; DiBisceglie, A; Gane, E; Hou, J; Jia, J; Liaw, YF; Lim, SG; Naoumov, NV; Nguyen, TT; O'Brien, C; Poynard, T; Rasenack, J; Zeuzem, S | 1 |
| Borroto-Esoda, K; Curtis, M; Miller, MD; Qi, X; Zhu, Y | 1 |
| Farrell, C; Ke, J; Mayers, DL; Pentikis, HS; Sallas, WM; Zhou, XJ | 1 |
| Janssen, HL; Reijnders, JG | 1 |
| ZHUANG, H | 1 |
| Cong, M; Jia, J; Li, H; Liu, T; Ma, H; Ou, X; Ren, J; Wang, B; Wang, P; Wang, X; You, H | 1 |
| Fleischer, RD; Lok, AS | 1 |
| Wang, L; Zhang, LJ | 1 |
| Chen, W; Hou, JL | 1 |
| Barreiro, P; Fernández, JV; Labarga, P; Medrano, J; Soriano, V; Tuma, P; Vispo, E | 1 |
| Balotta, C; Caramma, I; Cesari, M; De Maddalena, C; Galli, M; Lai, A; Milazzo, L; Violin, M | 1 |
| Harris, SI; Ke, J; Mayers, D; Poordad, F; Xu, L; Zeldin, G; Zhou, XJ | 1 |
| Cooper, K; Harris, P; Hartwell, D; Jones, J | 1 |
| Lin, Q; Zhang, DZ | 1 |
| Chang, JB; Wang, JF; Xue, R | 1 |
| Avila, C; Bao, W; Herrmann, E; Kim, JH; Lee, HC; Lee, HJ; Lee, MS; Lee, YJ; Lee, YS; Lopez, P; Suh, DJ; Um, SH; Zeuzem, S | 1 |
| Duong, A; Mousa, SA | 1 |
| Chiarenza, A; Di Raimondo, F; Fatuzzo, F; Iacobello, C; La Rosa, R; Larocca, L; Montineri, A; Nigro, L | 1 |
| Marcellin, P; Perrillo, RP | 1 |
| An, B; Bao, S; Cai, W; Gu, R; Guo, Q; Wang, H; Xie, Q; Zhao, G; Zhou, X | 1 |
| Avila, C; Evans, TG; Karwowska, S; Lam, E; Limoli, K; Lin, K | 1 |
| Chan, HL; Han, KH; Hou, JL; Kao, JH; Lui, YY; Mihm, U; Mohamed, R; Piratvisuth, T; Teo, EK; Tsoi, KK; Wong, GL; Wong, VW | 1 |
| Chen, EQ; Dai, J; Gao, Z; Lei, J; Liu, C; Liu, FJ; Liu, L; Tang, H; Xu, L; Zhou, TY | 1 |
| Chee, GM; Poordad, F | 1 |
| Chen, YP; Dai, ZJ; Shi, KQ; Ye, C; Zheng, MH | 1 |
| Guo, HH; Ji, SW; Jiao, J; Li, Y; Siqingtu, NL; Wang, JB; Xu, Y; Zhang, YG; Zhao, P; Zhou, CY | 1 |
| Bao, H; Furman, PA; Korba, B; Micolochick Steuer, HM; Murakami, E; Niu, C; Tolstykh, T | 1 |
| Chien, RN | 1 |
| Chen, H; Li, T; Shen, J; Wu, B | 1 |
| Chen, T; Guo, W; Lu, YL; Luo, XP; Ning, Q; Wang, HW; Wang, XJ; Wu, ZG; Yan, WM; Yang, XJ; Zou, Y | 1 |
| Caprio, N; Coppola, N; Iodice, V; Macera, M; Masiello, A; Pasquale, G; Tonziello, G | 1 |
| But, DY; Fung, J; Lai, CL; Yuen, MF | 1 |
| Jin, X; Lv, GC; Ma, WJ; Yang, YD; Ying, LJ; Zheng, L | 1 |
| Jin, X; Li, L; Lv, G; Ma, WJ; Yang, Y; Ying, L; Zheng, L | 1 |
| Chen, L; Dai, X; Fan, X; Tang, L; Zhao, S; Zhou, R | 1 |
| Gong, HY; Liu, ZG; Zhang, HY; Zhang, Z | 1 |
| Keam, SJ; McKeage, K | 1 |
| Bao, W; Goodman, ZD; Jung, M; Lopez, P; Manns, MP; Naoumov, NV; Riva, A; Wedemeyer, H; Wursthorn, K | 1 |
| Chen, FJ; Chong, YT; Deng, H; Gao, ZL; Lin, BL; Xie, DY; Zhang, XH | 1 |
| Chen, Y; Hwang, SG; Jia, JD; Lopez, P; Safadi, R; Wei, L; Xie, Q; Yin, YK; Zuckerman, E | 1 |
| Ge, SF; Guo, WW; Hu, JG; Jiang, JN; Jiang, ZC; Liang, YX; Liu, ZH; Su, MH; Zhu, MQ | 1 |
| Ay, L; Finsterer, J | 1 |
| Bourlière, M; Kahloun, A; Zoulim, F | 1 |
| Benhamou, Y; Pais, R | 1 |
| Abbott, WG; Hou, JL; Huang, X; Li, C; Li, YY; Ma, SW; Sun, J; Zhang, GW | 1 |
| Fung, J; Hung, IF; Lai, CL; Seto, WK; Wong, DK; Yuen, JC; Yuen, MF | 1 |
| Abuduheilili, X; Dong, JP; Hou, CS; Jiao, XJ; Li, T; Li, XG; Liu, BM; Sun, XW; Wang, YH; Xu, J; Yan, CH; Yan, L; Yang, JX; Zhuang, H | 1 |
| Leung, N | 1 |
| Papatheodoridis, GV | 1 |
| Zoulim, F | 1 |
| Mallet, V; Pol, S; Vallet-Pichard, A | 1 |
| Bai, XF; Gou, YZ; Jiang, W; Liu, B; Yu, HT | 1 |
| Cornberg, M; Darnedde, M; Jaroszewicz, J; Manns, MP; Mederacke, I; Raupach, R; Wedemeyer, H; Wursthorn, K; Zacher, BJ | 1 |
| Cao, H; Chen, LB; Chen, N; Li, G; Shu, X; Xu, QH; Zhang, K; Zhang, YF | 1 |
| Dai, J; Ji, D; Li, L; Li, X; Liu, Y; Ren, X; Wang, C; Wang, L; Wong, VW; Xu, D; Xu, Z; Yao, Z; Zhang, L; Zhong, Y; Zoulim, F | 1 |
| Akarca, US; Yurdaydin, C | 1 |
| Avila, C; Bao, W; Chao, YC; Gane, EJ; Hou, J; Hsu, CW; Jia, J; Leung, N; Liaw, YF; Lopez, P; Moon, YM; Niu, J; Samuel, D; Thongsawat, S; Wan, M; Wang, Y | 1 |
| Cho, YK; Song, BC | 1 |
| Cao, H; Chen, B; Chen, Y; Li, L; Li, X; Pan, X; Wu, W; Yang, X; Ye, B | 1 |
| Cong, M; Jia, J; Liu, T; Ma, H; Ou, X; Wang, B; Wang, P; Wang, Q; Wu, X; You, H | 1 |
| Tornai, I | 1 |
| Chen, R; Chen, WL; Chen, XF; Chen, XP; Huang, J; Luo, XD; Ma, XJ | 1 |
| Dang, S; Gao, N; Jia, X; Zhang, X | 1 |
| Bai, SF; Cao, MK; Fang, ZX; Han, GR; Jiang, HX; Tang, X; Wang, CM; Wang, GJ; Yue, X; Zhao, W | 1 |
| Petersen, J | 1 |
| Chen, CB; Chen, M; Ren, H; Shi, TD; Sun, H; Wang, XF; Zhang, JM | 1 |
| Giles, M; Sasadeusz, J; Visvanathan, K | 1 |
| Razonable, RR | 1 |
| Arends, JE; Beilhartz, GL; de Jong, D; Götte, M; Hoepelman, AI; Nijhuis, M; Obikhod, A; Pingen, M; Schinazi, RF; Tao, S; van Maarseveen, NM; Wensing, AM | 1 |
| Jiang, XQ; Tian, DY; Zou, XJ | 1 |
| Suzuki, F | 2 |
| García-Alonso, FJ; Martín-Mateos, RM; Moreira Vicente, V | 1 |
| Abbott, WG; Dong, YH; Hou, JL; Huang, X; Jiang, XT; Li, YY; Liu, ZH; Ma, SW; Naoumov, NV; Sun, J; Sun, XF; Tang, LB; Zhang, YX | 1 |
| Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Tsai, MC; Tseng, PL; Tung, WC; Wang, JH; Yen, YH | 1 |
| Abbott, WG; Hou, J; Huang, X; Jiang, X; Lai, Q; Li, Y; Ma, S; Sun, J; Zhang, M | 1 |
| Lau, GK; Wang, FS | 1 |
| Bai, XF; Li, Y; Lian, JQ; Nan, XP; Peng, MJ; Su, WJ; Sun, RL; Wang, JP; Yu, HT; Zhang, Y | 1 |
| Fontana, RJ; Singal, AK | 1 |
| Cao, MK; Han, GR; Jiang, HX; Pan, CQ; Wang, CM; Wang, GJ; Yue, X; Zhao, W | 1 |
| Fu, J; Gao, X; Li, L; Liu, M; Pan, X; Yao, W | 1 |
| Fan, XJ; Hu, XY; Liu, GW; Nie, HM; Zhang, Y; Zhong, S | 1 |
| Han, GR; Jiang, HX; Kan, NY; Wang, CM; Wang, GJ; Wu, MM; Yue, X | 1 |
| Dusheiko, G | 1 |
| Jiang, S; Pan, HJ; Zheng, JL; Zhou, YJ | 1 |
| Chen, X; Huang, Z; Mao, Q; Ni, B; Tang, J; Tian, Y; Wang, Q; Wu, Y; Zhang, X; Zhang, Y; Zheng, Y; Zhou, J | 1 |
| Almasio, PL; Bertino, G; Brandolino, N; Bruno, S; Caroleo, B; Cosco, L; Di Marco, V; Foti, G; Frugiuele, P; Galdieri, A; Madonia, S; Montalto, G; Portelli, V; Russello, M; Sapienza, M; Scifo, G; Siciliano, R; Spadaro, A; Stroffolini, T; Surace, L | 1 |
| Bai, L; Chen, EQ; Liang, LB; Tang, H; Wang, JR; Yan, LB; Zhou, TY | 1 |
| Avila, C; Bao, W; Chan, HL; Chen, YC; Choudhuri, G; Chutaputti, A; Gane, EJ; Hwang, SG; Piratvisuth, T; Prabhakar, B; Safadi, R; Sarin, SK; Suh, DJ; Tanwandee, T; Trylesinski, A; Yurdaydin, C | 1 |
| Amato, G; Calise, F; Cuomo, O; Dicostanzo, G; Lanza, AG; Marcos, A; Perrella, A; Pisaniello, D; Santaniello, W | 1 |
55 review(s) available for telbivudine and pyrimidinones
| Article | Year |
|---|---|
Telbivudine/Torcitabine Idenix/Novartis.
Topics: Animals; Antiviral Agents; Clinical Trials as Topic; Drugs, Investigational; Hepatitis B; Hepatitis B virus; Humans; Nucleosides; Pyrimidinones; Technology, Pharmaceutical; Telbivudine; Thymidine | 2004 |
New treatment of chronic hepatitis B.
Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2004 |
Telbivudine: a new nucleoside analogue for the treatment of chronic hepatitis B.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2005 |
Telbivudine: an upcoming agent for chronic hepatitis B.
Topics: Antiviral Agents; DNA, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Molecular Structure; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2005 |
Telbivudine: a novel nucleoside analog for chronic hepatitis B.
Topics: Animals; Antiviral Agents; Clinical Trials as Topic; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2006 |
Novel anti-hepatitis B agents: A focus on telbivudine.
Topics: Antiviral Agents; Clinical Trials, Phase II as Topic; DNA, Viral; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Viral Core Proteins | 2006 |
[Progress in the treatment of chronic hepatitis B with Telbivudine].
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2006 |
Improving outcomes for patients with chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2007 |
Telbivudine: a new option for the treatment of chronic hepatitis B.
Topics: Animals; Antiviral Agents; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2007 |
Treatment paradigms on hepatitis B e antigen-negative chronic hepatitis B patients.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Treatment of chronic hepatitis B in HIV-infected patients in 2007.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2007 |
Telbivudine.
Topics: Antiviral Agents; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleic Acid Synthesis Inhibitors; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Telbivudine for the treatment of chronic hepatitis B.
Topics: Antiviral Agents; Clinical Trials as Topic; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2007 |
Therapy of chronic hepatitis B: focus on telbivudine.
Topics: Alanine Transaminase; Antiviral Agents; DNA, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Viral Load | 2007 |
Telbivudine: a new treatment for chronic hepatitis B.
Topics: Antiviral Agents; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Hepatitis B, Chronic; Humans; India; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Telbivudine for the management of chronic hepatitis B virus infection.
Topics: Alanine Transaminase; Antiviral Agents; Clinical Trials as Topic; DNA, Viral; Drug Interactions; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Molecular Structure; Nucleosides; Pyrimidinones; Salvage Therapy; Telbivudine; Thymidine | 2007 |
Active antiviral therapy for chronic hepatitis B and hepatocellular carcinoma.
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver Neoplasms; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2008 |
[Pharmacological agents for the treatment of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2008 |
Clinical implications of resistance patterns against HBV-polymerase inhibitors for the treatment of chronic hepatitis B.
Topics: Adenine; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2007 |
[Telbivudine in the treatment of the chronic B hepatitis].
Topics: Adolescent; Adult; Aged; Antiviral Agents; Biomarkers, Pharmacological; Biotransformation; Clinical Trials, Phase III as Topic; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Muscular Diseases; Nucleosides; Phosphorylation; Prodrugs; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Virus Replication | 2008 |
Review article: current antiviral therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
What's new in clinical pharmacology and therapeutics.
Topics: Abatacept; Acetanilides; Amides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiparkinson Agents; Antirheumatic Agents; Antiviral Agents; Apomorphine; Benzazepines; Cardiovascular Agents; Fumarates; Hepatitis B; Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; Humans; Hypoglycemic Agents; Immunoconjugates; Multiple Sclerosis; Natalizumab; Nucleosides; Papillomavirus Vaccines; Pharmacology, Clinical; Piperazines; Pyrazines; Pyrimidinones; Quinoxalines; Ranolazine; Sitagliptin Phosphate; Smoking Cessation; Telbivudine; Thymidine; Triazoles; Varenicline; Viral Vaccines | 2008 |
[Management of antiviral-resistant chronic hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2008 |
A review of telbivudine for the management of chronic hepatitis B virus infection.
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine | 2008 |
Hepatitis B and liver transplantation: 2008 update.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B Vaccines; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2009 |
Telbivudine in the treatment of chronic hepatitis B.
Topics: Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2008 |
[Interferon in hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome | 2008 |
[Nucleoside and nucleotide analogs in the treatment of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2008 |
[Clinical management of patients with chronic hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Biopsy; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genotype; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Liver; Liver Transplantation; Male; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
[Hepatitis B in patients with HIV infection].
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success.
Topics: Adenine; Adenine Nucleotides; Alanine Transaminase; Carcinoma, Hepatocellular; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2008 |
Peginterferon for the treatment of chronic hepatitis B in the era of nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2008 |
HBeAg-negative chronic hepatitis B: why do I treat my patients with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2009 |
Telbivudine in the treatment of chronic hepatitis B.
Topics: Alanine Transaminase; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; DNA, Viral; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Safety; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2009 |
Chronic hepatitis B: early viral suppression and long-term outcomes of therapy with oral nucleos(t)ides.
Topics: Adenine; Administration, Oral; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2009 |
On-treatment outcome prediction and adjustment during chronic hepatitis B therapy: now and future.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; DNA, Viral; Drug Resistance, Multiple, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Medication Adherence; Nucleosides; Organophosphonates; Polyethylene Glycols; Prognosis; Pyrimidinones; Recombinant Proteins; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2009 |
Treatment of chronic hepatitis B: focus on telbivudine.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleic Acid Synthesis Inhibitors; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2009 |
Myopathy and neuropathy associated with nucleos(t)ide analog therapy for hepatitis B.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; Drug Discovery; Early Termination of Clinical Trials; Hepatitis B, Chronic; Humans; Lamivudine; Mitochondrial Myopathies; Muscular Diseases; Nervous System Diseases; Nucleosides; Nucleotides; Pyrimidinones; Republic of Korea; Telbivudine; Thymidine | 2009 |
Telbivudine for the treatment of chronic hepatitis B infection.
Topics: Adult; Antiviral Agents; Cost-Benefit Analysis; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Current status of nucleoside antivirals in chronic hepatitis B.
Topics: Antiviral Agents; Cost-Benefit Analysis; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Effect of newer oral antiviral agents on future therapy of chronic hepatitis B.
Topics: Adenine; Administration, Oral; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2010 |
On-treatment monitoring of chronic hepatitis B virus infection: an Asian-Pacific perspective.
Topics: Adenine; Antiviral Agents; Asia; Biomarkers; DNA, Viral; Drug Monitoring; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2010 |
Safety evaluation of telbivudine.
Topics: Adult; Antiviral Agents; Biomarkers; Creatine Kinase; Double-Blind Method; Drug Resistance, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Isoenzymes; Male; Multicenter Studies as Topic; Muscular Diseases; Nucleosides; Peripheral Nervous System Diseases; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine | 2010 |
Telbivudine: an effective anti-HBV drug for chronic hepatitis B patients with early on-treatment responses.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2010 |
Comparison of the efficacy of lamivudine and telbivudine in the treatment of chronic hepatitis B: a systematic review.
Topics: Antiviral Agents; Clinical Trials as Topic; Databases, Factual; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2010 |
Telbivudine: a review of its use in compensated chronic hepatitis B.
Topics: Antiviral Agents; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2010 |
Treatment of HBeAg-positive chronic hepatitis B with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2011 |
Hepatitis B virus resistance to antiviral drugs: where are we going?
Topics: Adenine; Antiviral Agents; Capsid; Clinical Protocols; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Internalization; Virus Replication | 2011 |
The impact of human immunodeficiency virus on viral hepatitis.
Topics: Adenine; Antiviral Agents; Deoxycytidine; Disease Progression; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis C; Hepatitis Viruses; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
[Interferon-based versus direct antiviral therapy in patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2011 |
Antiviral therapy for hepatitis B infection during pregnancy and breastfeeding.
Topics: Adenine; Antiviral Agents; Breast Feeding; Female; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
Antiviral drugs for viruses other than human immunodeficiency virus.
Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir | 2011 |
[Pharmacological treatment of acute hepatitis B].
Topics: Acute Disease; Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Spain; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2012 |
Meta-analysis: oral anti-viral agents in adults with decompensated hepatitis B virus cirrhosis.
Topics: Adenine; Administration, Oral; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2012 |
[New drugs of treatment of patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2012 |
40 trial(s) available for telbivudine and pyrimidinones
| Article | Year |
|---|---|
A dose-finding study of once-daily oral telbivudine in HBeAg-positive patients with chronic hepatitis B virus infection.
Topics: Adult; Aged; DNA, Viral; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2004 |
A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B.
Topics: Adolescent; Adult; Age Factors; Aged; DNA, Viral; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Long-Term Care; Male; Maximum Tolerated Dose; Middle Aged; Nucleosides; Pyrimidinones; Reference Values; Risk Assessment; Severity of Illness Index; Sex Factors; Telbivudine; Thymidine; Treatment Outcome | 2005 |
Absence of food effect on the pharmacokinetics of telbivudine following oral administration in healthy subjects.
Topics: Absorption; Administration, Oral; Adult; Antiviral Agents; Area Under Curve; Cross-Over Studies; Dietary Fats; Drug Monitoring; Energy Intake; Fasting; Female; Food; Food-Drug Interactions; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2006 |
Pharmacokinetics of telbivudine following oral administration of escalating single and multiple doses in patients with chronic hepatitis B virus infection: pharmacodynamic implications.
Topics: Administration, Oral; Adult; Antiviral Agents; Area Under Curve; Asian People; China; Cohort Studies; DNA, Viral; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Half-Life; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2006 |
Pharmacokinetics of telbivudine in subjects with various degrees of hepatic impairment.
Topics: Administration, Oral; Antiviral Agents; Area Under Curve; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Liver Diseases; Male; Mass Spectrometry; Middle Aged; Nucleosides; Pyrimidinones; Severity of Illness Index; Telbivudine; Thymidine | 2006 |
Pharmacokinetics of telbivudine in healthy subjects and absence of drug interaction with lamivudine or adefovir dipivoxil.
Topics: Adenine; Administration, Oral; Adult; Anti-HIV Agents; Antiviral Agents; Area Under Curve; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2006 |
Single-dose and multiple-dose pharmacokinetics and safety of telbivudine after oral administration in healthy Chinese subjects.
Topics: Administration, Oral; Adult; China; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Health; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2006 |
[Study on the pharmacokinetic profile of telbivudine].
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Female; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Young Adult | 2006 |
[The degree of HBV suppression with 24 week telbivudine- or lamivudine-treatment in hepatitis B patients predicts the efficacy of the treatment at week 52].
Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Double-Blind Method; Female; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2007 |
Pharmacokinetics of telbivudine in subjects with various degrees of renal impairment.
Topics: Adolescent; Adult; Aged; Female; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial.
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine; Viral Load | 2007 |
Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial.
Topics: Adolescent; Adult; Antiviral Agents; China; DNA, Viral; Double-Blind Method; Female; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2008 |
Telbivudine versus lamivudine in patients with chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Double-Blind Method; Drug Resistance, Viral; Female; Genotype; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
[The efficacy and safety of telbivudine in korean patients with chronic hepatitis B].
Topics: Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Korea; Lamivudine; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2007 |
[Short-term results of telbivudine versus entecavir treatments in HBeAg-positive chronic hepatitis B patients in China].
Topics: Adolescent; Adult; Aged; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Viral Load; Young Adult | 2008 |
2-Year GLOBE trial results: telbivudine Is superior to lamivudine in patients with chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Double-Blind Method; Female; Global Health; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nucleosides; Prospective Studies; Pyrimidinones; Regression Analysis; Telbivudine; Thymidine; Treatment Outcome; Virus Replication; Young Adult | 2009 |
[Telbivudine treatment on cirrhosis resulting from chronic hepatitis B].
Topics: Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2009 |
Baseline characteristics and early on-treatment response predict the outcomes of 2 years of telbivudine treatment of chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2009 |
[Blocking intrauterine infection by telbivudine in pregnant chronic hepatitis B patients].
Topics: Administration, Oral; Antiviral Agents; DNA, Viral; Female; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2009 |
Absence of effect of telbivudine on cardiac repolarization: results of a thorough QT/QTc study in healthy participants.
Topics: Adult; Antiviral Agents; Area Under Curve; Body Mass Index; Cross-Over Studies; Electrocardiography; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Sex Characteristics; Statistics as Topic; Telbivudine; Thymidine; Young Adult | 2009 |
Early viral kinetics of telbivudine and entecavir: results of a 12-week randomized exploratory study with patients with HBeAg-positive chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kinetics; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2010 |
A 24-week, parallel-group, open-label, randomized clinical trial comparing the early antiviral efficacy of telbivudine and entecavir in the treatment of hepatitis B e antigen-positive chronic hepatitis B virus infection in adult Chinese patients.
Topics: Adult; Antiviral Agents; China; DNA, Viral; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2010 |
[Clinical antiviral effects of telbivudine in patients with chronic hepatitis B].
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2010 |
Efficacy of telbivudine in HBeAg-positive chronic hepatitis B patients with high baseline ALT levels.
Topics: Alanine Transaminase; Antiviral Agents; DNA, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2010 |
[Analysis of the prophylactic effect of nucleosides against reactivation of HBV in HBsAg-positive patients with non-hepatic tumors after chemotherapy].
Topics: Adult; Antineoplastic Agents; Antiviral Agents; Breast Neoplasms; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Lung Neoplasms; Lymphoma; Male; Middle Aged; Nucleosides; Pyrimidinones; Retrospective Studies; Telbivudine; Thymidine; Virus Activation | 2010 |
Efficacy of switching to telbivudine in chronic hepatitis B patients treated previously with lamivudine.
Topics: Adult; Antiviral Agents; Biomarkers; Chi-Square Distribution; DNA, Viral; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Viral; Drug Substitution; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2011 |
Complementarity-determining region 3 size spectratypes of T cell receptor beta chains in CD8+ T cells following antiviral treatment of chronic hepatitis B.
Topics: Adult; Antiviral Agents; CD8-Positive T-Lymphocytes; Complementarity Determining Regions; Double-Blind Method; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Lymphocyte Activation; Male; Nucleosides; Polymerase Chain Reaction; Pyrimidinones; Receptors, Antigen, T-Cell, alpha-beta; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2011 |
The diagnostic value of ultrasound elastography in patients with hepatitis B virus infection: a prospective study.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; Asian People; China; Demography; Elasticity; Elasticity Imaging Techniques; Female; Hepatitis B; Hepatitis B virus; Humans; Hyaluronic Acid; Liver Cirrhosis; Male; Middle Aged; Nucleosides; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine; Young Adult | 2010 |
[Efficacy of antiviral treatment on patients with acute-on-chronic hepatitis B liver failure with low viral load].
Topics: Adult; Antiviral Agents; End Stage Liver Disease; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Failure, Acute; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Viral Load | 2010 |
Efficacy and safety of prolonged 3-year telbivudine treatment in patients with chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; Biomarkers; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Young Adult | 2011 |
[Study on the efficacy and HBeAg seroconversion related factors of telbivudine and entecavir therapy in HBeAg positive chronic hepatitis B patients].
Topics: Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2011 |
A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection.
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2011 |
High serum IL-21 levels after 12 weeks of antiviral therapy predict HBeAg seroconversion in chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; Disease Progression; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interleukins; Male; Nucleosides; Pyrimidinones; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Telbivudine; Thymidine; Treatment Outcome | 2012 |
Inhibition of viral replication downregulates CD4(+)CD25(high) regulatory T cells and programmed death-ligand 1 in chronic hepatitis B.
Topics: Adult; Antiviral Agents; B7-H1 Antigen; CD4-Positive T-Lymphocytes; Cytokines; Down-Regulation; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interleukin-2 Receptor alpha Subunit; Interleukin-9; Lymphocyte Count; Male; Nucleosides; Pyrimidinones; T-Lymphocytes, Regulatory; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Virus Replication | 2012 |
Telbivudine prevents vertical transmission from HBeAg-positive women with chronic hepatitis B.
Topics: Adult; Antiviral Agents; Case-Control Studies; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Incidence; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine | 2012 |
[Influences of warming kidney prescription on antiviral therapeutic efficacy and creatine kinase in telbivudine-treated HBeAg-positive chronic hepatitis B patients].
Topics: Adult; Antiviral Agents; Creatine Kinase; Female; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Phytotherapy; Pyrimidinones; Telbivudine; Thymidine | 2012 |
[Efficacy and safety of telbivudine in pregnant women to prevent perinatal transmission of hepatitis B virus].
Topics: Adult; DNA, Viral; Female; Hepatitis B; Hepatitis B virus; Humans; Infectious Disease Transmission, Vertical; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Pyrimidinones; Telbivudine; Thymidine; Viral Load; Young Adult | 2012 |
[Efficacy and safety of telbivudine in pregnant chronic hepatitis B patients].
Topics: Adult; Antiviral Agents; Female; Hepatitis B, Chronic; Humans; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2011 |
Lamivudine plus adefovir or telbivudine plus adefovir for chronic hepatitis B patients with suboptimal response to adefovir.
Topics: Adenine; Adult; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Nucleosides; Organophosphonates; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2012 |
Randomized clinical trial: efficacy and safety of telbivudine and lamivudine in treatment-naïve patients with HBV-related decompensated cirrhosis.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Double-Blind Method; Female; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Failure; Male; Middle Aged; Multicenter Studies as Topic; Nucleosides; Prospective Studies; Pyrimidinones; Severity of Illness Index; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2012 |
76 other study(ies) available for telbivudine and pyrimidinones
| Article | Year |
|---|---|
Telbivudine (Tyzeka) for chronic Hepatitis B.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Telbivudine.
Topics: Antiviral Agents; Enzyme Inhibitors; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine | 2007 |
Drug profile: telbivudine (Tyzeka).
Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Treatment Outcome | 2007 |
[New first line therapy of chronic hepatitis B. Primary therapy goal: effective virus suppression].
Topics: Antiviral Agents; Clinical Trials as Topic; DNA, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2007 |
[Treatment in every detected virus replication. New guideline for therapy of hepatitis B publicized].
Topics: Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Nucleosides; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2007 |
[New German and American guidelines for therapy of hepatitis B. Discrepancies and similarities].
Topics: Adenine; Alanine Transaminase; Antiviral Agents; Biopsy; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Germany; Guanine; Hepatitis B; Humans; Lamivudine; Liver; Liver Cirrhosis; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; United States | 2007 |
Summaries for patients. Antiviral therapy for chronic hepatitis B.
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine; Viral Load | 2007 |
[Several important issues on drug resistance of hepatitis B virus].
Topics: Antiviral Agents; Drug Resistance, Viral; Hepatitis B; Hepatitis B virus; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Enantio-selectivity of human nucleoside monophosphate kinases.
Topics: Antiviral Agents; Humans; Nucleoside-Phosphate Kinase; Nucleosides; Pyrimidine Nucleosides; Pyrimidinones; Stereoisomerism; Telbivudine; Thymidine | 2007 |
[Anti-viral therapy of type B chronic hepatitis. 3. Future of anti-viral agents].
Topics: Adenine; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Hepatitis B, Chronic; Humans; Interferons; Nucleic Acid Synthesis Inhibitors; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2008 |
Telbivudine versus lamivudine in patients with chronic hepatitis B.
Topics: Antiviral Agents; Drug Resistance, Viral; Genotype; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Viral Load | 2008 |
Nonclinical safety profile of telbivudine, a novel potent antiviral agent for treatment of hepatitis B.
Topics: Administration, Oral; Animals; Antiviral Agents; Carcinogenicity Tests; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Tolerance; Female; Hepatitis B, Chronic; Humans; Macaca fascicularis; Male; Mice; Mice, Transgenic; Mutagenicity Tests; Nerve Degeneration; Nucleosides; Pregnancy; Pyrimidinones; Rabbits; Rats; Rats, Sprague-Dawley; Reproduction; Safety; Telbivudine; Thymidine | 2008 |
[Chinese roadmap for treating chronic hepatitis B with telbivudine].
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2008 |
Clinical features of adverse reactions associated with telbivudine.
Topics: Adult; Arrhythmias, Cardiac; Creatine Kinase; Drug Synergism; Hepatitis B, Chronic; Humans; Interferons; Male; Middle Aged; Muscle Weakness; Neuralgia; Nucleosides; Pyrimidinones; Retrospective Studies; Risk Factors; Telbivudine; Thymidine | 2008 |
Programmed death 1 expression during antiviral treatment of chronic hepatitis B: Impact of hepatitis B e-antigen seroconversion.
Topics: Adult; Alanine Transaminase; Antigens, CD; Antiviral Agents; Apoptosis Regulatory Proteins; Biopsy; CD8-Positive T-Lymphocytes; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-gamma; Interleukin-10; Lamivudine; Liver; Longitudinal Studies; Male; Middle Aged; Nucleosides; Programmed Cell Death 1 Receptor; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Viremia | 2008 |
Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir.
Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Gene Products, pol; Hepatitis B virus; Humans; Microbial Sensitivity Tests; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2009 |
[New treatment of chronic hepatitis B].
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2008 |
[The effect of telbivudine on peripheral blood CD4+CD25+ regulatory T cells and its significance in patients with chronic hepatitis B].
Topics: Adolescent; Adult; Antiviral Agents; Case-Control Studies; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interleukin-2 Receptor alpha Subunit; Middle Aged; Nucleosides; Pyrimidinones; T-Lymphocytes, Regulatory; Telbivudine; Thymidine; Young Adult | 2008 |
Hepatitis B: a "GLOBAL" health challenge.
Topics: Antiviral Agents; DNA, Viral; Global Health; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Nucleosides; Patient Selection; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Virus Replication | 2009 |
Telbivudine has activity against HIV-1.
Topics: Anti-HIV Agents; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains.
Topics: Adenine; Anti-HIV Agents; Cell Line, Tumor; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Viral Proteins; Virus Replication | 2009 |
[Methodical recommendations of Asian-Pacific Association for Studying the Liver (APASL) concerning treatment of the viral hepatitis B (HBV)].
Topics: Antiviral Agents; Asia; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Function Tests; Nucleosides; Pacific Islands; Practice Guidelines as Topic; Pyrimidinones; Recombinant Proteins; Severity of Illness Index; Telbivudine; Thymidine | 2008 |
[Dynamic changes of Th1/Th2 type cytokines in peripheral blood of patients with hepatitis B e antigen-positive chronic hepatitis B treated with telbivudine].
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Flow Cytometry; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-gamma; Interleukins; Male; Nucleosides; Pyrimidinones; Telbivudine; Th1 Cells; Th2 Cells; Thymidine; Time Factors; Tumor Necrosis Factor-alpha; Young Adult | 2009 |
Perspectives on the management of chronic hepatitis B and C.
Topics: Antiviral Agents; Enzyme Inhibitors; Hepacivirus; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Immunoglobulins; Interferons; Mental Disorders; Nucleosides; Pyrimidinones; Substance-Related Disorders; Telbivudine; Thymidine | 2009 |
Anti-hepatitis B virus activity in vitro of combinations of tenofovir with nucleoside/nucleotide analogues.
Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2009 |
Population pharmacokinetics of telbivudine and determination of dose adjustment for patients with renal impairment.
Topics: Adult; Aged; Antiviral Agents; Biological Availability; Female; Humans; Kidney Diseases; Male; Middle Aged; Models, Biological; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Treatment with nucleos(t)ide analogues in chronic hepatitis B: where does the road map lead us?
Topics: Antiviral Agents; DNA, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
[Symposium on clinical application of telbivudine].
Topics: Antiviral Agents; Congresses as Topic; DNA, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleosides; Patient Compliance; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Different models of HBeAg seroconversion predicated by on-treatment ALT and HBV DNA profiles.
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Prognosis; Pyrimidinones; Retrospective Studies; Telbivudine; Thymidine; Young Adult | 2009 |
[Pharmacoeconomic evaluation of telbivudine vs. lamivudine in treating the patients with HBeAg-positive and negative chronic hepatitis B].
Topics: Adult; Antifungal Agents; China; Cost-Benefit Analysis; DNA, Viral; Drug Costs; Economics, Pharmaceutical; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Insurance, Long-Term Care; Lamivudine; Liver Cirrhosis; Male; Markov Chains; Middle Aged; Models, Economic; Nucleosides; Prescription Drugs; Pyrimidinones; Quality-Adjusted Life Years; Telbivudine; Thymidine | 2009 |
Hepatitis B in HIV patients: what is the current treatment and what are the challenges?
Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Transaminases | 2009 |
[Telbivudine in the management of HIV/HBV coinfection. Treating hepatitis B without HIV trouble].
Topics: Adenine; AIDS-Related Opportunistic Infections; Algorithms; Anti-HIV Agents; Antiviral Agents; Comorbidity; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Function Tests; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Telbivudine in the treatment of chronic hepatitis B: experience in HIV type-1-infected patients naive for antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Antiviral Agents; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
[The efficacy of nucleoside/nucleotide analogue on chronic hepatitis B].
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2009 |
[Preliminary clinical study of efficacy on re-treatment for interferon suboptimal CHB patients].
Topics: Administration, Oral; Adult; Alanine Transaminase; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferons; Male; Nucleosides; Pyrimidinones; Retreatment; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2009 |
Telbivudine use in a patient affected by occult hepatitis B virus and B-cell non-Hodgkin lymphoma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Biomarkers, Tumor; Cyclophosphamide; DNA; Hepatitis B; Hepatitis B virus; Humans; Lymphoma, B-Cell; Male; Middle Aged; Nucleosides; Prednisolone; Proto-Oncogene Proteins c-bcl-2; Pyrimidinones; Rituximab; Telbivudine; Thymidine; Vincristine | 2010 |
On-treatment serum HBsAg level is predictive of sustained off-treatment virologic response to telbivudine in HBeAg-positive chronic hepatitis B patients.
Topics: Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Multivariate Analysis; Nucleosides; Predictive Value of Tests; Pyrimidinones; ROC Curve; Statistics, Nonparametric; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2010 |
Telbivudine exhibits no inhibitory activity against HIV-1 clinical isolates in vitro.
Topics: Anti-HIV Agents; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2010 |
Cost-effectiveness analysis of roadmap models in chronic hepatitis B using tenofovir as the rescue therapy.
Topics: Adenine; Antiviral Agents; Asia; Cost-Benefit Analysis; Decision Support Techniques; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Germany; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Models, Economic; Nucleosides; Organophosphonates; Pyrimidinones; Salvage Therapy; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; United States | 2010 |
Application of hepatitis B virus replication mouse model.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Drug Resistance, Viral; Enzyme-Linked Immunosorbent Assay; Hepatitis B; Hepatitis B virus; Humans; Liver; Male; Mice; Mice, Inbred BALB C; Mutation; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2010 |
Viral resistance in hepatitis B: prevalence and management.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genetic Testing; Genotype; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Phenotype; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2010 |
Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/nucleotide inhibitors.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cells, Cultured; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Microbial Sensitivity Tests; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2010 |
Cost-effectiveness of nucleoside analog therapy for hepatitis B in China: a Markov analysis.
Topics: Adenine; Antiviral Agents; China; Cost-Benefit Analysis; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Models, Economic; Models, Statistical; Monte Carlo Method; Nucleosides; Organophosphonates; Pyrimidinones; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; Serologic Tests; Telbivudine; Thymidine | 2010 |
Telbivudine preserves T-helper 1 cytokine production and downregulates programmed death ligand 1 in a mouse model of viral hepatitis.
Topics: Animals; Antiviral Agents; B7-H1 Antigen; Cells, Cultured; Cytokines; Female; Hepatitis, Viral, Animal; Immunologic Factors; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Murine hepatitis virus; Nucleosides; Pyrimidinones; Survival Analysis; Telbivudine; Th1 Cells; Thymidine | 2010 |
[Icteric hepatitis in a patient with non-Hodgkin's lymphoma treated by rituximab-based chemotherapy].
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Cyclophosphamide; Cytomegalovirus; Cytomegalovirus Infections; Doxorubicin; Hepatitis B virus; Hepatitis B, Chronic; Humans; Hyperbilirubinemia; Immunocompromised Host; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Nucleosides; Prednisone; Pyrimidinones; Rituximab; Telbivudine; Thymidine; Vincristine; Viremia; Virus Activation | 2010 |
Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment.
Topics: Adult; Antiviral Agents; CD8-Positive T-Lymphocytes; DNA, Viral; Female; Gene Expression Profiling; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunologic Memory; Interleukin-7 Receptor alpha Subunit; Male; Nucleosides; Pyrimidinones; T-Lymphocyte Subsets; Telbivudine; Thymidine | 2010 |
Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients.
Topics: Adult; Antiviral Agents; Body Weight; Enzyme-Linked Immunosorbent Assay; Genotype; Hepatitis B Core Antigens; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Kinetics; Liver; Lymphocyte Activation; Nucleosides; Patient Selection; Pyrimidinones; Racial Groups; T-Lymphocytes; Telbivudine; Thymidine; Time Factors | 2010 |
Telbivudine: rhabdomyolysis and neuropathy.
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Nucleosides; Peripheral Nervous System Diseases; Pyrimidinones; Rhabdomyolysis; Telbivudine; Thymidine | 2010 |
[Programmed death-1 (PD-1) and PD-L1 expression during antiviral treatment of chronic hepatitis B].
Topics: Adult; Antiviral Agents; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Nucleosides; Programmed Cell Death 1 Receptor; Pyrimidinones; Telbivudine; Thymidine; Young Adult | 2010 |
[A study on the factors correlated to virological response in chronic hepatitis B patients with telbivudine treatment].
Topics: Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Young Adult | 2010 |
Myotoxicity of telbivudine in pre-existing muscle damage.
Topics: Adult; Antiviral Agents; Creatine Kinase; Hepatitis B; Humans; Male; Muscle, Skeletal; Muscular Diseases; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2010 |
[Analogs combination therapy in chronic hepatitis B: when and how?].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2010 |
[Long-term therapy for chronic hepatitis B in HIV co-infected patients].
Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine | 2010 |
Significance of HBV DNA levels at 12 weeks of telbivudine treatment and the 3 years treatment outcome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Nucleosides; Predictive Value of Tests; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Young Adult | 2011 |
Profile of HBV antiviral resistance mutations with distinct evolutionary pathways against nucleoside/nucleotide analogue treatment among Chinese chronic hepatitis B patients.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; China; Cross-Sectional Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Molecular Typing; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Young Adult | 2010 |
Treatment of HBeAg-negative chronic hepatitis B patients with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome | 2011 |
Correlation between the Elecsys HBsAg II assay and the Architect assay for the quantification of hepatitis B surface antigen (HBsAg) in the serum.
Topics: Clinical Laboratory Techniques; Drug Resistance, Viral; Genotype; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunoassay; Lamivudine; Longitudinal Studies; Mutation; Nucleosides; Pyrimidinones; Reagent Kits, Diagnostic; Telbivudine; Thymidine | 2011 |
Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection.
Topics: Adenine; Adult; Amino Acid Substitution; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Thymidine; Viral Proteins | 2011 |
Treatment of chronic hepatitis B with telbivudine: wise hepatologists needed in hepatitis B endemic countries where treatment options are limited.
Topics: Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, Viral; Drug Substitution; Endemic Diseases; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2011 |
[New insight for HBV DNA and HBsAg quantitation during antiviral therapy in patients with chronic hepatitis B].
Topics: Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2011 |
Effect of telbivudine therapy on the cellular immune response in chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Cytokines; DNA, Viral; Enzyme-Linked Immunospot Assay; Female; Hepatitis B Core Antigens; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunity, Cellular; Liver; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2011 |
Two patterns of alanine aminotransferase increase to predict long-term viral response in chronic hepatitis B patients: virus- or host-induced?
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepacivirus; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-gamma; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Predictive Value of Tests; Pyrimidinones; T-Lymphocytes; Telbivudine; Thymidine; Treatment Outcome; Up-Regulation; Young Adult | 2011 |
Rhabdomyolysis in a 48-year-old man with hepatitis B-induced cirrhosis.
Topics: Acute Kidney Injury; Antiviral Agents; Fatal Outcome; Fibrosis; Hepatitis B; Humans; Male; Middle Aged; Muscular Diseases; Nucleosides; Pyrimidinones; Rhabdomyolysis; Telbivudine; Thymidine; Treatment Outcome | 2011 |
HBV treatment and pregnancy.
Topics: Female; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Male; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Thymidine | 2011 |
Effects of antiviral therapy with Telbivudine on peripheral iNKT cells in HBeAg(+) chronic hepatitis B patients.
Topics: Adult; Antiviral Agents; Female; Gene Expression Profiling; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Immunologic Factors; Interferon-gamma; Male; Middle Aged; Natural Killer T-Cells; Nucleosides; Programmed Cell Death 1 Receptor; Pyrimidinones; Telbivudine; Thymidine | 2012 |
Telbivudine exerts no antiviral activity against HIV-1 in vitro and in humans.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Cell Line; Coinfection; DNA, Viral; Drug Resistance, Viral; Genotype; HEK293 Cells; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nucleosides; Phenotype; Pyrimidinones; RNA, Viral; Telbivudine; Thymidine; Viral Load | 2011 |
Clinical features and risk factors of creatine kinase elevations and myopathy associated with telbivudine.
Topics: Adolescent; Adult; Age Distribution; Aged; Antiviral Agents; Creatine Kinase; Female; Hepatitis B, Chronic; Humans; Incidence; Male; Middle Aged; Muscular Diseases; Nucleosides; Pyrimidinones; Risk Factors; Sex Distribution; Telbivudine; Thymidine; Young Adult | 2011 |
[New drugs of treatment of patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
A comparison of telbivudine and entecavir for chronic hepatitis B in real-world clinical practice.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2012 |
Restored circulating invariant NKT cells are associated with viral control in patients with chronic hepatitis B.
Topics: Adult; Case-Control Studies; CD4-Positive T-Lymphocytes; Cell Movement; Cytokines; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Natural Killer T-Cells; Nucleosides; Pyrimidinones; Receptors, CCR5; Receptors, CCR6; Telbivudine; Thymidine; Young Adult | 2011 |
Uncover the immune biomarkers underlying hepatitis B e antigen (HBeAg) seroconversion: a need for more translational study.
Topics: Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interleukins; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2012 |
Telbivudine improves the function of myeloid dendritic cells in patients with chronic hepatitis B.
Topics: Adult; Antigens, CD; Antiviral Agents; B7-H1 Antigen; Cells, Cultured; Dendritic Cells; Down-Regulation; Gene Expression; Hepatitis B Antigens; Hepatitis B, Chronic; HLA-DR Antigens; Humans; Interferon-alpha; Interleukin-12; Male; Monocytes; Myeloid Cells; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Up-Regulation; Virus Replication | 2012 |
Interruption of mother-to-infant transmission of hepatitis B: time to include selective antiviral prophylaxis?
Topics: Antiviral Agents; Developing Countries; Female; Hepatitis B; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Vaccination | 2012 |
Effects of telbivudine treatment on the circulating CD4⁺ T-cell subpopulations in chronic hepatitis B patients.
Topics: Adult; Antiviral Agents; Case-Control Studies; CD4-Positive T-Lymphocytes; Cytokines; Female; Hepatitis B, Chronic; Humans; Immune System; Interferon-gamma; Leukocytes, Mononuclear; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Th17 Cells; Thymidine; Time Factors | 2012 |
Current practice of chronic hepatitis B treatment in Southern Italy.
Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Italy; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Patterns, Physicians'; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Young Adult | 2012 |
Telbivudin as prophylaxis for hepatitis B virus recurrence after liver transplantation: a case series in single-center experience.
Topics: Adult; Case-Control Studies; Female; Hepatitis B; Humans; Liver Transplantation; Male; Middle Aged; Nucleosides; Pyrimidinones; Recurrence; Telbivudine; Thymidine; Viral Load | 2012 |