Page last updated: 2024-09-03

tazobactam and piperacillin, tazobactam drug combination

tazobactam has been researched along with piperacillin, tazobactam drug combination in 78 studies

Compound Research Comparison

Studies (tazobactam)	Trials (tazobactam)	Recent Studies (post-2010) (tazobactam)	Studies (piperacillin, tazobactam drug combination)	Trials (piperacillin, tazobactam drug combination)	Recent Studies (post-2010) (piperacillin, tazobactam drug combination)
1,327	153	694	1,263	136	914

Research

Studies (78)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (6.41)	18.2507
2000's	7 (8.97)	29.6817
2010's	38 (48.72)	24.3611
2020's	28 (35.90)	2.80

Authors

Authors	Studies
Danziger, LH; Occhipinti, DJ; Rodvold, KA; Schoonover, LL	1
Bansal, S; Doepner, M; Halstenson, CE; Johnson, CA; Keane, WF; Onorato, JJ; Sia, L; Tantillo, K; Wong, MO; Zimmerman, SW	1
Murray, BE; Okhuysen, PC; Singh, KV	1
Haruta, T; Kobayashi, Y; Nishio, T	1
Birawska, I; Fuchs, J; Szulakowska, E	1
Archontaki, HA; Marselos, SC	1
Crisostomo, AC; Erasmo, AA; Hong, YS; Lee, KU; Lo, CM; Yan, LN	1
Burgess, DS; Frei, CR; Hampton, SL	1
Chow, P; Godambe, S; Maulidi, H	1
Arndt, PA; Garratty, G; Leger, RM	1
Aldeyab, MA; Bailie, R; Elshibly, SM; Hanley, J; Hughes, CM; Kearney, MP; McDowell, DA; McElnay, JC; McMahon, MA; Scott, MG	1
Jones, RN; Moet, GJ; Sader, HS; Watters, AA	1
Drusano, GL; Lodise, TP; Patel, N; Scheetz, MH	1
Bauer, SR; Butler, R; Connor, MJ; Fissell, WH; Groszek, J; Hofmann, CL; Rehm, SJ; Salem, C	1
Bulik, CC; Keel, RA; Nicolau, DP; Sutherland, CA; Tessier, PR	1
Beumier, M; Cotton, F; De Backer, D; Hites, M; Jacobs, F; Lorent, S; Roisin, S; Seyler, L; Surin, R; Taccone, FS; Vincent, JL; Wolff, F	1
Argento, AC; Heavner, MS; Ruggero, MA; Topal, JE	1
López-Cerero, L; Muniain, MA; Pascual, Á; Retamar, P; Rodríguez-Baño, J	1
Fortier, LC; Garneau, JR; Valiquette, L	1
Bruchmann, S; Cabot, G; Haussler, S; Juan, C; Moyà, B; Mulet, X; Oliver, A; Zamorano, L	1
Carroll, F; Pai, MP; Truong, J; Zheng, H	1
Chen, R; Qian, CY; Qian, Q; Sun, MR; Wang, LY; Wang, ML; Zou, SL	1
Berrazeg, M; Broutin, I; Fournier, D; Jeannot, K; Loeffert, S; Ntsogo Enguéné, VY; Plésiat, P	1
Fowler, RC; Geyer, CN; Hanson, ND; Hawkey, P; Johnson, JR; Johnston, B; Weissman, SJ	1
Banerjee, R; Boyce, TG; Cunningham, SA; Hasassri, ME; Jeraldo, PR; Kaye, KS; Norgan, AP; Patel, R; Pogue, JM; Weissman, SJ	1
Mikamo, H; Sugimoto, N; Yamagishi, Y	1
Compain, F; Grohs, P; Kaibi, I; Lavollay, M; Mainardi, JL; Morand, P; Podglajen, I; Taieb, G	1
Carlier, M; De Cock, PAJG; de Jaeger, A; De Paepe, P; Delanghe, JR; Della Pasqua, OE; Robays, H; van Dijkman, SC; Vande Walle, J; Verstraete, AG; Willems, J	1
Ahir, H; Foo, J; Merchant, S; Prabhu, V; Sarpong, E	1
Kim, HS; Kim, HY; Kim, YK; Lee, J; Lee, JA; Lee, SS; Seo, YB; Song, W; Uh, Y	1
Anderson, CW; Cazares, KS; Denunzio, TM; Lustik, MB; Patel, SM	1
Goodlet, KJ; Nailor, MD; Nicolau, DP	1
Hindler, JA; Humphries, RM; Miller, SA; Wong-Beringer, A	1
Castanheira, M; Flamm, RK; Pfaller, MA; Shortridge, D	1
Álvarez-Marín, R; Aznar, J; Lepe, JA; Ortiz de la Rosa, JM; Pachón, J; Rodríguez-Villodres, Á; Smani, Y	1
Guerra Valero, YC; Lipman, J; Naicker, S; Ordenez Meija, JL; Parker, SL; Roberts, JA; Wallis, SC	1
Castanheira, M; Duncan, LR; Mendes, RE; Sader, HS; Shortridge, D	1
Colton, B	1
Colby, J; Fissell, WH; Groszek, JJ; Patel, P; Seegmiller, A; Shotwell, M; Verhoven, SM; Verstraete, A	1
Alobaid, A; Hiremath, S; Kanji, S; Patel, R; Porteous, R; Roberts, JA; Watpool, I; Xie, J; Zelenitsky, S; Zhang, G	1
Caccese, E; Marinai, C; Messori, A; Trippoli, S; Tulli, G	1
Farkas, A; Heil, EL; Nicolau, DP; Roberts, JA; Thom, KA	1
Bando, S; Egawa, S; Kasai, K; Kimura, T; Kira, S; Kiyota, H; Koide, H; Murakami, M; Yamada, H	1
Aitken, E; Gould, IM; Hijazi, K; Joshi, C; Oggioni, MR; Zamudio, R	1
Beaulieu, C; Kurczewski, L; Yajnik, V	1
Chen, GJ; Chen, WT; Foo, J; Morel, C; Pan, SC; Wang, JT	1
Albanèse, J; Bornet, C; Curti, C; Fersing, C; Guinard, B; Lamy, E; Mathias, F; Primas, N; Souab, HK; Vanelle, P	1
Cabri, W; Cerisoli, L; Ferrazzano, L; Martelli, G; Ricci, A; Tolomelli, A; Viola, A	1
Brock, B; Friberg, LE; Kristoffersson, AN; Maarbjerg, SF; Nielsen, EI; Schrøder, H; Thorsted, A; Wang, M	1
Hoban, DJ; Lob, SH; Motyl, MR; Sahm, DF; Young, K	1
Autmizguine, J; Kassir, N; Lavigne, J; Litalien, C; Théorêt, Y; Thibault, C	1
Cabot, G; Fernández-Esgueva, M; Fraile-Ribot, PA; Huarte, R; López-Calleja, AI; Mulet, X; Oliver, A; Rezusta, A	1
Carvalhaes, CG; Castanheira, M; Doyle, TB; Sader, HS; Streit, JM	1
Bassetti, M; Giacobbe, DR; Pelosi, P; Robba, C; Vena, A	1
He, A; He, L; Qian, Y	1
Garello, P; Livermore, DM; Mushtaq, S; Vickers, A; Woodford, N	1
Carvalhaes, CG; Castanheira, M; Sader, HS; Shortridge, D	1
Aitken, SL; Heil, EL; Monogue, ML; Pogue, JM	1
Chen, WT; DeRyke, CA; Kazmierczak, KM; Lob, SH; Motyl, MR; Sahm, DF; Siddiqui, F; Young, K	1
Dhamija, P; Goyal, T; Gupta, P; Trikha, V; Vardhan, G	1
Almind, SR; Andreasen, MR; Frimodt-Møller, N; Hansen, KH; Hertz, FB; Jelsbak, L; Nielsen, KL; Schønning, K	1
Kim, HI; Kim, HS; Kim, YK; Lee, DH; Lee, SH; Park, S	1
Akers, KS; Chung, KK; DeLuca, JP; Livezey, JR; Nadeau, RJ; Por, ED; Pruskowski, KA; Selig, DJ	1
Gillani, SW; Hussain, MW; Mahmood, RK; Rathore, HA; Saeed, MW; Vippadapu, P	1
Alosaimy, S; Amaya, L; Biagi, M; Chandler, E; Cubillos, A; Davis, SL; Finch, N; Hobbs, ALV; Holger, D; Jorgensen, SCJ; Kufel, WD; Kunz Coyne, AJ; Lagnf, AM; Li, D; Molina, KC; Moore, WJ; Morrisette, T; Mubarez, M; Patch, M; Polisetty, RS; Rebold, N; Rico, M; Rybak, MJ; Sakoulas, G; Simon, SP; Smith, IMK; Tran, NN; Truong, J; Venugopalan, V; Veve, MP; Witucki, P; Wrin, J; Yost, C	1
Castanheira, M; Chen, WT; Pfaller, M; Shortridge, D; Streit, J; Tulloch, M	1
Ankravs, MJ; Bellomo, R; Deane, AM; Rechnitzer, T; Roberts, JA; Sharrock, L; Wallis, SC	1
Al Jalali, V; Ballarini, N; Bauer, M; Bergmann, F; Jorda, A; König, F; Lackner, E; Nussbaumer-Pröll, A; Oesterreicher, Z; Reiter, B; Stimpfl, T; Wölfl-Duchek, M; Wulkersdorfer, B; Zeitlinger, M	1
Laramie, KE; Miller, MA; Mueller, SW; Roper, SE; Torian, SC; Wiktor, AJ	1
Haines, RR; Hammer, KA; Putsathit, P; Tai, AS	1
Maseda, E; Suárez de la Rica, A	1
Caldwell, JT; Dong, S; Fei, L; Goldstein, SL; Hasson, D; Kaplan, J; Slagle, C; Tang Girdwood, S; Tang, P; Vinks, AA	1
Gill, CM; Nicolau, DP	1
An, G; Balevic, SJ; Chan, AW; Cohen-Wolkowiez, M; Conrad, T; Gu, K; Hemmersbach-Miller, M; Kirkpatrick, CMJ; Landersdorfer, CB; Schmader, KE; Swamy, GK; Walter, EB; Winokur, PL	1
Arends, SJR; Carvalhaes, CG; Castanheira, M; Mendes, RE; Sader, HS; Shortridge, D	1
Bauer, SR; Campbell, MJ; Dettmer, MR; Erickson, RM; Fertel, BS; Sacha, GL; Wesolek, JL	1
Enache Leonte, G; Ghiciuc, CM; Luca, CM; Onofrei, MI; Postolache, P; Rosu, FM; Sapaniuc, C	1
Colman, R; De Cock, PA; De Paepe, P; Devreese, M; Dhont, E; Hermans, E; Vande Walle, J; Verougstraete, N; Zeitlinger, M	1

Reviews

7 review(s) available for tazobactam and piperacillin, tazobactam drug combination

Article	Year
Piperacillin/tazobactam: a new beta-lactam/beta-lactamase inhibitor combination. The Annals of pharmacotherapy, 1995, Volume: 29, Issue:5 Topics: Bacterial Infections; beta-Lactamase Inhibitors; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Infant; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	1995
Molecular Adsorbent Recirculating System (MARS(®)) removal of piperacillin/tazobactam in a patient with acetaminophen-induced acute liver failure. Transplant infectious disease : an official journal of the Transplantation Society, 2013, Volume: 15, Issue:2 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Inactivation, Metabolic; Liver Failure, Acute; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2013
Treatment of extended-spectrum β-lactamases infections: what is the current role of new β-lactams/β-lactamase inhibitors? Current opinion in infectious diseases, 2020, Volume: 33, Issue:6 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Ceftaroline; Ceftazidime; Cephalosporins; Cyclooctanes; Drug Combinations; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Public Health; Sepsis; Tazobactam	2020
Pharmacokinetics of piperacillin and tazobactam in critically Ill patients treated with continuous kidney replacement therapy: A mini-review and population pharmacokinetic analysis. Journal of clinical pharmacy and therapeutics, 2022, Volume: 47, Issue:8 Topics: Anti-Bacterial Agents; Critical Illness; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Replacement Therapy; Tazobactam	2022
A Meta-Analysis on Clinical Outcomes of Ceftolozane versus Piperacillin in Combination with Tazobactam in Patients with Complicated Urinary Tract Infections. BioMed research international, 2022, Volume: 2022 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pyelonephritis; Tazobactam; Urinary Tract Infections	2022
Controversies in the management of ESBL-producing Enterabacterales. Clinical Implications. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2022, Volume: 35 Suppl 3 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cephalosporins; Humans; Meropenem; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Tazobactam	2022
Optimization of Therapy and the Risk of Probiotic Use during Antibiotherapy in Septic Critically Ill Patients: A Narrative Review. Medicina (Kaunas, Lithuania), 2023, Feb-28, Volume: 59, Issue:3 Topics: Adolescent; Anti-Bacterial Agents; Critical Illness; Humans; Piperacillin, Tazobactam Drug Combination; Tazobactam	2023

Trials

3 trial(s) available for tazobactam and piperacillin, tazobactam drug combination

Article	Year
Randomized comparison of piperacillin/tazobactam versus imipenem/cilastatin in the treatment of patients with intra-abdominal infection. Asian journal of surgery, 2004, Volume: 27, Issue:3 Topics: Abdominal Abscess; Adult; Anti-Bacterial Agents; Cilastatin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2004
Randomized controlled trial of piperacillin-tazobactam, cefepime and ertapenem for the treatment of urinary tract infection caused by extended-spectrum beta-lactamase-producing Escherichia coli. BMC infectious diseases, 2017, 06-07, Volume: 17, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Cross Infection; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Genotype; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Republic of Korea; Tazobactam; Urinary Tract Infections	2017
Comparison of pharmacokinetics and stability of generics of cefepime, linezolid and piperacillin/tazobactam with their respective originator drugs: an intravenous bioequivalence study in healthy volunteers. The Journal of antimicrobial chemotherapy, 2022, 10-28, Volume: 77, Issue:11 Topics: Anti-Bacterial Agents; Cefepime; Drugs, Generic; Healthy Volunteers; Humans; Linezolid; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Therapeutic Equivalency	2022

Other Studies

68 other study(ies) available for tazobactam and piperacillin, tazobactam drug combination

Article	Year
Pharmacokinetics of tazobactam M1 metabolite after administration of piperacillin/tazobactam in subjects with renal impairment. Journal of clinical pharmacology, 1994, Volume: 34, Issue:12 Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; Penicillanic Acid; Peritoneal Dialysis, Continuous Ambulatory; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Dialysis; Renal Insufficiency; Tazobactam	1994
Susceptibility of beta-lactamase-producing enterococci to piperacillin with tazobactam. Diagnostic microbiology and infectious disease, 1993, Volume: 17, Issue:3 Topics: beta-Lactamase Inhibitors; Culture Media; Drug Synergism; Drug Therapy, Combination; Enterococcus faecalis; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Piperacillin; Piperacillin, Tazobactam Drug Combination; Streptomycin; Tazobactam	1993
[Transferability of tazobactam/piperacillin (TAZ/PIPC) to cerebrospinal fluid of rabbit with meningitis caused by Staphylococcus aureus]. The Japanese journal of antibiotics, 1998, Volume: 51, Issue:6 Topics: Animals; beta-Lactamase Inhibitors; Drug Therapy, Combination; Enzyme Inhibitors; Meningitis, Bacterial; Penicillanic Acid; Penicillins; Piperacillin; Piperacillin, Tazobactam Drug Combination; Rabbits; Staphylococcal Infections; Tazobactam; Time Factors	1998
[Evaluation of in vitro susceptibility of hospital bacterial isolates to piperacillin and tazocin (piperacillin/tazobactam]. Medycyna doswiadczalna i mikrobiologia, 1998, Volume: 50, Issue:1-2 Topics: beta-Lactamase Inhibitors; Body Fluids; Cross Infection; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Piperacillin, Tazobactam Drug Combination; Species Specificity; Tazobactam	1998
Development and optimization of a reversed-phase high-performance liquid chromatographic method for the determination of piperacillin and tazobactam in tazocin injectable powder. Journal of pharmaceutical and biomedical analysis, 2002, Jul-31, Volume: 29, Issue:5 Topics: Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Particle Size; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Powders; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tazobactam	2002
Influence of culture site-specific MIC distributions on the pharmacokinetic and pharmacodynamic properties of piperacillin/tazobactam and piperacillin: a data analysis. Clinical therapeutics, 2006, Volume: 28, Issue:7 Topics: Anti-Bacterial Agents; Bacterial Infections; Data Interpretation, Statistical; Enzyme Inhibitors; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2006
Suspected drug reaction with piperacillin/tazobactam, in a premature infant. British journal of clinical pharmacology, 2008, Volume: 65, Issue:6 Topics: Anti-Bacterial Agents; Exanthema; Humans; Infant, Newborn; Infant, Premature; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sepsis; Tazobactam	2008
Serological studies of piperacillin antibodies. Transfusion, 2008, Volume: 48, Issue:11 Topics: Adsorption; Anemia, Hemolytic; Antibodies; Antibody Specificity; beta-Lactamase Inhibitors; Blood Donors; Coombs Test; Drug Hypersensitivity; Erythrocyte Membrane; Humans; Penicillanic Acid; Penicillin G; Piperacillin; Piperacillin, Tazobactam Drug Combination; Plasma; Tazobactam	2008
Comparison of the effect of ciprofloxacin and Tazocin on the incidence of meticillin-resistant Staphylococcus aureus (MRSA) in an Intensive Care Unit. International journal of antimicrobial agents, 2008, Volume: 32, Issue:6 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Ciprofloxacin; Cross Infection; Data Interpretation, Statistical; Drug Combinations; Electrophoresis, Gel, Pulsed-Field; Hand Disinfection; Hygiene; Intensive Care Units; Methicillin-Resistant Staphylococcus aureus; Penicillanic Acid; Personnel, Hospital; Piperacillin; Piperacillin, Tazobactam Drug Combination; Staphylococcal Infections; Tazobactam	2008
Expanded studies of piperacillin/tazobactam formulations: variations among branded product lots and assessment of 46 generic lots. Diagnostic microbiology and infectious disease, 2009, Volume: 65, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; Drugs, Generic; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2009
Identification of optimal renal dosage adjustments for traditional and extended-infusion piperacillin-tazobactam dosing regimens in hospitalized patients. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Area Under Curve; Bayes Theorem; Cross Infection; Drug Combinations; Female; Hospitalization; Humans; Infusions, Intravenous; Kidney; Kidney Function Tests; Male; Microbial Sensitivity Tests; Middle Aged; Models, Statistical; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Pneumococcal; Reproducibility of Results; Tazobactam; United States; United States Food and Drug Administration	2010
Therapeutic drug monitoring of piperacillin-tazobactam using spent dialysate effluent in patients receiving continuous venovenous hemodialysis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:2 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Dialysis Solutions; Drug Monitoring; Female; Hemofiltration; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Dialysis; Tazobactam	2011
In vivo comparison of CXA-101 (FR264205) with and without tazobactam versus piperacillin-tazobactam using human simulated exposures against phenotypically diverse gram-negative organisms. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Combinations; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thigh	2012
Case-control study of drug monitoring of β-lactams in obese critically ill patients. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Case-Control Studies; Cefepime; Ceftazidime; Cephalosporins; Drug Monitoring; Enzyme Inhibitors; Female; Humans; Male; Meropenem; Middle Aged; Obesity; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Replacement Therapy; Sepsis; Shock, Septic; Tazobactam; Thienamycins; Young Adult	2013
Impact of the MIC of piperacillin-tazobactam on the outcome of patients with bacteremia due to extended-spectrum-β-lactamase-producing Escherichia coli. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cohort Studies; Drug Therapy, Combination; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Treatment Outcome; Urinary Tract Infections	2013
Prevention of Clostridium difficile spore formation by sub-inhibitory concentrations of tigecycline and piperacillin/tazobactam. BMC infectious diseases, 2014, Jan-15, Volume: 14 Topics: Anti-Bacterial Agents; Ciprofloxacin; Clostridioides difficile; Humans; Metronidazole; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Ribotyping; Spores, Bacterial; Tazobactam; Tigecycline; Vancomycin	2014
Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of AmpC. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Imipenem; Meropenem; Microbial Sensitivity Tests; Mutation; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins	2014
Do formulation differences between the reference listed drug and generic piperacillin-tazobactam impact reconstitution? Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:3 Topics: Administration, Intravenous; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Drugs, Generic; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2015
Population Pharmacokinetics and Pharmacodynamics of Piperacillin/Tazobactam in Patients with Nosocomial Infections. European journal of drug metabolism and pharmacokinetics, 2016, Volume: 41, Issue:4 Topics: Anti-Bacterial Agents; Body Weight; Cross Infection; Female; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2016
Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10 Topics: Adaptation, Physiological; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Gene Expression; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Protein Structure, Secondary; Protein Structure, Tertiary; Pseudomonas aeruginosa; Tazobactam; Ticarcillin	2015
Evaluation of CTX-M steady-state mRNA, mRNA half-life and protein production in various STs of Escherichia coli. The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Disk Diffusion Antimicrobial Tests; Escherichia coli; Genotype; Humans; Immunoblotting; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Tazobactam	2016
An Immunocompromised Child with Bloodstream Infection Caused by Two Escherichia coli Strains, One Harboring NDM-5 and the Other Harboring OXA-48-Like Carbapenemase. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ciprofloxacin; Ertapenem; Escherichia coli; Female; Gentamicins; Humans; Immunocompromised Host; Meropenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Thienamycins; Tobramycin	2016
Proposed breakpoint of piperacillin/tazobactam against extended spectrum β-lactamases producing bacteria in bacteremia. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2017, Volume: 23, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Enterobacteriaceae; Female; Humans; Japan; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Tazobactam	2017
Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:4 Topics: Achromobacter denitrificans; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Stenotrophomonas maltophilia; Tazobactam; Thienamycins	2017
Dose optimization of piperacillin/tazobactam in critically ill children. The Journal of antimicrobial chemotherapy, 2017, 07-01, Volume: 72, Issue:7 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Tazobactam	2017
Cost-effectiveness of ceftolozane/tazobactam plus metronidazole compared with piperacillin/tazobactam as empiric therapy for the treatment of complicated intra-abdominal infections based on the in-vitro surveillance of bacterial isolates in the UK. Journal of medical economics, 2017, Volume: 20, Issue:8 Topics: Anti-Bacterial Agents; Bacteriological Techniques; Cephalosporins; Clinical Protocols; Drug Combinations; Drug Therapy, Combination; Female; Gram-Negative Bacterial Infections; Humans; Intraabdominal Infections; Male; Metronidazole; Models, Econometric; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Quality-Adjusted Life Years; Tazobactam; United Kingdom	2017
Vancomycin vs. Vancomycin/Piperacillin-Tazobactam-Associated Acute Kidney Injury in Noncritically Ill Patients at a Tertiary Care Military Treatment Facility. Military medicine, 2017, Volume: 182, Issue:9 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Hospitals, Military; Humans; Incidence; Logistic Models; Male; Middle Aged; Military Personnel; Odds Ratio; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Tazobactam; Tertiary Care Centers; Vancomycin	2017
Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12 Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Febrile Neutropenia; Humans; Iatrogenic Disease; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Tazobactam; Thienamycins; Tobramycin	2017
Activity of Ceftolozane-Tazobactam and Ceftazidime-Avibactam against Beta-Lactam-Resistant Pseudomonas aeruginosa Isolates. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Gene Expression; Humans; Los Angeles; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins	2017
Antimicrobial Activity of Ceftolozane-Tazobactam Tested Against Enterobacteriaceae and Pseudomonas aeruginosa with Various Resistance Patterns Isolated in U.S. Hospitals (2013-2016) as Part of the Surveillance Program: Program to Assess Ceftolozane-Tazoba Microbial drug resistance (Larchmont, N.Y.), 2018, Volume: 24, Issue:5 Topics: Amikacin; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Hospitals; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins	2018
Heteroresistance to Piperacillin-Tazobactam in Clinical Isolates of Escherichia coli Sequence Type 131. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Multiple, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2018
A UHPLC-MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. Journal of pharmaceutical and biomedical analysis, 2018, Jan-30, Volume: 148 Topics: Calibration; Chromatography, High Pressure Liquid; Critical Illness; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Plasma; Renal Replacement Therapy; Sensitivity and Specificity; Tandem Mass Spectrometry; Tazobactam; Urine	2018
Activity of Ceftolozane-Tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae Isolates Collected from Respiratory Tract Specimens of Hospitalized Patients in the United States during 2013 to 2015. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Gene Expression; Hospitalization; Humans; Isoenzymes; Meropenem; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Plasmids; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory System; Retrospective Studies; Tazobactam; United States	2018
Prolonged Infusions: The Significance of How. Critical care medicine, 2018, Volume: 46, Issue:2 Topics: Anti-Bacterial Agents; Piperacillin, Tazobactam Drug Combination; Tazobactam	2018
Therapeutic drug monitoring of piperacillin and tazobactam by RP-HPLC of residual blood specimens. Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 482 Topics: Blood Specimen Collection; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Monitoring; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sepsis; Tazobactam	2018
Piperacillin Population Pharmacokinetics in Critically Ill Adults During Sustained Low-Efficiency Dialysis. The Annals of pharmacotherapy, 2018, Volume: 52, Issue:10 Topics: Adult; Aged; Anti-Bacterial Agents; Critical Illness; Female; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Renal Dialysis; Renal Replacement Therapy; Tazobactam	2018
Piperacillin-Tazobactam: Extended Infusion Versus Continuous Infusion. Critical care medicine, 2018, Volume: 46, Issue:7 Topics: Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2018
Pharmacodynamic Target Attainment for Cefepime, Meropenem, and Piperacillin-Tazobactam Using a Pharmacokinetic/Pharmacodynamic-Based Dosing Calculator in Critically Ill Patients. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9 Topics: Anti-Bacterial Agents; Cefepime; Critical Illness; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Tazobactam	2018
Antimicrobial prophylaxis for transurethral resection of bladder tumor: A retrospective comparison of preoperative single-dose administration of piperacillin and tazobactam/piperacillin. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2018, Volume: 24, Issue:12 Topics: Administration, Intravenous; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteriuria; Female; Fever; Humans; Male; Piperacillin; Piperacillin, Tazobactam Drug Combination; Preoperative Period; Retrospective Studies; Tazobactam; Urinary Bladder Neoplasms	2018
Phylogenetic analysis of resistance to ceftazidime/avibactam, ceftolozane/tazobactam and carbapenems in piperacillin/tazobactam-resistant Pseudomonas aeruginosa from cystic fibrosis patients. International journal of antimicrobial agents, 2019, Volume: 53, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Combinations; Drug Resistance, Bacterial; Female; Hospitals; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Piperacillin, Tazobactam Drug Combination; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Scotland; Tazobactam; Whole Genome Sequencing	2019
Cefepime challenge after piperacillin/tazobactam-induced thrombocytopenia. Journal of thrombosis and thrombolysis, 2019, Volume: 48, Issue:1 Topics: Adult; Anti-Bacterial Agents; Cefepime; Female; Humans; Immunity, Humoral; Male; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Aspiration; Tazobactam; Thrombocytopenia	2019
Comparing ceftolozane/tazobactam versus piperacillin/tazobactam as empiric therapy for complicated urinary tract infection in Taiwan: A cost-utility model focusing on gram-negative bacteria. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2019, Volume: 52, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Cost-Benefit Analysis; Gram-Negative Bacteria; Humans; Middle Aged; Piperacillin, Tazobactam Drug Combination; Quality-Adjusted Life Years; Taiwan; Tazobactam; Time Factors; Treatment Outcome; Urinary Tract Infections; Young Adult	2019
Stability Studies of Antipyocyanic Beta-Lactam Antibiotics Used in Continuous Infusion. Die Pharmazie, 2019, 06-01, Volume: 74, Issue:6 Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Imipenem; Meropenem; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2019
Novel insights into the chemistry of an old medicine: A general degradative pathway for penicillins from a piperacillin/tazobactam stability study. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Aug-01, Volume: 136 Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2019
Population pharmacokinetics of piperacillin in febrile children receiving cancer chemotherapy: the impact of body weight and target on an optimal dosing regimen. The Journal of antimicrobial chemotherapy, 2019, 10-01, Volume: 74, Issue:10 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Body Weight; Child; Child, Preschool; Female; Fever; Glomerular Filtration Rate; Humans; Infant; Male; Microbial Sensitivity Tests; Neoplasms; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2019
Activity of ceftolozane-tazobactam and comparators against Pseudomonas aeruginosa from patients in different risk strata - SMART United States 2016-2017. Journal of global antimicrobial resistance, 2020, Volume: 20 Topics: Abdomen; Adult; Aged; Ceftazidime; Cephalosporins; Female; Humans; Levofloxacin; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Respiratory System; Tazobactam; United States; Urinary Tract	2020
Population Pharmacokinetics and Safety of Piperacillin-Tazobactam Extended Infusions in Infants and Children. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:11 Topics: Anti-Bacterial Agents; Child; Child, Preschool; Cross Infection; Female; Humans; Infant; Male; Microbial Sensitivity Tests; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2019
Characterization of AmpC β-lactamase mutations of extensively drug-resistant Pseudomonas aeruginosa isolates that develop resistance to ceftolozane/tazobactam during therapy. Enfermedades infecciosas y microbiologia clinica (English ed.), 2020, Volume: 38, Issue:10 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Microbial Sensitivity Tests; Multilocus Sequence Typing; Mutation; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2020
Antimicrobial Activity of Ceftazidime-Avibactam, Ceftolozane-Tazobactam and Comparators Tested Against Microbial drug resistance (Larchmont, N.Y.), 2021, Volume: 27, Issue:3 Topics: Amikacin; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactam Resistance; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Phenotype; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Tazobactam; United States; Whole Genome Sequencing	2021
Imipenem-resistant Pseudomonas aeruginosa treated with piperacillin/tazobactam in a patient with severe pneumonia: a case report and related literature review. Annals of palliative medicine, 2021, Volume: 10, Issue:1 Topics: Aged; Female; Humans; Imipenem; Microbial Sensitivity Tests; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Pseudomonas aeruginosa; Tazobactam	2021
Cefepime/tazobactam compared with other tazobactam combinations against problem Gram-negative bacteria. International journal of antimicrobial agents, 2021, Volume: 57, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Tazobactam	2021
Comparative activity of newer β-lactam/β-lactamase inhibitor combinations against Pseudomonas aeruginosa from patients hospitalized with pneumonia in European medical centers in 2020. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022, Volume: 41, Issue:2 Topics: Azabicyclo Compounds; beta-Lactamase Inhibitors; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Hospitalization; Humans; Imipenem; Jupiter; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2022
The role of tazobactam-based combinations for the management of infections due to extended-spectrum β-lactamase-producing Enterobacterales: Insights from the Society of Infectious Diseases Pharmacists. Pharmacotherapy, 2021, Volume: 41, Issue:10 Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Drug Combinations; Enterobacteriaceae Infections; Humans; Pharmacists; Piperacillin, Tazobactam Drug Combination; Societies, Medical; Tazobactam; United States	2021
In vitro activity of ceftolozane/tazobactam against Gram-negative isolates collected from ICU patients with lower respiratory tract infections in seven Asian countries-SMART 2017-2019. Journal of global antimicrobial resistance, 2022, Volume: 29 Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Intensive Care Units; Meropenem; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tazobactam; Thailand	2022
In vitro study of elution kinetics and biological activity of piperacillin/tazobactam and gentamicin in acrylic bone cement. Orthopaedics & traumatology, surgery & research : OTSR, 2022, Volume: 108, Issue:8 Topics: Anti-Bacterial Agents; Bone Cements; Gentamicins; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymethyl Methacrylate; Tazobactam	2022
Efficacy of piperacillin-tazobactam and cefotaxime against Escherichia coli hyperproducing TEM-1 in a mouse peritonitis infection model. International journal of antimicrobial agents, 2022, Volume: 59, Issue:4 Topics: Animals; Anti-Bacterial Agents; Antigens, CD; beta-Lactamases; Cefotaxime; Escherichia coli; Escherichia coli Infections; Mice; Microbial Sensitivity Tests; Neoplasm Proteins; Peritonitis; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2022
Population pharmacokinetics of piperacillin/tazobactam in critically ill Korean patients and the effects of extracorporeal membrane oxygenation. The Journal of antimicrobial chemotherapy, 2022, 04-27, Volume: 77, Issue:5 Topics: Adult; Anti-Bacterial Agents; Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Republic of Korea; Tazobactam	2022
Nephrotoxicity of Vancomycin in Combination With Beta-Lactam Agents: Ceftolozane-Tazobactam vs Piperacillin-Tazobactam. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 02-08, Volume: 76, Issue:3 Topics: Acute Kidney Injury; Anti-Bacterial Agents; beta-Lactams; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Tazobactam; Vancomycin	2023
Activity of Ceftolozane-Tazobactam Against Gram-Negative Isolates from Australia and New Zealand as part of the PACTS Surveillance 2016-2018. Journal of global antimicrobial resistance, 2022, Volume: 31 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Meropenem; Microbial Sensitivity Tests; New Zealand; Penicillanic Acid; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Tazobactam	2022
Clearance of Piperacillin-Tazobactam and Vancomycin During Continuous Renal Replacement With Regional Citrate Anticoagulation. Therapeutic drug monitoring, 2023, 04-01, Volume: 45, Issue:2 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Anticoagulants; Citrates; Citric Acid; Critical Illness; Humans; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Vancomycin	2023
Burn Injury and Augmented Renal Clearance: A Case for Optimized Piperacillin-Tazobactam Dosing. Journal of burn care & research : official publication of the American Burn Association, 2023, 01-05, Volume: 44, Issue:1 Topics: Anti-Bacterial Agents; Burns; Critical Illness; Humans; Microbial Sensitivity Tests; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2023
Activity of newest generation β-lactam/β-lactamase inhibitor combination therapies against multidrug resistant Pseudomonas aeruginosa. Scientific reports, 2022, 10-07, Volume: 12, Issue:1 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; Carbapenems; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Lactams; Microbial Sensitivity Tests; Monobactams; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2022
Relationship between piperacillin concentrations, clinical factors and piperacillin/tazobactam-associated acute kidney injury. The Journal of antimicrobial chemotherapy, 2023, 02-01, Volume: 78, Issue:2 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Child; Drug Therapy, Combination; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Tazobactam; Vancomycin; Young Adult	2023
Piperacillin/Tazobactam Dose Optimization in the Setting of Piperacillin/Tazobactam-susceptible, Carbapenem-resistant Pseudomonas aeruginosa: Time to Reconsider Susceptible Dose Dependent. Clinical therapeutics, 2023, Volume: 45, Issue:1 Topics: Anti-Bacterial Agents; Carbapenems; Humans; Infusions, Intravenous; Microbial Sensitivity Tests; Mitomycin; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Tazobactam	2023
Population Pharmacokinetics of Piperacillin/Tazobactam Across the Adult Lifespan. Clinical pharmacokinetics, 2023, Volume: 62, Issue:1 Topics: Aged; Anti-Bacterial Agents; Canada; Creatinine; Frailty; Humans; Longevity; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam	2023
Comparative activity of newer β-lactam/β-lactamase inhibitor combinations against Pseudomonas aeruginosa isolates from US medical centres (2020-2021). International journal of antimicrobial agents, 2023, Volume: 61, Issue:4 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; Ceftazidime; Cephalosporins; Drug Combinations; Hospitals; Humans; Imipenem; Lactams; Meropenem; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2023
Association between emergency department sepsis order set design and delay to second dose piperacillin-tazobactam administration. The American journal of emergency medicine, 2023, Volume: 67 Topics: Adult; Anti-Bacterial Agents; Emergency Service, Hospital; Humans; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Sepsis; Tazobactam	2023
Microdialysis as a safe and feasible method to study target-site piperacillin-tazobactam disposition in septic piglets and children. International journal of antimicrobial agents, 2023, Volume: 62, Issue:5 Topics: Animals; Anti-Bacterial Agents; Child; Humans; Microdialysis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sepsis; Swine; Tazobactam	2023