Compounds > tazobactam
Page last updated: 2024-09-03

tazobactam and cilastatin

tazobactam has been researched along with cilastatin in 14 studies

Compound Research Comparison

Studies
(tazobactam)		Trials
(tazobactam)		Recent Studies (post-2010)
(tazobactam)		Studies
(cilastatin)		Trials
(cilastatin)		Recent Studies (post-2010) (cilastatin)
1,327153694999270137

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (42.86)18.2507
2000's5 (35.71)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Bäckstrand, B; Bergman, L; Brismar, B; Kihlström, E; Malmborg, AS; Mentzing, LO; Nyström, PO; Skau, T; Tunevall, G; Wretlind, B1
Alhava, E; Haapiainen, R; Havia, T; Kivilaakso, E; Laitinen, S; Matikainen, M; Miettinen, P; Niinikoski, J; Pääkkönen, M1
Eklund, AE; Nord, CE1
Adhikari, M; Pillay, DG; Pillay, T; Sturm, AW1
Ambrosetti, P; Aymon, D; Bille, J; Chiolero, R; Cometta, A; Glauser, MP; Harbarth, S; Huber, O; Jaccard, C; Lew, D; Praz, G; Ricou, B; Romand, J; Schneider, R; Troillet, N; Zanetti, G1
Bryce, EA; Frighetto, LO; Jewesson, PJ; Marra, CA; Marra, FO; Reynolds, RP; Sleigh, KM; Stiver, HG1
Naber, KG; Salmen, HC; Savov, O1
Crisostomo, AC; Erasmo, AA; Hong, YS; Lee, KU; Lo, CM; Yan, LN1
Bermúdez, A; Besalduch, J; Nocea, G; Pascual, MJ; Rovira, M; Sanz, MA; Sanz-Rodríguez, C1
Cooper, A; Joshi, M; Kassira, W; McCarthy, M; Metzler, M; Olvey, S1
Leitner, E; Lode, H; Schmitt, DV; Welte, T1
Chin, K; Haruna, A; Ichiyama, S; Ito, I; Kadowaki, S; Kase, M; Matsumoto, H; Mishima, M; Nakai, A; Niimi, A; Tanabe, N; Tsukino, M; Yasutomo, Y1
Albanèse, J; Bornet, C; Curti, C; Fersing, C; Guinard, B; Lamy, E; Mathias, F; Primas, N; Souab, HK; Vanelle, P1
Boucher, HW; Brown, ML; Butterton, JR; Chen, LF; David-Wang, A; Du, J; Kartsonis, NA; Kaye, KS; Losada, MC; Paschke, A; Patel, M; Rizk, ML; Rodríguez Gonzalez, D; Roquilly, A; Tipping, R; Titov, I; Wunderink, RG; Young, K1

Trials

12 trial(s) available for tazobactam and cilastatin

ArticleYear
Piperacillin-tazobactam versus imipenem-cilastatin for treatment of intra-abdominal infections.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:12

    Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Tazobactam; Treatment Outcome

1992
Piperacillin/tazobactam versus imipenem/cilastatin in the treatment of intra-abdominal infections.
    Surgery, gynecology & obstetrics, 1993, Volume: 176, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; beta-Lactamase Inhibitors; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Penicillanic Acid; Peritoneal Diseases; Piperacillin; Tazobactam; Treatment Outcome

1993
A randomized multicenter trial of piperacillin/tazobactam versus imipenem/cilastatin in the treatment of severe intra-abdominal infections. Swedish Study Group.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 31 Suppl A

    Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; beta-Lactamase Inhibitors; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged; Penicillanic Acid; Piperacillin; Tazobactam

1993
Prospective randomized comparison of imipenem-cilastatin and piperacillin-tazobactam in nosocomial pneumonia or peritonitis.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:11

    Topics: Acute Disease; Adult; Aged; Cilastatin; Cilastatin, Imipenem Drug Combination; Cross Infection; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Penicillanic Acid; Peritonitis; Piperacillin; Pneumonia; Prospective Studies; Pseudomonas Infections; Tazobactam

1998
Cost-minimization analysis of piperacillin/tazobactam versus imipenem/cilastatin for the treatment of serious infections: a Canadian hospital perspective.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:2

    Topics: Adult; Anti-Infective Agents; Bacterial Infections; British Columbia; Cilastatin; Costs and Cost Analysis; Decision Trees; Double-Blind Method; Drug Therapy, Combination; Economics, Pharmaceutical; Enzyme Inhibitors; Female; Humans; Imipenem; Male; Models, Economic; Penicillanic Acid; Penicillins; Piperacillin; Prospective Studies; Protease Inhibitors; Statistics, Nonparametric; Tazobactam; Thienamycins; Treatment Outcome

1999
Piperacillin 2 g/tazobactam 0.5 g is as effective as imipenem 0.5 g/cilastatin 0.5 g for the treatment of acute uncomplicated pyelonephritis and complicated urinary tract infections.
    International journal of antimicrobial agents, 2002, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Cilastatin; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Middle Aged; Penicillanic Acid; Penicillins; Piperacillin; Pyelonephritis; Sample Size; Tazobactam; Thienamycins; Urinary Tract Infections

2002
Randomized comparison of piperacillin/tazobactam versus imipenem/cilastatin in the treatment of patients with intra-abdominal infection.
    Asian journal of surgery, 2004, Volume: 27, Issue:3

    Topics: Abdominal Abscess; Adult; Anti-Bacterial Agents; Cilastatin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam

2004
Imipenem/cilastatin versus piperacillin/tazobactam plus amikacin for empirical therapy in febrile neutropenic patients: results of the COSTINE study.
    Current medical research and opinion, 2005, Volume: 21, Issue:5

    Topics: Adult; Amikacin; Anti-Bacterial Agents; Cilastatin; Cost-Benefit Analysis; Drug Therapy, Combination; Enzyme Inhibitors; Female; Fever; Hematopoietic Stem Cell Transplantation; Humans; Imipenem; Male; Middle Aged; Neoplasms; Neutropenia; Penicillanic Acid; Piperacillin; Prospective Studies; Protease Inhibitors; Spain; Tazobactam; Treatment Outcome

2005
Comparison of piperacillin/tazobactam and imipenem/cilastatin, both in combination with tobramycin, administered every 6 h for treatment of nosocomial pneumonia.
    Respiratory medicine, 2006, Volume: 100, Issue:9

    Topics: Anti-Bacterial Agents; Cilastatin; Cross Infection; Double-Blind Method; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Imipenem; Male; Middle Aged; Penicillanic Acid; Piperacillin; Pneumonia, Ventilator-Associated; Protease Inhibitors; Tazobactam; Tobramycin; Treatment Outcome

2006
Piperacillin/tazobactam vs imipenem/cilastatin in the treatment of nosocomial pneumonia--a double blind prospective multicentre study.
    Infection, 2006, Volume: 34, Issue:3

    Topics: Adult; Cilastatin; Cross Infection; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Penicillanic Acid; Piperacillin; Pneumonia; Prospective Studies; Pseudomonas Infections; Tazobactam; Treatment Outcome

2006
Tazobactam/piperacillin for moderate-to-severe pneumonia in patients with risk for aspiration: comparison with imipenem/cilastatin.
    Pulmonary pharmacology & therapeutics, 2010, Volume: 23, Issue:5

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Cilastatin; Community-Acquired Infections; Drug Combinations; Female; Humans; Imipenem; Injections, Intravenous; Male; Nursing Homes; Penicillanic Acid; Piperacillin; Pneumonia, Aspiration; Prospective Studies; Protease Inhibitors; Tazobactam; Treatment Outcome

2010
A Randomized, Double-blind, Multicenter Trial Comparing Efficacy and Safety of Imipenem/Cilastatin/Relebactam Versus Piperacillin/Tazobactam in Adults With Hospital-acquired or Ventilator-associated Bacterial Pneumonia (RESTORE-IMI 2 Study).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 12-06, Volume: 73, Issue:11

    Topics: Adult; Aged; Anti-Bacterial Agents; Azabicyclo Compounds; Cilastatin; Hospitals; Humans; Imipenem; Piperacillin; Tazobactam; Ventilators, Mechanical

2021

Other Studies

2 other study(ies) available for tazobactam and cilastatin

ArticleYear
Piperacillin/tazobactam in the treatment of Klebsiella pneumoniae infections in neonates.
    American journal of perinatology, 1998, Volume: 15, Issue:1

    Topics: Anti-Infective Agents; beta-Lactamase Inhibitors; Cilastatin; Ciprofloxacin; Cross Infection; Drug Combinations; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Inhibitors; Female; Humans; Imipenem; Infant, Newborn; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Protease Inhibitors; Retrospective Studies; Tazobactam; Thienamycins

1998
Stability Studies of Antipyocyanic Beta-Lactam Antibiotics Used in Continuous Infusion.
    Die Pharmazie, 2019, 06-01, Volume: 74, Issue:6

    Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Ceftazidime; Cilastatin; Cilastatin, Imipenem Drug Combination; Imipenem; Meropenem; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tazobactam

2019