tecastemizole has been researched along with perhexiline in 5 studies
| Studies (tecastemizole) | Trials (tecastemizole) | Recent Studies (post-2010) (tecastemizole) | Studies (perhexiline) | Trials (perhexiline) | Recent Studies (post-2010) (perhexiline) |
|---|---|---|---|---|---|
| 18 | 0 | 3 | 572 | 92 | 83 |
| Protein | Taxonomy | tecastemizole (IC50) | perhexiline (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 1.4852 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 4.064 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 3.2942 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 3.5919 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 1.0932 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.38 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.9408 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 2.7105 | |
| D | Rattus norvegicus (Norway rat) | 7.7625 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7625 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 3.1186 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7625 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7625 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 3.2942 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 7.7625 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 7.7687 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 2.5992 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Keserü, GM | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Jia, L; Sun, H | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
5 other study(ies) available for tecastemizole and perhexiline
| Article | Year |
|---|---|
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |