Compounds > taurolithocholic acid
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taurolithocholic acid and taurolithocholic acid 3-sulfate

taurolithocholic acid has been researched along with taurolithocholic acid 3-sulfate in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (19.15)18.2507
2000's14 (29.79)29.6817
2010's21 (44.68)24.3611
2020's3 (6.38)2.80

Authors

AuthorsStudies
Capiod, T; Claret, M; Combettes, L; Noel, J1
Dieminger, W; Dietrich, A; Gerok, W; Kurz, G; MacNelly, S1
Dieminger, W; Dietrich, A; Fuchte, K; Gerok, W; Kurz, G; Schlitz, E; Stoll, GH1
Cobbold, PH; Dixon, CJ; Marrero, I; Sanchez-Bueno, A1
Brink, MA; de Bruijn, MA; Groen, AK; Kuipers, F; Talsma, H; Verkade, HJ; Vonk, RJ1
Sano, N; Sato, A; Takikawa, H; Yamanaka, M1
Bremer, J; Cooper, MD; Dong, LJ; Herold, BC; Kirkpatrick, R; Krasa, H; Marcellino, D; Pilipenko, V; Travelstead, A1
Hanrahan, JW; Linsdell, P1
Abe, T; Ito, K; Sasaki, M; Sugiyama, Y; Suzuki, H1
Longbottom, R; Petersen, OH; Sutton, R; Tepikin, A; Voronina, S1
Fischer, R; Graf, D; Häussinger, D; Kurz, AK; Reinehr, R2
Fischer, R; Graf, D; Häussinger, D; Kircheis, G; Kurz, AK; Reinehr, R1
Sano, N; Takikawa, H; Tanaka, H1
Bolder, U; Hofmann, AF; Jauch, KW; Thasler, WE1
Häussinger, D; Reinehr, R1
Barrow, SL; Gerasimenko, OV; Petersen, OH; Tepikin, AV; Voronina, SG1
Hayashi, H; Hofmann, AF; Onuki, R; Sugiyama, Y; Suzuki, H; Takada, T1
Sano, N; Sasamoto, T; Takikawa, H1
Flowerdew, SE; Gerasimenko, JV; Gerasimenko, OV; Petersen, OH; Sukhomlin, TK; Tepikin, AV; Voronina, SG1
Fischer, L; Friess, H; Gukovskaya, AS; Gukovsky, I; Mareninova, OA; Pandol, SJ; Penninger, JM1
Becker, S; Eberle, A; Grether-Beck, S; Häussinger, D; Reinehr, R1
Donner, MM; Gorg, B; Graf, D; Haussinger, D; Mannack, G; Richter, L; Schliess, F; Vom Dahl, S1
Laukkarinen, JM; Perides, G; Steer, ML; Vassileva, G1
Barrow, SL; da Silva Xavier, G; Gerasimenko, OV; Petersen, OH; Rutter, GA; Simpson, AW; Tepikin, AV; Voronina, SG1
Laukkarinen, JM; Perides, G; Steer, ML; van Acker, GJ1
Buist-Homan, M; Conde de la Rosa, L; Faber, KN; Moshage, H; Woudenberg-Vrenken, TE1
Awais, M; Booth, DM; Criddle, DN; Gerasimenko, OV; Mukherjee, R; Murphy, JA; Neoptolemos, JP; Petersen, OH; Sutton, R; Tepikin, AV1
Barrat, F; Flavell, R; Gorelick, F; Hoque, R; Husain, S; Luo, Y; Malik, A; Mehal, W; Sarwar, S; Shah, A; Sohail, M1
Gukovskaya, AS; Gukovsky, I1
Ananthanaravanan, M; Bhandari, V; Choo-Wing, R; Husain, SZ; Luo, Y; Mahmood, SM; Muili, KA; Orabi, AI; Parness, J; Perides, G; Sarwar, S; Singh, VP; Wang, D1
Ananthanaravanan, M; Eisses, JF; Husain, SZ; Javed, TA; Jin, S; Luo, Y; Mahmood, SM; Molkentin, JD; Muili, KA; Orabi, AI; Perides, G; Sarwar, S; Singh, VP; Wang, D; Williams, JA1
Buist-Homan, M; Faber, KN; Henning, RH; Karimian, G; Mikus, B; Moshage, H1
Gao, B; Lu, M; Ma, B; Qiao, X; Sun, B; Wu, L; Xue, D; Zhang, W1
Bottino, R; Eisses, JF; Husain, SZ; Javed, TA; Jayaraman, T; Jin, S; Le, T; Muili, KA; Orabi, AI1
Bottino, R; Eisses, JF; Husain, SZ; Jayaraman, T; Jin, S; Lewarchik, CM; Malik, A; Muili, KA; Orabi, AI; Shah, AU; Wang, D1
Armstrong, J; Cash, N; Chvanov, M; Criddle, DN; Huang, W; Mukherjee, R; Murphy, MP; Sutton, R; Szatmary, P; Tepikin, AV; Wen, L1
Chen, YX; Fu, Q; Hu, MX; Liu, CJ; Qin, T; Tang, Q; Wang, YZ; Zhang, HW1
Ferdek, PE; Gerasimenko, JV; Gerasimenko, OV; Jakubowska, MA; Petersen, OH1
Banerjee, S; Barlass, U; Cheema, H; Dawra, R; Dixit, AK; Dudeja, V; George, J; Saluja, AK; Sareen, A; Sarver, AE; Subramanian, S; Yuan, Z1
Meng, S; Wang, H; Xue, D; Zhang, W1
Chung, SL; Date, K; Desir, GV; Gorelick, FS; Kolodecik, TR; Patel, V; Reed, AM; Shugrue, CA1
Awais, M; Bordet, T; Chvanov, M; Criddle, D; Huang, W; Javed, MA; Latawiec, D; Michaud, M; Pruss, R; Schaller, S; Sutton, R; Tepikin, A; Wen, L1
Ando, O; Kusuhara, H; Mori, D; Takehara, I; Watanabe, N1
Awais, M; Beckett, AJ; Chvanov, M; Criddle, DN; De Faveri, F; Haynes, L; Mayer, U; Moore, D; Pollock, L; Prior, IA; Sutton, R; Tepikin, AV; Voronina, S; Wileman, T1
Gao, B; Xue, D; Zhang, W; Zhang, X1
Liu, C; Qian, J; Wang, X; Weng, W; Zhou, G; Zhu, S1

Other Studies

47 other study(ies) available for taurolithocholic acid and taurolithocholic acid 3-sulfate

ArticleYear
Evidence for bile acid-evoked oscillations of Ca2(+)-dependent K+ permeability unrelated to a D-myo-inositol 1,4,5-trisphosphate effect in isolated guinea pig liver cells.
    The Journal of biological chemistry, 1991, Jan-05, Volume: 266, Issue:1

    Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Guinea Pigs; Heparin; Inositol 1,4,5-Trisphosphate; Ionomycin; Kinetics; Liver; Male; Norepinephrine; Potassium; Potassium Channels; Saponins; Taurolithocholic Acid; Time Factors

1991
Synthesis and applicability of a photolabile 7,7-azi analogue of 3-sulfated taurine-conjugated bile salts.
    Journal of lipid research, 1995, Volume: 36, Issue:8

    Topics: Affinity Labels; Animals; Azo Compounds; Binding, Competitive; Biological Transport; Liver; Male; Photolysis; Rats; Rats, Wistar; Taurocholic Acid; Taurolithocholic Acid

1995
Functional significance of interaction of H-FABP with sulfated and nonsulfated taurine-conjugated bile salts in rat liver.
    Journal of lipid research, 1995, Volume: 36, Issue:8

    Topics: Affinity Labels; Animals; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cytosol; Electrophoresis, Polyacrylamide Gel; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Isoelectric Focusing; Liver; Male; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Precipitin Tests; Rats; Rats, Wistar; Solubility; Subcellular Fractions; Sulfuric Acid Esters; Taurine; Taurolithocholic Acid

1995
Taurolithocholate and taurolithocholate 3-sulphate exert different effects on cytosolic free Ca2+ concentration in rat hepatocytes.
    The Biochemical journal, 1994, Jun-01, Volume: 300 ( Pt 2)

    Topics: Adenosine Triphosphate; Animals; Calcium; Chromatography, Thin Layer; Cytosol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Liver; Male; Rats; Rats, Wistar; Ryanodine; Taurolithocholic Acid

1994
Interactions between organic anions, micelles and vesicles in model bile systems.
    The Biochemical journal, 1996, Dec-15, Volume: 320 ( Pt 3)

    Topics: Ampicillin; Anions; Bile; Bile Acids and Salts; Cholesterol; Fluoresceins; Indocyanine Green; Liposomes; Micelles; Models, Biological; Particle Size; Scattering, Radiation; Taurodeoxycholic Acid; Taurolithocholic Acid; Ultracentrifugation

1996
Effect of taurolithocholate-3-sulphate on biliary excretion of sulphobromophthalein and dibromosulphophthalein in the Eisai hyperbilirubinaemic rat.
    Journal of gastroenterology and hepatology, 1997, Volume: 12, Issue:7

    Topics: Animals; Bile; Chromatography, Thin Layer; Hyperbilirubinemia; Male; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Taurolithocholic Acid; Time Factors

1997
Bile salts: natural detergents for the prevention of sexually transmitted diseases.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:4

    Topics: Bile Acids and Salts; Cell Division; Chlamydia Infections; Chlamydia trachomatis; Detergents; Drug Synergism; Gastrointestinal Agents; Glycocholic Acid; Gonorrhea; HeLa Cells; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Sexually Transmitted Diseases; Taurolithocholic Acid

1999
Substrates of multidrug resistance-associated proteins block the cystic fibrosis transmembrane conductance regulator chloride channel.
    British journal of pharmacology, 1999, Volume: 126, Issue:6

    Topics: Animals; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Chlorides; CHO Cells; Cholates; Cricetinae; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Electric Stimulation; Estradiol; Glyburide; Membrane Potentials; Multidrug Resistance-Associated Proteins; ortho-Aminobenzoates; Stilbenes; Taurocholic Acid; Taurolithocholic Acid

1999
Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2).
    The Journal of biological chemistry, 2002, Feb-22, Volume: 277, Issue:8

    Topics: Animals; Biological Transport; Cell Culture Techniques; Cell Line; Cell Membrane; Dehydroepiandrosterone Sulfate; Dogs; Estradiol; Estrone; Humans; Kidney; Kinetics; Liver-Specific Organic Anion Transporter 1; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rats; Recombinant Proteins; Taurolithocholic Acid; Transfection

2002
Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology.
    The Journal of physiology, 2002, Apr-01, Volume: 540, Issue:Pt 1

    Topics: Acetylcholine; Acute Disease; Animals; Bile Acids and Salts; Calcium; Calcium Signaling; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Pancreas; Pancreatitis; Taurolithocholic Acid

2002
Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner.
    Gastroenterology, 2002, Volume: 122, Issue:5

    Topics: Animals; Apoptosis; Caspase 8; Caspase 9; Caspases; Cells, Cultured; fas Receptor; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Taurodeoxycholic Acid; Taurolithocholic Acid

2002
Prevention of bile acid-induced apoptosis by betaine in rat liver.
    Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:4 Pt 1

    Topics: Animals; Apoptosis; Betaine; Bile Acids and Salts; Cell Membrane; Cells, Cultured; Cholestasis; fas Receptor; Glycochenodeoxycholic Acid; Hepatocytes; In Vitro Techniques; Ligation; Lipotropic Agents; Liver Diseases; Male; Oxidative Stress; Rats; Rats, Wistar; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; Taurolithocholic Acid

2002
Inhibition of taurolithocholate 3-sulfate-induced apoptosis by cyclic AMP in rat hepatocytes involves protein kinase A-dependent and -independent mechanisms.
    Archives of biochemistry and biophysics, 2003, Jul-01, Volume: 415, Issue:1

    Topics: Animals; Apoptosis; Bile Acids and Salts; Caspase 3; Caspase 8; Caspase 9; Caspases; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; fas Receptor; Hepatocytes; Male; Mitogen-Activated Protein Kinase Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Taurolithocholic Acid

2003
Biliary excretion of phenolphthalein sulfate in rats.
    Pharmacology, 2003, Volume: 68, Issue:4

    Topics: Animals; Anions; ATP-Binding Cassette Transporters; Bile; Carrier Proteins; Leukotriene C4; Male; Phenolphthalein; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Sulfobromophthalein; Taurolithocholic Acid; Time Factors

2003
[Hepatocellular transport of bile acids and organic anions in infection and SIRS--evidence for different mechanisms for regulating membrane transport proteins].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1998, Volume: 115, Issue:Suppl I

    Topics: Animals; Antiporters; Bile Acids and Salts; Biological Transport; Cell Membrane Permeability; Hepatocytes; Lipopolysaccharides; Organic Anion Transporters; Rats; Shock, Septic; Systemic Inflammatory Response Syndrome; Taurolithocholic Acid

1998
Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95.
    Gastroenterology, 2004, Volume: 126, Issue:1

    Topics: Adenosine; Animals; Apoptosis; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; ErbB Receptors; fas Receptor; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Serine; Taurolithocholic Acid; Threonine

2004
Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells: comparison of different modes of evaluating DeltaPsim.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Animals; Bile Acids and Salts; Bombesin; Bucladesine; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cholecystokinin; Enzyme Inhibitors; Intracellular Membranes; Membrane Potentials; Mice; Mitochondria; Pancreas; Rhodamines; Sincalide; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid; Thapsigargin; Uncoupling Agents

2004
Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate: a comparison of human BSEP with rat Bsep.
    Biochimica et biophysica acta, 2005, Dec-30, Volume: 1738, Issue:1-3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Cell Membrane; Cells, Cultured; Glycine; Humans; Kinetics; Multidrug Resistance-Associated Protein 2; Rats; Species Specificity; Taurine; Taurocholic Acid; Taurolithocholic Acid; Transport Vesicles

2005
Biliary excretion of sulfated bile acids and organic anions in zone 1- and zone 3-injured rats.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:1 Pt 1

    Topics: Animals; Anions; ATP-Binding Cassette Transporters; Bile; Bile Acids and Salts; Biliary Tract; Biological Transport; Bromobenzenes; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Male; Phenolphthaleins; Pravastatin; Propanols; Rats; Rats, Sprague-Dawley; Taurolithocholic Acid

2006
Bile acids induce Ca2+ release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors.
    The Journal of biological chemistry, 2006, Dec-29, Volume: 281, Issue:52

    Topics: Animals; Caffeine; Calcium; Endoplasmic Reticulum; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Male; Mice; NADP; Pancreas, Exocrine; Ryanodine Receptor Calcium Release Channel; Secretory Vesicles; Signal Transduction; Taurolithocholic Acid

2006
Phosphatidylinositol 3-kinase facilitates bile acid-induced Ca(2+) responses in pancreatic acinar cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:3

    Topics: Androstadienes; Animals; Bile Acids and Salts; Calcium; Cells, Cultured; Cholecystokinin; Chromones; Enzyme Activation; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate Receptors; Ionomycin; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Pancreas, Exocrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Taurochenodeoxycholic Acid; Taurolithocholic Acid; Thapsigargin; Wortmannin

2007
Hydrophobic bile salts trigger ceramide formation through endosomal acidification.
    Biological chemistry, 2007, Volume: 388, Issue:2

    Topics: Animals; Apoptosis; Cells, Cultured; Ceramides; Chlorides; Endosomes; Fluorescence; Hepatocytes; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Male; NADPH Oxidases; Phosphorylation; Rats; Rats, Wistar; Serine; Sphingomyelin Phosphodiesterase; Structure-Activity Relationship; Taurolithocholic Acid; Time Factors

2007
Taurolithocholic acid-3 sulfate impairs insulin signaling in cultured rat hepatocytes and perfused rat liver.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2008, Volume: 21, Issue:1-3

    Topics: Animals; Bile Acids and Salts; Bile Ducts; Cells, Cultured; Enzyme Activation; Hepatocytes; Insulin; Ligation; Liver; Liver Neoplasms, Experimental; Male; Perfusion; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Insulin; Signal Transduction; Taurochenodeoxycholic Acid; Taurolithocholic Acid

2008
Biliary acute pancreatitis in mice is mediated by the G-protein-coupled cell surface bile acid receptor Gpbar1.
    Gastroenterology, 2010, Volume: 138, Issue:2

    Topics: Acute Disease; Amylases; Animals; Bile Acids and Salts; Calcium Signaling; Ceruletide; Disease Models, Animal; Enzyme Precursors; GTP-Binding Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreas; Pancreatitis; Receptors, G-Protein-Coupled; Severity of Illness Index; Taurolithocholic Acid

2010
Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells.
    Gastroenterology, 2010, Volume: 138, Issue:5

    Topics: Adenosine Triphosphate; Animals; Antimetabolites; Calcium; Cells, Cultured; Cholecystokinin; Cytosol; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Glycolysis; Ionophores; Kinetics; Luciferases; Male; Mice; Mitochondria; Oxidative Phosphorylation; Pancreas, Exocrine; Taurolithocholic Acid; Transfection

2010
Experimental acute biliary pancreatitis induced by retrograde infusion of bile acids into the mouse pancreatic duct.
    Nature protocols, 2010, Volume: 5, Issue:2

    Topics: Animals; Bile Acids and Salts; Disease Models, Animal; Infusions, Parenteral; Mice; Pancreatic Ducts; Pancreatitis; Reference Values; Taurocholic Acid; Taurolithocholic Acid

2010
Anti-oxidants do not prevent bile acid-induced cell death in rat hepatocytes.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:10

    Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cells, Cultured; Cytoprotection; Glycochenodeoxycholic Acid; Heme Oxygenase (Decyclizing); Hepatocytes; Male; NADPH Oxidases; Necrosis; Oxidative Stress; Protein Kinase Inhibitors; Rats; Rats, Wistar; Rats, Zucker; Reactive Oxygen Species; RNA, Messenger; src-Family Kinases; Taurolithocholic Acid

2010
Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells.
    Gastroenterology, 2011, Volume: 140, Issue:7

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Calcium; Chlorides; Cytoprotection; Humans; Membrane Potentials; Mice; Microscopy, Confocal; Mitochondria; NADP; Necrosis; Oxidants; Oxidative Stress; Pancreas, Exocrine; Pancreatitis; Patch-Clamp Techniques; Reactive Oxygen Species; Signal Transduction; Taurolithocholic Acid; Time Factors

2011
TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis.
    Gastroenterology, 2011, Volume: 141, Issue:1

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Ceruletide; Cytoskeletal Proteins; Disease Models, Animal; DNA; Inflammasomes; Interleukin-1; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neutrophil Infiltration; NLR Family, Pyrin Domain-Containing 3 Protein; Pancreas; Pancreatitis; Pneumonia; Protein Precursors; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; RNA, Messenger; Severity of Illness Index; Signal Transduction; Taurolithocholic Acid; Toll-Like Receptor 9

2011
Which way to die: the regulation of acinar cell death in pancreatitis by mitochondria, calcium, and reactive oxygen species.
    Gastroenterology, 2011, Volume: 140, Issue:7

    Topics: Animals; Antioxidants; Apoptosis; Calcium; Cytoprotection; Humans; Membrane Potentials; Mitochondria; Necrosis; Oxidants; Oxidative Stress; Pancreas, Exocrine; Pancreatitis; Reactive Oxygen Species; Signal Transduction; Taurolithocholic Acid

2011
Ryanodine receptors contribute to bile acid-induced pathological calcium signaling and pancreatitis in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Jun-15, Volume: 302, Issue:12

    Topics: Acinar Cells; Animals; Bile Acids and Salts; Calcium Signaling; Dantrolene; Male; Mice; Pancreatitis; Ryanodine; Ryanodine Receptor Calcium Release Channel; Taurolithocholic Acid

2012
Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.
    The Journal of biological chemistry, 2013, Jan-04, Volume: 288, Issue:1

    Topics: Acinar Cells; Animals; Bile Acids and Salts; Calcineurin; Calcium; Chymotrypsin; Cytosol; Egtazic Acid; L-Lactate Dehydrogenase; Mice; NF-kappa B; NFATC Transcription Factors; Pancreas; Pancreatitis; Protein Isoforms; Tacrolimus; Taurolithocholic Acid; Time Factors

2013
Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Angiotensin II; Animals; Apoptosis; Caspase 3; Cell Shape; Cells, Cultured; Dactinomycin; Endoplasmic Reticulum Stress; Enzyme Activation; Glycochenodeoxycholic Acid; Hepatocytes; Male; MAP Kinase Signaling System; Oxidative Stress; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Protein Kinase C; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Taurolithocholic Acid; Tumor Necrosis Factor-alpha; Vitamin K 3

2012
Differentially expressed kinase genes associated with trypsinogen activation in rat pancreatic acinar cells treated with taurolithocholic acid 3-sulfate.
    Molecular medicine reports, 2013, Volume: 7, Issue:5

    Topics: Acinar Cells; Animals; Cell Line; Enzyme Activation; Gene Expression Profiling; Gene Regulatory Networks; Pancreas; Protein Kinases; Rats; Signal Transduction; Taurolithocholic Acid; Trypsinogen

2013
Pancreatic acinar cell nuclear factor κB activation because of bile acid exposure is dependent on calcineurin.
    The Journal of biological chemistry, 2013, Jul-19, Volume: 288, Issue:29

    Topics: Acinar Cells; Animals; Bile Acids and Salts; Calcineurin; Humans; Lipopolysaccharides; Male; Mice; Models, Biological; NF-kappa B; Pancreas; Protein Kinase C-delta; Protein Transport; Rats; Taurolithocholic Acid

2013
The ryanodine receptor is expressed in human pancreatic acinar cells and contributes to acinar cell injury.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Sep-01, Volume: 307, Issue:5

    Topics: Acinar Cells; Animals; Calcium; Carbachol; Cell Death; Humans; L-Lactate Dehydrogenase; Mice; Pancreas; Protein Isoforms; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; Taurolithocholic Acid

2014
Effects of the mitochondria-targeted antioxidant mitoquinone in murine acute pancreatitis.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Acinar Cells; Acute Disease; Animals; Antioxidants; Apoptosis; Ceruletide; Cholecystokinin; Disease Models, Animal; Inflammation; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Necrosis; Organophosphorus Compounds; Oxidative Stress; Pancreas; Pancreatitis; Reactive Oxygen Species; Taurolithocholic Acid; Ubiquinone

2015
Functional role of MicroRNA-19b in acinar cell necrosis in acute necrotizing pancreatitis.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2016, Volume: 36, Issue:2

    Topics: Acinar Cells; Animals; Arginine; Cell Line; MicroRNAs; Necrosis; Pancreatitis, Acute Necrotizing; Rats; Rats, Sprague-Dawley; Taurolithocholic Acid; Up-Regulation

2016
Bile acids induce necrosis in pancreatic stellate cells dependent on calcium entry and sodium-driven bile uptake.
    The Journal of physiology, 2016, 11-01, Volume: 594, Issue:21

    Topics: Acinar Cells; Animals; Bile; Bradykinin; Calcium Signaling; Cells, Cultured; Humans; Male; Mice; Mice, Inbred C57BL; Pancreatic Stellate Cells; Pancreatitis, Acute Necrotizing; Sodium; Taurolithocholic Acid

2016
Comprehensive analysis of microRNA signature of mouse pancreatic acini: overexpression of miR-21-3p in acute pancreatitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2016, 11-01, Volume: 311, Issue:5

    Topics: Acinar Cells; Animals; Ceruletide; Gene Expression; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Mice; MicroRNAs; Pancreatitis; Taurolithocholic Acid

2016
Screening and validation of differentially expressed extracellular miRNAs in acute pancreatitis.
    Molecular medicine reports, 2017, Volume: 16, Issue:5

    Topics: Acinar Cells; Acute Disease; Adult; Aged; Animals; Cell Line; Computational Biology; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Humans; Male; Microarray Analysis; MicroRNAs; Middle Aged; Molecular Sequence Annotation; Pancreas; Pancreatitis; Rats; Severity of Illness Index; Signal Transduction; Taurolithocholic Acid

2017
The serum protein renalase reduces injury in experimental pancreatitis.
    The Journal of biological chemistry, 2017, 12-22, Volume: 292, Issue:51

    Topics: Acinar Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Calcium Signaling; Carbachol; Cell Line; Ceruletide; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Ligands; Membrane Transport Modulators; Mice; Mice, Knockout; Monoamine Oxidase; Pancreas; Pancreatitis; Plasma Membrane Calcium-Transporting ATPases; Recombinant Fusion Proteins; Taurolithocholic Acid

2017
TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester-Induced Mitochondrial Injury and Necrotic Cell Death.
    Pancreas, 2018, Volume: 47, Issue:1

    Topics: Acinar Cells; Acute Disease; Animals; Ceruletide; Esters; Fatty Acids; Humans; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria; Necrosis; Oximes; Pancreatitis; Pancreatitis, Alcoholic; Secosteroids; Taurolithocholic Acid

2018
Effect of Rifampicin on the Plasma Concentrations of Bile Acid-O-Sulfates in Monkeys and Human Liver-Transplanted Chimeric Mice With or Without Bile Flow Diversion.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:8

    Topics: Animals; Glycocholic Acid; Humans; Lithocholic Acid; Liver; Liver Transplantation; Liver-Specific Organic Anion Transporter 1; Macaca fascicularis; Male; Mice; Rifampin; Taurolithocholic Acid

2019
LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells.
    Autophagy, 2020, Volume: 16, Issue:7

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acinar Cells; Actins; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Autophagy-Related Proteins; Chloroquine; Cholecystokinin; Endocytosis; Mice, Inbred C57BL; Microtubule-Associated Proteins; Onium Compounds; Pancreas; Phagocytosis; Phosphatidylinositol 3-Kinases; Protein Domains; Protein Kinase Inhibitors; Reactive Oxygen Species; Resveratrol; Taurolithocholic Acid; Trypsinogen; Vacuolar Proton-Translocating ATPases; Vacuoles

2020
Effects of Egr1 on pancreatic acinar intracellular trypsinogen activation and the associated ceRNA network.
    Molecular medicine reports, 2020, Volume: 22, Issue:3

    Topics: Animals; Cell Line; Computational Biology; Early Growth Response Protein 1; Enzyme Activation; Gene Expression Profiling; Gene Regulatory Networks; MicroRNAs; Models, Biological; Oligonucleotide Array Sequence Analysis; Pancreatitis; Rats; RNA, Long Noncoding; RNA, Small Interfering; Taurolithocholic Acid; Trypsinogen; Up-Regulation

2020
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142

    Topics: Animals; Autophagy; Cell Line; Cell Survival; Glucosides; Inflammation; NF-kappa B; Pancreas; Pancreatitis; Phenols; Rats; Signal Transduction; Taurolithocholic Acid

2021