taxifolin has been researched along with quercetin in 427 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (2.11) | 18.7374 |
| 1990's | 29 (6.79) | 18.2507 |
| 2000's | 84 (19.67) | 29.6817 |
| 2010's | 211 (49.41) | 24.3611 |
| 2020's | 94 (22.01) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CJ; Geahlen, RL | 1 |
| Augereau, JM; Billon, M; Gleye, J; Herbert, JM; Lale, A; Leconte, M | 1 |
| Habtemariam, S | 1 |
| Jacobson, KA; Moro, S; Sanders, LH; van Rhee, AM | 1 |
| Karioti, A; Konstantinopoulou, M; Skaltsa, H; Skaltsas, S | 1 |
| Fischer, L; Franke, L; George, S; Hoernig, C; Müller-Kuhrt, L; Schneider, G; Schneider, P; Schwarz, O; Steinhilber, D; Tanrikulu, Y; Werz, O | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Gestwicki, JE; Reinke, AA; Seh, HY | 1 |
| Tanaka, R; Tokuda, H; Wada, S; Yasui, Y | 1 |
| Carver, JA; Duggan, PJ; Ecroyd, H; Liu, Y; Meyer, AG; Tranberg, CE | 1 |
| Amić, D; Lucić, B | 1 |
| Alcaro, S; Bolasco, A; Chimenti, F; Chimenti, P; Cirilli, R; Ferretti, R; Fioravanti, R; Orallo, F; Ortuso, F; Rossi, F; Sanna, ML; Secci, D; Yáñez, M | 1 |
| Matsuda, H; Nakamura, S; Nakashima, S; Oda, Y; Xu, F; Yoshikawa, M | 1 |
| Banerji, A; Bose, C; Pandurangan, N | 1 |
| Cai, S; Chu, L; Gao, F; Ji, B; Jia, G; Liu, J; Liu, Y; Wang, A; Wei, Y; Wu, W; Xie, L; Zhang, D; Zhou, F | 1 |
| Huang, J; Jiang, H; Li, H; Li, X; Liao, S; Liu, X; Lu, W; Shan, L; Shen, X; Wang, L; Zhang, S; Zhang, W | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Gažák, R; Křen, V; Kuzma, M; Papoušková, B; Ulrichová, J; Vacek, J; Vrba, J; Weiszenstein, M | 1 |
| Chin, YW; Han, SY; Kong, JY | 1 |
| Ahn, JH; Cho, SH; Hwang, BY; Kim, ES; Kim, S; Lee, C; Lee, MK | 1 |
| Akagi, K; Irie, K; Katayama, S; Masuda, Y; Murakami, K; Nakagawa, Y; Sato, M; Takegoshi, K; Uno, M | 1 |
| Fernandes, E; Freitas, M; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM | 1 |
| Cabrita, EJ; Fernandes, E; Freitas, M; Marques, MM; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM | 1 |
| Dong, MS; Hong, CY; Kim, IS; Kim, SA; Na, CS; Park, MH; Yoo, HH | 1 |
| Balemba, OB; Frank, O; Hofmann, T; Salger, M; Stark, TD; Wakamatsu, J | 1 |
| Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM | 1 |
| Cahlikova, L; Chlebek, J; Havrankova, J; Hofman, J; Hostalkova, A; Lundova, T; Musilek, K; Novotna, E; Wsol, V; Zemanova, L | 1 |
| Akagi, K; Hanaki, M; Irie, K; Murakami, K | 1 |
| Alcaro, S; Ambrosio, FA; Artese, A; Bagetta, D; Catalano, R; Costa, G; Lupia, A; Maruca, A; Mesiti, F; Moraca, F; Ortuso, F; Rocca, R; Romeo, I | 1 |
| Fernandes, E; Fernandes, PA; Freitas, M; Oliveira, A; Proença, C; Ramos, MJ; Ribeiro, D; Silva, AMS; Sousa, JLC | 1 |
| Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V | 1 |
| Gawas, UB; Majik, MS; Mandrekar, VK | 1 |
| Halbach, G; Trost, W | 1 |
| Tang, X; Yuan, C; Zhang, Z; Zhou, M | 1 |
| Geodakyan, SV; Glyzin, VI; Kolesnik, JA; Litvinenko, VI; Tjukavkina, NA; Voskoboinikova, IV | 1 |
| Drzewiecki, G; Kandaswami, C; Middleton, E; Perkins, E; Soloniuk, DS | 2 |
| 'T Hart, BA; Ip Via Ching, TR; Labadie, RP; Van Dijk, H | 1 |
| Drzewiecki, G; Fujitani, T; Middleton, E; Ogasawara, H | 1 |
| Drzewiecki, G; Fujiki, H; Middleton, E; Savliwala, M | 1 |
| Bertrand, C; Landry, Y; Tschirhart, E | 1 |
| Martínez, F | 1 |
| Biziagos, E; Crance, JM; Deloince, R; Passagot, J | 1 |
| Hussain, RA; Kinghorn, AD; Nanayakkara, NP; Pezzuto, JM; Soejarto, DD | 1 |
| Brown, S; Griffiths, LA | 1 |
| Agullo, G; Demigné, C; Favier, ML; Manach, C; Morand, C; Régérat, F; Rémésy, C; Texier, O | 1 |
| Bors, W; Michel, C; Schikora, S | 1 |
| Kolesnik, IuA; Ostroukhova, LA; Radaeva, IA; Rulenko, IA; Shul'kina, SP; Tiukavkina, NA | 1 |
| Kawakishi, S; Nakayama, T; Osawa, T; Yamada, M | 1 |
| Chou, WH; Haraguchi, H; Masuda, H; Mizutani, K; Mochida, Y; Sakai, S; Tamura, Y; Tanaka, O | 1 |
| Igarashi, K; Masuda, H; Mizutani, K; Murakami, N; Uchida, Y | 1 |
| Kolesnik, IuA; Rulenko, IA; Tiukavkina, NA | 2 |
| Chou, WH; Fukuda, A; Haraguchi, H; Mizutani, K; Ohmi, I; Tamura, Y; Tanaka, O | 1 |
| Agullo, G; Chap, H; Gamet-Payrastre, L; Manenti, S; Payrastre, B; Rémésy, C; Viala, C | 1 |
| Price, KR; Rhodes, MJ; Uda, Y; Williamson, G | 1 |
| Kostyuk, VA; Potapovich, AI | 1 |
| Bast, A; Boven, E; Grimbergen, JA; Kramer, K; Kuiper, K; van Acker, SA; van den Berg, DJ; van der Vijgh, WJ | 1 |
| Babenkova, IV; Kapitanov, AB; Klebanov, GI; Lewin, G; Lyubitsky, OB; Nesterova, OA; Popov, IN; Vasil'eva, OV; Zhambalova, BA | 1 |
| Arakawa, T; Furuno, K; Ohnishi, M; Sugihara, N | 1 |
| Barron, D; Comte, G; Conseil, G; Di Pietro, A; El Kirat, K; Maitrejean, M | 1 |
| Dragsted, LO; Jørgensen, LV; Madsen, HL; Skibsted, LH; Thomsen, MK | 1 |
| Calixto, JB; Cechinel-Filho, V; Vaz, ZR; Yunes, RA; Zunino, L | 1 |
| Babenkova, IV; Baginskaya, AI; Eichholz, AA; Kolesnik, YA; Kolhir, VK; Selivanova, IA; Teselkin, YO; Tjukavkina, NA | 1 |
| Klebanov, GI; Lyubitsky, OB; Vasiljeva, OV; Vladimirov, YA | 1 |
| Adeli, K; Chen, B; Franke, AA; Theriault, A; Van Iderstine, SC; Wang, Q | 1 |
| Afanas'ev, IB; Korkina, LG; Kostyuk, VA; Potapovich, AI; Vladykovskaya, EN | 1 |
| Blaut, M; Braune, A; Engst, W; Gütschow, M | 1 |
| Awad, HM; Boersma, MG; Rietjens, IM; Van Bladeren, PJ; van Iersel, ML; Vervoort, J | 1 |
| Awad, HM; Boeren, S; Boersma, MG; Rietjens, IM; van Bladeren, PJ; Vervoort, J | 1 |
| Cao, Y; Cao, Z; Wu, Y; Yang, D; Yi, Y; Zhao, S | 1 |
| Bito, T; Gotoh, A; Ichihashi, M; Packer, L; Roy, S; Sen, CK; Shirakawa, T; Ueda, M | 1 |
| Dapkevicius, A; de Groot, A; Lelyveld, GP; Linssen, JP; van Beek, TA; van Veldhuizen, A; Venskutonis, R | 1 |
| Britsch, L; Lukacin, R; Matern, U; Moriguchi, T; Schiltz, E; Wellmann, F | 1 |
| Aliev, OI; Maslov, MJ; Plotnikov, MB; Tjukavkina, NA; Vasiliev, AS | 2 |
| Bais, HP; Kennan, AJ; Stermitz, FR; Vivanco, JM; Walker, TS | 1 |
| Li, R; Wang, Y; Zhou, L | 1 |
| Cho, J; Dok-Go, H; Jin, C; Kim, HJ; Lee, EH; Lee, J; Lee, KH; Lee, YH; Lee, YS; Song, YS | 1 |
| Caroço, G; Justino, G; Mira, L; Rocha, R; Santos, MR; Silva, MM | 1 |
| Carrier, DJ; Clausen, E; Wallace, SN | 1 |
| Li, C; Lian, Z; Zhang, C; Zhou, Y | 1 |
| Bukharina, IY; Logvinov, SV; Maslov, MY; Petrova, MS; Plotnikov, MB; Tikhonovskaya, OA | 1 |
| BOOTH, AN; DEEDS, F | 1 |
| Budagova, KR; Goncharova, AY; Grigor'ev, AN; Kabakov, AE; Zhmaeva, SV | 1 |
| Kiehlmann, E; Slade, PW | 1 |
| Ueda, H; Yamazaki, C; Yamazaki, M | 1 |
| Carrier, DJ; Clausen, EC; Duan, L | 1 |
| Chen, CF; Chou, YC; Hou, YC; Liao, JF; Liou, KT; Shen, YC; Tien, JH; Wang, WY; Wang, YH | 1 |
| Afanas'ev, IB; Kostyuk, TV; Kostyuk, VA; Potapovich, AI; Strigunova, EN | 1 |
| Alisievich, SV; Fedosova, NF; Kubatiev, AA; Lyadov, KV; Romanova, EP; Rudko, IA | 1 |
| Casaschi, A; Maiyoh, GK; Rubio, BK; Theriault, AG | 1 |
| Kravchenko, LV; Morozov, SV; Tutel'yan, VA | 1 |
| Curti, C; Dorta, DJ; Helena, AF; Mingatto, FE; Pigoso, AA; Prado, IM; Rodrigues, T; Santos, AC; Uyemura, SA | 1 |
| Aliev, OI; Alifirova, VM; Maslov, MIu; Plotnikov, DM; Plotnikov, MB; Tiukavkina, NA; Vasil'ev, AS | 1 |
| Alves, C; Boal, I; Borges, F; Lima, JL; Marques, MP; Reis, S; Siquet, C; Teixeira, S | 1 |
| Chang, CC; Chang, S; Chen, CF; Chou, YC; Hou, YC; Liao, JF; Liou, KT; Shen, YC; Sung, YJ; Wang, WY; Wang, YH | 1 |
| Gakhramanov, FS | 1 |
| Kon', IIa; Kubardiev, MM; Nakusov, TT; Samoĭlik, NI; Shortanova, TKh | 1 |
| Bukharina, IIu; Logvinov, SV; Okorokov, AO; Petrov, IA; Plotnikov, MB; Tikhonovskaia, OA | 1 |
| Ahn, JH; Hur, HG; Kim, BG; Lee, Y; Lim, Y | 1 |
| Dai, SJ; Yu, DQ | 1 |
| Lo Piero, AR; Petrone, G; Puglisi, I | 1 |
| Logvinov, SV; Mikhulya, EP; Plotnikov, MB; Potapov, AV; Varakuta, EY; Zhdankina, AA | 2 |
| Psotová, J; Svobodová, A; Walterová, D | 1 |
| Aoyama, H; Ferreira, CV; Granjeiro, JM; Miranda, MA; Okamoto, AK; Silva, TL | 1 |
| Reddy, AM; Reddy, AR; Reddy, VS; Scheffler, BE; Wienand, U | 1 |
| Chen, J; Lu, C; Lu, Y; Wu, W; Zhang, W | 1 |
| Mu, LH; Zhang, DM | 1 |
| Miyazawa, M; Tamura, N | 1 |
| Cha, KH; Lee, SB; Nho, CW; Selenge, D; Solongo, A | 1 |
| Navarro, JL; Sendra, JM; Sentandreu, E | 1 |
| Dzhafarov, AI; Gakhramanov, FS; Kerimov, KT | 1 |
| Jin, S; Matsuda, M; Osaki, M; Otsuka, Y; Wasaki, J; Watanabe, J; Watanabe, T | 1 |
| Croft, KD; Hodgson, JM; Kroon, PA; Loke, WM; McKinley, AJ; Needs, PW; Proudfoot, JM; Stewart, S | 1 |
| Almar, M; Crespo, I; García-Mediavilla, MV; González, P; González-Gallego, J; Sánchez-Campos, S; Tuñón, MJ | 1 |
| An, SM; Boo, YC; Kim, HJ; Kim, JE | 1 |
| Egorochkin, MA; Kim, YA; Selezneva, II; Tarahovsky, YS; Vasilieva, NA | 1 |
| Choi, SE; Kim, YJ; Lee, CS; Lee, MW | 1 |
| Durnev, AD; Kulakova, AV; Nasonova, VV; Zhanataev, AK | 1 |
| Feng, D; Ma, H; Wang, H; Wang, J; Wu, C; Xie, H | 1 |
| Karlina, MV; Kosman, VM; Makarov, VG; Makarova, MN; Pozharitskaya, ON; Shikov, AN | 1 |
| Jeong, KW; Kang, DI; Kim, Y; Lee, JU; Lee, JY; Shin, SY | 1 |
| Andrews, PK; Davies, NM; Ohgami, Y; Remsberg, CM; Takemoto, JK; Vega-Villa, KR; Yáñez, JA | 2 |
| Chung, KT; Makena, PS; Pierce, SC; Sinclair, SE | 1 |
| Demin, EM; Izmailov, DY; Kagan, VE; Lubitskiy, OB; Matveeva, NS; Novikov, AA; Osipov, AN; Proskurnina, EV; Tikhonov, VP; Vladimirov, YA | 1 |
| Heinämäki, J; Hiltunen, R; Hirsjärvi, S; Makarov, VG; Miroshnyk, I; Mirza, S; Pozharitskaya, ON; Shikov, AN; Urakova, IN; Yliruusi, J | 1 |
| Deng, G; Shen, Q; Wang, X; Xia, H; Xing, F; Zeng, S | 1 |
| Gao, LB; Liu, T; Meng, MX; Wang, XD; Xu, Q; Zeng, S | 1 |
| Hasanloo, T; Kazemi Tabar, SK; Khalili, M; Rahnama, H | 1 |
| Chen, Y; Deuster, P | 1 |
| Elgin, G; Ince, I; Karabay-Yavasoglu, NU; Yesil-Celiktas, O | 1 |
| Abad-García, B; Berrueta, LA; Gallo, B; Garmón-Lobato, S; Vicente, F | 1 |
| Naumov, AA; Potselueva, MM; Shatalin, YV; Sukhomlin, TK | 1 |
| Florêncio, MH; Justino, GC; Mira, L; Rodrigues, M | 1 |
| Barceló, J; Poschenrieder, C; Tolrà, R | 1 |
| Chernyak, YI; Shchukina, OG | 1 |
| Hu, J; Xie, ZT | 1 |
| Ahn, JY; Choi, SE; Choi, YW; Jeong, MS; Joo, SS; Lee, CS; Lee, MK; Lee, MW; Li, K; Moon, NJ; Park, KH; Seo, SJ | 1 |
| Dolezal, M; Megusar, K; Tůma, J; Tůmová, L | 1 |
| Gekkiev, BI; Gorlov, VV; Grigor'ev, AM; Kolyvanov, GB; Litvin, AA; Sariev, AK; Viglinskaia, AO; Zherdev, VP | 1 |
| Naumov, AA; Potselueva, MM | 1 |
| Chu, Z; Kang, T; Zhai, Y; Zhang, H; Zhao, M | 1 |
| Wu, D; Yu, X; Zhang, Y; Zhao, L | 1 |
| Butylkina, AI; Drozd, NN; Kuznetsova, SA; Levdanskiĭ, AV; Makarov, VA; Miftakhova, NT; Vasil'eva, NIu | 1 |
| Högger, P; Kurlbaum, M | 1 |
| Lan, HQ | 1 |
| Canali, R; Frontela, C; Martínez, C; Ros, G; Sánchez-Siles, LM; Virgili, F | 1 |
| Wei-Chao, W; Yan-Jun, Z; Zheng-Yan, L | 1 |
| Koroteev, AM; Koroteev, MP; Kukhareva, TS; Matiushin, AI; Nifant'ev, EE; Rogovskiĭ, VS; Semeĭkin, AV; Shimanovskiĭ, NL | 1 |
| Naumov, AA; Potselueva, MM; Shatalin, YV | 1 |
| Choi, SE; Han, BH; Jeong, MS; Joo, SS; Lee, DI; Lee, MW; Park, KH; Seo, SJ | 1 |
| Chen, XL; Mei, ZN; Shen, YX; Teng, HL; Yang, GZ | 1 |
| Chen, F; Fu, C; Hua, X; Li, H; Lv, X; Qiu, J; Zhao, D; Zhao, Q | 1 |
| Chen, X; Peng, M; Shi, S; Zhang, Y | 1 |
| Freischmidt, A; Heilmann, J; Jürgenliemk, G; Kelber, O; Kraus, B; Müller, J; Okpanyi, SN; Weiser, D | 1 |
| Blaut, M; Braune, A; Cavlar, T; Elsinghorst, PW; Gütschow, M; Müller, A | 1 |
| Kravtsov, AA; Ordzhonikidze, ZG; Paniushkin, VV; Rozhkova, EA; Seĭfulla, RD; Tipikin, IS | 1 |
| Peng, M; Shi, S; Zhang, Y | 1 |
| Cheung, HY; Zeng, LB; Zhang, QF | 1 |
| Guo, YX; Wang, WJ; Zhang, QF; Zheng, G | 1 |
| Kren, V; Papouskova, B; Ulrichova, J; Vacek, J; Vrba, J | 1 |
| Kolosova, NG; Muraleva, NA; Ofitserov, EN; Tikhonov, VP | 1 |
| Rong, Y; Wang, Z; Wu, J; Zhao, B | 1 |
| Weidmann, AE | 1 |
| Mishra, A; Singh, A; Verma, S | 2 |
| Shatalin, IuV; Shubina, VS | 1 |
| Kosina, P; Křen, V; Papoušková, B; Ulrichová, J; Vacek, J; Vrba, J | 1 |
| Diwakar, G; Rana, J; Scholten, JD | 1 |
| Aliev, OI; Ermolaeva, LA; Fomina, TI; Ivanov, IS; Plotnikov, MB; Sidekhmenova, AV; Tyukavkin, NA | 1 |
| Bode, AM; Chen, H; Dong, Z; Lubet, RA; Oi, N; Ok Kim, M | 1 |
| Ma, C; Wang, W; Yang, F; Yang, L; Zhao, C; Zu, Y | 1 |
| Huang, J; Ma, C; Wang, W; Yang, L; Zhao, C; Zu, S; Zu, Y | 1 |
| Frampton, CM; Frevel, MA; Gilchrist, NL; Grigsby, WJ; Pipingas, A | 1 |
| Su, BH; Zhai, YJ; Zhang, YY; Zhou, XY | 1 |
| Wang, X; Zeng, S; Zhou, H | 1 |
| Chen, KL; Cheng, HB; Liu, XQ | 1 |
| Arutyunyan, TV; Korystov, YN; Korystova, AF; Kublik, LN; Levitman, MKh; Shaposhnikova, VV | 2 |
| Areche, C; Cassels, BK; Flórez, E; Osorio, E; Pérez, EG; Ruiz, LM; Tiznado, W | 1 |
| Shatalin, YV; Shubina, VS | 1 |
| Blaskovic, D; Drzik, F; Horakova, L; Veverka, M; Viskupicova, J; Zizkova, P | 1 |
| Kim, YA; Kuznetsova, SM; Muzafarov, EN; Tarahovsky, YS; Yagolnik, EA | 1 |
| Al Zaharna, M; Cheung, HY; Chiu, SK; Wong, MM; Zhang, ZR | 1 |
| Duan, TT; Feng, L; He, B; Jia, XB; Tang, D; Wang, RS; Xu, YH; Zheng, ZG; Zhu, JX; Zhu, Q | 1 |
| Efferth, T; Fu, Y; Gao, C; Liang, L; Luo, M; Wang, W; Zhao, C; Zu, Y | 1 |
| Flegal, JM; Mote, PL; Spindler, SR; Teter, B | 1 |
| Arinç, E; Çelik, H; Koşar, M | 1 |
| Akagi, K; Ikubo, H; Irie, K; Katayama, S; Murakami, K; Nakagawa, Y; Sato, M; Uno, M | 1 |
| Ivanov, IS; Nosarev, AV; Plotnikov, MB; Sidekhmenova, AV; Tyukavkina, NA | 1 |
| Li, B; Tan, YN; Tong, MM; Wang, M; Zhai, YJ | 1 |
| Konstantinova, ML; Leonova, BV; Matiushin, AI; Razumovskiĭ, SD; Rogovskiĭ, VS; Rozenfel'd, MA; Shimanovskiĭ, NL | 1 |
| Imm, JY; Kim, JH; Park, Y; Suh, HJ; Yu, KW | 1 |
| Inai, M; Masuda, A; Masuda, T; Miura, Y | 1 |
| Fu, CY; Li, P; Wang, SB; Xu, JK; Zhang, WK | 1 |
| Hamada, H; Hamada, M; Ishihara, K; Kubota, N; Shimoda, K; Sugamoto, M | 1 |
| Conghua, W; Feng, X; Fuliang, C; Honghui, Y; Hua, C; Linling, L; Shuiyuan, C | 1 |
| Bonello, P; Sherwood, P | 1 |
| Gozulov, AS; Kuznetsov, IuM; Paniushkin, VV; Rozhkova, EA; Seĭfulla, RD; Turova, EA | 1 |
| Křen, V; Papoušková, B; Ulrichová, J; Vacek, J; Vrba, J; Zatloukalová, M | 1 |
| Arriero, Mdel M; Monjo, M; Ramis, JM; Satué, M | 1 |
| Mowat, CG; Pantouris, G | 1 |
| Chen, RC; Ma, XJ; Sun, GB; Sun, X; Sun, XB; Wang, M; Yang, LJ; Yang, ZH | 1 |
| Béliveau, R; Desrosiers, RR; Lamy, S; Ouanouki, A | 1 |
| Tan, YN; Tong, MM; Xu, YY; Zhai, YJ; Zhang, YY | 1 |
| Benet, M; García-Mediavilla, MV; González-Gallego, J; Jorquera, F; Jover, R; Majano, PL; Pisonero-Vaquero, S; Sánchez-Campos, S | 1 |
| Gómez-Florit, M; Monjo, M; Ramis, JM | 1 |
| Baranov, IA; Erlykina, EI; Koryagin, AS; Mochalova, AE; Murach, EI; Smirnova, LA | 1 |
| Li, Y; Wang, W; Wu, W; Zhang, Y; Zhao, X; Zhong, C; Zu, Y | 1 |
| Loers, G; Nifantiev, NE; Schachner, M; Yashunsky, DV | 1 |
| Chu, ZY; Kang, XY; Tong, MM; Zhai, YJ; Zhang, YY | 1 |
| Tong, MM; Wang, TM; Zhai, YJ; Zhang, H; Zhang, YY | 1 |
| Abou-Zaid, MM; Arnason, JT; Cáceres, LA; Liu, R; Liu, S; Saleem, A; Scott, IM; Walshe-Roussel, B; Wang, Z; Waye, A; Wei, Q; Zhao, Z | 1 |
| Chen, F; Jia, J; Liu, Z; Yang, F; Yang, L; Zu, Y | 1 |
| Appazov, NO; Arutyunyan, TV; Ibadullayeva, SZh; Korystov, YN; Korystova, AF; Kublik, LN; Levitman, MKh; Narmanova, RA; Shaposhnikova, VV | 1 |
| Li, Y; Wu, W; Zhang, Y; Zhao, X; Zhong, C; Zu, Y | 1 |
| Li, J; Li, W; Ma, C; Yang, L; Yue, J; Zu, Y | 1 |
| Ha, S; Kim, JH; Kim, JK; Kim, JY; Lee, OS; Oh, CH; Park, G | 1 |
| Lee, CS; Lee, DH; Nam, YJ; Shin, YK; Sohn, DS | 1 |
| Awaad, AS; Awad, E; Esteban, MA | 1 |
| Assof, M; Escribano-Bailón, MT; Fanzone, M; González-Manzano, S; Jofré, V; Pérez-Alonso, J; Santos-Buelga, C | 1 |
| Behr, B; Chromik, AM; Daigeler, A; Goertz, O; Harati, K; Hirsch, T; Kapalschinski, N; Klein-Hitpass, L; Kolbenschlag, J; Lehnhardt, M; Slodnik, P; Uhl, W | 1 |
| Borovskaya, TG; Fomina, TI; Goldberg, VE; Grigor'eva, VA; Kamalova, SI; Krivova, NA; Plotnikov, MB; Poluektova, ME; Shchemerova, YA; Vychuzhanina, AV; Zaeva, OB | 1 |
| Baba, N; Baba, S; Hagiwara, K; Kato, Y; Kawabata, K; Natsume, M; Ohigashi, H; Sakano, T; Tamura, A | 1 |
| Chertkov, VA; Khlupova, ME; Kisin, AV; Morozova, OV; Shestakova, AK; Shumakovich, GP; Vasil'eva, IS; Yaropolov, AI | 1 |
| Alwasel, SH; Gocer, H; Gülçin, İ; Küçük, M; Supuran, CT; Teke, D; Topal, F; Topal, M | 1 |
| Chen, J; Fujino, M; Hei, M; Kimura, S; Li, XK; Takahara, T; Tomita, A; Toyama, S; Yang, Z; Zhao, L; Zhao, M; Zhong, L; Zhu, P; Zhuang, J | 1 |
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14 review(s) available for taxifolin and quercetin
| Article | Year |
|---|---|
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases | 1992 |
The Mediterranean Diet as source of bioactive compounds with multi-targeting anti-cancer profile.
Topics: Anticarcinogenic Agents; Antioxidants; Diet, Mediterranean; Fruit; Humans; Neoplasms; Olive Oil; Vegetables; Wine | 2019 |
Next generation quorum sensing inhibitors: Accounts on structure activity relationship studies and biological activities.
Topics: 4-Butyrolactone; Anti-Bacterial Agents; Biofilms; Cobalt; Coordination Complexes; Drug Design; Furans; Quorum Sensing; Staphylococcus aureus; Structure-Activity Relationship | 2020 |
[Natural flavonoids as dietary antioxidants and biologically active additives].
Topics: Antioxidants; Diet; Flavonoids; Flavonols; Food Additives; Humans; Molecular Structure; Plants, Edible; Quercetin | 1996 |
Dihydroquercetin: More than just an impurity?
Topics: Animals; Antioxidants; Cardiovascular Diseases; Cell Line, Tumor; Humans; Liver Diseases; Neoplasms; Quercetin | 2012 |
"Non-Taxifolin" Derived Flavonolignans: Phytochemistry and Biology.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Flavonolignans; Humans; Phytochemicals; Plant Extracts; Quercetin; Silybum marianum; Staphylococcus aureus | 2015 |
Myeloid heme oxygenase-1: a new therapeutic target in anti-inflammation.
Topics: Aminolevulinic Acid; Animals; Cytoprotection; Enzyme Induction; Heme Oxygenase-1; Humans; Inflammation; Myeloid Cells; Quercetin | 2018 |
Novel Therapeutic Potentials of Taxifolin for Amyloid-β-associated Neurodegenerative Diseases and Other Diseases: Recent Advances and Future Perspectives.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Amyloid Angiopathy; Humans; Neuroprotective Agents; Quercetin | 2019 |
An insight into the health-promoting effects of taxifolin (dihydroquercetin).
Topics: Animals; Health; Humans; Quercetin | 2019 |
Potential Therapeutic Approaches for Cerebral Amyloid Angiopathy and Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Biomarkers; Brain; Cerebral Amyloid Angiopathy; Cilostazol; Disease Models, Animal; Humans; Membrane Glycoproteins; Mice; Neuroprotective Agents; Oxidative Stress; Protein Aggregation, Pathological; Quercetin; Receptors, Immunologic | 2020 |
Advances in biochemistry and the biotechnological production of taxifolin and its derivatives.
Topics: Antioxidants; Flavonoids; Quercetin; Silybum marianum | 2022 |
Pharmacological basis and new insights of taxifolin: A comprehensive review.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Humans; Neoplasms; Quercetin; Randomized Controlled Trials as Topic | 2021 |
New Perspectives of Taxifolin in Neurodegenerative Diseases.
Topics: Alzheimer Disease; Cerebral Amyloid Angiopathy; Humans; Neurodegenerative Diseases; Quercetin | 2023 |
Research Progress of Dihydroquercetin in the Treatment of Skin Diseases.
Topics: Humans; Quality of Life; Quercetin; Skin; Skin Diseases | 2023 |
2 trial(s) available for taxifolin and quercetin
| Article | Year |
|---|---|
Production, composition and toxicology studies of Enzogenol® Pinus radiata bark extract.
Topics: Aged; Animals; Dietary Supplements; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flavonoids; Humans; Hydroxybenzoates; Kidney; Liver; Male; Middle Aged; Mutagens; No-Observed-Adverse-Effect Level; Organ Size; Pinus; Plant Bark; Plant Extracts; Proanthocyanidins; Quercetin; Rats; Rats, Sprague-Dawley; Toxicity Tests | 2012 |
Distribution of Constituents and Metabolites of Maritime Pine Bark Extract (Pycnogenol
Topics: Aged; Blood Cells; Body Mass Index; Body Weight; Catechin; Chromatography, Liquid; Female; Flavonoids; Humans; Male; Middle Aged; Osteoarthritis; Pinus; Plant Bark; Plant Extracts; Polyphenols; Quercetin; Synovial Fluid; Tandem Mass Spectrometry | 2017 |
411 other study(ies) available for taxifolin and quercetin
| Article | Year |
|---|---|
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
Topics: Amino Acid Sequence; Blood Coagulation; Cell Adhesion; Endotoxins; Flavonoids; Humans; In Vitro Techniques; Interleukin-1; Molecular Sequence Data; Monocytes | 1996 |
Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-alpha in L-929 tumor cells.
Topics: Animals; Apoptosis; Drug Synergism; Flavonoids; Mice; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Flavonoid derivatives as adenosine receptor antagonists: a comparison of the hypothetical receptor binding site based on a comparative molecular field analysis model.
Topics: Binding Sites; Computer Simulation; Flavonoids; Kinetics; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Regression Analysis; Reproducibility of Results; Static Electricity; Structure-Activity Relationship | 1998 |
Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity.
Topics: Asteraceae; Gram-Negative Bacteria; Gram-Positive Bacteria; Greece; Helicobacter pylori; Lactones; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Sesquiterpenes; Stereoisomerism | 2003 |
Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening.
Topics: Adult; Arachidonate 5-Lipoxygenase; Biological Products; Cell-Free System; Databases, Factual; Humans; In Vitro Techniques; Lipoxygenase Inhibitors; Models, Molecular; Neutrophils; Pyridines; Structure-Activity Relationship; Tetrahydronaphthalenes; Thiazoles; Thiophenes | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
Topics: Amyloid beta-Peptides; Benzothiazoles; Coloring Agents; Congo Red; Fluorescent Dyes; Indoles; Spectrometry, Fluorescence; Thiazoles | 2009 |
Anti-tumor-initiating effects of phenolic compounds isolated from the bark of Picea jezoensis var. jezoensis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzoates; Imidazoles; Mice; Mutagenicity Tests; Phenols; Picea; Plant Bark; Plant Extracts | 2009 |
Carboxymethylated-kappa-casein: a convenient tool for the identification of polyphenolic inhibitors of amyloid fibril formation.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Caseins; Flavonoids; Humans; Methylation; Milk; Structure-Activity Relationship | 2010 |
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics | 2010 |
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.
Topics: Flavanones; Flavones; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Sulfhydryl Compounds | 2010 |
Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.
Topics: Agaricales; Animals; Antineoplastic Agents; Brassicaceae; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Intramolecular Oxidoreductases; Melanoma, Experimental; Membrane Glycoproteins; Mice; Monophenol Monooxygenase; Oxidoreductases; Plant Extracts; RNA, Messenger; Structure-Activity Relationship; Tumor Cells, Cultured | 2010 |
Synthesis and antioxygenic activities of seabuckthorn flavone-3-ols and analogs.
Topics: Antioxidants; Chemistry Techniques, Synthetic; Flavones; Molecular Structure; Oxygen; Stereoisomerism; Structure-Activity Relationship | 2011 |
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro.
Topics: Antioxidants; Cell Line; Fatty Liver; Flavonoids; Humans; In Vitro Techniques; Oleic Acid; Reactive Oxygen Species; Triglycerides | 2011 |
Natural products as a gold mine for selective matrix metalloproteinases inhibitors.
Topics: Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Biological Products; Cell Line, Tumor; Cell Movement; Computer Simulation; Coumaric Acids; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Molecular Sequence Data; Protease Inhibitors; Protein Structure, Tertiary; Sequence Alignment; Solvents | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
A novel semisynthetic flavonoid 7-O-galloyltaxifolin upregulates heme oxygenase-1 in RAW264.7 cells via MAPK/Nrf2 pathway.
Topics: Acetylcysteine; Animals; Cell Line; Cell Survival; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; MAP Kinase Signaling System; Mice; NF-E2-Related Factor 2; Phosphorylation; Quercetin; Up-Regulation | 2013 |
Flavonoids as receptor tyrosine kinase FLT3 inhibitors.
Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Flavonoids; fms-Like Tyrosine Kinase 3; Humans; Luteolin; Protein Kinase Inhibitors | 2013 |
Chemical constituents from Nelumbo nucifera leaves and their anti-obesity effects.
Topics: Anti-Obesity Agents; Nelumbo; Obesity; Plant Extracts; Plant Leaves | 2013 |
Site-specific inhibitory mechanism for amyloid β42 aggregation by catechol-type flavonoids targeting the Lys residues.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Catechols; Humans; Lysine; Norleucine; Peptide Fragments; Quercetin | 2013 |
Modulation of human neutrophils' oxidative burst by flavonoids.
Topics: Flavonoids; Humans; Luminescent Measurements; Molecular Structure; Neutrophils; Oxidation-Reduction | 2013 |
Inhibition of LOX by flavonoids: a structure-activity relationship study.
Topics: Dose-Response Relationship, Drug; Flavonoids; Glycine max; Humans; Leukotriene B4; Lipoxygenase; Molecular Structure; Neutrophils; Structure-Activity Relationship | 2014 |
Inhibitory effect of Rhus verniciflua Stokes extract on human aromatase activity; butin is its major bioactive component.
Topics: Aromatase; Aromatase Inhibitors; Benzopyrans; Dose-Response Relationship, Drug; Humans; Medicine, Traditional; Molecular Structure; Plant Extracts; Plant Structures; Rhus; Structure-Activity Relationship | 2014 |
Antioxidative compounds from Garcinia buchananii stem bark.
Topics: Antioxidants; Biflavonoids; Depsides; Flavanones; Garcinia; Hydrogen Peroxide; Lactones; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Tanzania; Terpenes; Xanthones | 2015 |
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship | 2015 |
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Apigenin; Daunorubicin; Enzyme Inhibitors; Flavones; Flavonoids; HCT116 Cells; Humans; Luteolin; Molecular Conformation; Molecular Structure; Neoplasms | 2015 |
Structural insights into mechanisms for inhibiting amyloid β42 aggregation by non-catechol-type flavonoids.
Topics: Amyloid beta-Peptides; Dose-Response Relationship, Drug; Flavonoids; Molecular Structure; Peptide Fragments; Structure-Activity Relationship | 2016 |
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.
Topics: Drug Design; Enzyme Inhibitors; Flavonoids; Fructose; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Liver; Molecular Structure | 2020 |
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins | 2020 |
Anti-phalloidine and anti-alpha-amanitine action of silybin in comparison with compounds similar to structural parts of silybin.
Topics: Alcohols; Amanitins; Animals; Catechin; Cinnamates; Female; Flavonoids; Flavonols; Male; Mice; Oligopeptides; Phalloidine; Phenols; Quercetin; Silymarin; Structure-Activity Relationship | 1978 |
[Chemical constituents of Bauhinia hupehara Craib].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromones; Drugs, Chinese Herbal; Fabaceae; Flavonoids; Flavonols; Plants, Medicinal; Quercetin | 1992 |
High-performance liquid chromatographic method for the determination of mangiferin, likviritin and dihydroquercetin in rat plasma and urine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Flavonols; Glucosides; Quercetin; Rats; Reproducibility of Results; Spectrophotometry, Ultraviolet; Xanthenes; Xanthones | 1992 |
Differential inhibition of proliferation of human squamous cell carcinoma, gliosarcoma and embryonic fibroblast-like lung cells in culture by plant flavonoids.
Topics: Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Flavones; Flavonoids; Flavonols; Glioma; Humans; Lung; Plant Extracts; Quercetin; Tumor Cells, Cultured | 1992 |
Antiproliferative effects of citrus flavonoids on a human squamous cell carcinoma in vitro.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Citrus; Drug Screening Assays, Antitumor; Flavones; Flavonoids; Flavonols; Humans; Quercetin | 1991 |
How flavonoids inhibit the generation of luminol-dependent chemiluminescence by activated human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Flavanones; Flavonoids; Flavonols; Hesperidin; Humans; Luminescent Measurements; Luminol; Luteolin; Neutrophils; Oxygen; Peroxidase; Pyridazines; Quercetin; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1990 |
The role of hydrogen peroxide in basophil histamine release and the effect of selected flavonoids.
Topics: Basophils; Calcium; Chamomile; Energy Metabolism; Eosinophils; Flavonoids; Flavonols; Histamine Release; Humans; Hydrogen Peroxide; Immunoglobulin E; Kinetics; Neutrophils; Oils, Volatile; Opsonin Proteins; Plant Extracts; Plants, Medicinal; Quercetin; Superoxides; Zymosan | 1986 |
Tumor promoter-induced basophil histamine release: effect of selected flavonoids.
Topics: Basophils; Chalcone; Flavones; Flavonoids; Flavonols; Histamine Release; Humans; Luteolin; Lyngbya Toxins; Quercetin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1987 |
Nedocromil sodium inhibits IgE- and IgG-related antigen-induced contraction in guinea-pig trachea.
Topics: Airway Resistance; Anaphylaxis; Animals; Benzoquinones; Chromones; Cromolyn Sodium; Flavonols; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Male; Nedocromil; Ovalbumin; Pyrilamine; Quercetin; Quinolones; Quinones; Trachea | 1989 |
[Fluid chromatography in supercritical conditions: a method potentially useful for flavonolignan analysis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Chromatography, Liquid; Flavonoids; Flavonols; Quercetin; Silymarin | 1989 |
Effect of antiviral substances on hepatitis A virus replication in vitro.
Topics: Antigens, Viral; Antiviral Agents; Atropine; Catechin; Cell Line; Cell Survival; Cystamine; Flavonols; Hepatitis A Antigens; Hepatovirus; Organoselenium Compounds; Protamines; Quercetin; Selenium; Virus Replication | 1987 |
An intensely sweet dihydroflavonol derivative based on a natural product lead compound.
Topics: Flavonoids; Flavonols; Humans; Molecular Conformation; Quercetin; Structure-Activity Relationship; Sweetening Agents | 1988 |
New metabolites of the naturally-occurring mutagen, quercetin, the pro-mutagen, rutin and of taxifolin.
Topics: Animals; Bile; Chemical Phenomena; Chemistry; Chromatography; Flavonoids; Flavonols; Mass Spectrometry; Quercetin; Rats; Rats, Inbred Strains; Rutin; Spectrophotometry, Ultraviolet | 1983 |
Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin.
Topics: Albumins; Animals; Antioxidants; Biological Availability; Biological Transport; Cecum; Chromatography, High Pressure Liquid; Diet; Feces; Flavonoids; Flavonols; Ileum; Intestinal Absorption; Lipoproteins; Luteolin; Male; Quercetin; Rats; Rats, Wistar; Rutin; Spectrometry, Fluorescence | 1995 |
Interaction of flavonoids with ascorbate and determination of their univalent redox potentials: a pulse radiolysis study.
Topics: Ascorbic Acid; Flavonoids; Flavonols; Hydrogen-Ion Concentration; Kaempferols; Kinetics; Luteolin; Molecular Structure; Oxidation-Reduction; Pulse Radiolysis; Quercetin; Rutin | 1995 |
[Analysis of dihydroquercetin in milk powder products using the HPLC method].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Dairy Products; Flavonols; Milk; Quercetin | 1995 |
Suppression of active oxygen-induced cytotoxicity by flavonoids.
Topics: Animals; Catechin; Cell Line; Colony-Forming Units Assay; Cricetinae; Cricetulus; Flavonoids; Flavonols; Hydrogen Peroxide; Kaempferols; Quercetin; Structure-Activity Relationship; Superoxides | 1993 |
Protection against oxidative damage by dihydroflavonols in Engelhardtia chrysolepis.
Topics: Animals; Antioxidants; Cattle; Flavonoids; Flavonols; Hemolysis; Humans; Lipid Peroxidation; Male; Microsomes, Liver; Mitochondria, Liver; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Superoxides; Trees | 1996 |
Effect of astilbin in tea processed from leaves of Engelhardtia chrysolepis on the serum and liver lipid concentrations and on the erythrocyte and liver antioxidative enzyme activities of rats.
Topics: Animals; Antioxidants; Beverages; Catalase; Erythrocytes; Flavonoids; Flavonols; Glutathione Peroxidase; Glutathione Reductase; Lipid Metabolism; Lipids; Liver; Male; Plant Leaves; Quercetin; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 1996 |
Inhibition of aldose reductase and sorbitol accumulation by astilbin and taxifolin dihydroflavonols in Engelhardtia chrysolepis.
Topics: Aldehyde Reductase; Animals; Erythrocytes; Flavonoids; Flavonols; Humans; Lens, Crystalline; Quercetin; Rats; Recombinant Proteins; Sorbitol; Trees | 1997 |
Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.
Topics: Dose-Response Relationship, Drug; Flavonoids; Flavonols; Luteolin; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein-Tyrosine Kinases; Quercetin; Structure-Activity Relationship | 1997 |
Induction of the anticarcinogenic marker enzyme, quinone reductase, in murine hepatoma cells in vitro by flavonoids.
Topics: Animals; Catechin; Chamomile; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Flavonols; Kaempferols; Liver Neoplasms, Experimental; Mice; NAD(P)H Dehydrogenase (Quinone); Oils, Volatile; Plants, Medicinal; Quercetin; Tumor Cells, Cultured | 1997 |
[Dihydroquercetin--a new antioxidant and biologically active food additive].
Topics: Animals; Antioxidants; Ascorbic Acid; Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Flavonols; In Vitro Techniques; Kinetics; Lipid Peroxidation; Luminescent Measurements; Quercetin; Rats | 1997 |
Antiradical and chelating effects in flavonoid protection against silica-induced cell injury.
Topics: Animals; Asbestos, Serpentine; Edetic Acid; Erythrocytes; Flavonoids; Flavonols; Free Radical Scavengers; Hemolysis; Humans; In Vitro Techniques; Iron Chelating Agents; Macrophages, Peritoneal; Oxidative Stress; Phagocytosis; Quercetin; Rats; Reactive Oxygen Species; Rutin; Thiobarbituric Acid Reactive Substances | 1998 |
Monohydroxyethylrutoside, a dose-dependent cardioprotective agent, does not affect the antitumor activity of doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Breast Neoplasms; Cardiomyopathies; Catechin; Chelation Therapy; Cystadenocarcinoma, Serous; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Electrocardiography; Female; Flavonoids; Flavonols; Free Radical Scavengers; Free Radicals; Humans; Hydroxyethylrutoside; Iron; Iron Chelating Agents; Kaempferols; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Ovarian Neoplasms; Quercetin; Razoxane; Rutin; Telemetry; Tumor Cells, Cultured; Weight Loss | 1997 |
The antioxidant properties of lycopene.
Topics: Animals; Antioxidants; Ascorbic Acid; beta Carotene; Butylated Hydroxytoluene; Carotenoids; Chick Embryo; Flavonols; Free Radicals; Kinetics; Lipid Peroxidation; Liposomes; Luminescent Measurements; Luminol; Lycopene; Quercetin; Rutin; Sodium Azide; Superoxide Dismutase; Uric Acid; Vitamin E | 1998 |
Anti- and pro-oxidative effects of flavonoids on metal-induced lipid hydroperoxide-dependent lipid peroxidation in cultured hepatocytes loaded with alpha-linolenic acid.
Topics: alpha-Linolenic Acid; Animals; Antioxidants; Cadmium; Copper; Flavonoids; Flavonols; Iron; Lipid Peroxidation; Lipid Peroxides; Liver; Male; Metals; Oxidants; Quercetin; Rats; Rats, Wistar; Vanadium | 1999 |
The flavanolignan silybin and its hemisynthetic derivatives, a novel series of potential modulators of P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Flavonoids; Flavonols; Magnetic Resonance Spectroscopy; Molecular Structure; Plants, Medicinal; Protein Binding; Quercetin; Silybum marianum; Silymarin | 2000 |
Regeneration of phenolic antioxidants from phenoxyl radicals: an ESR and electrochemical study of antioxidant hierarchy.
Topics: Antioxidants; Ascorbic Acid; Catechin; Chromatography, High Pressure Liquid; Electrochemistry; Electron Spin Resonance Spectroscopy; Flavonoids; Flavonols; Free Radicals; In Vitro Techniques; Luteolin; Oxidation-Reduction; Phenols; Quercetin; Vitamin E | 1999 |
Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds.
Topics: Acetaminophen; Acetates; Analgesics; Analgesics, Non-Narcotic; Animals; Aspirin; Edema; Flavonoids; Flavonols; Formaldehyde; Ibuprofen; Indomethacin; Male; Mice; Pain Measurement; Quercetin; Rats; Rats, Wistar | 2000 |
Dihydroquercetin as a means of antioxidative defence in rats with tetrachloromethane hepatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Flavonols; Lipid Peroxidation; Liver; Male; Quercetin; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2000 |
Effect of the combined action of flavonoids, ascorbate and alpha-tocopherol on peroxidation of phospholipid liposomes induced by Fe2+ ions.
Topics: Antioxidants; Ascorbic Acid; Cations, Divalent; Ferrous Compounds; Flavonols; Lipid Peroxidation; Liposomes; Phospholipids; Quercetin; Rutin; Vitamin E | 2000 |
Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid.
Topics: Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Dithiothreitol; Flavonols; Humans; Hydrolysis; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leupeptins; Liver; Quercetin; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Influence of metal ions on flavonoid protection against asbestos-induced cell injury.
Topics: Adsorption; Animals; Asbestos; Catechin; Cell Survival; Copper; Dose-Response Relationship, Drug; Flavonoids; Flavonols; Hemolysis; Inflammation; Ions; Iron; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Macrophages; Microsomes, Liver; NADP; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species; Rutin; Spectrophotometry; Tetrazolium Salts; Zinc | 2001 |
Degradation of quercetin and luteolin by Eubacterium ramulus.
Topics: Biodegradation, Environmental; Eubacterium; Expectorants; Feces; Flavonoids; Flavonols; Humans; Luteolin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Quercetin | 2001 |
Structure activity relationships for the chemical behaviour and toxicity of electrophilic quinones/quinone methides.
Topics: Benzoquinones; Flavonoids; Flavonols; Glutathione; HL-60 Cells; Humans; Indolequinones; Indoles; Luteolin; Molecular Structure; Mutagens; Oxidants; Quercetin; Quinones; Salmonella typhimurium; Structure-Activity Relationship | 2001 |
The regioselectivity of glutathione adduct formation with flavonoid quinone/quinone methides is pH-dependent.
Topics: Chromatography, High Pressure Liquid; Flavonoids; Flavonols; Glutathione; Hydrogen-Ion Concentration; Indolequinones; Indoles; Luteolin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Quercetin; Quinones | 2002 |
[Studies on the chemical constituents of Smilax glabra].
Topics: Drugs, Chinese Herbal; Flavonoids; Flavonols; Isoflavones; Liliaceae; Molecular Structure; Quercetin; Smilax | 1998 |
Flavonoids differentially regulate IFN gamma-induced ICAM-1 expression in human keratinocytes: molecular mechanisms of action.
Topics: Apigenin; Catechin; Cell Adhesion; Cell Line; Cells, Cultured; Coumaric Acids; Dose-Response Relationship, Drug; Flavonoids; Flavonols; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Jurkat Cells; Keratinocytes; Phosphorylation; Quercetin; RNA, Messenger; Tyrosine | 2002 |
Isolation and structure elucidation of radical scavengers from Thymus vulgaris leaves.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Cinnamates; Cymenes; Depsides; Flavonols; Free Radical Scavengers; Lithuania; Molecular Conformation; Molecular Structure; Monoterpenes; Picrates; Plant Leaves; Plants, Medicinal; Quercetin; Rosmarinic Acid; Structure-Activity Relationship; Terpenes; Thymus Plant | 2002 |
Functional expression and mutational analysis of flavonol synthase from Citrus unshiu.
Topics: Amino Acid Sequence; Amino Acid Substitution; Catalysis; Circular Dichroism; Citrus; DNA, Complementary; DNA, Plant; Enzyme Induction; Flavonoids; Flavonols; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Plant Proteins; Quercetin; Recombinant Fusion Proteins; Sequence Alignment; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature | 2002 |
Correction of haemorheological disturbances in myocardial infarction by diquertin and ascorbic acid.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Viscosity; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Erythrocyte Aggregation; Fibrinogen; Male; Myocardial Infarction; Phytotherapy; Quercetin; Rats; Rats, Wistar | 2003 |
Structure-dependent phytotoxicity of catechins and other flavonoids: flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
Topics: Catechin; Centaurea; Flavonoids; Flavonols; Kaempferols; Plant Extracts; Plant Proteins; Plant Roots; Plants; Quercetin; Structure-Activity Relationship | 2003 |
[Studies on the chemical constituents from Ampelopsis grossedentata].
Topics: Ampelopsis; Drugs, Chinese Herbal; Flavonoids; Flavonols; Molecular Structure; Plant Leaves; Plants, Medicinal; Quercetin; Sitosterols; Spectrophotometry, Ultraviolet; Spectroscopy, Near-Infrared; Stigmasterol | 2002 |
Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten.
Topics: Animals; Antioxidants; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Flavonoids; Flavonols; Fruit; Lipid Peroxidation; Neuroprotective Agents; Opuntia; Plant Extracts; Plant Stems; Quercetin; Rats; Rats, Sprague-Dawley | 2003 |
Structure-antioxidant activity relationships of flavonoids: a re-examination.
Topics: Amidines; Antioxidants; Ascorbic Acid; Biphenyl Compounds; Catechin; Edetic Acid; Flavonoids; Flavonols; Free Radicals; Iron; Kaempferols; Liposomes; Metmyoglobin; Picrates; Quercetin; Structure-Activity Relationship | 2002 |
Correction of the high blood viscosity syndrome by a mixture of Diquertin and Ascorbic Acid in vitro and in vivo.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Viscosity; Brain Ischemia; Drug Therapy, Combination; Erythrocyte Aggregation; Fibrinogen; Male; Phytotherapy; Quercetin; Rats; Rats, Wistar | 2003 |
Extraction of nutraceuticals from milk thistle: part II. Extraction with organic solvents.
Topics: Acetone; Acetonitriles; Ethanol; Flavonols; Methanol; Quercetin; Seeds; Silybum marianum; Silymarin; Solvents | 2003 |
[Studies on chemical constituents of Choerospondias axillaris].
Topics: Anacardiaceae; Fatty Alcohols; Flavonols; Fruit; Plants, Medicinal; Quercetin; Stearic Acids | 2003 |
Effect of ascovertin on morphofunctional changes in the ovaries in monopolar coagulation.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Viscosity; Drug Combinations; Erythrocyte Aggregation; Erythrocytes; Fallopian Tubes; Female; Flavonols; Gynecologic Surgical Procedures; Hematocrit; Ovarian Diseases; Ovary; Postoperative Period; Quercetin; Rats | 2003 |
The toxicity and metabolism of dihydroquercetin.
Topics: Flavonoids; Humans; Quercetin; Vitamins | 1958 |
Flavonoid dihydroquercetin, unlike quercetin, fails to inhibit expression of heat shock proteins under conditions of cellular stress.
Topics: Animals; Cell Line; Cell Size; Endothelial Cells; Flavonoids; Flavonols; Gene Expression Regulation; Heat-Shock Response; HSP70 Heat-Shock Proteins; Mice; Molecular Structure; Quercetin | 2003 |
Methylation of dihydroquercetin acetates: synthesis of 5-O-methyldihydroquercetin.
Topics: Acetates; Flavonols; Indicators and Reagents; Methylation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Quercetin; Stereoisomerism | 2003 |
A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production.
Topics: Administration, Oral; Animals; Anthocyanins; Anti-Inflammatory Agents; Apigenin; Cells, Cultured; Ear, External; Edema; Flavonoids; Flavonols; Lipopolysaccharides; Luteolin; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Quercetin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
Silymarin extraction from milk thistle using hot water.
Topics: Biotechnology; Flavonols; Hot Temperature; Kinetics; Models, Chemical; Quercetin; Silybin; Silybum marianum; Silymarin; Solvents; Temperature; Time Factors; Water | 2004 |
Prevention of macrophage adhesion molecule-1 (Mac-1)-dependent neutrophil firm adhesion by taxifolin through impairment of protein kinase-dependent NADPH oxidase activation and antagonism of G protein-mediated calcium influx.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cell Adhesion; Cell Adhesion Molecules; Enzyme Activation; Flavonols; Free Radicals; GTP-Binding Proteins; Humans; Macrophage-1 Antigen; Mitogen-Activated Protein Kinases; NADPH Oxidases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Quercetin; Reactive Oxygen Species; Up-Regulation; Xanthine Oxidase | 2004 |
Experimental evidence that flavonoid metal complexes may act as mimics of superoxide dismutase.
Topics: Catechin; Copper; Dose-Response Relationship, Drug; Flavonoids; Flavonols; Iron; Ligands; Light; Luteolin; Models, Chemical; Nitroblue Tetrazolium; Oxygen; Quercetin; Reactive Oxygen Species; Riboflavin; Rutin; Superoxide Dismutase; Superoxides; Time Factors; Ultraviolet Rays | 2004 |
Mechanisms underlying diquertin-mediated regulation of neutrophil function in patients with non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Antioxidants; Case-Control Studies; Diabetes Mellitus, Type 2; Humans; Hypochlorous Acid; In Vitro Techniques; Lipid Peroxidation; Male; Middle Aged; Neutrophils; Quercetin; Superoxides | 2004 |
Inhibitory activity of diacylglycerol acyltransferase (DGAT) and microsomal triglyceride transfer protein (MTP) by the flavonoid, taxifolin, in HepG2 cells: potential role in the regulation of apolipoprotein B secretion.
Topics: Acyltransferases; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins B; Carcinoma, Hepatocellular; Carrier Proteins; Diacylglycerol O-Acyltransferase; Enzyme-Linked Immunosorbent Assay; Flavonols; Humans; Liver Neoplasms; Quercetin; Tumor Cells, Cultured | 2004 |
Effects of flavonoids on the resistance of microsomes to lipid peroxidation in vitro and ex vivo.
Topics: Animals; Antioxidants; Flavonoids; Flavonols; Larix; Lipid Peroxidation; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Plant Extracts; Quercetin; Rats; Rats, Wistar; Silybin; Silybum marianum; Silymarin; Thiobarbituric Acid Reactive Substances; Vitis | 2003 |
The interaction of flavonoids with mitochondria: effects on energetic processes.
Topics: Adenosine Triphosphate; Animals; Calcium; Catechin; Cell Respiration; Flavonoids; Flavonols; Intracellular Membranes; Luminescent Measurements; Male; Membrane Fluidity; Mitochondria, Liver; Polarography; Quercetin; Rats; Rats, Wistar; Structure-Activity Relationship | 2005 |
[Clinical efficacy of a novel hemorheological drug ascovertin in patients with vascular encephalopathy].
Topics: Aged; Antioxidants; Ascorbic Acid; Blood Viscosity; Drug Combinations; Erythrocyte Aggregation; Erythrocyte Deformability; Flavonols; Headache; Hemorheology; Humans; Intracranial Arteriosclerosis; Lipid Peroxidation; Middle Aged; Neuropsychological Tests; Quercetin; Sleep Wake Disorders; Tinnitus; Vertigo | 2004 |
Structure-property studies on the antioxidant activity of flavonoids present in diet.
Topics: Antioxidants; Catechin; Deoxyguanosine; Diet; Flavonoids; Flavonols; Oxidation-Reduction; Quercetin; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 2005 |
Taxifolin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-oxidative effect and modulation of NF-kappa B activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Brain Ischemia; Cerebral Cortex; Cyclooxygenase 2; Flavonols; Intercellular Adhesion Molecule-1; Leukocytes; Macrophage-1 Antigen; Male; Microglia; Molecular Structure; Neutrophils; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Quercetin; Rats; Rats, Long-Evans; Reactive Oxygen Species; Reperfusion Injury | 2006 |
Effect of natural antioxidants on antioxidant activity and lipid peroxidation in eye tissue of rabbits with chemical burns.
Topics: Animals; Antioxidants; Aqueous Humor; Burns, Chemical; Eye; Eye Burns; Ginkgo biloba; Lipid Peroxidation; Malondialdehyde; Naphthoquinones; Phytotherapy; Quercetin; Rabbits; Retina; Vitreous Body | 2005 |
[The influence of antioxidants on morphological structure of internal organs of rats in acute hypoxia].
Topics: Anaerobiosis; Animals; Antioxidants; Brain; Flavonols; Heart; Liver; Male; Myocardium; Quercetin; Rats; Rats, Inbred Strains | 2005 |
[Morphological changes of rat ovaries after their monopolar coagulation and ascovertin correction].
Topics: Animals; Antioxidants; Ascorbic Acid; Drug Combinations; Electrocoagulation; Female; Flavonols; Ovary; Quercetin; Rats; Regeneration | 2005 |
Flavonoid 3'-O-methyltransferase from rice: cDNA cloning, characterization and functional expression.
Topics: Amino Acid Sequence; Caffeic Acids; Cloning, Molecular; DNA, Complementary; Escherichia coli; Flavanones; Flavonoids; Flavonols; Gene Expression Regulation; Luteolin; Molecular Sequence Data; Oryza; Protein O-Methyltransferase; Quercetin; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity; Triticum; Zea mays | 2006 |
[Studies on the flavonoids in stem of Rhododendron anthopogonoide II].
Topics: Flavonoids; Flavonols; Galactosides; Plant Leaves; Plant Stems; Plants, Medicinal; Quercetin; Rhododendron | 2005 |
Gene characterization, analysis of expression and in vitro synthesis of dihydroflavonol 4-reductase from [Citrus sinensis (L.) Osbeck].
Topics: Alcohol Oxidoreductases; Anthocyanins; Base Sequence; Blotting, Southern; Citrus sinensis; Cloning, Molecular; DNA, Complementary; Flavonols; Gene Expression Regulation, Plant; Genomics; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Phenotype; Pigmentation; Quercetin; Sequence Homology, Amino Acid; Substrate Specificity | 2006 |
Effect of ascovertin on morphological changes in rat retina exposed to high-intensity light.
Topics: Animals; Ascorbic Acid; Flavonols; Free Radicals; Light; Male; Quercetin; Radiation Injuries, Experimental; Rats; Retina; Time Factors | 2005 |
Influence of silymarin and its flavonolignans on H(2)O(2)-induced oxidative stress in human keratinocytes and mouse fibroblasts.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Flavonolignans; Flavonols; Humans; Hydrogen Peroxide; Keratinocytes; Mice; Mice, Inbred BALB C; Oxidants; Oxidative Stress; Phytotherapy; Plant Extracts; Protective Agents; Quercetin; Silybin; Silymarin | 2006 |
Differential effects of flavonoids on bovine kidney low molecular mass protein tyrosine phosphatase.
Topics: Animals; Cattle; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Flavonoids; Flavonols; Hydrogen-Ion Concentration; Hydrolysis; Kidney; Kinetics; Models, Chemical; Molecular Weight; Protein Tyrosine Phosphatases; Quercetin | 2006 |
Novel transgenic rice overexpressing anthocyanidin synthase accumulates a mixture of flavonoids leading to an increased antioxidant potential.
Topics: Amino Acid Sequence; Anthocyanins; Antioxidants; Catalysis; Flavonoids; Flavonols; Molecular Sequence Data; Oryza; Oxygenases; Plants, Genetically Modified; Quercetin; Zea mays | 2007 |
Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system.
Topics: Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Flavonols; Glycerides; Hemolysis; In Vitro Techniques; Molecular Structure; Poloxamer; Polyethylene Glycols; Protective Agents; Quercetin; Rabbits; Silybin; Silymarin; Solubility; Technology, Pharmaceutical; Time Factors | 2007 |
[Studies on chemical constituents of Cercis chinensis].
Topics: Fabaceae; Flavonols; Plant Bark; Plants, Medicinal; Quercetin; Triterpenes | 2006 |
Inhibitory compound of tyrosinase activity from the sprout of Polygonum hydropiper L. (Benitade).
Topics: Arbutin; Chemical Fractionation; Enzyme Inhibitors; Flavonols; Magnetic Resonance Spectroscopy; Molecular Structure; Monophenol Monooxygenase; Plant Shoots; Polygonum; Pyrones; Quercetin; Spectrometry, Mass, Electrospray Ionization | 2007 |
The chemopreventive effect of taxifolin is exerted through ARE-dependent gene regulation.
Topics: Antineoplastic Agents; Antioxidants; Flavonols; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Targeting; Genes, Reporter; HCT116 Cells; Humans; Luciferases; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Oligonucleotide Array Sequence Analysis; Plants, Medicinal; Polymerase Chain Reaction; Quercetin; Response Elements | 2007 |
Kinetic model for the antiradical activity of the isolated p-catechol group in flavanone type structures using the free stable radical 2,2-diphenyl-1-picrylhydrazyl as the antiradical probe.
Topics: Biphenyl Compounds; Catechols; Flavanones; Flavonols; Free Radical Scavengers; Kinetics; Methanol; Picrates; Quercetin; Solvents | 2007 |
Use of natural antioxidants for the correction of changes in general and local parameters of lipid peroxidation and antioxidant defense system during experimental eye burn.
Topics: Animals; Antioxidants; Burns, Chemical; Eye Burns; Ginkgo biloba; Lipid Peroxidation; Naphthoquinones; Phytotherapy; Plasma; Quercetin; Rabbits; Tears | 2006 |
Biotransformation of (+)-catechin into taxifolin by a two-step oxidation: primary stage of (+)-catechin metabolism by a novel (+)-catechin-degrading bacteria, Burkholderia sp. KTC-1, isolated from tropical peat.
Topics: Biotransformation; Burkholderia; Catechin; Flavonols; Oxidation-Reduction; Quercetin; Soil Microbiology; Species Specificity | 2008 |
Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: lack of association between antioxidant and lipoxygenase inhibitory activity.
Topics: Anti-Inflammatory Agents; Antioxidants; Arachidonate 5-Lipoxygenase; Cells, Cultured; Dinoprostone; Epoxide Hydrolases; F2-Isoprostanes; Flavonols; Humans; Kaempferols; Leukotriene B4; Lipoproteins, LDL; Luteolin; Monocytes; Neutrophils; Quercetin | 2008 |
Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells.
Topics: Antioxidants; Apigenin; Blotting, Western; Cell Survival; Cytokines; Flavonoids; Flavonols; Glutathione; Hepatocytes; Humans; Inflammation; Kaempferols; Liver; Oxidation-Reduction; Quercetin; Reactive Nitrogen Species; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2008 |
Effects of carovertin on the reaction of retinal pigmented epithelium and radial glia to bright light.
Topics: Animals; Ascorbic Acid; beta Carotene; Flavonols; Light; Male; Neuroglia; Pigment Epithelium of Eye; Quercetin; Rats | 2007 |
Flavonoids, taxifolin and luteolin attenuate cellular melanogenesis despite increasing tyrosinase protein levels.
Topics: Animals; Cell Line, Tumor; Flavonoids; Luteolin; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Quercetin | 2008 |
Acceleration of fibril formation and thermal stabilization of collagen fibrils in the presence of taxifolin (dihydroquercetin).
Topics: Animals; Calorimetry, Differential Scanning; Collagen Type I; Drug Stability; Hot Temperature; Microscopy, Electron; Quercetin; Rats; Thermodynamics | 2007 |
Taxifolin glycoside inhibits dendritic cell responses stimulated by lipopolysaccharide and lipoteichoic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Calcium; Dendritic Cells; Dose-Response Relationship, Drug; Female; Interleukin-12; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide; Quercetin; Reactive Oxygen Species; Spleen; Teichoic Acids; Tumor Necrosis Factor-alpha | 2008 |
In vive study of dihydroquercetin genotoxicity.
Topics: Animals; Bone Marrow Cells; Chromosome Aberrations; Comet Assay; DNA Damage; Female; Male; Mice; Mice, Inbred C57BL; Quercetin | 2008 |
Effect of Pinus massoniana bark extract on IFN-gamma-induced ICAM-1 expression in HaCaT human keratinocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Proliferation; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Keratinocytes; Pinus; Plant Bark; Plant Extracts; Quercetin; RNA, Messenger; Skin | 2009 |
Determination and pharmacokinetic study of taxifolin in rabbit plasma by high-performance liquid chromatography.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Calibration; Chromatography, High Pressure Liquid; Female; Genistein; Hydrolysis; Injections, Intravenous; Larix; Lipids; Male; Phytoestrogens; Plant Extracts; Quercetin; Rabbits | 2009 |
Screening of flavonoids as candidate antibiotics against Enterococcus faecalis.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Algorithms; Anti-Bacterial Agents; Arginine; Enterococcus faecalis; Escherichia coli; Flavanones; Microbial Sensitivity Tests; Phenylalanine; Quercetin; Structure-Activity Relationship; Vancomycin Resistance | 2009 |
Stereospecific high-performance liquid chromatography of taxifolin, applications in pharmacokinetics, and determination in tu fu ling (Rhizoma smilacis glabrae) and apple (Malus x domestica).
Topics: Animals; Chromatography, High Pressure Liquid; Malus; Quercetin; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Smilax; Stereoisomerism | 2009 |
Comparative mutagenic effects of structurally similar flavonoids quercetin and taxifolin on tester strains Salmonella typhimurium TA102 and Escherichia coli WP-2 uvrA.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Deferoxamine; Edetic Acid; Escherichia coli; Iron; Iron Chelating Agents; Liver Extracts; Microbial Sensitivity Tests; Mutagenesis; Mutagenicity Tests; Mutation; NADP; Quercetin; Rats; Salmonella typhimurium; Superoxide Dismutase | 2009 |
Dihydroquercetin (taxifolin) and other flavonoids as inhibitors of free radical formation at key stages of apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Chromans; Cytochromes c; Dose-Response Relationship, Drug; Flavonoids; Free Radicals; Liver; Molecular Structure; Peroxidase; Quercetin; Rutin; Superoxides | 2009 |
Nanodispersions of taxifolin: impact of solid-state properties on dissolution behavior.
Topics: Chemistry, Pharmaceutical; Drug Carriers; Freeze Drying; Molecular Structure; Nanoparticles; Nanotechnology; Particle Size; Povidone; Quercetin; Technology, Pharmaceutical | 2009 |
A highly sensitive and robust UPLC-MS with electrospray ionization method for quantitation of taxifolin in rat plasma.
Topics: Animals; Chromatography, Liquid; Quercetin; Rats; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2009 |
Permeation of astilbin and taxifolin in Caco-2 cell and their effects on the P-gp.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; Biological Availability; Biological Transport; Blotting, Western; Caco-2 Cells; Dose-Response Relationship, Drug; Flavonols; Humans; Permeability; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; Temperature; Up-Regulation | 2009 |
Influence of exogenous salicylic acid on flavonolignans and lipoxygenase activity in the hairy root cultures of Silybum marianum.
Topics: Antioxidants; Cell Culture Techniques; Flavonolignans; Linoleic Acid; Lipoxygenase; Plant Roots; Quercetin; Salicylic Acid; Silybin; Silybum marianum; Silymarin | 2009 |
Comparison of quercetin and dihydroquercetin: antioxidant-independent actions on erythrocyte and platelet membrane.
Topics: Adenosine Diphosphate; Amidines; Antioxidants; Blood Platelets; Cell Membrane; Erythrocyte Membrane; Hemolysis; Humans; Oxidants; Platelet Aggregation; Quercetin; Superoxides; Type C Phospholipases | 2009 |
Effects of Pinus brutia bark extract and Pycnogenol in a rat model of carrageenan induced inflammation.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Flavonoids; Inflammation; Male; Phytotherapy; Pinus; Plant Bark; Plant Extracts; Quercetin; Rats; Rats, Wistar | 2009 |
A fragmentation study of dihydroquercetin using triple quadrupole mass spectrometry and its application for identification of dihydroflavonols in Citrus juices.
Topics: Beverages; Citrus; Flavonols; Mass Spectrometry; Quercetin | 2009 |
Effect of liposomes containing antioxidant, phospholipid, and amino acid on skin regeneration after chemical burn.
Topics: Acetic Acid; Animals; Antioxidants; Burns, Chemical; Glycine; Hair Follicle; Lecithins; Liposomes; Male; Quercetin; Rats; Rats, Wistar; Regeneration; Sebaceous Glands; Skin; Time Factors; Wound Healing | 2009 |
Structure and antioxidant activity of brominated flavonols and flavanones.
Topics: Bromates; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Flavonols; Free Radical Scavengers; Molecular Structure; Oxidants; Quercetin; Rutin; Spectrometry, Mass, Electrospray Ionization | 2009 |
Constitutive and aluminium-induced patterns of phenolic compounds in two maize varieties differing in aluminium tolerance.
Topics: Aluminum; Caffeic Acids; Catechin; Catechols; Malondialdehyde; Phenols; Plant Roots; Quercetin; Zea mays | 2009 |
Peroxidation processes in rats during the delayed period after chronic administration of dihydroquercetin.
Topics: Analysis of Variance; Animals; Antioxidants; Ascorbic Acid; Lipid Peroxidation; Male; Quercetin; Rats | 2009 |
[Studies on the chemical constituents in ethyl acetate extraction from the fruit of Polygonum orientale].
Topics: Acetates; Flavonols; Fruit; Kaempferols; Magnetic Resonance Spectroscopy; Molecular Structure; Plants, Medicinal; Polygonum; Quercetin; Spectrophotometry, Ultraviolet | 2009 |
Effect of taxifolin glycoside on atopic dermatitis-like skin lesions in NC/Nga mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclopropanes; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Eosinophils; Female; Glycosides; Immunoglobulin E; Inflammation; Mice; Nitric Oxide Synthase Type II; Plant Extracts; Plant Roots; Quercetin; Rhododendron; Skin | 2010 |
Substituted pyrazinecarboxamides as abiotic elicitors of flavolignan production in Silybum marianum (L.) gaertn cultures in vitro.
Topics: Flavonolignans; Pyrazines; Quercetin; Silybum marianum; Tissue Culture Techniques | 2010 |
[Comparative pharmacokinetics of dihydroquercetin in rats upon peroral administration of a parent compound and liposomal flamen D].
Topics: Animals; Liposomes; Male; Quercetin; Rats | 2010 |
[Beneficial action of the liposomal form of dihydroquercetin on the process of skin regeneration after thermal burn].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Burns; Flavonoids; Liposomes; Male; Quercetin; Rats; Rats, Wistar; Skin; Wound Healing | 2010 |
[Study on HPLC-FPS of raw and processed fructus polygoni orientalis].
Topics: Chromatography, High Pressure Liquid; Drug Contamination; Drugs, Chinese Herbal; Plant Extracts; Quality Control; Quercetin; Reference Standards; Spectrometry, Mass, Electrospray Ionization | 2010 |
[Dihydroflavones in Rhododendron concinnum].
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Chromones; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Quercetin; Rhododendron; Silica Gel; Silicon Dioxide | 2010 |
[Anticoagulant activity of extracts from cedar bark, anthocyanidins of spruce and birch bark, and cellulose of aspen, fir, and wheat straw].
Topics: Abies; Anthocyanins; Anticoagulants; Antithrombins; Blood Coagulation; Cedrus; Dose-Response Relationship, Drug; Humans; Picea; Plant Bark; Plant Extracts; Quercetin; Triticum | 2010 |
Plasma protein binding of polyphenols from maritime pine bark extract (USP).
Topics: Blood Proteins; Buffers; Calibration; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Humans; Hydrogen Bonding; Models, Chemical; Phenols; Pinus; Plant Extracts; Polyphenols; Protein Binding; Quercetin; Regression Analysis; Ultrafiltration | 2011 |
[Study on the chemical constituents from Sarcopyramis nepalensis].
Topics: Caffeic Acids; Cinnamates; Ellagic Acid; Flavonoids; Kaempferols; Melastomataceae; Molecular Structure; Plants, Medicinal; Quercetin; Resins, Synthetic | 2010 |
Stability of Pycnogenol® as an ingredient in fruit juices subjected to in vitro gastrointestinal digestion.
Topics: Ananas; Beverages; Biflavonoids; Caffeic Acids; Catechin; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Digestion; Flavonoids; Food, Fortified; Fruit; Gallic Acid; In Vitro Techniques; Phenols; Pinus; Plant Bark; Plant Extracts; Plant Preparations; Polyphenols; Proanthocyanidins; Quercetin | 2011 |
[Study on the chemical constituents of Cudrania tricuspidata].
Topics: Flavanones; Moraceae; Plant Extracts; Plant Roots; Plant Stems; Quercetin; Sterols | 2010 |
[Antiproliferative and antioxidant activity of new dihydroquercetin derivatives].
Topics: Animals; Animals, Newborn; Antioxidants; Bone Marrow; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fibroblasts; Humans; Lipid Peroxides; Quercetin; Rats; Structure-Activity Relationship | 2010 |
Effects of a nanocomplex containing antioxidant, lipid, and amino acid on thermal burn wound surface.
Topics: Amino Acids; Animals; Antioxidants; Burns; Lecithins; Liposomes; Male; Nanoparticles; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Wound Healing | 2010 |
Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by phenolic compounds from roots of Rhododendron mucronulatum.
Topics: Anti-Inflammatory Agents; Antioxidants; Arabinose; Biflavonoids; Catechin; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Glucosides; Humans; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Plant Roots; Proanthocyanidins; Quercetin; Rhododendron | 2011 |
A new chromone derivative from Berchemia lineata.
Topics: Catechin; Chromones; Flavanones; Flavonoids; Molecular Structure; Plant Roots; Plants, Medicinal; Quercetin; Rhamnaceae | 2010 |
Stereospecific pharmacokinetics of racemic homoeriodictyol, isosakuranetin, and taxifolin in rats and their disposition in fruit.
Topics: Animals; Area Under Curve; Chromatography, High Pressure Liquid; Drug Stability; Flavones; Flavonoids; Fruit; Half-Life; Male; Molecular Structure; Quercetin; Rats; Rats, Sprague-Dawley; Serum; Stereoisomerism; Urine | 2011 |
Molecular characterization and expression analysis of dihydroflavonol 4-reductase (DFR) gene in Saussurea medusa.
Topics: Alcohol Oxidoreductases; Base Sequence; Chromatography, High Pressure Liquid; Computational Biology; DNA Primers; DNA, Complementary; Endangered Species; Escherichia coli; Flavonoids; Flavonols; Flowers; Gene Expression Profiling; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Phylogeny; Quercetin; Real-Time Polymerase Chain Reaction; Saccharomyces cerevisiae; Saussurea; Sequence Analysis, DNA | 2012 |
Investigation of flavonoids bearing different substituents on ring C and their cu2+ complex binding with bovine serum albumin: structure-affinity relationship aspects.
Topics: Catechin; Chelating Agents; Copper; Energy Transfer; Flavonoids; Luteolin; Protein Binding; Quercetin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Structure-Activity Relationship | 2011 |
Contribution of flavonoids and catechol to the reduction of ICAM-1 expression in endothelial cells by a standardised Willow bark extract.
Topics: Acetates; Anti-Inflammatory Agents; Catechols; Cell Survival; Chemical Fractionation; Chromatography, High Pressure Liquid; Coumaric Acids; Endothelial Cells; Flavanones; Flavonoids; Humans; Intercellular Adhesion Molecule-1; Molecular Structure; Plant Bark; Plant Extracts; Quercetin; Salix; Tumor Necrosis Factor-alpha | 2012 |
The thermal and enzymatic taxifolin-alphitonin rearrangement.
Topics: Benzofurans; Catalysis; Circular Dichroism; Eubacterium; Isomerases; Molecular Structure; Quercetin; Stereoisomerism; Temperature | 2011 |
[Flavonoid correction of functional elasticity of erythrocyte membranes and hemorheological disorders during oxidative stress caused by chronic physical overstrain in mice].
Topics: Administration, Oral; Animals; Animals, Outbred Strains; Antioxidants; Blood Viscosity; Catalase; Elasticity; Erythrocyte Deformability; Erythrocyte Membrane; Erythrocytes; Lipid Peroxidation; Male; Malondialdehyde; Mice; Oxidative Stress; Physical Exertion; Quercetin | 2011 |
The influence of Cd²⁺, Hg²⁺ and Pb²⁺ on taxifolin binding to bovine serum albumin by spectroscopic methods: with the viewpoint of toxic ions/drug interference.
Topics: Binding, Competitive; Cadmium; Lead; Mercury; Models, Biological; Protein Binding; Protein Conformation; Quercetin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2012 |
Development of HPLC fingerprint for species differentiation and quality assessment of Rhizoma Smilacis Glabrae.
Topics: Chromatography, High Pressure Liquid; Flavonols; Glycosides; Quercetin; Resveratrol; Rhizome; Shikimic Acid; Stilbenes; Tandem Mass Spectrometry | 2013 |
Chemical constituents comparison between Rhizoma Smilacis Glabrae and Rhizoma Smilacis Chinae by HPLC-DAD-MS/MS.
Topics: Chromatography, High Pressure Liquid; Flavonols; Glycosides; Quercetin; Shikimic Acid; Tandem Mass Spectrometry | 2013 |
Quercetin, quercetin glycosides and taxifolin differ in their ability to induce AhR activation and CYP1A1 expression in HepG2 cells.
Topics: Cytochrome P-450 CYP1A1; Glucosides; Hep G2 Cells; Humans; Quercetin; Receptors, Aryl Hydrocarbon; Rutin | 2012 |
Efficacy of glucosamine alendronate alone & in combination with dihydroquercetin for treatment of osteoporosis in animal model.
Topics: Alendronate; Animals; Bone Density; Bone Density Conservation Agents; Calcium; Collagen Type I; Collagen Type I, alpha 1 Chain; Drug Synergism; Glucosamine; Humans; Male; Osteocalcin; Osteoporosis; Quercetin; Rats; Rats, Wistar | 2012 |
A theoretical study on cellular antioxidant activity of selected flavonoids.
Topics: Antioxidants; Flavonoids; Free Radicals; Luteolin; Models, Biological; Models, Molecular; Quercetin; Spectrophotometry, Ultraviolet; Thermodynamics | 2012 |
Dual inhibition of chaperoning process by taxifolin: molecular dynamics simulation study.
Topics: Binding Sites; Cell Cycle Proteins; Chaperonins; HSP90 Heat-Shock Proteins; Humans; Molecular Chaperones; Molecular Dynamics Simulation; Protein Binding; Quercetin | 2012 |
[Effect of the liposomal form of taxifolin complexes with metals of variable valence on skin regeneration after chemical burn].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns, Chemical; Coordination Complexes; Copper; Hair Follicle; Iron; Lipid Peroxidation; Liposomes; Male; Oxidation-Reduction; Polymerization; Quercetin; Rats; Rats, Wistar; Sebaceous Glands; Wound Healing | 2012 |
Biotransformation of flavonols and taxifolin in hepatocyte in vitro systems as determined by liquid chromatography with various stationary phases and electrospray ionization-quadrupole time-of-flight mass spectrometry.
Topics: Adult; Aged; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Flavonols; Hepatocytes; Humans; Male; Middle Aged; Quercetin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
Inhibition of melanin production by a combination of Siberian larch and pomegranate fruit extracts.
Topics: Cell Line; Cell Survival; Down-Regulation; Drug Combinations; Drug Synergism; Fruit; Gene Expression; gp100 Melanoma Antigen; Humans; Hydrolyzable Tannins; Larix; Lythraceae; MART-1 Antigen; Melanins; Melanocytes; Melanoma-Specific Antigens; Monophenol Monooxygenase; Plant Extracts; Quercetin; Transcription Factors | 2012 |
Antioxidant composition causes antiexsudorific effect in the model of chronic venous insufficiency.
Topics: Animals; Antioxidants; Chronic Disease; Edema; Hindlimb; Male; Muscle, Skeletal; Quercetin; Rats; Rats, Wistar; Statistics, Nonparametric; Thioctic Acid; Venous Insufficiency | 2011 |
Taxifolin suppresses UV-induced skin carcinogenesis by targeting EGFR and PI3K.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Transformation, Neoplastic; Disease Models, Animal; ErbB Receptors; Female; Mice; Mice, Knockout; Models, Molecular; Phosphatidylinositol 3-Kinases; Protein Structure, Quaternary; Quercetin; Signal Transduction; Skin Neoplasms; Ultraviolet Rays | 2012 |
Extraction of dihydroquercetin from Larix gmelinii with ultrasound-assisted and microwave-assisted alternant digestion.
Topics: Ethanol; Larix; Microwaves; Quercetin; Sound; Wood | 2012 |
Micronization of taxifolin by supercritical antisolvent process and evaluation of radical scavenging activity.
Topics: Free Radical Scavengers; Hot Temperature; Particle Size; Quercetin | 2012 |
[Effects of different processing on active components in fructus polygoni orientalis by HPLC analysis].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Hot Temperature; Plants, Medicinal; Polygonaceae; Pressure; Quality Control; Quercetin; Reproducibility of Results; Technology, Pharmaceutical | 2012 |
Identification and assay of 3'-O-methyltaxifolin by UPLC-MS in rat plasma.
Topics: Animals; Caco-2 Cells; Chromatography, High Pressure Liquid; Drug Stability; Humans; Isoflavones; Male; Mass Spectrometry; Quercetin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity | 2012 |
[Chemical constituents of ethyl acetate extract from Polygonum perfoliatum].
Topics: Acetates; Chromatography, High Pressure Liquid; Flavones; Furaldehyde; Molecular Structure; Plants, Medicinal; Polygonum; Quercetin | 2012 |
Effects of taxifolin on the activity of angiotensin-converting enzyme and reactive oxygen and nitrogen species in the aorta of aging rats and rats treated with the nitric oxide synthase inhibitor and dexamethasone.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Atherosclerosis; Dexamethasone; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Glucocorticoids; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitrogen; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species | 2013 |
Why is quercetin a better antioxidant than taxifolin? Theoretical study of mechanisms involving activated forms.
Topics: Antioxidants; Free Radicals; Hydrogen; Hydrogen Bonding; Models, Chemical; Molecular Structure; Oxidation-Reduction; Quantum Theory; Quercetin; Structure-Activity Relationship; Thermodynamics | 2013 |
Skin regeneration after chemical burn under the effect of taxifolin-based preparations.
Topics: Acetaldehyde; Animals; Burns, Chemical; Flavonoids; Hair Follicle; Liposomes; Male; Quercetin; Rats; Rats, Wistar; Regeneration; Sebaceous Glands; Skin; Wound Healing | 2012 |
Effects of novel quercetin derivatives on sarco/endoplasmic reticulum Ca2+-ATPase activity.
Topics: Animals; Antioxidants; Drug Interactions; Endoplasmic Reticulum; Enzyme Activation; Female; Muscle, Skeletal; Peroxynitrous Acid; Quercetin; Rabbits; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2012 |
Lipophilicity of flavonoid complexes with iron(II) and their interaction with liposomes.
Topics: Flavonoids; Iron; Liposomes; Models, Molecular; Octanols; Phosphatidylethanolamines; Quercetin; Spectrophotometry, Ultraviolet; Water | 2013 |
Taxifolin enhances andrographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation.
Topics: Apoptosis; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Diterpenes; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; M Phase Cell Cycle Checkpoints; Male; Microtubules; Mitosis; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quercetin | 2013 |
Macrophage biospecific extraction and HPLC-ESI-MSn analysis for screening immunological active components in Smilacis Glabrae Rhizoma.
Topics: Biological Factors; Cell Adhesion; Cell Movement; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Flavonols; Human Umbilical Vein Endothelial Cells; Humans; Macrophages; Medicine, Chinese Traditional; Quercetin; Rhizome; Shikimic Acid; Smilax; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Water | 2013 |
Dihydroquercetin (DHQ) induced HO-1 and NQO1 expression against oxidative stress through the Nrf2-dependent antioxidant pathway.
Topics: Antioxidant Response Elements; Antioxidants; Heme Oxygenase-1; Hep G2 Cells; Humans; Larix; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Plant Extracts; Quercetin; Signal Transduction; Transcriptional Activation; Up-Regulation | 2013 |
Influence on longevity of blueberry, cinnamon, green and black tea, pomegranate, sesame, curcumin, morin, pycnogenol, quercetin, and taxifolin fed iso-calorically to long-lived, F1 hybrid mice.
Topics: Animals; Blueberry Plants; Body Weight; Cinnamomum zeylanicum; Crosses, Genetic; Curcumin; Feeding Behavior; Female; Flavonoids; Flavonols; Hybridization, Genetic; Longevity; Lythraceae; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Quercetin; Sesamum; Tea | 2013 |
In vitro effects of myricetin, morin, apigenin, (+)-taxifolin, (+)-catechin, (-)-epicatechin, naringenin and naringin on cytochrome b5 reduction by purified NADH-cytochrome b5 reductase.
Topics: Animals; Apigenin; Catechin; Cattle; Cytochrome-B(5) Reductase; Cytochromes b5; Flavanones; Flavonoids; Microsomes, Liver; Protein Binding; Quercetin; Rabbits | 2013 |
Structure-activity relationship for (+)-taxifolin isolated from silymarin as an inhibitor of amyloid β aggregation.
Topics: Amyloid beta-Peptides; Peptide Fragments; Protein Multimerization; Protein Structure, Secondary; Quercetin; Silymarin; Structure-Activity Relationship | 2013 |
Effect of dihydroquercetin on the tone of isolated rat veins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Potassium Chloride; Quercetin; Rats; Rats, Wistar; Vasoconstriction | 2013 |
[Simultaneous determination of four flavones in root and stem of Cudrania tricuspidata and C. cochinchinensis by HPLC-DAD].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavones; Kaempferols; Methanol; Moraceae; Organ Specificity; Phosphoric Acids; Plant Roots; Plant Stems; Plants, Medicinal; Quercetin; Reproducibility of Results; Species Specificity | 2013 |
[Estimating ability of dihydroquercetin to inhibit oxidation of fibrinogen by ozone].
Topics: Animals; Fibrinogen; Humans; Oxidation-Reduction; Ozone; Quercetin | 2013 |
Enzyme-assisted extraction of cactus bioactive molecules under high hydrostatic pressure.
Topics: Aspergillus; Cellulases; Complement Activation; Ethnopharmacology; Free Radical Scavengers; Fungal Proteins; Hydrolysis; Hydrostatic Pressure; Immunologic Factors; Medicine, Kampo; Multienzyme Complexes; Opuntia; Plant Extracts; Plant Shoots; Polygalacturonase; Polysaccharides; Quercetin; Republic of Korea | 2014 |
Enhancing effect of a cysteinyl thiol on the antioxidant activity of flavonoids and identification of the antioxidative thiol adducts of myricetin.
Topics: Antioxidants; Catechin; Flavonoids; Oxidation-Reduction; Quercetin; Sulfhydryl Compounds | 2013 |
[Flavonoids from Humulus lupulus].
Topics: Dextrans; Drugs, Chinese Herbal; Flavanones; Flavonoids; Humulus; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Quercetin | 2013 |
Glucosylation of taxifolin with cultured plant cells.
Topics: Biotransformation; Cells, Cultured; Eucalyptus; Glycosylation; Quercetin | 2013 |
Molecular cloning and characterization of three genes encoding dihydroflavonol-4-reductase from Ginkgo biloba in anthocyanin biosynthetic pathway.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Anthocyanins; Base Sequence; Biocatalysis; Biosynthetic Pathways; Blotting, Western; Cloning, Molecular; Flavonoids; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Ginkgo biloba; Isoenzymes; Molecular Sequence Data; Multigene Family; Phylogeny; Plant Growth Regulators; Plant Proteins; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Ultraviolet Rays | 2013 |
Austrian pine phenolics are likely contributors to systemic induced resistance against Diplodia pinea.
Topics: Antifungal Agents; Ascomycota; Coumaric Acids; Lignin; Phenols; Phenotype; Pinus; Plant Diseases; Plant Immunity; Quercetin; Stilbenes | 2013 |
[Usage of flavonoids for effective correction of functional and structural breaches of erythrocytes membranes during an extraordinary physical strain in experiments].
Topics: Animals; Animals, Outbred Strains; Erythrocyte Membrane; Fatty Acids; Male; Membrane Lipids; Mice; Phospholipids; Physical Exertion; Quercetin; Sodium-Hydrogen Exchangers | 2013 |
LC-MS metabolic study on quercetin and taxifolin galloyl esters using human hepatocytes as toxicity and biotransformation in vitro cell model.
Topics: Adolescent; Animals; Biotransformation; Cells, Cultured; Chromatography, Liquid; Esters; Female; Gallic Acid; Hepatocytes; Humans; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Middle Aged; NIH 3T3 Cells; Quercetin; Tandem Mass Spectrometry | 2013 |
Quercitrin and taxifolin stimulate osteoblast differentiation in MC3T3-E1 cells and inhibit osteoclastogenesis in RAW 264.7 cells.
Topics: Animals; Biomarkers; Cell Differentiation; Cell Line; Cell Survival; Flavonoids; Gene Expression; Integrin-Binding Sialoprotein; Macrophages; Mice; Osteoblasts; Osteocalcin; Osteoclasts; Osteogenesis; Quercetin | 2013 |
Antitumour agents as inhibitors of tryptophan 2,3-dioxygenase.
Topics: Antineoplastic Agents; Catechols; Cell Line, Tumor; Chromones; Humans; Quercetin; Tryptophan Oxygenase | 2014 |
Taxifolin prevents diabetic cardiomyopathy in vivo and in vitro by inhibition of oxidative stress and cell apoptosis.
Topics: Angiotensin II; Animals; Apoptosis; Caspases; Cell Line; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Oxidative Stress; Quercetin; Rats; Reactive Oxygen Species; Streptozocin | 2014 |
Olive oil compounds inhibit vascular endothelial growth factor receptor-2 phosphorylation.
Topics: Cell Movement; Cell Proliferation; Cells, Cultured; Down-Regulation; Human Umbilical Vein Endothelial Cells; Humans; Neovascularization, Physiologic; Oleic Acid; Olive Oil; Phenylethyl Alcohol; Phosphorylation; Plant Extracts; Plant Oils; Protein Processing, Post-Translational; Quercetin; Vascular Endothelial Growth Factor Receptor-2 | 2014 |
[Determination of taxifolin in Polygonum orientale of different storage period].
Topics: Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Drugs, Chinese Herbal; Polygonum; Quercetin | 2013 |
Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin.
Topics: Antioxidants; Antiviral Agents; Apigenin; Cell Line; Chromones; Down-Regulation; Fatty Acids, Nonesterified; Hepacivirus; Humans; Kaempferols; Lipogenesis; Liver X Receptors; Morpholines; Orphan Nuclear Receptors; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quercetin; Reactive Nitrogen Species; Signal Transduction; Triglycerides; Virus Replication | 2014 |
Identification of quercitrin as a potential therapeutic agent for periodontal applications.
Topics: Adult; Anti-Bacterial Agents; Antioxidants; Cell Culture Techniques; Cell Survival; Cells, Cultured; Collagen; Collagen Type III; Decorin; Female; Fibroblasts; Flavonoids; Gingiva; Humans; Interleukin-6; Male; Matrix Metalloproteinase 1; Middle Aged; Quercetin; Reactive Oxygen Species; Staphylococcus epidermidis; Tissue Inhibitor of Metalloproteinase-1; Wound Healing; Young Adult | 2014 |
Adaptogenic effects of dihydroquercetin-chitosan composition during modeling of acute hypoxia.
Topics: Acute Disease; Animals; Chitosan; Hypoxia; Male; Models, Biological; Quercetin; Rats | 2014 |
Enhancement of solubility, antioxidant ability and bioavailability of taxifolin nanoparticles by liquid antisolvent precipitation technique.
Topics: Animals; Antioxidants; Biological Availability; Biphenyl Compounds; Chemical Precipitation; Drug Carriers; Drug Compounding; Ethanol; Female; Nanoparticles; Particle Size; Picrates; Quercetin; Rats, Sprague-Dawley; Solubility; Solvents; Surface Properties; Tissue Distribution; Water | 2014 |
Complex disruption effect of natural polyphenols on Bcl-2-Bax: molecular dynamics simulation and essential dynamics study.
Topics: Algorithms; bcl-2-Associated X Protein; Humans; Hydrophobic and Hydrophilic Interactions; Indoles; Kinetics; Molecular Conformation; Molecular Dynamics Simulation; Molecular Structure; Multiprotein Complexes; Polyphenols; Principal Component Analysis; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Quercetin | 2015 |
Neural cell activation by phenolic compounds from the Siberian larch (Larix sibirica).
Topics: Animals; Astrocytes; Butylene Glycols; Disease Models, Animal; Female; Larix; Lignans; Lignin; Male; Mice; Mice, Inbred C57BL; Models, Neurological; Molecular Structure; Naphthols; Neurites; Phenols; Quercetin; Schwann Cells; Stereoisomerism | 2014 |
[Study on characteristic HPLC fingerprint of Polygonum orientale inflorescence].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flowers; Plants, Medicinal; Polygonum; Quality Control; Quercetin; Reproducibility of Results | 2013 |
[Studies on optimizing extraction technics of flowers of Polygonum orientale by response surface methodology].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ethanol; Flowers; Linear Models; Plants, Medicinal; Polygonum; Quercetin; Technology, Pharmaceutical; Time Factors | 2014 |
Inhibition of insect glutathione S-transferase (GST) by conifer extracts.
Topics: Animals; Coleoptera; Enzyme Inhibitors; Fat Body; Gastrointestinal Tract; Glutathione Transferase; Insecticide Resistance; Insecticides; Larva; Lignans; Pesticide Synergists; Plant Extracts; Quercetin; Tracheophyta | 2014 |
Development of an ionic liquid-based microwave-assisted method for the extraction and determination of taxifolin in different parts of Larix gmelinii.
Topics: Anions; Biomass; Cations; Chemistry, Organic; Ionic Liquids; Larix; Microwaves; Plant Roots; Quercetin; Reference Standards; Regression Analysis; Reproducibility of Results; Seasons; Solvents; Time Factors; Wood; Xylem | 2014 |
Camel thorn extract reduces activity of angiotensin-converting enzyme in rat aorta increased during aging and treatment with NO-synthase inhibitor.
Topics: Aging; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Atherosclerosis; Flavanones; Glycosides; Male; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Plant Extracts; Quercetin; Rats; Rats, Wistar | 2014 |
The high water solubility of inclusion complex of taxifolin-γ-CD prepared and characterized by the emulsion solvent evaporation and the freeze drying combination method.
Topics: Animals; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Drug Compounding; Emulsions; Female; Freeze Drying; gamma-Cyclodextrins; Particle Size; Quercetin; Rats; Rats, Sprague-Dawley; Solubility; Solvents; Temperature; Water | 2014 |
Ultrasound-assisted extraction of arabinogalactan and dihydroquercetin simultaneously from Larix gmelinii as a pretreatment for pulping and papermaking.
Topics: Chromatography, High Pressure Liquid; Galactans; Larix; Paper; Quercetin; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Ultrasonics | 2014 |
In vivo assessment of the effect of taxifolin glycoside on atopic dermatitis-like skin lesions using biomedical tools in NC/Nga mice.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Immunoglobulin E; Mice; Quercetin; Water Loss, Insensible | 2015 |
Flavanonol taxifolin attenuates proteasome inhibition-induced apoptosis in differentiated PC12 cells by suppressing cell death process.
Topics: Animals; Apoptosis; Cell Death; Cell Differentiation; Flavonols; PC12 Cells; Proteasome Inhibitors; Quercetin; Rats; Reactive Oxygen Species | 2015 |
Effects of dihydroquercetin obtained from deodar (Cedrus deodara) on immune status of gilthead seabream (Sparus aurata L.).
Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cedrus; Diet; Dose-Response Relationship, Immunologic; Immunity, Cellular; Immunity, Humoral; Plant Extracts; Quercetin; Random Allocation; Sea Bream | 2015 |
Evaluation of dihydroquercetin-3-O-glucoside from Malbec grapes as copigment of malvidin-3-O-glucoside.
Topics: Anthocyanins; Color; Flavonols; Fruit; Glucosides; Humans; Hydroxybenzoates; Phenols; Pigments, Biological; Quercetin; Spectrophotometry; Thermodynamics; Vitis; Wine | 2015 |
Pro‑apoptotic effects of pycnogenol on HT1080 human fibrosarcoma cells.
Topics: Adult; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Fibrosarcoma; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Sequence Data; Plant Extracts; Quercetin; Signal Transduction; Young Adult | 2015 |
Dihydroquercetin effects on the morphology and antioxidant/prooxidant balance of the prostate in rats with sulpiride-induced benign hyperplasia.
Topics: Animals; Antioxidants; Histological Techniques; Male; Prostatic Hyperplasia; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species; Statistics, Nonparametric; Sulpiride | 2015 |
Effects of phytochemicals on in vitro anti-inflammatory activity of Bifidobacterium adolescentis.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Bifidobacterium; Catechin; Cell Line; Coculture Techniques; Dose-Response Relationship, Drug; Flavonoids; Glucosides; Lactic Acid; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Phytochemicals; Probiotics; Quercetin | 2015 |
Enzymatic polymerization of dihydroquercetin using bilirubin oxidase.
Topics: Antioxidants; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Polymerization; Polymers; Quercetin | 2015 |
Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin.
Topics: Acetylcholinesterase; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Isoenzymes; Molecular Structure; Quercetin; Structure-Activity Relationship | 2016 |
Dihydroquercetin (DHQ) ameliorated concanavalin A-induced mouse experimental fulminant hepatitis and enhanced HO-1 expression through MAPK/Nrf2 antioxidant pathway in RAW cells.
Topics: Animals; Antioxidants; Autoimmune Diseases; Cell Line; Concanavalin A; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Hepatitis; Humans; Immunity; Interferon-gamma; Macrophages; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Animal; NF-E2-Related Factor 2; Quercetin; Signal Transduction; Tumor Necrosis Factor-alpha | 2015 |
Taxifolin mitigates oxidative DNA damage in vitro and protects zebrafish (Danio rerio) embryos against cadmium toxicity.
Topics: Animals; Antioxidants; Cadmium; DNA Damage; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Embryonic Development; Gene Expression Regulation, Developmental; Lipid Peroxidation; Oxidative Stress; Quercetin; Zebrafish | 2015 |
Taxifolin protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload.
Topics: Angiotensin-Converting Enzyme 2; Animals; Cardiomegaly; Dose-Response Relationship, Drug; Electrocardiography; Fibrosis; Mice; Myocytes, Cardiac; Oxidative Stress; Peptidyl-Dipeptidase A; Quercetin; Reactive Oxygen Species; Signal Transduction | 2015 |
Formation of plasmonic silver nanoparticles by flavonoid reduction: A comparative study and application for determination of these substances.
Topics: Flavanones; Flavonoids; Metal Nanoparticles; Quercetin; Rutin; Silver; Spectrophotometry | 2015 |
Antioxidant activity of taxifolin: an activity-structure relationship.
Topics: Antioxidants; Dose-Response Relationship, Drug; Free Radicals; Lipid Peroxidation; Quercetin; Spectrophotometry; Structure-Activity Relationship | 2016 |
Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin.
Topics: Animals; Cell Line; Cytochrome P-450 CYP1A1; Free Radical Scavengers; Gene Expression Regulation; Heme Oxygenase-1; Hep G2 Cells; Humans; Mice; Quercetin | 2015 |
Flavonoids as Multi-target Inhibitors for Proteins Associated with Ebola Virus: In Silico Discovery Using Virtual Screening and Molecular Docking Studies.
Topics: Antiviral Agents; Ebolavirus; Flavonoids; Molecular Docking Simulation; Quercetin; Viral Proteins | 2016 |
Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Dietary Supplements; Disease Models, Animal; Lung; Male; Mangifera; Mice, Inbred ICR; Neutrophil Infiltration; Plant Extracts; Plant Leaves; Polyphenols; Pulmonary Fibrosis; Quercetin; Random Allocation; Respiratory Mucosa; Resveratrol; Stilbenes; Vitis; Xanthones | 2015 |
Taxifolin curbs NF-κB-mediated Wnt/β-catenin signaling via up-regulating Nrf2 pathway in experimental colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; beta Catenin; Carcinogens; Colon; Colonic Neoplasms; Humans; Intestinal Mucosa; Ligands; Male; Mast Cells; Mice; Molecular Docking Simulation; Neoplasm Proteins; NF-E2-Related Factor 2; NF-kappa B; Quercetin; Random Allocation; Wnt Signaling Pathway | 2015 |
Adenosine/guanosine preferring nucleoside ribohydrolase is a distinct, druggable antitrichomonal target.
Topics: Adenosine; Antitrichomonal Agents; Flavonoids; High-Throughput Screening Assays; N-Glycosyl Hydrolases; Quercetin; Small Molecule Libraries; Stereoisomerism; Trichomonas vaginalis | 2015 |
Virus-inhibiting activity of dihydroquercetin, a flavonoid from Larix sibirica, against coxsackievirus B4 in a model of viral pancreatitis.
Topics: Animals; Antiviral Agents; Dose-Response Relationship, Drug; Enterovirus B, Human; Female; Larix; Mice; Molecular Structure; Pancreas; Pancreatitis; Quercetin; Random Allocation; Ribavirin; Virus Replication | 2016 |
Thonningiiflavanonol A and thonningiiflavanonol B, two novel flavonoids, and other constituents of Ficus thonningii Blume (Moraceae).
Topics: Antioxidants; Ficus; Flavanones; Flavonoids; Gallic Acid; Genistein; Luteolin; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Parabens; Plant Bark; Plant Extracts; Plant Roots; Plant Stems; Quercetin; Sitosterols | 2016 |
Taxifolin and Fucoidin Abolish the Irradiation-Induced Increase in the Production of Reactive Oxygen Species in Rat Aorta.
Topics: Animals; Aorta; Cell Adhesion; Endothelium; Leukocytes; Male; Polysaccharides; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species; X-Rays | 2016 |
UHPLC-MS/MS Determination, Pharmacokinetic, and Bioavailability Study of Taxifolin in Rat Plasma after Oral Administration of its Nanodispersion.
Topics: Administration, Intravenous; Administration, Oral; Animals; Biological Availability; Chromatography, High Pressure Liquid; Humans; Inflammation; Liquid-Liquid Extraction; Parabens; Quercetin; Rats; Tandem Mass Spectrometry | 2016 |
[ANTIVIRAL ACTIVITY OF THE DIHYDROQUERCETIN DURING THE COXSACKIEVIRUS B4 REPLICATION IN VITRO].
Topics: Animals; Antioxidants; Antiviral Agents; Chlorocebus aethiops; Enterovirus B, Human; Larix; Quercetin; Vero Cells; Viral Load; Virus Replication | 2016 |
Artichoke and milk thistle pills and syrups as sources of phenolic compounds with antimicrobial activity.
Topics: Anti-Infective Agents; Antioxidants; Cynara scolymus; Dietary Supplements; Disaccharides; Escherichia coli; Flavonoids; Luteolin; Methicillin-Resistant Staphylococcus aureus; Phenol; Plant Preparations; Proteus mirabilis; Pseudomonas aeruginosa; Quercetin; Quinic Acid; Silybin; Silybum marianum; Silymarin; Vanillic Acid | 2016 |
Variation in the flavonolignan composition of fruits from different Silybum marianum chemotypes and suspension cultures derived therefrom.
Topics: Bulgaria; Cells, Cultured; Europe; Flavonols; Fruit; Lignin; Quercetin; Silybin; Silybum marianum; Silymarin; Stereoisomerism | 2016 |
Detection of 191 Taxifolin Metabolites and Their Distribution in Rats Using HPLC-ESI-IT-TOF-MS(n).
Topics: Animals; Chromatography, High Pressure Liquid; Male; Quercetin; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization | 2016 |
Enzymatic activity of cell-free extracts from Burkholderia oxyphila OX-01 bio-converts (+)-catechin and (-)-epicatechin to (+)-taxifolin.
Topics: Biotransformation; Burkholderia; Catechin; Oxygen; Quercetin; Stereoisomerism; Substrate Specificity | 2016 |
Dihydroquercetin Does Not Affect Age-Dependent Increase in Blood Pressure and Angiotensin-Converting Enzyme Activity in the Aorta of Hypertensive Rats.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Drug Evaluation, Preclinical; Heart Rate; Hypertension; Male; Peptidyl-Dipeptidase A; Quercetin; Rats, Inbred SHR; Rats, Inbred WKY | 2016 |
Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin.
Topics: Antioxidants; Catechin; Edetic Acid; Flavanones; Flavonoids; Quercetin; Structure-Activity Relationship | 2016 |
Concurrent Treatment with Taxifolin and Cilostazol on the Lowering of β-Amyloid Accumulation and Neurotoxicity via the Suppression of P-JAK2/P-STAT3/NF-κB/BACE1 Signaling Pathways.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cells, Cultured; Cilostazol; Down-Regulation; Drug Synergism; Janus Kinase 2; Mice; Neuroprotection; Neuroprotective Agents; NF-kappa B; Phosphorylation; Quercetin; Signal Transduction; STAT3 Transcription Factor; Tetrazoles | 2016 |
Modes of Hypotensive Action of Dihydroquercetin in Arterial Hypertension.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Erythrocyte Aggregation; Erythrocyte Deformability; Gastric Absorption; Heart Ventricles; Hematocrit; Hypertension; Male; Quercetin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tissue Culture Techniques; Vasodilation; Viscosity | 2017 |
Microbial production of astilbin, a bioactive rhamnosylated flavanonol, from taxifolin.
Topics: Antineoplastic Agents; Arabidopsis Proteins; Biosynthetic Pathways; Cell Line, Tumor; Cell Survival; Escherichia coli; Flavonols; Gene Knockout Techniques; Genetic Engineering; Glycosylation; Glycosyltransferases; Humans; Quercetin; Rhamnose | 2017 |
Taxifolin synergizes Andrographolide-induced cell death by attenuation of autophagy and augmentation of caspase dependent and independent cell death in HeLa cells.
Topics: Apoptosis; Autophagy; Caspases; Cell Death; Cell Proliferation; Diterpenes; Drug Synergism; HeLa Cells; Humans; Quercetin; Signal Transduction | 2017 |
Flavonoids from Agrimonia pilosa Ledeb: Free Radical Scavenging and DNA Oxidative Damage Protection Activities and Analysis of Bioactivity-Structure Relationship Based on Molecular and Electronic Structures.
Topics: Agrimonia; Catechin; DNA Damage; Flavonoids; Molecular Structure; Oxidative Stress; Plant Extracts; Quercetin; Rutin; Structure-Activity Relationship | 2017 |
The Phototoxic Potential of the Flavonoids, Taxifolin and Quercetin.
Topics: 3T3 Cells; Animals; Cells, Cultured; Culture Media; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Quercetin; Skin; Structure-Activity Relationship; Ultraviolet Rays | 2017 |
Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy.
Topics: Amyloid beta-Peptides; Animals; Cerebral Amyloid Angiopathy; Cerebrovascular Circulation; Disease Models, Animal; Humans; Male; Memory Disorders; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Nootropic Agents; Protein Aggregation, Pathological; Quercetin; Random Allocation; Receptor for Advanced Glycation End Products; Spatial Memory | 2017 |
Biotechnological Production of Dimethoxyflavonoids Using a Fusion Flavonoid O-Methyltransferase Possessing Both 3'- and 7-O-Methyltransferase Activities.
Topics: Escherichia coli; Flavanones; Flavonoids; Luteolin; Methylation; Methyltransferases; Molecular Structure; Quercetin | 2017 |
Dihydroquercetin Improves Microvascularization and Microcirculation in the Brain Cortex of SHR Rats during the Development of Arterial Hypertension.
Topics: Animals; Blood Pressure; Brain; Cerebral Cortex; Cerebrovascular Circulation; Hypertension; Microcirculation; Quercetin; Rats; Rats, Inbred WKY | 2017 |
Taxifolin enhances osteogenic differentiation of human bone marrow mesenchymal stem cells partially via NF-κB pathway.
Topics: Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Mesenchymal Stem Cells; Molecular Structure; NF-kappa B; Osteogenesis; Protein Transport; Quercetin; Signal Transduction; Structure-Activity Relationship | 2017 |
Restraining Pathogenicity in Candida albicans by Taxifolin as an Inhibitor of Ras1-pka Pathway.
Topics: Antifungal Agents; Binding Sites; Candida albicans; Candidiasis; Catalytic Domain; DNA-Binding Proteins; Fungal Proteins; HSP90 Heat-Shock Proteins; Humans; Hyphae; Molecular Docking Simulation; Molecular Dynamics Simulation; Quercetin; ras Proteins; Repressor Proteins; Transcription Factors | 2017 |
Taxifolin inhibits rat and human 11β-hydroxysteroid dehydrogenase 2.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Corticosterone; Glucocorticoids; Humans; Male; Quercetin; Rats; Rats, Sprague-Dawley | 2017 |
Taxifolin reduces the cholesterol oxidation product-induced neuronal apoptosis by suppressing the Akt and NF-κB activation-mediated cell death.
Topics: Animals; Apoptosis; Caspases; Cell Line, Tumor; Cholesterol; Glutathione; Humans; Ketocholesterols; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; NF-kappa B; Oxidation-Reduction; PC12 Cells; Proto-Oncogene Proteins c-akt; Quercetin; Rats; Reactive Oxygen Species | 2017 |
Taxifolin Activates the Nrf2 Anti-Oxidative Stress Pathway in Mouse Skin Epidermal JB6 P+ Cells through Epigenetic Modifications.
Topics: Animals; Antioxidants; Cell Line; CpG Islands; DNA Methylation; Epidermis; Epigenesis, Genetic; Gene Expression Regulation; Heme Oxygenase-1; Hep G2 Cells; Humans; Membrane Proteins; Mice; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Phorbol Esters; Quercetin; Sequence Analysis, DNA; Signal Transduction | 2017 |
Skin Penetration Enhancement by Natural Oils for Dihydroquercetin Delivery.
Topics: Administration, Cutaneous; Anti-Inflammatory Agents, Non-Steroidal; Fatty Acids; Ions; Mass Spectrometry; Plant Oils; Quercetin; Skin; Skin Absorption; Skin Physiological Phenomena | 2017 |
Changes in Sympathetic Innervation of the Heart in Rats with Experimental Myocardial Infarction. Effect of Semax.
Topics: Adrenocorticotropic Hormone; Animals; Male; Myocardial Infarction; Peptide Fragments; Prostate; Prostatitis; Quercetin; Rats; Rats, Wistar; Sympathetic Nervous System | 2017 |
Changes in the Proteome of HaCaT Keratinocytes Induced by Cytotoxic Substance Triton X-100.
Topics: Analysis of Variance; Animals; Humans; Keratinocytes; Male; Mice; Octoxynol; Oxidative Stress; Prostatitis; Proteome; Quercetin | 2017 |
Homogenization-assisted cavitation hybrid rotation extraction and macroporous resin enrichment of dihydroquercetin from Larix gmelinii.
Topics: Adsorption; Chemical Fractionation; Ethanol; Kinetics; Larix; Quercetin; Resins, Synthetic; Rotation | 2017 |
Inhibition of HEWL fibril formation by taxifolin: Mechanism of action.
Topics: Binding Sites; Cell Line; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Humans; Hydrophobic and Hydrophilic Interactions; Microscopy, Atomic Force; Molecular Docking Simulation; Neurofibrils; Quercetin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2017 |
Heteropterys tomentosa A. Juss: Toxicological and adaptogenic effects in experimental models.
Topics: Animals; Behavior, Animal; CHO Cells; Cricetulus; Dietary Supplements; Ethnopharmacology; Fatigue; Female; Flavonols; Male; Malpighiaceae; Medicine, Traditional; Mice; Performance-Enhancing Substances; Physical Exertion; Plant Extracts; Plant Roots; Quercetin; Random Allocation; Rats, Wistar; Toxicity Tests, Acute; Toxicity Tests, Subchronic | 2017 |
Dihydroquercetin ameliorated acetaminophen-induced hepatic cytotoxicity via activating JAK2/STAT3 pathway and autophagy.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Cells, Cultured; Hepatocytes; Janus Kinase 2; Liver; Mice; Mice, Inbred C57BL; Quercetin; Signal Transduction; STAT3 Transcription Factor | 2018 |
Plant flavonoid taxifolin inhibits the growth, migration and invasion of human osteosarcoma cells.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Flavonoids; G1 Phase Cell Cycle Checkpoints; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Osteosarcoma; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Quercetin; S-Phase Kinase-Associated Proteins; Signal Transduction; Transplantation, Heterologous | 2018 |
Research on Characteristics, Antioxidant and Antitumor Activities of Dihydroquercetin and Its Complexes.
Topics: Antineoplastic Agents; Antioxidants; Benzothiazoles; beta-Cyclodextrins; Biphenyl Compounds; Cell Survival; Hep G2 Cells; Humans; Lecithins; Picrates; Quercetin; Solubility; Structure-Activity Relationship; Sulfonic Acids | 2017 |
The mechanism of (+) taxifolin's protective antioxidant effect for •OH-treated bone marrow-derived mesenchymal stem cells.
Topics: Antioxidants; Bone Marrow Cells; Hydroxyl Radical; Inhibitory Concentration 50; Mesenchymal Stem Cells; Protective Agents; Quercetin; Spectrophotometry, Ultraviolet | 2017 |
[Protective effect of taxifolin on H2O2-induced
H9C2 cell pyroptosis].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; CARD Signaling Adaptor Proteins; Caspase 1; Cell Line; DNA-Binding Proteins; Hydrogen Peroxide; Interleukins; Membrane Potential, Mitochondrial; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Quercetin; Rats; Reactive Oxygen Species; Receptors, Cell Surface; RNA, Messenger | 2017 |
Taxifolin: Evaluation Through Ex vivo Permeations on Human Skin and Porcine Vaginal Mucosa.
Topics: Administration, Topical; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Emulsions; Female; Humans; In Vitro Techniques; Mucous Membrane; Permeability; Quercetin; Skin; Skin Absorption; Skin Cream; Swine; Vagina | 2018 |
Computational Study of the Aza-Michael Addition of the Flavonoid (+)-Taxifolin in the Inhibition of β-Amyloid Fibril Aggregation.
Topics: Amyloid; Amyloid beta-Peptides; Computational Biology; Flavonoids; Glutamine; Lysine; Quercetin; Stereoisomerism | 2018 |
Taxifolin suppresses rat and human testicular androgen biosynthetic enzymes.
Topics: 17-Hydroxysteroid Dehydrogenases; Androgens; Animals; Cells, Cultured; Humans; Leydig Cells; Male; Quercetin; Rats; Rats, Sprague-Dawley; Steroid 17-alpha-Hydroxylase; Testis | 2018 |
Kidney protection effects of dihydroquercetin on diabetic nephropathy through suppressing ROS and NLRP3 inflammasome.
Topics: Albuminuria; Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Fluoresceins; Inflammasomes; Kidney; Male; Mesangial Cells; NLR Family, Pyrin Domain-Containing 3 Protein; Quercetin; Rats, Sprague-Dawley; Reactive Oxygen Species; Streptozocin | 2018 |
Experimental Analysis of the Efficacy of Dihydroquercetin on the Model of Chronic Nonbacterial Inflammation of the Prostatic Gland.
Topics: Animals; Chronic Disease; Inflammation; Male; Prostate; Prostatitis; Quercetin; Rats; Rats, Wistar | 2018 |
Pretreatment with dihydroquercetin, a dietary flavonoid, protected against concanavalin A-induced immunological hepatic injury in mice and TNF-α/ActD-induced apoptosis in HepG2 cells.
Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Concanavalin A; Hep G2 Cells; Humans; Interleukin-10; Interleukin-2; Liver; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Quercetin; Tumor Necrosis Factor-alpha | 2018 |
Molecular Cloning and Functional Characterization of a Dihydroflavonol 4-Reductase from Vitis bellula.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Cloning, Molecular; Flavonoids; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Open Reading Frames; Plant Proteins; Proanthocyanidins; Quercetin; Vitis | 2018 |
Amelioration of Alcoholic Liver Steatosis by Dihydroquercetin through the Modulation of AMPK-Dependent Lipogenesis Mediated by P2X7R-NLRP3-Inflammasome Activation.
Topics: AMP-Activated Protein Kinases; Animals; Fatty Liver, Alcoholic; Humans; Inflammasomes; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Quercetin; Receptors, Purinergic P2X7 | 2018 |
Differential accumulation of silymarin induced by exposure of Silybum marianum L. callus cultures to several spectres of monochromatic lights.
Topics: Cells, Cultured; Light; Plant Leaves; Quercetin; Silybin; Silymarin | 2018 |
Druggability of the guanosine/adenosine/cytidine nucleoside hydrolase from Trichomonas vaginalis.
Topics: Adenosine; Enzyme Inhibitors; Inhibitory Concentration 50; N-Glycosyl Hydrolases; Protozoan Proteins; Quercetin; Ribavirin; Structure-Activity Relationship; Trichomonas vaginalis | 2018 |
Taxifolin binds with LXR (α & β) to attenuate DMBA-induced mammary carcinogenesis through mTOR/Maf-1/PTEN pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Liver X Receptors; MafB Transcription Factor; Mammary Neoplasms, Experimental; Molecular Docking Simulation; Oncogene Proteins; Protein Binding; PTEN Phosphohydrolase; Quercetin; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases | 2018 |
Dihydroquercetin and Fucoidin Inhibit the Increase of Angiotensin-Converting Enzyme Activity in the Rat Aorta after Irradiation.
Topics: Administration, Oral; Animals; Aorta; Dose-Response Relationship, Radiation; Endothelium, Vascular; Gene Expression; Injections, Intravenous; Male; Peptidyl-Dipeptidase A; Polysaccharides; Quercetin; Rats; Rats, Wistar; Whole-Body Irradiation; X-Rays | 2018 |
The Effect of Dihydroquercetin on Catalytic Activity of Iron (II) Ions in the Fenton Reaction.
Topics: Catalysis; Free Radical Scavengers; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Iron; Kinetics; Oxidation-Reduction; Quercetin; Solutions | 2018 |
Selected Phytoestrogens Distinguish Roles of ERα Transactivation and Ligand Binding for Anti-Inflammatory Activity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Atherosclerosis; Cell Line; Curcumin; Endothelial Cells; Estrogen Receptor alpha; Humans; Inflammation; Interleukin-1beta; Ligands; Lipopolysaccharides; Lipoproteins, LDL; MAP Kinase Kinase 4; Molecular Docking Simulation; Mutation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phytoestrogens; Protein Transport; Quercetin; Response Elements; Signal Transduction; Silymarin; Tumor Necrosis Factor-alpha | 2018 |
[Chemical Constituents from Glycosmis pentaphylla].
Topics: Arabinose; Drugs, Chinese Herbal; Flavonoids; Glycosides; Kaempferols; Quercetin; Rhamnose; Rutaceae | 2016 |
Flavonoids decrease the radiation-induced increase in the activity of the angiotensin-converting enzyme in rat aorta.
Topics: Animals; Aorta; Flavones; Flavonoids; Flavonols; Male; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar; Solubility | 2018 |
Taxifolin prevents postprandial hyperglycemia by regulating the activity of α-amylase: Evidence from an in vivo and in silico studies.
Topics: Acarbose; Alloxan; alpha-Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood Glucose; C-Reactive Protein; Catalytic Domain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glycoside Hydrolase Inhibitors; Lipase; Lipid Metabolism; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Quercetin; Rats | 2019 |
[The Flavonoids of Chemical Constituents of Osmanthus fragrans Roots].
Topics: Drugs, Chinese Herbal; Flavonoids; Oleaceae; Plant Roots; Quercetin | 2016 |
Laccase-Catalyzed Heterocoupling of Dihydroquercetin and p-Aminobenzoic Acid: Effect of the Reaction Product on Cultured Cells.
Topics: 4-Aminobenzoic Acid; Acetates; Biocatalysis; Cell Line, Tumor; Citric Acid; Humans; Laccase; Quercetin; Trametes | 2018 |
Localization of phenolic compounds in the fruits of Silybum marianum characterized by different silymarin chemotype and altered colour.
Topics: Color; Fruit; Genotype; Phenols; Phytochemicals; Proanthocyanidins; Quercetin; Seeds; Silybum marianum; Silymarin | 2018 |
Taxifolin, a natural flavonoid interacts with cell cycle regulators causes cell cycle arrest and causes tumor regression by activating Wnt/ β -catenin signaling pathway.
Topics: Apoptosis; Biomarkers; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Disease Progression; Flavonoids; Flow Cytometry; Gene Expression; Humans; Neoplasms; Quercetin; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2018 |
Blood Pressure Changes After Exposures Increasing Angiotensin-Converting Enzyme Activity and After Its Normalization with Dihydroquercetin in Male Wistar Rats.
Topics: Animals; Blood Pressure; Dexamethasone; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Quercetin; Radiation, Ionizing; Rats; Rats, Wistar | 2018 |
Experimental Study of the Effectiveness of Phenolic Antioxidants in Male Infertility Caused by Pathospermia.
Topics: Animals; Antioxidants; Infertility, Male; Male; Oligospermia; Oxidation-Reduction; Oxidative Stress; Phenols; Phenylethyl Alcohol; Quercetin; Rats; Rats, Wistar; Spermatozoa | 2018 |
Linear regression analysis of silychristin A, silybin A and silybin B contents in
Topics: Antioxidants; Biological Products; Biosynthetic Pathways; Flavonoids; Models, Theoretical; Quercetin; Regression Analysis; Silybin; Silybum marianum; Silymarin | 2020 |
Taxifolin Inhibits Receptor Activator of NF-κB Ligand-Induced Osteoclastogenesis of Human Bone Marrow-Derived Macrophages in vitro and Prevents Lipopolysaccharide-Induced Bone Loss in vivo.
Topics: Actins; Animals; Bone Resorption; Cathepsin K; Cell Differentiation; Disease Models, Animal; Humans; I-kappa B Kinase; Lipopolysaccharides; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Osteogenesis; Osteolysis; Quercetin; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Transcription Factor RelA | 2019 |
Cardioprotective effects of dihydroquercetin against ischemia reperfusion injury by inhibiting oxidative stress and endoplasmic reticulum stress-induced apoptosis via the PI3K/Akt pathway.
Topics: Animals; Apoptosis; Cardiotonic Agents; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Myocardial Reperfusion Injury; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quercetin; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Combining 26s rDNA and the Cre-loxP System for Iterative Gene Integration and Efficient Marker Curation in Yarrowia lipolytica.
Topics: Cytochrome P-450 Enzyme System; DNA Copy Number Variations; DNA, Ribosomal; Escherichia coli; Flavanones; Gene Dosage; Genetic Engineering; Genetic Vectors; Genomic Instability; Hydroxylation; Integrases; Metabolic Networks and Pathways; Multigene Family; Plasmids; Quercetin; Yarrowia | 2019 |
Taxifolin protects neurons against ischemic injury in vitro via the activation of antioxidant systems and signal transduction pathways of GABAergic neurons.
Topics: Animals; Antioxidants; Apoptosis; Calcium; Cell Hypoxia; Cells, Cultured; GABAergic Neurons; Glucose; Neuroprotective Agents; Oxidative Stress; Oxygen; Quercetin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Signal Transduction | 2019 |
[Analysis of dihydroquercetin physical modification via in vitro and in silico methods].
Topics: Computer Simulation; Larix; Models, Chemical; Quercetin | 2019 |
In vitro and in silico docking studies of antibacterial compounds derived from endophytic Penicillium setosum.
Topics: Anti-Bacterial Agents; beta-Galactosidase; Computer Simulation; Escherichia coli; Flavonoids; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Molecular Docking Simulation; Penicillium; Potassium; Quercetin; Secondary Metabolism; Sodium; Staphylococcus aureus | 2019 |
The Effect of Taxifolin on Cisplatin-Induced Pulmonary Damage in Rats: A Biochemical and Histopathological Evaluation.
Topics: Acute Lung Injury; Animals; Antioxidants; Cisplatin; DNA Damage; Glutathione; Malondialdehyde; Oxidative Stress; Quercetin; Rats; Rats, Wistar | 2019 |
Pleiotropic neuroprotective effects of taxifolin in cerebral amyloid angiopathy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cerebral Amyloid Angiopathy; Drug Evaluation, Preclinical; Endoplasmic Reticulum Stress; Lymphatic Vessels; Male; Mice; Microglia; Quercetin; Random Allocation | 2019 |
Effect of taxifolin on oxidative gastric injury induced by celiac artery ligation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celiac Artery; Disease Models, Animal; Gastric Mucosa; Ligation; Male; Oxidation-Reduction; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Reperfusion Injury | 2019 |
Cytoprotective effects of taxifolin against cadmium-induced apoptosis in human keratinocytes.
Topics: Apoptosis; Cadmium; Cell Line; Cell Survival; Cytoprotection; Humans; Keratinocytes; Quercetin; Reactive Oxygen Species | 2019 |
Dietary polyphenols rutin, taxifolin and quercetin related compounds target Leishmania amazonensis arginase.
Topics: Antiprotozoal Agents; Arginase; Humans; Kinetics; Leishmania; Leishmaniasis; Molecular Docking Simulation; Polyphenols; Protozoan Proteins; Quercetin; Rutin | 2019 |
Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Cell Line; Cell Survival; Chlorpyrifos; Cholinesterase Inhibitors; Cytokines; Mice; Microtubule-Associated Proteins; Neurotoxicity Syndromes; Oxidative Stress; Phagocytosis; Quercetin; Signal Transduction | 2019 |
Chitosan composite microparticles: A promising gastroadhesive system for taxifolin.
Topics: Adhesiveness; Animals; Chitosan; Drug Carriers; Drug Liberation; Excipients; Gastric Mucosa; Gastrointestinal Agents; Microtechnology; Mimusops; Particle Size; Permeability; Quercetin; Seeds; Silicon Dioxide; Swine | 2019 |
Taxifolin inhibits breast cancer cells proliferation, migration and invasion by promoting mesenchymal to epithelial transition via β-catenin signaling.
Topics: Animals; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Quercetin; Signal Transduction; Xenograft Model Antitumor Assays | 2019 |
Physical and Chemical Stability of Formulations Loaded with Taxifolin Tetra-octanoate.
Topics: Caprylates; Chromatography, High Pressure Liquid; Drug Compounding; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Structure; Monophenol Monooxygenase; Quercetin; Structure-Activity Relationship; Viscosity | 2019 |
Taxifolin alleviates apoptotic injury induced by DEHP exposure through cytochrome P450 homeostasis in chicken cardiomyocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cells, Cultured; Chickens; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Homeostasis; Myocytes, Cardiac; Oxidative Stress; Plasticizers; Quercetin | 2019 |
Effects of Catechin, Quercetin and Taxifolin on Redox Parameters and Metabolites Linked with Renal Health in Rotenone-toxified Rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catechin; Insecticides; Kidney; Kidney Diseases; Male; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Rotenone | 2019 |
Isolation, characterization and identification of antibiofouling metabolite from mangrove derived Streptomyces sampsonii PM33.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Biofouling; Embryo, Nonmammalian; Microbial Sensitivity Tests; Quercetin; Streptomyces; Zebrafish | 2019 |
In-depth investigation of the binding of flavonoid taxifolin with bovine hemoglobin at physiological pH: Spectroscopic and molecular docking studies.
Topics: Animals; Binding Sites; Cattle; Circular Dichroism; Fluorescence Polarization; Hemoglobins; Hydrogen-Ion Concentration; In Vitro Techniques; Molecular Docking Simulation; Protein Binding; Protein Conformation; Quercetin; Spectrometry, Fluorescence; Spectrum Analysis; Thermodynamics | 2020 |
Taxifolin ameliorates DEHP-induced cardiomyocyte hypertrophy via attenuating mitochondrial dysfunction and glycometabolism disorder in chicken.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Chickens; Diethylhexyl Phthalate; Mitochondria; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Quercetin; Ventricular Myosins | 2019 |
5,7,3',4'-flavan-on-ol (taxifolin) protects against acetaminophen-induced liver injury by regulating the glutathione pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Glutathione; Metabolome; Mice; Mice, Inbred C57BL; Oxidative Stress; Protective Agents; Quercetin; Reactive Oxygen Species | 2019 |
Effectiveness of Phenolic Antioxidants in Experimental Model of Benign Prostatic Hyperplasia.
Topics: Acinar Cells; Animals; Animals, Outbred Strains; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Humans; Male; Methimazole; Organ Size; Phenols; Prostate; Prostatic Hyperplasia; Quercetin; Rats; Sulpiride | 2019 |
Optimizing Oleaginous Yeast Cell Factories for Flavonoids and Hydroxylated Flavonoids Biosynthesis.
Topics: Acyltransferases; Bioreactors; Chorismic Acid; Flavanones; Gene Expression; Glucose; Hydrogen-Ion Concentration; Hydroxylation; Malonyl Coenzyme A; Metabolic Engineering; NADPH-Ferrihemoprotein Reductase; Quercetin; Sulfuric Acids; Synthetic Biology; Yarrowia | 2019 |
Taxifolin Shows Anticataractogenesis and Attenuates Diabetic Retinopathy in STZ-Diabetic Rats
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dose-Response Relationship, Drug; Male; MAP Kinase Signaling System; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Streptozocin | 2020 |
Hepatoprotective Mechanisms of Taxifolin on Carbon Tetrachloride-Induced Acute Liver Injury in Mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Quercetin | 2019 |
A Switch between Antioxidant and Prooxidant Properties of the Phenolic Compounds Myricetin, Morin, 3',4'-Dihydroxyflavone, Taxifolin and 4-Hydroxy-Coumarin in the Presence of Copper(II) Ions: A Spectroscopic, Absorption Titration and DNA Damage Study.
Topics: Antineoplastic Agents; Antioxidants; Chelating Agents; Copper; Coumarins; DNA Damage; Electron Spin Resonance Spectroscopy; Flavonoids; Humans; Hydroxyl Radical; Ions; Photoelectron Spectroscopy; Polyphenols; Quercetin; Reactive Oxygen Species | 2019 |
Taxifolin Inhibits Neurosteroidogenic Rat Steroid 5α-Reductase 1 and 3α-Hydroxysteroid Dehydrogenase.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aldehyde Reductase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chlorocebus aethiops; COS Cells; Membrane Proteins; Molecular Docking Simulation; Neurosteroids; Quercetin; Rats | 2020 |
In Vitro and in Vivo Anti-Hyperglycemic Activities of Taxifolin and Its Derivatives Isolated from Pigmented Rice (
Topics: Animals; Blood Glucose; Chromatography, High Pressure Liquid; Color; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Oryza; Plant Extracts; Postprandial Period; Quercetin; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2020 |
Taxifolin attenuates IMQ-induced murine psoriasis-like dermatitis by regulating T helper cell responses via Notch1 and JAK2/STAT3 signal pathways.
Topics: Animals; Cell Line; Cell Proliferation; Cyclosporine; Cytokines; Dermatitis; Humans; Imiquimod; Inflammation; Janus Kinase 2; Keratinocytes; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Models, Animal; Psoriasis; Quercetin; Receptor, Notch1; Signal Transduction; Skin; STAT3 Transcription Factor; T-Lymphocytes; Transcription Factors | 2020 |
Di-(2-ethyl hexyl) phthalate induces necroptosis in chicken cardiomyocytes by triggering calcium overload.
Topics: Animals; Avian Proteins; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chickens; Diethylhexyl Phthalate; Myocytes, Cardiac; Necroptosis; Protective Agents; Quercetin; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction | 2020 |
Metabolomics Reveals the Response of the Phenylpropanoid Biosynthesis Pathway to Starvation Treatment in the Grape Endophyte
Topics: Alternaria; Biosynthetic Pathways; Coumaric Acids; Endophytes; Fungal Proteins; Metabolomics; Phenols; Quercetin; Secondary Metabolism; Stilbenes; Vitis | 2020 |
7-O-Esters of taxifolin with pronounced and overadditive effects in neuroprotection, anti-neuroinflammation, and amelioration of short-term memory impairment in vivo.
Topics: Amyloid beta-Peptides; Animals; Esters; Memory, Short-Term; Mice; Microglia; Neuroprotection; Neuroprotective Agents; Quercetin | 2020 |
Ameliorative effect of quercetin, catechin, and taxifolin on rotenone-induced testicular and splenic weight gain and oxidative stress in rats.
Topics: Animals; Biomarkers; Catechin; Dose-Response Relationship, Drug; Inflammation Mediators; Male; Organ Size; Oxidative Stress; Protective Agents; Quercetin; Rats; Rotenone; Spleen; Testis; Weight Gain | 2020 |
In vitro and in vivo inhibitory activity of taxifolin on three digestive enzymes.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Enzyme Activation; Enzyme Inhibitors; Female; Glucose; Glycoside Hydrolase Inhibitors; Kinetics; Lipid Metabolism; Molecular Docking Simulation; Molecular Dynamics Simulation; Pancrelipase; Quercetin; Rats; Structure-Activity Relationship | 2020 |
Dihydroquercetin protects against renal fibrosis by activating the Nrf2 pathway.
Topics: Animals; Fibrosis; Hydrogen Peroxide; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protective Agents; Quercetin; Rats; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Ureteral Obstruction | 2020 |
Participation of Free-Radical Processes in Structural and Metabolic Disturbances in the Lung Tissues Caused by Exposure to Coal-Rock Dust and their Adaptogenic Correction.
Topics: Administration, Oral; Alanine Transaminase; Animals; Animals, Outbred Strains; Antioxidants; Aspartate Aminotransferases; Catalase; Coal; Drug Administration Schedule; Dust; Free Radicals; Gene Expression; Granuloma; Heme Oxygenase (Decyclizing); HSP72 Heat-Shock Proteins; Hydroxybutyrate Dehydrogenase; Hypoxia-Inducible Factor 1, alpha Subunit; Inhalation Exposure; Lung; Male; Oxidation-Reduction; Particle Size; Quercetin; Rats; Superoxide Dismutase | 2020 |
Magnetic molecularly imprinted specific solid-phase extraction for determination of dihydroquercetin from Larix griffithiana using HPLC.
Topics: Chromatography, High Pressure Liquid; Larix; Magnetic Phenomena; Molecular Imprinting; Quercetin; Solid Phase Extraction | 2020 |
Effects of Catechin on Activity of Angiotensin-Converting Enzyme and Generation of Reactive Oxygen Species in Rat Aorta.
Topics: Animals; Aorta; Catechin; Endothelium, Vascular; Male; Peptidyl-Dipeptidase A; Polysaccharides; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species | 2020 |
A study on the protective effects of taxifolin on human umbilical vein endothelial cells and THP-1 cells damaged by hexavalent chromium: a probable mechanism for preventing cardiovascular disease induced by heavy metals.
Topics: Cardiovascular Diseases; Chromium; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Kinase 4; Metals, Heavy; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Quercetin; THP-1 Cells | 2020 |
Influence of Natural Polyphenols on Isolated Yeast Dipodascus magnusii Mitochondria.
Topics: Antioxidants; Catechin; Flavonoids; Flavonols; Microbial Sensitivity Tests; Mitochondria; Oxygen Consumption; Polyphenols; Quercetin; Reactive Oxygen Species; Resveratrol; Saccharomycetales; Stilbenes | 2020 |
Taxifolin attenuates the developmental testicular toxicity induced by di-n-butyl phthalate in fetal male rats.
Topics: Animals; Antioxidants; Dibutyl Phthalate; Female; Male; Maternal Exposure; Plasticizers; Quercetin; Rats; Rats, Sprague-Dawley; Testis | 2020 |
The effects of taxifolin on alveolar bone in experimental periodontitis in rats.
Topics: Alveolar Bone Loss; Animals; Apoptosis; Osteocalcin; Periodontitis; Quercetin; RANK Ligand; Rats | 2020 |
Potential of MurA Enzyme and GBAP in Fsr Quorum Sensing System as Antibacterial Drugs Target: In vitro and In silico Study of Antibacterial Compounds from Myrmecodia pendans.
Topics: Alkyl and Aryl Transferases; Anti-Bacterial Agents; Bacterial Proteins; Biflavonoids; Drug Discovery; Enzyme Inhibitors; Gelatinases; Humans; In Vitro Techniques; Lactones; Molecular Docking Simulation; Peptides, Cyclic; Protein Binding; Quercetin; Quorum Sensing; Rubiaceae; Serine Proteases; Structure-Activity Relationship; Thermodynamics | 2021 |
Dihydroquercetin attenuates lipopolysaccharide-induced acute lung injury through modulating FOXO3-mediated NF-κB signaling via miR-132-3p.
Topics: Acute Lung Injury; Forkhead Box Protein O3; Humans; Lipopolysaccharides; MicroRNAs; NF-kappa B; Quercetin | 2020 |
Taxifolin ameliorates iron overload-induced hepatocellular injury: Modulating PI3K/AKT and p38 MAPK signaling, inflammatory response, and hepatocellular regeneration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chemical and Drug Induced Liver Injury; Inflammation; Iron; Iron Chelating Agents; Iron Overload; Liver Regeneration; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quercetin; Rats | 2020 |
Taxifolin tubes: crystal engineering and characteristics.
Topics: Crystallization; Crystallography, X-Ray; Hydrogen-Ion Concentration; Models, Molecular; Particle Size; Proton Magnetic Resonance Spectroscopy; Quercetin; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Surface Properties; Temperature | 2019 |
Decreasing glycerol content by co-supplementation of trehalose and taxifolin hydrate in ram semen extender: Microscopic, oxidative stress, and gene expression analyses.
Topics: Animals; Cryopreservation; Cryoprotective Agents; Dietary Supplements; Gene Expression; Glycerol; Humans; Male; Oxidative Stress; Quercetin; Semen; Semen Preservation; Sheep; Sperm Motility; Spermatozoa; Trehalose | 2020 |
Prospects for the use of regulators of oxidative stress in the comprehensive treatment of the novel Coronavirus Disease 2019 (COVID-19) and its complications.
Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Cytokines; Erythrocytes; Free Radical Scavengers; Hemoglobins; Humans; Oxidative Stress; Pandemics; Pneumonia, Viral; Pulmonary Alveoli; Quercetin; Reactive Oxygen Species; SARS-CoV-2; Uridine | 2020 |
Feeding dihydroquercetin and vitamin E to broiler chickens reared at standard and high ambient temperatures.
Topics: Animal Feed; Animals; Antioxidants; Chickens; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Gastrointestinal Tract; Jejunum; Male; Organ Size; Quercetin; Random Allocation; Temperature; Vitamin E; Vitamins | 2020 |
Effect of taxifolin on cisplatin-associated oxidative optic nerve damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cisplatin; Disease Models, Animal; Male; Optic Nerve; Optic Nerve Diseases; Oxidative Stress; Quercetin; Rats | 2021 |
Dibutyl phthalate-induced oxidative stress, inflammation and apoptosis in grass carp hepatocytes and the therapeutic use of taxifolin.
Topics: Animals; Apoptosis; Carps; Dibutyl Phthalate; Hepatocytes; Inflammation; Oxidative Stress; Quercetin | 2021 |
Antioxidant and antibacterial polyelectrolyte wound dressing based on chitosan/hyaluronan/phosphatidylcholine dihydroquercetin.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Bandages; Cells, Cultured; Chitosan; Erythrocytes; Female; Hemolysis; Humans; Hyaluronic Acid; Mice; NIH 3T3 Cells; Phosphatidylcholines; Quercetin; Rats; Rats, Wistar; Re-Epithelialization | 2021 |
Assembling the Puzzle of Taxifolin Polymorphism.
Topics: Chemistry, Pharmaceutical; Magnetic Resonance Spectroscopy; Molecular Structure; Particle Size; Quercetin; Spectrum Analysis; Structure-Activity Relationship; Thermogravimetry; X-Ray Diffraction | 2020 |
Computational guided identification of a citrus flavonoid as potential inhibitor of SARS-CoV-2 main protease.
Topics: Citrus; Coronavirus 3C Proteases; Drug Discovery; Flavonoids; Molecular Docking Simulation; Protease Inhibitors; Protein Conformation; Quercetin; SARS-CoV-2 | 2021 |
Protective effects of taxifolin on pazopanib-induced liver toxicity: an experimental rat model.
Topics: Animals; Chemical and Drug Induced Liver Injury; Indazoles; Liver; Male; Protective Agents; Pyrimidines; Quercetin; Rats; Rats, Wistar; Sulfonamides | 2021 |
Evaluation of the Protective Effect of Ademetionine, Cytoflavin, and Dihydroquercetetine on Blood Enzymes Activity in Rats Treated with High Doses of Sodium Valproate.
Topics: Alkaline Phosphatase; Animals; Anticonvulsants; Drug Combinations; Epilepsy; Erythrocytes; Flavin Mononucleotide; gamma-Glutamyltransferase; Inosine Diphosphate; Liver; Male; Niacinamide; Quercetin; Rats; S-Adenosylmethionine; Succinates; Time Factors; Valproic Acid | 2020 |
Taxifolin ameliorate high-fat-diet feeding plus acute ethanol binge-induced steatohepatitis through inhibiting inflammatory caspase-1-dependent pyroptosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binge Drinking; Cells, Cultured; Central Nervous System Depressants; Diet, High-Fat; Disease Models, Animal; Ethanol; Fatty Liver, Alcoholic; Humans; Male; Mice; Mice, Inbred ICR; Pyroptosis; Quercetin | 2021 |
[Identification of flavonoids 3-hydroxylase from [Silybum marianum (L.) Gaertn] and its application in enhanced production of taxifolin].
Topics: Antioxidants; Flavonoids; Quercetin; Silybum marianum | 2020 |
Epigenetic and Posttranscriptional Modulation of SOS1 Can Promote Breast Cancer Metastasis through Obesity-Activated c-Met Signaling in African-American Women.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biomarkers, Tumor; Black or African American; Breast Neoplasms; Cell Proliferation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; GRB2 Adaptor Protein; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Obesity; Prognosis; Proto-Oncogene Proteins c-met; Quercetin; SOS1 Protein; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |
Investigation of Phenolic Content in Five Different Pine Barks Species Grown in Turkey by HPLC-UV and LC-MS.
Topics: Catechin; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Phenols; Pinus; Plant Bark; Quercetin; Tandem Mass Spectrometry | 2021 |
Taxifolin, Extracted from Waste
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carbon Tetrachloride; Dose-Response Relationship, Drug; Hepatocytes; Inflammation; Larix; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Molecular Conformation; Oxidative Stress; Phosphatidylinositol 3-Kinases; Plant Roots; Proto-Oncogene Proteins c-akt; Quercetin; Signal Transduction; Smad Proteins; Structure-Activity Relationship; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1 | 2021 |
Comparative Study of Wound-Healing Activity of Dihydroquercetin Pseudopolymorphic Modifications.
Topics: Animals; Male; Polymorphism, Genetic; Quercetin; Rats; Rats, Sprague-Dawley; Regenerative Medicine; Wound Healing | 2021 |
The effect of taxifolin on oxidative ovarian damage and reproductive dysfunctions induced by antipsychotic drugs in female rats.
Topics: Animals; Antipsychotic Agents; Female; Oxidative Stress; Quercetin; Rats; Rats, Wistar | 2021 |
Phytochemicals from Ayurvedic plants as potential medicaments for ovarian cancer: an in silico analysis.
Topics: Antigens, Neoplasm; Cell Proliferation; Female; Furans; Hematoxylin; Humans; Lignans; Medicine, Ayurvedic; Molecular Docking Simulation; Ovarian Neoplasms; Phytochemicals; Quercetin | 2021 |
Dual Effect of Taxifolin on ZEB2 Cancer Signaling in HepG2 Cells.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expression; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocytes; Humans; MicroRNAs; Polyphenols; Primary Cell Culture; Quercetin; Signal Transduction; Transcriptome; Zinc Finger E-box Binding Homeobox 2 | 2021 |
Taxifolin ameliorates Benzo[a]pyrene-induced lung injury possibly via stimulating the Nrf2 signalling pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzopyrenes; Cigarette Smoking; Inflammation; Lipid Peroxidation; Lung; Lung Injury; Male; Mice; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Quercetin; Reactive Oxygen Species; Signal Transduction | 2021 |
Attenuation of diethyl nitrosamine-induced hepatocellular carcinoma by taxifolin and/or alogliptin: The interplay between toll-like receptor 4, transforming growth factor beta-1, and apoptosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Diethylnitrosamine; Gene Expression Regulation; Hypoglycemic Agents; Liver Neoplasms; Male; Piperidines; Quercetin; Random Allocation; Rats; Rats, Wistar; Toll-Like Receptor 4; Transforming Growth Factor beta1; Uracil | 2021 |
Effect of taxifolin/dapagliflozin combination on colistin-induced nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Beclin-1; Benzhydryl Compounds; Colistin; Drug Combinations; Gene Expression Regulation; Glucosides; Kidney Diseases; Male; MAP Kinase Kinase 4; Quercetin; Random Allocation; Rats; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Active Components from
Topics: Cassia; Catechin; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Oleanolic Acid; Palmitic Acid; Plant Extracts; Plant Roots; Quercetin; Stilbenes; Virus Internalization | 2021 |
Taxifolin, a novel food, attenuates acute alcohol-induced liver injury in mice through regulating the NF-κB-mediated inflammation and PI3K/Akt signalling pathways.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Dose-Response Relationship, Drug; Inflammation; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred ICR; NF-kappa B; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Quercetin; Signal Transduction | 2021 |
Taxifolin inhibits keratinocyte proliferation and ameliorates imiquimod-induced psoriasis-like mouse model via regulating cytoplasmic phospholipase A2 and PPAR-γ pathway.
Topics: Animals; Cell Line; Cell Proliferation; Cytoplasm; Disease Models, Animal; Down-Regulation; Humans; Imiquimod; Keratinocytes; Male; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phospholipases A2; Phosphorylation; PPAR gamma; Proteomics; Psoriasis; Quercetin; Signal Transduction | 2021 |
Protective effect of taxifolin against prooxidant and proinflammatory kidney damage associated with acrylamide in rats.
Topics: Acrylamide; Animals; Antioxidants; Glutathione; Inflammation; Interleukin-1beta; Kidney; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2021 |
Elucidation of myricetin biosynthesis in Morella rubra of the Myricaceae.
Topics: Cytochrome P-450 Enzyme System; Escherichia coli; Flavonoids; Flavonols; Gene Expression Regulation, Plant; Myricaceae; Nicotiana; Oxidoreductases; Plant Proteins; Plants, Genetically Modified; Quercetin; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity | 2021 |
Exploring the genes involved in biosynthesis of dihydroquercetin and dihydromyricetin in Ampelopsis grossedentata.
Topics: Ampelopsis; Biosynthetic Pathways; Cluster Analysis; Flavonoids; Flavonols; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Ontology; Genes, Plant; Molecular Sequence Annotation; Quercetin; RNA, Messenger; Transcriptome | 2021 |
The anti-obesity and gut microbiota modulating effects of taxifolin in C57BL/6J mice fed with a high-fat diet.
Topics: Animals; Diet, High-Fat; Gastrointestinal Microbiome; Mice; Mice, Inbred C57BL; Obesity; Quercetin; RNA, Ribosomal, 16S | 2022 |
The effect of taxifolin on high-dose-cisplatin-induced oxidative liver injury in rats.
Topics: Animals; Cisplatin; Liver; Male; Oxidative Stress; Quercetin; Rats; Rats, Wistar | 2021 |
Effects of taxifolin on bone formation and apoptosis in experimental periodontitis in diabetic rats.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Osteogenesis; Periodontitis; Quercetin; Rats | 2022 |
Antioxidant status and growth performance of broiler chickens fed diets containing graded levels of supplementary dihydroquercetin.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Chickens; Diet; Dietary Supplements; Quercetin | 2021 |
Effect of Taxifolin on Ischemia/Reperfusion-Induced Oxidative Injury of Sciatic Nerve in Rats.
Topics: Animals; Ischemia; Malondialdehyde; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Sciatic Nerve | 2021 |
Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice.
Topics: Aging; Animals; Galactose; Gastrointestinal Microbiome; Male; Memory Disorders; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Quercetin | 2021 |
Effect of the flavonoids quercetin and taxifolin on UVA-induced damage to human primary skin keratinocytes and fibroblasts.
Topics: Fibroblasts; Flavonoids; Humans; Keratinocytes; Oxidative Stress; Quercetin; Skin; Ultraviolet Rays | 2022 |
Exploring Dihydroflavonol-4-Reductase Reactivity and Selectivity by QM/MM-MD Simulations.
Topics: Alcohol Oxidoreductases; Biocatalysis; Flavonoids; Molecular Conformation; Molecular Dynamics Simulation; Quantum Theory; Quercetin; Substrate Specificity; Vitis | 2022 |
Dose- and time-dependent effects of taxifolin on viability and mineralization markers of osteoblast-like cells.
Topics: Alkaline Phosphatase; Cell Differentiation; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Osteoblasts; Quercetin; Time Factors | 2021 |
Dihydroquercetin suppresses cigarette smoke induced ferroptosis in the pathogenesis of chronic obstructive pulmonary disease by activating Nrf2-mediated pathway.
Topics: Animals; Ferroptosis; Mice; NF-E2-Related Factor 2; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quercetin; Smoke; Smoking | 2022 |
Taxifolin improves inflammatory injury of human bronchial epithelial cells by inhibiting matrix metalloproteinase (MMP) 10 via Wnt/β-catenin pathway.
Topics: Anti-Inflammatory Agents; Asthma; Bronchi; Cell Line; Cell Proliferation; Cell Survival; Down-Regulation; Epithelial Cells; Gene Expression Regulation; Humans; Matrix Metalloproteinase 10; Models, Biological; Quercetin; Tumor Necrosis Factor-alpha; Wnt Signaling Pathway | 2022 |
The effects of taxifolin on neuropathy related with hyperglycemia and neuropathic pain in rats: A biochemical and histopathological evaluation.
Topics: Alloxan; Animals; Antioxidants; Hyperglycemia; Male; Neuralgia; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Reactive Oxygen Species | 2022 |
Dihydroquercetin improves rotenone-induced Parkinsonism by regulating NF-κB-mediated inflammation pathway in rats.
Topics: Animals; Disease Models, Animal; Inflammation; Male; Neuroprotective Agents; NF-kappa B; Parkinsonian Disorders; Quercetin; Rats; Rats, Wistar; Rotenone | 2022 |
Fabrication of chitosan/PVP/dihydroquercetin nanocomposite film for in vitro and in vivo evaluation of wound healing.
Topics: Animals; Anti-Bacterial Agents; Chitosan; Escherichia coli; Nanocomposites; Nanofibers; Quercetin; Staphylococcus aureus; Vascular Endothelial Growth Factor A; Wound Healing | 2022 |
Taxifolin ameliorates sepsis-induced lung capillary leak through inhibiting the JAK/STAT3 pathway.
Topics: Animals; Disease Models, Animal; Humans; Lung; Mice; Quercetin; Sepsis; STAT3 Transcription Factor; Th17 Cells | 2022 |
Taxifolin Alleviates DSS-Induced Ulcerative Colitis by Acting on Gut Microbiome to Produce Butyric Acid.
Topics: Animals; Butyric Acid; Colitis, Ulcerative; Dextran Sulfate; Gastrointestinal Microbiome; Mice; Quercetin; RNA, Ribosomal, 16S | 2022 |
Ameliorative effect of taxifolin on gentamicin-induced ototoxicity via down-regulation of apoptotic pathways in mouse cochlear UB/OC-2 cells.
Topics: Animals; Apoptosis; Down-Regulation; Gentamicins; Mice; Ototoxicity; Quercetin; Reactive Oxygen Species | 2022 |
Hepatoprotective and neuroprotective effect of taxifolin on hepatic encephalopathy in rats.
Topics: Animals; Antioxidants; Hepatic Encephalopathy; Hyperammonemia; Liver; Neuroprotective Agents; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Thioacetamide | 2022 |
Effect of taxifolin and epigallocatechin-3-gallate on biomineralization potential of stem cells from dental apical papilla.
Topics: Alkaline Phosphatase; Biomineralization; Catechin; Cell Differentiation; Cells, Cultured; Dental Papilla; Quercetin; Stem Cells | 2022 |
Metabolism, tissue distribution and excretion of taxifolin in rat.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Quercetin; Rats; Tandem Mass Spectrometry; Tissue Distribution | 2022 |
Crystal Structure of an SSB Protein from
Topics: DNA-Binding Proteins; DNA, Single-Stranded; Protein Binding; Quercetin; Salmonella enterica; Salmonella typhimurium | 2022 |
A Three-Reagent "Green" Paper-Based Analytical Device for Solid-Phase Spectrometric and Colorimetric Determination of Dihydroquercetin.
Topics: Colorimetry; Ferric Compounds; Indicators and Reagents; Microfluidic Analytical Techniques; Paper; Quercetin | 2022 |
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Topics: Animals; Autophagy; Inflammation; Liposomes; Liver; Mice; Quercetin; Signal Transduction | 2022 |
Taxifolin blocks monosodium urate crystal-induced gouty inflammation by regulating phagocytosis and autophagy.
Topics: Arthritis, Gouty; Autophagy; Gout; Humans; Inflammation; Interleukin-1beta; Phagocytosis; Quercetin; Uric Acid | 2022 |
Modeling of the structure and forecasting properties of dihydroquercetin derivatives.
Topics: Models, Chemical; Quantum Theory; Quercetin; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics | 2022 |
Effect of Dihydroquercetin on Energy Metabolism in LPS-Induced Inflammatory Mice.
Topics: Animals; Energy Metabolism; Inflammation; Lipopolysaccharides; Liver; Mice; Nitrogen; Oxidative Stress; Quercetin | 2022 |
Taxifolin ameliorates lipopolysaccharide-induced intestinal epithelial barrier dysfunction via attenuating NF-kappa B/MLCK pathway in a Caco-2 cell monolayer model.
Topics: Caco-2 Cells; Humans; Intestinal Diseases; Intestinal Mucosa; Lipopolysaccharides; Myosin-Light-Chain Kinase; NF-kappa B; Quercetin; Tight Junction Proteins; Tumor Necrosis Factor-alpha | 2022 |
Effect of taxifolin on methotrexate-induced oxidative and inflammatory oral mucositis in rats: biochemical and histopathological evaluation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Glutathione; Interleukin-1beta; Interleukin-6; Malondialdehyde; Methotrexate; Oxidants; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Saline Solution; Solvents; Stomatitis; Tumor Necrosis Factor-alpha | 2022 |
The effect of taxifolin on oxidative sciatic nerve damage induced by cobalt chloride in rats: a biochemical and histopathological evaluation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cobalt; Glutathione; Malondialdehyde; Oxidants; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Sciatic Nerve; Superoxide Dismutase; Trace Elements | 2022 |
Engineering Saccharomyces cerevisiae for the production of dihydroquercetin from naringenin.
Topics: Flavanones; Flavonoids; NADPH-Ferrihemoprotein Reductase; Plant Proteins; Quercetin; Saccharomyces cerevisiae | 2022 |
Solubility Enhancement of Dihydroquercetin via "Green" Phase Modification.
Topics: Antioxidants; Calorimetry, Differential Scanning; Quercetin; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Water; X-Ray Diffraction | 2022 |
Effects of taxifolin on aspirin-induced gastric damage in rats: macroscopic and biochemical evaluation.
Topics: Animals; Antioxidants; Aspirin; Famotidine; Quercetin; Rats | 2023 |
Slow starch hydrolysis of non-glutinous rice flour and potato starch heated with taxifolin: contribution of proteins to the former and longer amylose to the latter.
Topics: Amylose; Flour; Hydrolysis; Oryza; Quercetin; Solanum tuberosum; Starch | 2023 |
A Comparative Analysis of Neuroprotective Properties of Taxifolin and Its Water-Soluble Form in Ischemia of Cerebral Cortical Cells of the Mouse.
Topics: Animals; Brain Ischemia; Cell Survival; Cells, Cultured; Glucose; Ischemia; Mice; Neurons; Neuroprotective Agents; Oxygen; Quercetin; Signal Transduction | 2023 |
Novel aspects of taxifolin pharmacokinetics: Dose proportionality, cumulative effect, metabolism, microemulsion dosage forms.
Topics: Administration, Oral; Animals; Chromatography, Liquid; Quercetin; Rats; Reproducibility of Results; Tandem Mass Spectrometry; Water | 2023 |
A Comparative Study of the Inhibitory Effect of Some Flavonoids and a Conjugate of Taxifolin with Glyoxylic Acid on the Oxidative Burst of Neutrophils.
Topics: Flavonoids; Humans; Neutrophils; Polyphenols; Quercetin; Reactive Oxygen Species; Respiratory Burst | 2023 |
Inhibitory effects of flavonoids on Moloney murine leukemia virus reverse transcriptase activity.
Topics: DNA Polymerase I; Flavonoids; Leukemia Virus, Murine; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 1992 |
Interactions of flavonoids and other phytochemicals with adenosine receptors.
Topics: Animals; Cell Line; CHO Cells; Cricetinae; Flavonoids; Humans; Magnetic Resonance Spectroscopy; Plants; Protein Binding; Radioligand Assay; Rats; Receptors, Purinergic P1 | 1996 |
Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers.
Topics: Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Structure-Activity Relationship; Xanthine Oxidase | 1998 |
Chemical constituents from Lippia sidoides and cytotoxic activity.
Topics: Aedes; Animals; Antineoplastic Agents, Phytogenic; Biomphalaria; Brazil; Drug Screening Assays, Antitumor; Insecticides; Magnetic Resonance Spectroscopy; Molluscacides; Naphthoquinones; Plants, Medicinal; Spectrophotometry, Infrared; Tumor Cells, Cultured | 2001 |
Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme.
Topics: ADP-ribosyl Cyclase 1; Animals; Binding Sites; Catalytic Domain; Computer Simulation; Enzyme Inhibitors; Flavonoids; High-Throughput Screening Assays; Humans; NAD+ Nucleosidase; Schistosoma mansoni; Schistosomicides; Structure-Activity Relationship | 2010 |
Flavonoids as inhibitors of human CD38.
Topics: ADP-ribosyl Cyclase 1; Anthocyanins; Catalytic Domain; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure | 2011 |
Synthesis, structure-activity relationship analysis and kinetics study of reductive derivatives of flavonoids as Helicobacter pylori urease inhibitors.
Topics: Bacterial Proteins; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Helicobacter pylori; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Structure; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Urease | 2013 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |