Page last updated: 2024-08-16

tegafur and warfarin

tegafur has been researched along with warfarin in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's2 (9.52)18.2507
2000's5 (23.81)29.6817
2010's11 (52.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Hirose, S; Kito, M; Takeshima, S; Urakami, K; Yoshida, S1
Inoue, H; Ogawa, J; Shohtsu, A1
Inoue, H; Kawada, S; Koide, S; Ogawa, J; Shohtsu, A; Tsurumi, T1
Inoue, H; Kawada, S; Koide, S; Ogawa, J; Shohtsu, A1
Miyazawa, N; Uematsu, T; Wada, K1
Kaniwa, N; Murayama, N; Nakajima, Y; Ohno, Y; Ozawa, S; Sai, K; Sawada , J1
Ariyoshi, N; Daigo, S; Fujieda, M; Ikeda, K; Kamataki, T; Koizumi, W; Nagayama, S; Nishioka, Y; Saigenji, K; Takahashi, Y; Tanabe, S; Yamazaki, H1
Ishii, E; Kondo, M; Munakata, M; Sakata, Y; Shitara, K; Wada, R1
Anami, S; Azuma, J; Fujii, C; Fujino, M; Furukawa, H; Matsumura, T; Nishiguchi, T; Ohno, M; Ohsato, H; Tsuge, M; Yamamoto, A; Yasui, Y1
Kubota, Y; Marutaka, M; Orita, Y; Yoshida, R1
Chatani, T; Doi, Y; Fukuda, H; Horiki, M; Iwasaki, R; Kashihara, T; Kitada, M; Kondo, S; Murayama, Y; Okuno, M; Sano, I1
Egashira, N; Kubota, T; Nonaka, T; Oishi, R; Sonoda, M; Takada, A; Watanabe, H; Yamada, T; Yano, T1
Hori, S; Kondo, G; Maeda, T; Miki, A; Satoh, H; Sawada, Y; Yamamuro, F1
Ito, S; Nakamura, Y; Noumi, T; Sasaki, Y1
Chiba, M; Ishii, Y; Yamada, H; Yamamiya, I; Yoshisue, K1
Itoh, H; Jinbu, Y; Kusama, M; Miyagi, N; Nakai, Y; Noguchi, T; Shinozaki, Y; Sugiyama, T; Tsuchiya, Y; Watanabe, H1
Hirashiki, A; Hirooka, Y; Murohara, T; Yamada, K; Yamamura, K; Yano, K1
Fuse, N; Ikegawa, K; Nomura, H; Saito, S; Suzuki, S; Yamamoto, K1
Doki, Y; Haraguchi, N; Hata, T; Kudo, T; Mizushima, T; Mori, M; Nishimura, J; Sakai, D; Satoh, T; Takahashi, H; Yamamoto, H1
Ikegawa, K; Saito, S; Suzuki, S; Yamamoto, K1

Reviews

1 review(s) available for tegafur and warfarin

ArticleYear
[Reinforcement of warfarin action in a patient administered S-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:1

    Topics: Aged; Anticoagulants; Antimetabolites, Antineoplastic; Cardiomyopathy, Hypertrophic; Cerebral Infarction; Drug Combinations; Drug Interactions; Humans; Male; Mouth Neoplasms; Neoplasms, Squamous Cell; Oxonic Acid; Tachycardia, Ventricular; Tegafur; Warfarin

2015

Other Studies

20 other study(ies) available for tegafur and warfarin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
High-performance liquid chromatography with chemiluminescence detection of serum levels of pre-column derivatized fluoropyrimidine compounds.
    Journal of chromatography, 1990, Aug-24, Volume: 530, Issue:1

    Topics: Chromatography, High Pressure Liquid; Coumarins; Floxuridine; Fluorine; Fluorouracil; Humans; Molecular Structure; Pyrimidines; Tegafur; Umbelliferones; Uridine

1990
[Interactions between UFT and anticoagulants].
    Nihon Geka Gakkai zasshi, 1987, Volume: 88, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Dihydrouracil Dehydrogenase (NAD+); Drug Interactions; Drug Synergism; Humans; Lung Neoplasms; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Tegafur; Uracil; Warfarin

1987
Interactions between UFT and anticoagulants in lung cancer patients.
    The Japanese journal of surgery, 1988, Volume: 18, Issue:3

    Topics: Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Drug Interactions; Drug Therapy, Combination; Humans; Lung Neoplasms; Postoperative Care; Tegafur; Ticlopidine; Uracil; Warfarin

1988
[Experimental and clinical study of interactions between fluorinated pyrimidine derivatives and anticoagulants].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:8

    Topics: Animals; Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Fluorouracil; Humans; Lung Neoplasms; Neoplasm Transplantation; Pyrimidines; Rats; Rats, Inbred Strains; Tegafur; Ticlopidine; Uracil; Warfarin

1988
1-(Tetrahydro-2-furanyl)-5-fluorouracil (Ftorafur) determined in rat hair as an index of drug exposure.
    Journal of pharmaceutical sciences, 1993, Volume: 82, Issue:12

    Topics: Animals; Coumarins; Drug Stability; Fluorescence; Fluorescent Dyes; Hair; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred Strains; Tegafur

1993
Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:5

    Topics: Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Cell Division; Colonic Neoplasms; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Fluorouracil; Gene Expression; Humans; Hydroxylation; Microsomes; Mixed Function Oxygenases; Tegafur; Transfection; Tumor Cells, Cultured

2001
A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur.
    Pharmacogenetics, 2002, Volume: 12, Issue:4

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; DNA Primers; DNA, Neoplasm; Drug Combinations; Escherichia coli; Genotype; Humans; Kinetics; Middle Aged; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxonic Acid; Polymerase Chain Reaction; Polymorphism, Genetic; Pyridines; Recombinant Proteins; Stomach Neoplasms; Tegafur; Transfection

2002
[A case of duodenal carcinoma with massive peritoneal carcinomatosis complicating a pulmonary embolism].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Combinations; Drug Therapy, Combination; Duodenal Neoplasms; Female; Heparin; Humans; Middle Aged; Oxonic Acid; Peritoneal Neoplasms; Pulmonary Embolism; Quality of Life; Taxoids; Tegafur; Warfarin

2006
[A case of bleeding tendency due to warfarin in a patient treated with chemotherapy by S-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:8

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Duodenal Neoplasms; Hemorrhage; Humans; Male; Oxonic Acid; Stereoisomerism; Tegafur; Thrombosis; Treatment Failure; Warfarin

2008
[Difficult management of warfarin anticoagulant therapy due to S-1 administration for gastric cancer--report of a case].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:9

    Topics: Aged; Anticoagulants; Antimetabolites, Antineoplastic; Cerebral Infarction; Chemotherapy, Adjuvant; Drug Combinations; Gastrectomy; Humans; Male; Oxonic Acid; Stomach Neoplasms; Tegafur; Warfarin

2009
[A case of type 4 gastric cancer with peritoneal dissemination complicating venous thromboembolism treated effectively by combination of S-1 and warfarin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Combined Modality Therapy; Drug Combinations; Female; Gastroscopy; Humans; Middle Aged; Neoplasm Staging; Oxonic Acid; Peritoneal Neoplasms; Quality of Life; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed; Venous Thromboembolism; Warfarin

2010
Timing of expression of blood coagulation abnormality in patients treated with warfarin and s-1 concomitantly.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2010, Volume: 130, Issue:7

    Topics: Aged; Aged, 80 and over; Anticoagulants; Blood Coagulation Disorders; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; International Normalized Ratio; Male; Middle Aged; Monitoring, Physiologic; Oxonic Acid; Retrospective Studies; Tegafur; Time Factors; Warfarin

2010
Individual differences in prothrombin time-international normalized ratio variation following coadministration of the anticancer agents S-1 and warfarin: 3 case reports.
    International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:11

    Topics: Aged; Anticoagulants; Antimetabolites, Antineoplastic; Drug Combinations; Drug Interactions; Female; Humans; International Normalized Ratio; Male; Middle Aged; Oxonic Acid; Prothrombin Time; Tegafur; Warfarin

2011
Acute aortic thrombosis during cisplatin based chemotherapy for gastric cancer.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:9

    Topics: Acute Disease; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Aortic Diseases; Aortography; Arterial Occlusive Diseases; Carcinoma, Signet Ring Cell; Cisplatin; Dexamethasone; Drug Combinations; Heparin; Humans; Oxonic Acid; Stomach Neoplasms; Tegafur; Thrombosis; Tomography, X-Ray Computed; Warfarin

2013
Effect of CYP2A6 genetic polymorphism on the metabolic conversion of tegafur to 5-fluorouracil and its enantioselectivity.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:9

    Topics: Cell Line; Coumarins; Cytochrome P-450 CYP2A6; DNA, Complementary; Escherichia coli; Fluorouracil; Humans; Microsomes, Liver; Nicotine; Polymorphism, Genetic; Sf9 Cells; Tegafur

2014
A Successful Case of a Patient Undergoing Warfarin and S-1 Therapy Using Internet-based Control of Home-measured PT-INR.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2015, Volume: 135, Issue:7

    Topics: Cholangiocarcinoma; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; International Normalized Ratio; Internet; Male; Middle Aged; Monitoring, Physiologic; Oxonic Acid; Prothrombin Time; Tegafur; Warfarin

2015
[Evaluation of Drug Interaction between S-1 and Warfarin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:1

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antimetabolites, Antineoplastic; Drug Combinations; Drug Interactions; Female; Humans; Male; Middle Aged; Neoplasms; Oxonic Acid; Prothrombin Time; Retrospective Studies; Tegafur; Warfarin

2016
Impact of capecitabine and S-1 on anticoagulant activity of warfarin in patients with gastrointestinal cancer.
    Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:2

    Topics: Anticoagulants; Antimetabolites, Antineoplastic; Capecitabine; Drug Combinations; Drug Interactions; Female; Gastrointestinal Neoplasms; Humans; International Normalized Ratio; Male; Middle Aged; Oxonic Acid; Prothrombin Time; Retrospective Studies; Tegafur; Warfarin

2016
Evaluation of the anticoagulant effect and timing of the concomitant use of S-1 and warfarin.
    The Journal of international medical research, 2016, Volume: 44, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antimetabolites, Antineoplastic; Drug Combinations; Drug Interactions; Female; Humans; International Normalized Ratio; Male; Middle Aged; Oxonic Acid; Prothrombin Time; Retrospective Studies; Stomach Neoplasms; Tegafur; Warfarin

2016
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