td-5108 and norcisapride

td-5108 has been researched along with norcisapride* in 1 studies

Other Studies

1 other study(ies) available for td-5108 and norcisapride

ArticleYear
mu-Opioid/5-HT4 dual pharmacologically active agents-efforts towards an effective opioid analgesic with less GI and respiratory side effects (Part I).
    Bioorganic & medicinal chemistry letters, 2009, Oct-01, Volume: 19, Issue:19

    Novel compounds were prepared that united the pharmacologies of the mu-opioid tramadol with the 5-HT4 agonists metoclopramide and norcisapride. The synthesis, chiral separation and in vitro activity of the new compounds is described.

    Topics: Analgesics, Opioid; Cisapride; Gastrointestinal Transit; Humans; Metoclopramide; Receptors, Opioid, mu; Receptors, Serotonin, 5-HT4; Respiratory System; Serotonin 5-HT4 Receptor Agonists; Stereoisomerism; Tramadol

2009