Compounds > tc 81
Page last updated: 2024-09-03

tc 81 and diltiazem

tc 81 has been researched along with diltiazem in 2 studies

Compound Research Comparison

Studies
(tc 81)		Trials
(tc 81)		Recent Studies (post-2010)
(tc 81)		Studies
(diltiazem)		Trials
(diltiazem)		Recent Studies (post-2010) (diltiazem)
10006,4021,073578

Protein Interaction Comparison

ProteinTaxonomytc 81 (IC50)diltiazem (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.45
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.605
Cytochrome P450 3A4Homo sapiens (human)1.8366
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.896
Voltage-dependent L-type calcium channel subunit alpha-1DRattus norvegicus (Norway rat)0.896
Sodium channel protein type 1 subunit alphaHomo sapiens (human)9
Sodium channel protein type 4 subunit alphaHomo sapiens (human)9
Sodium channel protein type 7 subunit alphaHomo sapiens (human)9
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.605
Voltage-dependent L-type calcium channel subunit alpha-1SRattus norvegicus (Norway rat)0.896
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.605
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.605
Sodium channel protein type 5 subunit alphaHomo sapiens (human)9
Sodium channel protein type 9 subunit alphaHomo sapiens (human)9
Sodium channel protein type 2 subunit alphaHomo sapiens (human)9
Sodium channel protein type 3 subunit alphaHomo sapiens (human)9
Sodium channel protein type 11 subunit alphaHomo sapiens (human)9
Sodium channel protein type 8 subunit alphaHomo sapiens (human)9
Sodium channel protein type 10 subunit alphaHomo sapiens (human)9

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aoki, K; Kishimoto, T; Naruchi, T; Okamiya, Y; Takeshita, T; Tanabe, H1
Aoki, K; Hoshina, K; Kishimoto, T; Okamiya, Y; Sunakawa, K; Takeshita, T1

Other Studies

2 other study(ies) available for tc 81 and diltiazem

ArticleYear
Effect of TC-81, a new dihydropyridine derivative, on K(+)-induced contraction in rat aorta.
    European journal of pharmacology, 1991, Nov-19, Volume: 205, Issue:1

    Topics: Animals; Aorta; Calcium; Calcium Radioisotopes; Dihydropyridines; Diltiazem; In Vitro Techniques; Isometric Contraction; Male; Nicardipine; Nifedipine; Papaverine; Potassium; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilator Agents

1991
[Effect of palonidipine hydrochloride (TC-81), a novel calcium antagonist, on the canine coronary artery].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1993, Volume: 102, Issue:1

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Dihydropyridines; Diltiazem; Dogs; In Vitro Techniques; Male; Nifedipine; Potassium; Vasodilator Agents

1993