tecastemizole has been researched along with piperidines in 9 studies
| Studies (tecastemizole) | Trials (tecastemizole) | Recent Studies (post-2010) (tecastemizole) | Studies (piperidines) | Trials (piperidines) | Recent Studies (post-2010) (piperidines) |
|---|---|---|---|---|---|
| 18 | 0 | 3 | 40,235 | 5,221 | 14,545 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| del Prado, M; Egan, RW; Hey, JA; Kreutner, W; Sherwood, J | 1 |
| De Mol, NJ; Fischer, MJ; Janssen, LH; Kok-Van Esterik, JA; Paulussen, JJ; Van der Heijden, VS | 1 |
| Gong, Q; January, CT; Vorperian, VR; Zhang, S; Zhou, Z | 1 |
| Bachmann, KA | 1 |
| Brown, AM; Ficker, E; Obejero-Paz, CA; Zhao, S | 1 |
| Paakkari, I | 1 |
| Bolo, NR; Frederick, B; Hashoian, R; Hirashima, F; Hsu, R; Hwang, J; Jones, S; Koch, P; Lyoo, IK; Maier, G; Nassar, L; Renshaw, PF; Schneider, E; Sung, Y; Villafuerte, RA; Wilkinson, S | 1 |
| Hefni, A; Lever, R; Moffatt, JD; Page, CP; Paul, W | 1 |
| Cioc, RC; Maes, BU; Mampuys, P; Orru, RV; Ruijter, E; Vlaar, T | 1 |
1 review(s) available for tecastemizole and piperidines
| Article | Year |
|---|---|
Cardiotoxicity of new antihistamines and cisapride.
Topics: Arrhythmias, Cardiac; Astemizole; Benzimidazoles; Butyrophenones; Cetirizine; Cisapride; Heart Diseases; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Serotonin Receptor Agonists; Terfenadine; Triprolidine | 2002 |
8 other study(ies) available for tecastemizole and piperidines
| Article | Year |
|---|---|
Comparative analysis of the cardiotoxicity proclivities of second generation antihistamines in an experimental model predictive of adverse clinical ECG effects.
Topics: Animals; Arrhythmias, Cardiac; Benzimidazoles; Blood Pressure; Electrocardiography; Guinea Pigs; Heart Diseases; Heart Rate; Hemodynamics; Histamine H1 Antagonists; Male; Models, Biological; Piperidines | 1996 |
Effects of the anti-allergics astemizole and norastemizole on Fc epsilon RI receptor-mediated signal transduction processes.
Topics: Animals; Anti-Allergic Agents; Astemizole; Benzimidazoles; Calcium; Cell Adhesion; Cell Line; Erythrocyte Membrane; Exocytosis; Fibronectins; Hemolysis; Hypotonic Solutions; Inosine Triphosphate; Piperidines; Protein Tyrosine Phosphatases; Rats; Receptors, IgE; Signal Transduction | 1997 |
Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole.
Topics: Astemizole; Benzimidazoles; Cation Transport Proteins; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Histamine H1 Antagonists; Humans; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Terfenadine; Trans-Activators; Transcriptional Regulator ERG | 1999 |
Norastemizole Sepracor.
Topics: Animals; Anti-Allergic Agents; Benzimidazoles; Clinical Trials as Topic; Contraindications; Drugs, Investigational; Humans; Piperidines; Rhinitis, Allergic, Seasonal; Structure-Activity Relationship | 2000 |
The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
Topics: Anti-Arrhythmia Agents; Astemizole; Benzimidazoles; Binding Sites; Blotting, Western; Cation Transport Proteins; Cell Line; Cell Membrane; Cisapride; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gastrointestinal Agents; Histamine H1 Antagonists; Humans; Inhibitory Concentration 50; Ions; Long QT Syndrome; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Piperidines; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Folding; Pyridines; Quaternary Ammonium Compounds; Quinidine; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2002 |
Magnetic resonance spectroscopy for measuring the biodistribution and in situ in vivo pharmacokinetics of fluorinated compounds: validation using an investigation of liver and heart disposition of tecastemizole.
Topics: Adult; Animals; Anti-Allergic Agents; Benzimidazoles; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Echo-Planar Imaging; Female; Fluorine Compounds; Fluorine Radioisotopes; Half-Life; Humans; Liver; Magnetic Resonance Spectroscopy; Male; Middle Aged; Myocardium; Piperidines; Reproducibility of Results; Tissue Distribution | 2006 |
Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Astemizole; Benzimidazoles; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Dermatitis, Atopic; Dexamethasone; Disease Models, Animal; Endothelium, Vascular; Eosinophils; Guinea Pigs; Histamine H1 Antagonists; Humans; Inflammation; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred BALB C; Piperidines; Receptors, Histamine H1; Respiratory Hypersensitivity; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2007 |
Sustainable synthesis of diverse privileged heterocycles by palladium-catalyzed aerobic oxidative isocyanide insertion.
Topics: Astemizole; Benzimidazoles; Catalysis; Cyanides; Diamines; Guanidines; Heterocyclic Compounds; Oxidation-Reduction; Palladium; Piperidines | 2012 |