Page last updated: 2024-08-17

taurocholic acid and ursodeoxycholic acid

taurocholic acid has been researched along with ursodeoxycholic acid in 80 studies

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-199023 (28.75)18.7374
1990's32 (40.00)18.2507
2000's10 (12.50)29.6817
2010's14 (17.50)24.3611
2020's1 (1.25)2.80

Authors

AuthorsStudies
Hagenbuch, B; Hofmann, AF; Kullak-Ublick, GA; Meier, PJ; Schteingart, CD; Stieger, B; Wolkoff, AW1
Arias, IM; Fantappié, O; Gatmaitan, Z; Gentilini, P; Kamimoto, Y; Mazzanti, R1
Hagenbuch, B; Kullak-Ublick, GA; Meier, PJ; Stieger, B; Wolkoff, AW1
Hagenbuch, B; Meier, PJ1
Ananthanarayanan, M; Boyer, JL; Hagenbuch, B; Hofmann, AF; Meier, PJ; Ng, OC; Schteingart, CD; Stieger, B1
Cainelli, G; Cerrè, C; Manetta, AC; Panunzio, M; Roda, A; Umani-Ronchi, A1
Craddock, AL; Daniel, RW; Dawson, PA; Kirby, LC; Love, MW; Walters, HC; Wong, MH1
Hashimoto, Y; Ibaramoto, K; Inui, KI; Masuda, S; Saito, H; Takeuchi, A1
Cvetkovic, M; Kim, RB; Leake, B; Nadeau, J; Roden, MM; Walubo, A; Wilkinson, GR1
Green, RM; Hoda, F; Ward, KL1
Denk, H; Fickert, P; Fuchsbichler, A; Lammert, F; Meier, PJ; Pojer, C; Stieger, B; Stumptner, C; Trauner, M; Zatloukal, K; Zenz, R; Zollner, G1
Ananthanarayanan, M; Batta, A; Eftychiou, N; Hata, S; Pang, KS; Salen, G; Wang, P; Wolkoff, AW1
Hummel-Eisenbeiss, J; Jedlitschky, G; Keppler, D; Nies, AT; Rius, M1
Akita, H; Hofmann, AF; Meier, PJ; Mita, S; Stieger, B; Sugiyama, Y; Suzuki, H1
Auwerx, J; Gioiello, A; Hofmann, AF; Macchiarulo, A; Pellicciari, R; Saladin, R; Sato, H; Schoonjans, K; Thomas, C; Une, M1
Gilmer, JF; Keaveney, R; Kelleher, D; Long, A; Majer, F; Peta, VK; Sharma, R; Wang, J1
Gerolami, A; Montet, AM; Montet, JC; Reynier, MO1
Hayakawa, T; Hoshino, M; Katagiri, K; Nakai, T; Ohiwa, T1
Fukui, H; Ishizaka, S; Kubo, R; Matsumura, K; Matsumura, Y; Tsujii, T; Yamao, J; Yoshikawa, M1
Ballet, F; Bonnefis, MT; Chazouillères, O; Chrétien, Y; Legendre, C; Poupon, R; Rey, C1
Angelin, B; Cederlund, T; Einarsson, K; Ericsson, S; Eusufzai, S1
Kanai, S; Kitani, K; Sato, Y1
Garcia-Marin, JJ; Perez-Antona, JC; Perez-Barriocanal, F; Regueiro, P; Villanueva, GR1
Chazouilléres, O; Jian, R; Marteau, P; Myara, A; Poupon, R; Rambaud, JC1
Niu, N; Smith, BF1
Berenson, MM; Bjorkman, DJ; Gunther, C; Samowitz, WS1
Corbic, M; Dumont, M; Erlinger, S; Farges, O; Maurice, M1
Matsumura, M; Saito, S1
Egestad, B; Marschall, HU; Matern, H; Matern, S; Sjövall, J1
Boyer, JL; Gautam, A; Ng, OC; Strazzabosco, M1
Nokubo, M1
Buanes, T; Grotmol, T; Landsverk, T; Raeder, MG; Ridderstråle, Y; Veel, T1
Bailey, ME; Pain, JA1
Gérolami, A; Marteau, C; Mathieu, S; Pauli, AM; Portugal, H1
Berenson, MM; Garcia-Marin, JJ; Perez-Barriocanal, F; Redondo-Torres, JG1
Buanes, T; Grotmol, T; Raeder, MG1
Goebell, H; Gries, E; Hotz, J1
Highsmith, WE; Hyde, PM1
Lake, JR; Scharschmidt, BF; Van Dyke, RW1
Gurantz, D; Hagey, LR; Hofmann, AF; Michelotti, EL; Steinbach, JH; Yoon, YB1
Koopman, BJ; van der Molen, JC; Waterreus, RJ; Wolthers, BG1
Hollander, D; Said, HM; Strum, WB1
Kanai, S; Kitani, K2
Dumont, M; Erlinger, S; Zouboulis-Vafiadis, I1
Batta, AK; Salen, G; Shefer, S1
Dumont, M; Erlinger, S; Uchman, S1
Czygan, P; Götz, R; Kommerell, B; Männer, C; Raedsch, R; Stiehl, A; Walker, S1
Gondo, K; Harada, M; Sakisaka, S; Tanikawa, K; Yoshitake, M1
Galan, AI; Tiribelli, C; Torres, AM1
Alonso, JR; Badia, MD; el-Mir, MY; Marin, JJ; Monte, MJ; Palomero, F1
Bassotti, C; Benedetti, A; Contucci, S; Jezequel, AM; Mancini, R; Marucci, L; Orlandi, F1
Friman, S; Nilsson, B; Svanvik, J; Thune, A1
Aldini, R; Biagi, PL; Hrelia, S; Montagnani, M; Roda, A; Roda, E1
Grune, S; Jameson, HL; Myers, NC; Sawkat-Anwer, M1
Bernard, B; Bouvier, E; Cabrol, A; Cadranel, JF; Dorent, R; Gandjbakhch, I; Gerhardt, M; Ghoussoub, JJ; Lunel, F; Myara, A; Opolon, P; Trivin, F1
Chazouillères, O; Haniche, M; Jian, R; Marteau, P; Poupon, R1
Ellul, JP; Gilani, SS; Murphy, GM1
Abroon, J; Batta, AK; Salen, G1
Bouscarel, B; Ceryak, S; Fromm, H; Gettys, TW; Le, M; Matsuzaki, Y; Shoda, J1
Cheng, Y; Duan, RD; Nilsson, A; Tauschel, HD1
Gores, GJ; LaRusso, NF; Phan, VA; Phan, VH; Que, FG1
de Swiet, M; Diakonov, I; Gorelik, J; Korchev, Y; Lab, M; Shevchuk, AI; Williamson, C1
Baisini, O; Benini, F; De Tavonatti, MG; Lanzarotto, F; Lanzini, A; Mora, A; Panarotto, B; Scalia, S1
Balakrishnan, A; Polli, JE; Wring, SA1
Cui, NQ; Li, DH; Sun, BJ; Wang, Q1
Adler, E; Bernstein, C; Bernstein, H; Condon, A; Dvorak, K; Goldman, A; Minnella, M1
Arias, IM; Fu, D; Lippincott-Schwartz, J; Wakabayashi, Y1
Bhakoo, K; Bowman, N; Brown, L; Chambers, J; Dixon, PH; Geenes, VL; Lim, YH; Tailor, H; Williamson, C; Wyatt-Ashmead, J1
Ikebuchi, Y; Ito, K; Shimizu, H; Suzuki, H; Takada, T; Yamanashi, Y; Yoshikado, T1
Gohlke, H; Häussinger, D; Reinehr, R; Schmitz, B; Sommerfeld, A1
Bennett, P; Harrison, S; Irish, M; Meng, M; Reuschel, S; Voelker, T; Wang, H; Wang, J1
Arase, Y; Hirose, S; Kagawa, T; Mine, T; Mizutani, A; Orii, R; Shiraishi, K; Tsukamoto, H1
Doleschal, B; Fauler, G; Groschner, K; Harenkamp, S; Pieske, BM; Primessnig, U; Rainer, PP; Stojakovic, T; Trauner, M; von Lewinski, D; Wachter, R; Wallner, M; Yates, A1
Barabanchyk, OV; Kozak, NP; Svintsits'kyĭ, AS1
Beuers, U; de Waart, DR; Duijst, S; Elferink, RP; Gilglioni, EH; Kaufman, C; Lempp, FA; Mier, W; Slijepcevic, D; Stieger, B; Urban, S; van de Graaf, SF; Wichers, CG1
Alvarez-Laviada, A; Bhogal, N; Chambers, J; Gorelik, J; Hasan, A; Miragoli, M; Poulet, C; Schultz, F; Wells, S; Williamson, C1
Adeyemi, O; Alvarez-Laviada, A; Glukhov, AV; Gorelik, J; Ibrahim, E; Schultz, F; Trauner, M; Williamson, C1
Cleal, JK; Garbis, SD; Lewis, RM; Lofthouse, EM; Manousopoulou, A; Nahar, M; O'Kelly, IM; Sengers, BG; Torrens, C1
Alahakoon, TI; Curnow, J; George, J; Heath, S; Lin, MW; Smet, ME; Wu, C1

Trials

4 trial(s) available for taurocholic acid and ursodeoxycholic acid

ArticleYear
Effect of chronic administration of ursodeoxycholic acid on the ileal absorption of endogenous bile acids in man.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:5

    Topics: Absorption; Adult; Bile Acids and Salts; Female; Humans; Ileum; Male; Middle Aged; Taurocholic Acid; Time Factors; Ursodeoxycholic Acid

1990
Ileal absorption of bile acids in patients with chronic cholestasis: SeHCAT test results and effect of ursodeoxycholic acid (UDCA).
    Digestive diseases and sciences, 1996, Volume: 41, Issue:12

    Topics: Alkaline Phosphatase; Bile Acids and Salts; Cholestasis; Chronic Disease; Down-Regulation; Female; gamma-Glutamyltransferase; Humans; Ileum; Intestinal Absorption; Liver Cirrhosis; Male; Middle Aged; Selenium Radioisotopes; Taurocholic Acid; Up-Regulation; Ursodeoxycholic Acid

1996
Ursocholic acid, a hydrophilic bile acid, fails to improve liver function parameters in primary biliary cirrhosis: comparison with ursodeoxycholic acid.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:6

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Fasting; Female; Humans; Liver; Liver Cirrhosis, Biliary; Placebos; Taurocholic Acid; Ursodeoxycholic Acid

1997
Effects of choleretics on bile compositions drained from patients with pigment gallstone.
    Chinese journal of integrative medicine, 2006, Volume: 12, Issue:2

    Topics: Adult; Bile; Bile Acids and Salts; Bilirubin; Calcium; Cholagogues and Choleretics; Choledochostomy; Cysteic Acid; Drainage; Drugs, Chinese Herbal; Female; Gallstones; Glucuronidase; Glycocholic Acid; Humans; Male; Middle Aged; Taurocholic Acid; Ursodeoxycholic Acid

2006

Other Studies

76 other study(ies) available for taurocholic acid and ursodeoxycholic acid

ArticleYear
Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver.
    Gastroenterology, 1995, Volume: 109, Issue:4

    Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Base Sequence; Carrier Proteins; Chromosomes, Human, Pair 12; Cloning, Molecular; DNA Probes; DNA, Complementary; Glycocholic Acid; Humans; Liver; Molecular Sequence Data; Oocytes; Rats; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurodeoxycholic Acid; Xenopus laevis

1995
Bile acid inhibition of P-glycoprotein-mediated transport in multidrug-resistant cells and rat liver canalicular membrane vesicles.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:1 Pt 1

    Topics: Animals; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Carcinoma, Hepatocellular; Carrier Proteins; Cell Membrane; Daunorubicin; Depression, Chemical; Doxorubicin; Drug Resistance; Liver Neoplasms; Male; Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Rhodamine 123; Rhodamines; Tumor Cells, Cultured

1994
Functional characterization of the basolateral rat liver organic anion transporting polypeptide.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:2

    Topics: Animals; Anion Transport Proteins; Bile Acids and Salts; Carrier Proteins; Female; In Vitro Techniques; Indocyanine Green; Ion Transport; Liver; Oocytes; Rats; Sulfobromophthalein; Xenopus laevis

1994
Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Chromosome Mapping; Cloning, Molecular; Humans; Liver; Molecular Sequence Data; Organic Anion Transporters, Sodium-Dependent; Symporters; Xenopus laevis

1994
Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells.
    The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 1

    Topics: Animals; Bile Acids and Salts; Blotting, Northern; Carrier Proteins; Cell Line; DNA, Complementary; Fluorescence; Liver; Microscopy, Fluorescence; Organic Anion Transporters, Sodium-Dependent; Rats; Symporters; Taurocholic Acid; Transfection

1994
Synthesis and physicochemical, biological, and pharmacological properties of new bile acids amidated with cyclic amino acids.
    Journal of medicinal chemistry, 1996, May-24, Volume: 39, Issue:11

    Topics: Amides; Animals; Bile; Bile Acids and Salts; Kinetics; Liver; Male; Molecular Structure; Proline; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Taurochenodeoxycholic Acid

1996
Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Amino Acid Sequence; Animals; Anions; Base Sequence; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cations, Monovalent; CHO Cells; Cloning, Molecular; COS Cells; Cricetinae; DNA, Complementary; Humans; Ileum; Kidney; Kinetics; Molecular Sequence Data; Organic Anion Transporters, Sodium-Dependent; Recombinant Proteins; RNA, Messenger; Sodium; Symporters; Taurocholic Acid; Transcription, Genetic; Transfection

1998
Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney.
    Molecular pharmacology, 1999, Volume: 55, Issue:4

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Kidney; Male; Membrane Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Oocytes; Organic Anion Transporters; Rats; Rats, Wistar; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Tissue Distribution; Transfection; Xenopus laevis

1999
Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Bile Acids and Salts; Biological Transport, Active; Carrier Proteins; Cells, Cultured; HeLa Cells; Humans; Kinetics; Liver; Nicotine; Organic Anion Transporters, Sodium-Dependent; Plasmids; RNA, Messenger; Salicylates; Symporters; Vaccinia virus; Valproic Acid

1999
Molecular cloning and characterization of the murine bile salt export pump.
    Gene, 2000, Jan-04, Volume: 241, Issue:1

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line; Cell Membrane; Cholagogues and Choleretics; Cholestasis; Cloning, Molecular; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Rats; Sequence Homology, Amino Acid; Taurocholic Acid; Transfection

2000
Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver.
    Gastroenterology, 2001, Volume: 121, Issue:1

    Topics: Administration, Oral; Animals; Bile Acids and Salts; Bile Ducts; Biological Transport; Cholic Acid; Down-Regulation; Gene Expression Regulation; Liver; Male; Mice; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation; Ursodeoxycholic Acid

2001
Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:5

    Topics: Animals; Anions; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cholagogues and Choleretics; HeLa Cells; Humans; Kinetics; Liver; Membrane Transport Proteins; Organic Anion Transporters, Sodium-Dependent; Organic Anion Transporters, Sodium-Independent; Rats; Serum Albumin, Bovine; Substrate Specificity; Sulfobromophthalein; Symporters; Taurocholic Acid; Transfection

2003
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
    Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Polarity; Cholagogues and Choleretics; Cricetinae; Fibroblasts; Gene Expression; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Rats; Taurocholic Acid; Transfection; Transport Vesicles; Tritium

2003
Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:1

    Topics: Adenoviridae; Animals; Bile Acids and Salts; Cell Culture Techniques; DNA, Complementary; Dogs; Hepatocytes; Humans; Kidney; Kinetics; Membrane Glycoproteins; Organic Anion Transporters, Sodium-Dependent; Rats; Sodium; Symporters; Transfection

2005
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Bile Acids and Salts; CHO Cells; Cricetinae; Cricetulus; Drug Design; Drug Evaluation, Preclinical; Hormones; Humans; Ligands; Models, Molecular; Molecular Conformation; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship

2008
Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Bile Acids and Salts; Cell Line; Cell Survival; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Esophagus; Humans; Hydrophobic and Hydrophilic Interactions; Structure-Activity Relationship

2010
Distinct effects of three bile salts on cholesterol solubilization by oleate-monoolein-bile salt micelles.
    Biochimica et biophysica acta, 1979, Nov-21, Volume: 575, Issue:2

    Topics: Bile Acids and Salts; Cholesterol; Colloids; Glycerides; Hydrogen-Ion Concentration; Micelles; Oleic Acids; Solubility; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1979
Microtubule-independent choleresis and anti-cholestatic action of tauroursodeoxycholate in colchicine-treated rat liver.
    The Biochemical journal, 1992, Dec-01, Volume: 288 ( Pt 2)

    Topics: Animals; Aspartate Aminotransferases; Bile; Cholestasis; Colchicine; gamma-Glutamyltransferase; Male; Microtubules; Rats; Rats, Inbred Strains; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1992
Immunomodulatory effects of ursodeoxycholic acid on immune responses.
    Hepatology (Baltimore, Md.), 1992, Volume: 16, Issue:2

    Topics: Adjuvants, Immunologic; Adult; Cytokines; Female; Humans; Immunoglobulins; Interleukin-1; Liver Cirrhosis, Biliary; Lymphocyte Activation; Male; Middle Aged; Taurocholic Acid; Tumor Cells, Cultured; Ursodeoxycholic Acid

1992
Effect of bile acids on ischemia-reperfusion liver injury.
    Journal of hepatology, 1991, Volume: 13, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Bile; Ischemia; Isomerism; L-Lactate Dehydrogenase; Liver Circulation; Male; Perfusion; Rats; Rats, Inbred Strains; Reperfusion Injury; Taurochenodeoxycholic Acid; Taurocholic Acid; Uric Acid; Ursodeoxycholic Acid

1991
Effect of ursodeoxycholic acid treatment on ileal absorption of bile acids in man as determined by the SeHCAT test.
    Gut, 1991, Volume: 32, Issue:9

    Topics: Adult; Bile Acids and Salts; Cholesterol; Dose-Response Relationship, Drug; Female; Humans; Ileum; Intestinal Absorption; Male; Middle Aged; Selenium Radioisotopes; Taurocholic Acid; Triglycerides; Ursodeoxycholic Acid

1991
Bile secretory characteristics of beta-muricholate and its taurine conjugate are similar to those of ursodeoxycholate in the rat.
    Life sciences, 1991, Volume: 48, Issue:10

    Topics: Animals; Bicarbonates; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Cholic Acids; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1991
Pre-replicative phase-related changes in bile acid-induced choleresis in the regenerating rat liver.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:1

    Topics: Animals; Bicarbonates; Bile; Cholagogues and Choleretics; Cholic Acids; Deoxycholic Acid; Hepatectomy; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1990
Addition of N-acetylcysteine to aqueous model bile systems accelerates dissolution of cholesterol gallstones.
    Gastroenterology, 1990, Volume: 98, Issue:2

    Topics: Acetylcysteine; Animals; Bile; Cattle; Cholelithiasis; Cholesterol; Expectorants; Humans; In Vitro Techniques; Taurocholic Acid; Ursodeoxycholic Acid

1990
Formation of biliary thrombi in protoporphyrin-induced cholestasis in perfused rat liver.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Diseases; Microscopy, Electron; Perfusion; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1990
Permeability of the rat biliary tree to ursodeoxycholic acid.
    The American journal of physiology, 1989, Volume: 256, Issue:4 Pt 1

    Topics: Absorption; Animals; Bile; Bile Ducts; Cell Membrane Permeability; Cholic Acid; Cholic Acids; Common Bile Duct; Deoxycholic Acid; Epithelium; Glucose; Kinetics; Liver; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Sucrose; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1989
Effect of bile salts on the plasma concentration of immunoreactive vasoactive intestinal polypeptide in man.
    Endocrinologia japonica, 1989, Volume: 36, Issue:1

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Duodenum; Humans; Intestinal Mucosa; Kinetics; Male; Radioimmunoassay; Taurocholic Acid; Ursodeoxycholic Acid; Vasoactive Intestinal Peptide

1989
N-acetylglucosaminides. A new type of bile acid conjugate in man.
    The Journal of biological chemistry, 1989, Aug-05, Volume: 264, Issue:22

    Topics: Acetylglucosamine; Bile Acids and Salts; Chromatography, High Pressure Liquid; Deoxycholic Acid; Gas Chromatography-Mass Spectrometry; Glucosamine; Glucosides; Glycocholic Acid; Glycosylation; Humans; Hydrolysis; Mass Spectrometry; Taurocholic Acid; Ursodeoxycholic Acid

1989
Quantitative assessment of canalicular bile formation in isolated hepatocyte couplets using microscopic optical planimetry.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:2

    Topics: Animals; Bile; Bile Canaliculi; Bile Ducts, Intrahepatic; Liver; Microscopy, Electron; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1989
Effect of lecithin on the release of 5'-nucleotidase from liver plasma membrane of rat by bile acids.
    Lipids, 1987, Volume: 22, Issue:1

    Topics: 5'-Nucleotidase; Animals; Bile Acids and Salts; Cell Membrane; Liver; Nucleotidases; Phosphatidylcholines; Rats; Rats, Inbred F344; Solubility; Taurine; Taurocholic Acid; Ursodeoxycholic Acid

1987
Importance of carbonic anhydrase for canalicular and ductular choleresis in the pig.
    Acta physiologica Scandinavica, 1988, Volume: 133, Issue:4

    Topics: Acetazolamide; Animals; Bicarbonates; Bile; Bile Canaliculi; Bile Ducts; Bile Ducts, Intrahepatic; Carbonic Anhydrases; Histocytochemistry; Liver; Secretin; Swine; Taurocholic Acid; Ursodeoxycholic Acid

1988
Prevention of endotoxaemia in obstructive jaundice--a comparative study of bile salts.
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1988, Volume: 1, Issue:1

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Deoxycholic Acid; Endotoxins; Escherichia coli; Glycodeoxycholic Acid; Intestinal Absorption; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Taurodeoxycholic Acid; Ursodeoxycholic Acid

1988
Effect of various bile salts on calcium concentration and calcium carbonate saturation of rat bile.
    Journal of hepatology, 1988, Volume: 7, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Calcium; Calcium Carbonate; Glycocholic Acid; Male; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1988
Effect of protoporphyrin IX on ursodeoxycholate-induced hypercholeresis in the rat.
    Clinical science (London, England : 1979), 1988, Volume: 75, Issue:6

    Topics: Animals; Bicarbonates; Bile; Deoxycholic Acid; Dose-Response Relationship, Drug; Male; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1988
The effect of amiloride on biliary HCO3- secretion in the anaesthetized pig.
    Acta physiologica Scandinavica, 1987, Volume: 130, Issue:3

    Topics: Amiloride; Animals; Bicarbonates; Bile; Biliary Tract; Ion Exchange; Liver; Secretin; Secretory Rate; Swine; Taurocholic Acid; Ursodeoxycholic Acid

1987
Pancreatic exocrine secretion in response to intraduodenal infusion of different detergent agents in anesthetized cats.
    Digestion, 1986, Volume: 34, Issue:2

    Topics: Animals; Bile Acids and Salts; Cats; Detergents; Duodenum; Micelles; Oleic Acid; Oleic Acids; Pancreas; Perfusion; Surface Tension; Surface-Active Agents; Taurocholic Acid; Ursodeoxycholic Acid

1986
Improved enzymatic hydrolysis of conjugated bile acids.
    Lipids, 1987, Volume: 22, Issue:1

    Topics: Amidohydrolases; Bile Acids and Salts; Humans; Micelles; Octoxynol; Polyethylene Glycols; Taurine; Taurocholic Acid; Ursodeoxycholic Acid

1987
Effects of Na+ replacement and amiloride on ursodeoxycholic acid-stimulated choleresis and biliary bicarbonate secretion.
    The American journal of physiology, 1987, Volume: 252, Issue:2 Pt 1

    Topics: Amiloride; Animals; Bicarbonates; Bile; Chlorides; Deoxycholic Acid; Kinetics; Lithium; Liver; Potassium; Rats; Sodium; Taurocholic Acid; Ursodeoxycholic Acid

1987
Effect of side-chain shortening on the physiologic properties of bile acids: hepatic transport and effect on biliary secretion of 23-nor-ursodeoxycholate in rodents.
    Gastroenterology, 1986, Volume: 90, Issue:4

    Topics: Animals; Bile Acids and Salts; Biliary Tract; Biological Transport; Cholesterol; Cricetinae; Guinea Pigs; Liver; Male; Phospholipids; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1986
Bile acid therapies applied to patients suffering from cerebrotendinous xanthomatosis.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Oct-31, Volume: 152, Issue:1-2

    Topics: Adult; Aged; Bile Acids and Salts; Brain Diseases; Chenodeoxycholic Acid; Cholestanols; Cholic Acid; Cholic Acids; Female; Humans; Male; Middle Aged; Taurocholic Acid; Tendons; Ursodeoxycholic Acid; Xanthomatosis

1985
Inhibitory effect of unconjugated bile acids on the intestinal transport of 5-methyltetrahydrofolate in rat jejunum in vitro.
    Gut, 1984, Volume: 25, Issue:12

    Topics: Animals; Bile Acids and Salts; Biological Transport; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Deoxycholic Acid; In Vitro Techniques; Jejunum; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Tetrahydrofolates; Time Factors; Ursodeoxycholic Acid

1984
Glycoursodeoxycholate is as effective as tauroursodeoxycholate in preventing the taurocholate-induced cholestasis in the rat.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 42, Issue:3

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Drug Evaluation, Preclinical; Rats; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1983
Conjugation is rate limiting in hepatic transport of ursodeoxycholate in the rat.
    The American journal of physiology, 1982, Volume: 243, Issue:3

    Topics: Animals; Bile Acids and Salts; Biological Transport; Cholic Acids; Chromatography, Thin Layer; Deoxycholic Acid; Liver; Male; Rats; Rats, Inbred Strains; Taurine; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1982
Effect of ursodeoxycholate on the bile flow in the rat.
    Life sciences, 1982, Nov-01, Volume: 31, Issue:18

    Topics: Animals; Bile; Bile Acids and Salts; Biological Transport; Deoxycholic Acid; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1982
Thin-layer chromatographic separation of conjugates of ursodeoxycholic acid from those of litho-, chenodeoxy-, deoxy-, and cholic acids.
    Journal of lipid research, 1981, Volume: 22, Issue:4

    Topics: Chenodeoxycholic Acid; Chromatography, Thin Layer; Deoxycholic Acid; Glycine; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Lithocholic Acid; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid; Ursodeoxycholic Acid

1981
Hypercholeresis induced by ursodeoxycholic acid and 7-ketolithocholic acid in the rat: possible role of bicarbonate transport.
    Gastroenterology, 1980, Volume: 79, Issue:1

    Topics: Animals; Bicarbonates; Bile; Bile Acids and Salts; Biliary Tract; Cholagogues and Choleretics; Cholic Acids; Dehydrocholic Acid; Deoxycholic Acid; Electrolytes; Lithocholic Acid; Male; Osmosis; Rats; Taurocholic Acid; Ursodeoxycholic Acid

1980
Effects of biliary bile acid composition on biliary cholesterol saturation in gallstone patients treated with chenodeoxycholic acid and/or ursodeoxycholic acid.
    Gastroenterology, 1980, Volume: 79, Issue:6

    Topics: Aged; Anticholesteremic Agents; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Deoxycholic Acid; Drug Therapy, Combination; Female; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Male; Middle Aged; Solubility; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1980
Tubulovesicular transport of horseradish peroxidase in isolated rat hepatocyte couplets: effects of low temperature, cytochalasin B and bile acids.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:4 Pt 1

    Topics: Animals; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Cells, Cultured; Cytochalasin B; Cytoplasmic Granules; Histocytochemistry; Horseradish Peroxidase; Liver; Male; Microscopy, Electron; Microtubules; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid; Temperature; Ursodeoxycholic Acid

1994
Competition of bile acids on the sulfobromophthalein uptake in basolateral rat liver plasma membrane vesicles.
    Biochemical pharmacology, 1994, Sep-15, Volume: 48, Issue:6

    Topics: Animals; Bile Acids and Salts; Cell Membrane; Cholic Acid; Cholic Acids; Dose-Response Relationship, Drug; Female; Liver; Membrane Potentials; Rats; Rats, Wistar; Sulfobromophthalein; Taurocholic Acid; Ursodeoxycholic Acid

1994
Effects of selective zonal injury on bile acid-induced bile flow in the isolated rat liver.
    The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 1

    Topics: Animals; Bile; Bile Acids and Salts; Biotransformation; Chenodeoxycholic Acid; Cholagogues and Choleretics; In Vitro Techniques; Liver; Liver Diseases; Male; Rats; Rats, Wistar; Taurocholic Acid; Ursodeoxycholic Acid

1993
Tubulovesicular transcytotic pathway in rat biliary epithelium: a study in perfused liver and in isolated intrahepatic bile duct.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:2

    Topics: Animals; Bile Ducts, Intrahepatic; Colchicine; Epithelial Cells; Epithelium; Horseradish Peroxidase; Liver; Lumicolchicines; Male; Microscopy, Electron; Perfusion; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Ursodeoxycholic Acid

1993
Medication with ursodeoxycholic acid enhances the biliary clearance of polyethylene glycol 900, but not mannitol.
    Digestion, 1995, Volume: 56, Issue:5

    Topics: Adult; Aged; Bile; Carbon Radioisotopes; Cholagogues and Choleretics; Female; Humans; Male; Mannitol; Middle Aged; Polyethylene Glycols; Regression Analysis; Taurocholic Acid; Tritium; Ursodeoxycholic Acid

1995
Intestinal absorption of bile acids in the rabbit: different transport rates in jejunum and ileum.
    Gastroenterology, 1996, Volume: 110, Issue:2

    Topics: Animals; Bile Acids and Salts; Biological Transport, Active; Chenodeoxycholic Acid; Cholesterol; Deoxycholic Acid; Diffusion; Ileum; Intestinal Absorption; Jejunum; Male; Membrane Fluidity; Membrane Lipids; Microvilli; Phospholipids; Rabbits; Taurocholic Acid; Ursodeoxycholic Acid

1996
cGMP stimulates bile acid-independent bile formation and biliary bicarbonate excretion.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Arginine Vasopressin; Bicarbonates; Bile; Bile Acids and Salts; Calcium; Cells, Cultured; Choline; Cyclic AMP; Cyclic GMP; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Oxygen Consumption; Rats; Rats, Wistar; Taurocholic Acid; Thionucleotides; Ursodeoxycholic Acid

1996
Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:3

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Cyclosporine; Fasting; Female; Glycocholic Acid; Heart Transplantation; Hepatitis, Chronic; Humans; Immunosuppressive Agents; Lithocholic Acid; Male; Middle Aged; Spectrophotometry, Ultraviolet; Taurocholic Acid; Ursodeoxycholic Acid

1996
Use of 1H NMR spectroscopy (T2 relaxation times) to examine the effects of conjugated ursodeoxycholic acid on phospholipid fluidity of human gallbladder bile.
    Biochemical Society transactions, 1997, Volume: 25, Issue:1

    Topics: Bile; Bile Acids and Salts; Cholecystectomy; Gallbladder; Glycochenodeoxycholic Acid; Glycodeoxycholic Acid; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Micelles; Phospholipids; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1997
Effect of cholestasis on regulation of cAMP synthesis by glucagon and bile acids in isolated hepatocytes.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Angiotensin II; Animals; Bile; Bile Acids and Salts; Cells, Cultured; Cholestasis; Colforsin; Common Bile Duct; Cricetinae; Cyclic AMP; Glucagon; Isoenzymes; Kinetics; Liver; Male; Mesocricetus; Protein Kinase C; Protein Kinase C-alpha; Receptors, Glucagon; Reference Values; Taurocholic Acid; Ursodeoxycholic Acid

1997
Effects of ursodeoxycholate and other bile salts on levels of rat intestinal alkaline sphingomyelinase: a potential implication in tumorigenesis.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:1

    Topics: Administration, Oral; Animals; Bile Acids and Salts; Cholic Acids; Colonic Neoplasms; Glycochenodeoxycholic Acid; Glycocholic Acid; Intestinal Mucosa; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase; Taurocholic Acid; Taurodeoxycholic Acid; Ursodeoxycholic Acid

1998
GUDC inhibits cytochrome c release from human cholangiocyte mitochondria.
    The Journal of surgical research, 1999, May-15, Volume: 83, Issue:2

    Topics: Anti-Bacterial Agents; Apoptosis; Bile Ducts; Carrier Proteins; Caspase 3; Caspases; Cell Line; Cytochrome c Group; Depsipeptides; Gene Expression Regulation, Enzymologic; Humans; Hydroxysteroid Dehydrogenases; Membrane Glycoproteins; Mitochondria; Peptides; Protein Processing, Post-Translational; Reverse Transcriptase Polymerase Chain Reaction; Taurocholic Acid; Ursodeoxycholic Acid

1999
Dexamethasone and ursodeoxycholic acid protect against the arrhythmogenic effect of taurocholate in an in vitro study of rat cardiomyocytes.
    BJOG : an international journal of obstetrics and gynaecology, 2003, Volume: 110, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cholagogues and Choleretics; Dexamethasone; Dose-Response Relationship, Drug; Myocardial Contraction; Myocardium; Rats; Taurocholic Acid; Ursodeoxycholic Acid

2003
Intestinal absorption of the bile acid analogue 75Se-homocholic acid-taurine is increased in primary biliary cirrhosis, and reverts to normal during ursodeoxycholic acid administration.
    Gut, 2003, Volume: 52, Issue:9

    Topics: Adult; Aged; Bile Acids and Salts; Cholagogues and Choleretics; Female; Humans; Ileum; Intestinal Absorption; Liver Cirrhosis, Biliary; Middle Aged; Selenium Radioisotopes; Taurine; Taurocholic Acid; Ursodeoxycholic Acid

2003
Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation.
    Pharmaceutical research, 2006, Volume: 23, Issue:7

    Topics: Amination; Animals; Bile Acids and Salts; Biological Transport; Cell Line; Chenodeoxycholic Acid; Dogs; Glycine; Hydroxylation; Kinetics; Organic Anion Transporters, Sodium-Dependent; Permeability; Quantitative Structure-Activity Relationship; Symporters; Taurine; Taurocholic Acid; Transfection; Ursodeoxycholic Acid

2006
Protective effects of glycoursodeoxycholic acid in Barrett's esophagus cells.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2010, Volume: 23, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Barrett Esophagus; Bile Acids and Salts; Cell Line; Cell Proliferation; Cell Survival; Cytoprotection; Deoxycholic Acid; Deoxyguanosine; DNA Damage; Esophagus; Free Radical Scavengers; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Hydrogen-Ion Concentration; Oxidative Stress; Protective Agents; Reactive Oxygen Species; RNA; Sulfhydryl Compounds; Superoxide Dismutase; Taurocholic Acid; Time Factors; Ursodeoxycholic Acid

2010
Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jan-25, Volume: 108, Issue:4

    Topics: Adenylate Kinase; AMP-Activated Protein Kinase Kinases; Animals; Bile Acids and Salts; Blotting, Western; Cell Polarity; Cells, Cultured; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cyclic AMP; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Hepatocytes; Imines; Microscopy, Confocal; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Protein Serine-Threonine Kinases; rap1 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Taurocholic Acid; Ursodeoxycholic Acid

2011
A placental phenotype for intrahepatic cholestasis of pregnancy.
    Placenta, 2011, Volume: 32, Issue:12

    Topics: Cholestasis, Intrahepatic; Female; Humans; Phenotype; Placenta; Pregnancy; Pregnancy Complications; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

2011
Ursodeoxycholic acid stimulates the formation of the bile canalicular network.
    Biochemical pharmacology, 2012, Oct-01, Volume: 84, Issue:7

    Topics: Animals; Biliary Tract; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Hepatocytes; Male; MAP Kinase Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Rats; Rats, Wistar; Taurocholic Acid; Ursodeoxycholic Acid

2012
α5 β1-integrins are sensors for tauroursodeoxycholic acid in hepatocytes.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:3

    Topics: Allosteric Regulation; Animals; Dimerization; Green Fluorescent Proteins; Hep G2 Cells; Hepatocytes; Humans; Integrin alpha5beta1; Male; MAP Kinase Signaling System; Oligopeptides; Organic Anion Transporters, Sodium-Dependent; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Rats, Wistar; RNA, Small Interfering; Structure-Activity Relationship; Symporters; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

2013
Method development and validation of six bile acids for regulated bioanalysis: improving selectivity and sensitivity.
    Bioanalysis, 2013, Volume: 5, Issue:10

    Topics: Bile Acids and Salts; Biomarkers; Blood Proteins; Chenodeoxycholic Acid; Cholic Acid; Chromatography, Liquid; Deoxycholic Acid; Humans; Lithocholic Acid; Sensitivity and Specificity; Tandem Mass Spectrometry; Taurocholic Acid; Ursodeoxycholic Acid; Validation Studies as Topic

2013
Ursodeoxycholic acid stabilizes the bile salt export pump in the apical membrane in MDCK II cells.
    Journal of gastroenterology, 2014, Volume: 49, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Cell Membrane; Cholestasis, Intrahepatic; Dogs; Endocytosis; Hepatocytes; Madin Darby Canine Kidney Cells; Mutation; Rats; Taurocholic Acid; Ursodeoxycholic Acid

2014
Bile acids induce arrhythmias in human atrial myocardium--implications for altered serum bile acid composition in patients with atrial fibrillation.
    Heart (British Cardiac Society), 2013, Volume: 99, Issue:22

    Topics: Aged; Animals; Atrial Fibrillation; Bile Acids and Salts; Cardiac Electrophysiology; Female; Heart Atria; Humans; Male; Mice; Myocytes, Cardiac; Taurocholic Acid; Ursodeoxycholic Acid

2013
[CORRECTION OF BILE FLOW CHARACTERISTICS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE IN COMBINATION WITH HYPERURICEMIA].
    Likars'ka sprava, 2014, Issue:11

    Topics: Adult; Allopurinol; Bile; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Cholesterol; Cholic Acid; Deoxycholic Acid; Drug Therapy, Combination; Duodenoscopy; Female; Fluorobenzenes; Humans; Hyperuricemia; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Pyrimidines; Rosuvastatin Calcium; Sulfonamides; Taurocholic Acid; Uric Acid; Ursodeoxycholic Acid

2014
Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.
    Hepatology (Baltimore, Md.), 2015, Volume: 62, Issue:1

    Topics: Animals; Bile; Feces; Female; Hepatitis B virus; Lipopeptides; Liver; Male; Mice, Knockout; Organic Anion Transporters, Sodium-Dependent; Phenotype; Symporters; Taurocholic Acid; Ursodeoxycholic Acid; Viral Envelope Proteins

2015
The protective effect of ursodeoxycholic acid in an in vitro model of the human fetal heart occurs via targeting cardiac fibroblasts.
    Progress in biophysics and molecular biology, 2016, Volume: 120, Issue:1-3

    Topics: Animals; Animals, Newborn; Calcium; Cell Hypoxia; Cell Separation; Cytoprotection; Fetal Heart; Fibroblasts; Humans; Membrane Potentials; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Ursodeoxycholic Acid

2016
Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Animals; Calcium; Calcium Channels, T-Type; Cholestasis; Electrophysiological Phenomena; Female; Fetal Heart; Heart Ventricles; Humans; Myocytes, Cardiac; Pregnancy; Rats; Taurocholic Acid; Ursodeoxycholic Acid

2017
Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:7

    Topics: Animals; Autophagic Cell Death; Female; Humans; Male; Organic Anion Transporters; Oxidative Stress; Placenta; Pregnancy; Rats; Rats, Wistar; Taurocholic Acid; Ursodeoxycholic Acid; Vasoconstriction; Xenopus laevis

2019
Pregnancy complicated by refractory severe hypercholanaemia from sodium taurocholate co-transporting polypeptide deficiency.
    The journal of obstetrics and gynaecology research, 2021, Volume: 47, Issue:2

    Topics: Bile Acids and Salts; Cholestasis, Intrahepatic; Female; Humans; Infant, Newborn; Peptides; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Taurocholic Acid; Ursodeoxycholic Acid

2021