tedizolid-phosphate and vorapaxar

tedizolid-phosphate has been researched along with vorapaxar* in 2 studies

Other Studies

2 other study(ies) available for tedizolid-phosphate and vorapaxar

Article	Year
Biotransformation of fluorophenyl pyridine carboxylic acids by the model fungus Cunninghamella elegans. Xenobiotica; the fate of foreign compounds in biological systems, 2017, Volume: 47, Issue:9 1. Fluorine plays a key role in the design of new drugs and recent FDA approvals included two fluorinated drugs, tedizolid phosphate and vorapaxar, both of which contain the fluorophenyl pyridyl moiety. 2. To investigate the likely phase-I (oxidative) metabolic fate of this group, various fluorinated phenyl pyridine carboxylic acids were incubated with the fungus Cunninghamella elegans, which is an established model of mammalian drug metabolism. 3. Topics: Biotransformation; Carboxylic Acids; Chromatography, High Pressure Liquid; Cunninghamella; Gas Chromatography-Mass Spectrometry; Lactones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver; Organophosphates; Oxazoles; Pyridines	2017
New drugs 2015, part 2. Nursing, 2015, Volume: 45, Issue:7 Topics: Antibodies, Monoclonal, Humanized; Benzhydryl Compounds; Benzofurans; Cyclopropanes; Diphosphates; Drug Approval; Drug Therapy; Glucagon-Like Peptide 1; Glucosides; Glycopeptides; Humans; Lactones; Lipoglycopeptides; Organophosphates; Oxazoles; Pyridines; Sulfates; Teicoplanin; United States; United States Food and Drug Administration	2015

Article

Year

Biotransformation of fluorophenyl pyridine carboxylic acids by the model fungus Cunninghamella elegans.

Xenobiotica; the fate of foreign compounds in biological systems, 2017, Volume: 47, Issue:9

1. Fluorine plays a key role in the design of new drugs and recent FDA approvals included two fluorinated drugs, tedizolid phosphate and vorapaxar, both of which contain the fluorophenyl pyridyl moiety. 2. To investigate the likely phase-I (oxidative) metabolic fate of this group, various fluorinated phenyl pyridine carboxylic acids were incubated with the fungus Cunninghamella elegans, which is an established model of mammalian drug metabolism. 3.

Topics: Biotransformation; Carboxylic Acids; Chromatography, High Pressure Liquid; Cunninghamella; Gas Chromatography-Mass Spectrometry; Lactones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver; Organophosphates; Oxazoles; Pyridines

2017

New drugs 2015, part 2.

Nursing, 2015, Volume: 45, Issue:7

Topics: Antibodies, Monoclonal, Humanized; Benzhydryl Compounds; Benzofurans; Cyclopropanes; Diphosphates; Drug Approval; Drug Therapy; Glucagon-Like Peptide 1; Glucosides; Glycopeptides; Humans; Lactones; Lipoglycopeptides; Organophosphates; Oxazoles; Pyridines; Sulfates; Teicoplanin; United States; United States Food and Drug Administration

2015