Page last updated: 2024-09-03

tazobactam and linezolid

tazobactam has been researched along with linezolid in 10 studies

Compound Research Comparison

Studies
(tazobactam)
Trials
(tazobactam)
Recent Studies (post-2010)
(tazobactam)
Studies
(linezolid)
Trials
(linezolid)
Recent Studies (post-2010) (linezolid)
1,3271536943,9162222,188

Protein Interaction Comparison

ProteinTaxonomytazobactam (IC50)linezolid (IC50)
Prostaglandin G/H synthase 1Homo sapiens (human)8.19
Amine oxidase [flavin-containing] BHomo sapiens (human)2.1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialHomo sapiens (human)8.19

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S1
Hidai, H1
Adams, CA; Cioffi, WG; Connolly, MD; Gregg, S; Heffernan, DS; Monaghan, SF; Stephen, A; Thakkar, RK1
Bandettini, R; Barco, S; Cangemi, G; Castagnola, E; Maffia, A; Tripodi, G1
Frey, L; Maier, B; Suhr, A; Teupser, D; Vogeser, M; Zander, J; Zoller, M1
Ballard, A; Biddy, BA; Bouley, R; Burnham, CA; Chang, M; Dantas, G; Gonzales, PR; Mobashery, S; Pesesky, MW; Schroeder, VA; Suckow, MA; Wolter, WR1
Ourique, C; Rego-Costa, F; Torres-Ramalho, P1
Babiak, P; Cizmarova, I; Kovac, A; Mikus, P; Parrak, V; Piestansky, J; Secnik, P1
Al Jalali, V; Ballarini, N; Bauer, M; Bergmann, F; Jorda, A; König, F; Lackner, E; Nussbaumer-Pröll, A; Oesterreicher, Z; Reiter, B; Stimpfl, T; Wölfl-Duchek, M; Wulkersdorfer, B; Zeitlinger, M1
Balasubramanium, G; Elangovan, R; Gupta, SS; Lodha, T; Muthulakshmi, T; Perumal, V; Sivaraman, GK; Visnuvinayagam, S; Yadav, A1

Reviews

1 review(s) available for tazobactam and linezolid

ArticleYear
[Antibiotics--TAZ/PIPC, synercid, linezolid, everninomicin].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:4

    Topics: Acetamides; Adult; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Drug Combinations; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Linezolid; Oxazolidinones; Penicillanic Acid; Penicillins; Piperacillin; Protein Synthesis Inhibitors; Tazobactam; Virginiamycin

2001

Trials

1 trial(s) available for tazobactam and linezolid

ArticleYear
Comparison of pharmacokinetics and stability of generics of cefepime, linezolid and piperacillin/tazobactam with their respective originator drugs: an intravenous bioequivalence study in healthy volunteers.
    The Journal of antimicrobial chemotherapy, 2022, 10-28, Volume: 77, Issue:11

    Topics: Anti-Bacterial Agents; Cefepime; Drugs, Generic; Healthy Volunteers; Humans; Linezolid; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam; Therapeutic Equivalency

2022

Other Studies

8 other study(ies) available for tazobactam and linezolid

ArticleYear
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen

2007
Empiric antibiotics pending bronchoalveolar lavage data in patients without pneumonia significantly alters the flora, but not the resistance profile, if a subsequent pneumonia develops.
    The Journal of surgical research, 2013, Volume: 181, Issue:2

    Topics: Acetamides; Anti-Bacterial Agents; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Penicillanic Acid; Piperacillin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tazobactam; Treatment Outcome; Vancomycin; Wounds and Injuries

2013
Quantification of piperacillin, tazobactam, meropenem, ceftazidime, and linezolid in human plasma by liquid chromatography/tandem mass spectrometry.
    Journal of chemotherapy (Florence, Italy), 2015, Volume: 27, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Ceftazidime; Child; Chromatography, Liquid; Drug Monitoring; Humans; Limit of Detection; Linezolid; Meropenem; Penicillanic Acid; Piperacillin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tazobactam; Thienamycins

2015
Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation.
    Clinical chemistry and laboratory medicine, 2015, Volume: 53, Issue:5

    Topics: Analytic Sample Preparation Methods; Anti-Bacterial Agents; Automation; Blood Chemical Analysis; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Isotopes; Linezolid; Meropenem; Penicillanic Acid; Piperacillin; Tandem Mass Spectrometry; Tazobactam; Thienamycins; Time Factors

2015
Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA.
    Nature chemical biology, 2015, Volume: 11, Issue:11

    Topics: Allosteric Regulation; Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Drug Synergism; Drug Therapy, Combination; Female; Gene Expression; Humans; Linezolid; Meropenem; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Operon; Penicillanic Acid; Penicillin-Binding Proteins; Piperacillin; Staphylococcal Infections; Tazobactam; Thienamycins

2015
Unusual course of a haematoma of the thigh.
    BMJ case reports, 2017, May-22, Volume: 2017

    Topics: Anti-Bacterial Agents; Delayed Diagnosis; Drainage; Female; Hematoma; Humans; Linezolid; Magnetic Resonance Imaging; Middle Aged; Muscle, Skeletal; Osteomyelitis; Penicillanic Acid; Piperacillin; Soft Tissue Infections; Tazobactam; Thigh

2017
An Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Determination of 4 β-Lactam Antibiotics, Tazobactam, and Linezolid in Human Plasma Samples.
    Therapeutic drug monitoring, 2022, 12-01, Volume: 44, Issue:6

    Topics: Anti-Bacterial Agents; Cefepime; Cefotaxime; Chromatography, High Pressure Liquid; Critical Illness; Drug Monitoring; Humans; Linezolid; Meropenem; Monobactams; Piperacillin; Reproducibility of Results; Tandem Mass Spectrometry; Tazobactam

2022
Prevalence of S. aureus and/or MRSA from seafood products from Indian seafood products.
    BMC microbiology, 2022, 10-01, Volume: 22, Issue:1

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cefoxitin; Gentamicins; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Multilocus Sequence Typing; Ofloxacin; Piperacillin; Prevalence; Rifampin; Seafood; Serine; Staphylococcal Infections; Staphylococcus aureus; Sulbactam; Tazobactam; Trimethoprim, Sulfamethoxazole Drug Combination; Virulence Factors

2022