tecastemizole has been researched along with promazine in 1 studies
| Studies (tecastemizole) | Trials (tecastemizole) | Recent Studies (post-2010) (tecastemizole) | Studies (promazine) | Trials (promazine) | Recent Studies (post-2010) (promazine) |
|---|---|---|---|---|---|
| 18 | 0 | 3 | 1,178 | 60 | 76 |
| Protein | Taxonomy | tecastemizole (IC50) | promazine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.099 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.013 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 1.089 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.299 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.064 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.337 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.3 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.487 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.505 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.018 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.253 | |
| D | Rattus norvegicus (Norway rat) | 1.04 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 1.04 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 5.172 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.13 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.416 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 2.464 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.013 | |
| Histamine H2 receptor | Homo sapiens (human) | 2.858 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.013 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 1.04 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.023 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.099 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 5.172 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 1.04 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.086 | |
| Histamine H1 receptor | Homo sapiens (human) | 1.2291 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.205 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.347 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.274 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 1.04 | |
| D | Bos taurus (cattle) | 0.13 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.271 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Jonghe, S; Herdewijn, P; Moreels, L; Peigneur, S; Rozenski, J; Tian, J; Tytgat, J; Van den Steen, PE; Vandermosten, L | 1 |
1 other study(ies) available for tecastemizole and promazine
| Article | Year |
|---|---|
Astemizole analogues with reduced hERG inhibition as potent antimalarial compounds.
Topics: Antimalarials; Astemizole; Dose-Response Relationship, Drug; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Transcriptional Regulator ERG | 2017 |