taurocholic acid has been researched along with taurochenodeoxycholic acid in 158 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (29.11) | 18.7374 |
| 1990's | 74 (46.84) | 18.2507 |
| 2000's | 25 (15.82) | 29.6817 |
| 2010's | 10 (6.33) | 24.3611 |
| 2020's | 3 (1.90) | 2.80 |
| Authors | Studies |
|---|---|
| Foguet, M; Hagenbuch, B; Lübbert, H; Meier, PJ; Stieger, B | 1 |
| Hagenbuch, B; Hofmann, AF; Kullak-Ublick, GA; Meier, PJ; Schteingart, CD; Stieger, B; Wolkoff, AW | 1 |
| Arias, IM; Fantappié, O; Gatmaitan, Z; Gentilini, P; Kamimoto, Y; Mazzanti, R | 1 |
| Hagenbuch, B; Kullak-Ublick, GA; Meier, PJ; Stieger, B; Wolkoff, AW | 1 |
| Hagenbuch, B; Meier, PJ | 1 |
| Eckhardt, U; Hagenbuch, B; Meier, PJ; Schroeder, A; Stieger, B | 1 |
| Craddock, AL; Daniel, RW; Dawson, PA; Kirby, LC; Love, MW; Walters, HC; Wong, MH | 1 |
| Eckhardt, U; Hagenbuch, B; Hofmann, AF; Meier, PJ; Schroeder, A; Schteingart, CD; Stieger, B; Tynes, R | 1 |
| Hashimoto, Y; Ibaramoto, K; Inui, KI; Masuda, S; Saito, H; Takeuchi, A | 1 |
| Eckhardt, U; Hagenbuch, B; Höchli, M; Landmann, L; Meier, PJ; Schroeder, A; Stieger, B; Tynes, R | 1 |
| Green, RM; Hoda, F; Ward, KL | 1 |
| Craddock, AL; Dawson, PA; Fusegawa, H; Walters, HC; Willingham, MC | 1 |
| Hagenbuch, B; Meier, PJ; Noe, J; St-Pierre, MV | 1 |
| Borst, P; Bot, I; Kuil, A; Saeki, T; Zelcer, N | 1 |
| Byrne, JA; Higgins, CF; Linton, KJ; Mieli-Vergani, G; Strautnieks, SS; Thompson, RJ | 1 |
| Borst, P; Kuil, A; Reid, G; Schuetz, JD; van der Heijden, I; Wielinga, P; Zelcer, N | 1 |
| Ananthanarayanan, M; Batta, A; Eftychiou, N; Hata, S; Pang, KS; Salen, G; Wang, P; Wolkoff, AW | 1 |
| Hummel-Eisenbeiss, J; Jedlitschky, G; Keppler, D; Nies, AT; Rius, M | 1 |
| Akita, H; Hofmann, AF; Meier, PJ; Mita, S; Stieger, B; Sugiyama, Y; Suzuki, H | 1 |
| Auwerx, J; Gioiello, A; Hofmann, AF; Macchiarulo, A; Pellicciari, R; Saladin, R; Sato, H; Schoonjans, K; Thomas, C; Une, M | 1 |
| Gilmer, JF; Keaveney, R; Kelleher, D; Long, A; Majer, F; Peta, VK; Sharma, R; Wang, J | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fent, K; Popovic, M; Smital, T; Zaja, R | 1 |
| Anwer, MS; Hegner, D; Kroker, R | 1 |
| Gerolami, A; Montet, AM; Montet, JC; Reynier, MO | 1 |
| Ammon, HV | 1 |
| Binet, S; Delage, Y; Erlinger, S | 1 |
| Okuyama, S | 1 |
| Drew, R; Priestly, BG | 1 |
| Levin, SS; Levitt, RE; Soloway, RD; Touchstone, JC | 1 |
| Elliott, WH; Shaw, R; Smith, JA | 1 |
| Bochenek, W; Loiudice, TA; O'Connor, PJ; Rodgers, JB | 1 |
| Bunting, PS; Gall, DG; Hill, JG; Khan, M; Shepherd, RW; Soldin, SJ | 1 |
| Böhmer, R; Raffler, H | 1 |
| Crowther, RS; Qiu, SM; Soloway, RD | 1 |
| Hayakawa, T; Hoshino, M; Katagiri, K; Nakai, T; Ohiwa, T | 2 |
| Bernstein, C; Zheng, ZY | 1 |
| Gerok, W; Hallbrucker, C; Häussinger, D; Lang, F; Saha, N | 1 |
| Killenberg, PG; Lack, L; Ribeiro, AA; Stevens, RD | 1 |
| Abernathy, CO; Gillespie, J; Tripodi, MF; Utili, R; Zimmerman, HJ | 1 |
| Ballet, F; Bonnefis, MT; Chazouillères, O; Chrétien, Y; Legendre, C; Poupon, R; Rey, C | 1 |
| Killenberg, PG; Lack, L; Stevens, RD | 1 |
| Batta, AK; Hauser, S; Ness, GC; Nguyen, LB; Rani, I; Salen, G; Shefer, S; Tint, GS | 1 |
| Coche, T; Depiereux, E; Deroubaix, X; Feytmans, E | 2 |
| Kanai, S; Kitani, K; Ohta, M; Sato, Y; Schmucker, DL | 1 |
| Alvaro, D; Angelico, M; De Sanctis, SC; Gandin, C | 1 |
| Abernathy, CO; Adinolfi, LE; Gaeta, GB; Tripodi, MF; Utili, R; Zimmerman, HJ | 1 |
| Arora, R; Batta, AK; Batta, M; Person, A; Salen, G; Shefer, S | 1 |
| Fraser, S; McLeod, L; Roberts, MS; Wagner, A | 1 |
| Corbic, M; Dumont, M; Erlinger, S; Farges, O; Maurice, M | 1 |
| Ditschuneit, H; Scheibner, J; Stange, EF | 1 |
| Aldini, R; Lenzi, P; Roda, A; Roda, E; Simoni, P | 1 |
| Loretz, CA; Mooney, SM | 1 |
| Kanai, S; Kitani, K; Ohta, M | 1 |
| Chijiiwa, K; Fukudome, K; Kiyosawa, R; Nakayama, F | 1 |
| Gérolami, A; Marteau, C; Mathieu, S; Pauli, AM; Portugal, H | 1 |
| Cole, MJ; Shaffer, EA | 1 |
| Enserink, M; Fevery, J; Hardonk, MJ; Havinga, R; Kuipers, F; van der Steen, AB; Vonk, RJ | 1 |
| Devinuto, D; Morrison, C; Spivak, W; Yuey, W | 1 |
| Al-Bazzaz, FJ; Goldstein, JL; Layden, TJ; Schmidt, LN | 1 |
| Ananthanarayanan, M; Drain, P; Levy, D; von Dippe, P | 1 |
| Kanai, S; Kitani, K; Ohta, M; Sato, Y | 3 |
| Arisaka, O; Kato, H; Miyano, T; Nakatsu, N; Niijima, S; Nittono, H; Obinata, K; Sasaki, H; Watanabe, T; Yabuta, K | 1 |
| Andersen, JR; Hesselfeldt, P; Linnet, K | 1 |
| Kanai, S; Kitani, K | 4 |
| Linnet, K; Mertz Nielsen, A | 1 |
| Simmonds, WJ; Watt, SM | 1 |
| Konno, Y; Nakagawa, M; Tada, K; Tazawa, Y; Yamada, M | 1 |
| Croke, JC; Tompkins, RK | 1 |
| Beckett, GJ; Botham, KM; Boyd, GS; Williamson, D | 1 |
| Kivilaakso, E; Salo, JA | 1 |
| Botham, KM; Boyd, GS | 1 |
| Bontemps, R; Crotte, C; Gerolami, A; Lindheimer, M; Montet, JC; Reynier, MO | 1 |
| Dumont, M; Erlinger, S; Zouboulis-Vafiadis, I | 1 |
| Aldini, R; Barbara, L; Festi, D; Mazzella, G; Morselli, AM; Roda, A; Roda, E; Sama, C; Scopinaro, N | 1 |
| Beckett, GJ; Botham, KM; Boyd, GS; Lawson, ME; Percy-Robb, IW | 1 |
| Crotte, C; Gerolami, A; Marteau, C; Montet, JC; Reynier, MO | 1 |
| Batta, AK; Salen, G; Shefer, S | 1 |
| Czygan, P; Götz, R; Kommerell, B; Männer, C; Raedsch, R; Stiehl, A; Walker, S | 1 |
| Baele, G; Barbier, F; Beke, R | 1 |
| Frederiks, WM; Groen, AK; Oude Elferink, RP; Schinkel, AH; Smit, JJ; Van Wijland, MJ | 1 |
| Devereaux, MW; McKim, JM; Sokol, RJ; Winklhofer-Roob, BM | 1 |
| Alvaro, D; Benedetti, A; Bini, A; Capocaccia, L; Della Guardia, P; Gigliozzi, A; Jezequel, AM; La Rosa, T | 1 |
| Sano, N; Takikawa, H; Yamanaka, M; Yamazaki, R | 1 |
| Azzouz, H; Groen, AK; Klinkspoor, JH; Kuver, R; Lee, SP; Oda, D; Savard, CE; Tytgat, GN | 1 |
| Aldini, R; Cerre, C; Galletti, G; Lenzi, PL; Montagnani, M; Polimeni, C; Roda, A; Roda, E | 1 |
| Gondo, K; Harada, M; Sakisaka, S; Tanikawa, K; Yoshitake, M | 1 |
| Hayakawa, T; Hirano, A; Hoshino, M; Inagaki, T; Kamiya, Y; Kumai, T; Miyaji, M; Ohiwa, T; Takeuchi, T; Tanaka, A | 1 |
| Angelico, M; Baiocchi, L; Della Guardia, P; Franchitto, A; Gaudio, E; Nistri, A | 1 |
| Batta, A; Chowdhary, IR; Hauser, S; Ness, GC; Nguyen, LB; Paroulek, E; Salen, G; Shefer, S | 1 |
| Azer, SA; McCaughan, GW; Stacey, NH | 1 |
| Kishinaka, M; Kuroki, S; Umeda, A | 1 |
| Ishida, T; Kaneko, JJ; Tomoda, I; Washizu, M; Washizu, T | 1 |
| Hayakawa, T; Hirano, A; Hoshino, M; Kamiya, Y; Katagiri, K; Kumai, T; Miyaji, M; Ohiwa, T; Takeuchi, T; Tanaka, A | 1 |
| Beuers, U; Boyer, JL; Isales, CM; Nathanson, MH | 1 |
| Schwartz, CC; Shamburek, RD | 1 |
| Erickson, SK; Van Zuiden, PE | 1 |
| Anderson, MS; Beuers, U; Boyer, JL; Isales, CM; Koebe, HG; Kullak-Ublick, GA; Paumgartner, G; Sauter, G; Thasler, W; Throckmorton, DC | 1 |
| Aldini, R; Caruso, ML; Gioacchini, AM; Lenzi, PL; Montagnani, M; Roda, A; Roda, E | 1 |
| Groen, AK; Klinkspoor, JH; Lee, SP; Tytgat, GN | 1 |
| Bajaj, RS; Heuman, DM; Lin, Q | 1 |
| Davis, RA; Dueland, S; Lewis, KD; Moore, GL; Simon, FR; Trawick, JD | 1 |
| Gurley, EC; Hylemon, PB; Jarvis, WD; Rao, YP; Stravitz, RT; Vlahcevic, ZR | 1 |
| Gadellaa, M; Portincasa, P; Renooij, W; Van Berge Henegouwen, GP; Van de Heijning, BJ; Van Erpecum, KJ | 1 |
| Bolder, U; Frick, E; Hofmann, AF; Schteingart, CD; Ton-Nu, HT | 1 |
| Moseley, RH | 1 |
| Boyer, JL; Gartung, C; Schlosser, SF; Schuele, S | 1 |
| Ellul, JP; Gilani, SS; Murphy, GM | 1 |
| Aiso, M; Sano, N; Takamori, Y; Takikawa, H; Yamanaka, M | 1 |
| Kaler, EW; Lee, SP; Luk, AS | 1 |
| van Berge-Henegouwen, GP; van de Heijning, BJ; van den Broek, AM | 1 |
| Crocenzi, FA; Pellegrino, JM; Roma, MG; Sisti, A | 1 |
| Häussinger, D; Kurz, AK; Schliess, F; vom Dahl, S | 1 |
| Gurley, EC; Hylemon, PB; Rao, YP; Sando, JJ; Stravitz, RT; Vlahcevic, ZR | 1 |
| Baraldini, M; Cantelli Forti, G; Cerré, C; Guerra, MC; Piazza, F; Roda, A; Speroni, E | 1 |
| Jones, JD; Zollman, PE | 1 |
| Lee, BL; New, AL; Ong, CN | 1 |
| Kimura, J; Koike, M; Matsue, H; Matsushita, M; Noto, H; Takahashi, M; Todo, S | 1 |
| Bolufer, J; Coleto, R; Vazquez, CM | 1 |
| Klinkspoor, JH; Lee, SP; Yoshida, T | 1 |
| Kajiyama, G; Miura, H; Miyake, H; Tazuma, S; Yamashita, G | 1 |
| Amelsberg, A; Fölsch, UR; Jochims, C; Nitsche, R; Richter, CP | 1 |
| Fadden, K; Hill, MJ; Latymer, E; Low, G; Owen, RW | 1 |
| Angelico, M; Badr, SG; Cioli, D; Moroni, R; Pica-Mattoccia, L | 1 |
| DeMaria, EJ; Heuman, DM; Narain, PK | 1 |
| Bouchard, G; Tuchweber, B; Yousef, IM | 1 |
| Carlos, M; Rao, MC; Rasenick, MM; Selvaraj, N; Skaluba, S; Venkatasubramanian, J | 1 |
| Akita, H; Ito, K; Kinoshita, S; Sato, N; Sugiyama, Y; Suzuki, H; Takikawa, H | 1 |
| Balint, JA; Beeler, DA; Sarfeh, IJ; Treble, DH | 1 |
| Graf, D; Häussinger, D; Kurz, AK; Schmitt, M; Vom Dahl, S | 1 |
| Fuchs, M; Scheibner, J; Stange, EF | 1 |
| Huisman, SJ; Moschetta, A; van Erpecum, KJ; vanBerge-Henegouwen, GP; Venneman, NG | 1 |
| Higuchi, WI; Liu, CL | 1 |
| Desmoulière, A; Lamireau, T; Levy, E; Rosenbaum, J; Tuchweber, B; Yousef, I; Zoltowska, M | 1 |
| Ballatori, N; Boyer, J; Elferink, RP; Fricker, G; Ottenhoff, R; Seward, DJ | 1 |
| Chayama, K; Hyogo, H; Komichi, D; Nishioka, T; Tazuma, S; Une, M | 1 |
| Barrow, SL; Gerasimenko, OV; Petersen, OH; Tepikin, AV; Voronina, SG | 1 |
| Sano, N; Tachizawa, H; Takikawa, H | 1 |
| Sano, N; Takayanagi, M; Takikawa, H | 1 |
| Groen, AK; Kosters, A; Kunne, C; Looije, N; Oude Elferink, RP; Patel, SB | 1 |
| Gowda, GA; Ijare, OB; Kapoor, VK; Khetrapal, CL; Sharma, A; Somashekar, BS | 1 |
| Chen, CC; Hu, ZB; Ji, LL; Wang, JM; Wang, ZT; Xu, Y; Yang, L | 1 |
| Bhakoo, K; Bowman, N; Brown, L; Chambers, J; Dixon, PH; Geenes, VL; Lim, YH; Tailor, H; Williamson, C; Wyatt-Ashmead, J | 1 |
| Berlage, T; Domanova, O; Häussinger, D; Helmer, A; Keitel, V; Kubitz, R; Mühlfeld, S; Stross, C | 1 |
| Gohlke, H; Häussinger, D; Reinehr, R; Schmitz, B; Sommerfeld, A | 1 |
| Horenko, ZA; Hrinchenko, OA; Karbovs'ka, LS; Makarchuk, MIu; Vasheka, IP; Vesel'skyĭ, SP | 1 |
| Chen, W; Ge, K; Huang, F; Jia, W; Lei, S; Liu, J; Liu, P; Su, M; Wang, X; Xie, G; Yan, J; Zhang, Y; Zhao, A; Zheng, X | 1 |
| Ballauff, A; Burdelski, M; Dröge, C; Ellinger, P; Häussinger, D; Herebian, D; Kluge, S; Kubitz, R; Mayatepek, E; Sattler, K; Schmitt, L; Schulte Am Esch, J; Schulz-Jürgensen, S; Smits, SHJ; Stindt, J; Stross, C | 1 |
| Chen, H; Dai, Y; Gan, Q; Lai, L; Liao, S; Liu, F; Ou, M; Sui, W; Wang, B; Yang, M | 1 |
| Chen, BY; Guo, CF; Wang, XJ; Yang, BW; Yue, TL | 1 |
| Chen, H; Gu, Y; Hu, S; Jiang, B; Jin, M; Li, G; Lin, L; Lu, E; Mao, C; Tang, J; Yang, R; Yu, W | 1 |
1 review(s) available for taurocholic acid and taurochenodeoxycholic acid
| Article | Year |
|---|---|
Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver.
Topics: Animals; Anion Transport Proteins; Anions; Bile Acids and Salts; Carrier Proteins; Cloning, Molecular; Humans; Liver; Membrane Transport Proteins; Models, Molecular; Organic Anion Transporters, Sodium-Dependent; Rats; Substrate Specificity; Symporters | 1997 |
1 trial(s) available for taurocholic acid and taurochenodeoxycholic acid
| Article | Year |
|---|---|
Daily determination of individual serum bile acids allows early detection of hepatic allograft dysfunction.
Topics: Adolescent; Adult; Aged; Bile Acids and Salts; Deoxycholic Acid; Female; Glycochenodeoxycholic Acid; Glycocholic Acid; Graft Rejection; Humans; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity; Taurochenodeoxycholic Acid; Taurocholic Acid | 1994 |
156 other study(ies) available for taurocholic acid and taurochenodeoxycholic acid
| Article | Year |
|---|---|
Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Carrier Proteins; Cloning, Molecular; DNA; Female; Gene Library; Liver; Molecular Sequence Data; Molecular Weight; Oocytes; Organic Anion Transporters, Sodium-Dependent; Protein Conformation; Rats; Restriction Mapping; RNA, Messenger; Sodium; Symporters; Taurocholic Acid; Xenopus laevis | 1991 |
Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Base Sequence; Carrier Proteins; Chromosomes, Human, Pair 12; Cloning, Molecular; DNA Probes; DNA, Complementary; Glycocholic Acid; Humans; Liver; Molecular Sequence Data; Oocytes; Rats; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurodeoxycholic Acid; Xenopus laevis | 1995 |
Bile acid inhibition of P-glycoprotein-mediated transport in multidrug-resistant cells and rat liver canalicular membrane vesicles.
Topics: Animals; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Carcinoma, Hepatocellular; Carrier Proteins; Cell Membrane; Daunorubicin; Depression, Chemical; Doxorubicin; Drug Resistance; Liver Neoplasms; Male; Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Rhodamine 123; Rhodamines; Tumor Cells, Cultured | 1994 |
Functional characterization of the basolateral rat liver organic anion transporting polypeptide.
Topics: Animals; Anion Transport Proteins; Bile Acids and Salts; Carrier Proteins; Female; In Vitro Techniques; Indocyanine Green; Ion Transport; Liver; Oocytes; Rats; Sulfobromophthalein; Xenopus laevis | 1994 |
Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Chromosome Mapping; Cloning, Molecular; Humans; Liver; Molecular Sequence Data; Organic Anion Transporters, Sodium-Dependent; Symporters; Xenopus laevis | 1994 |
Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
Topics: Amino Acid Sequence; Animals; Anions; Base Sequence; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cations, Monovalent; CHO Cells; Cloning, Molecular; COS Cells; Cricetinae; DNA, Complementary; Humans; Ileum; Kidney; Kinetics; Molecular Sequence Data; Organic Anion Transporters, Sodium-Dependent; Recombinant Proteins; RNA, Messenger; Sodium; Symporters; Taurocholic Acid; Transcription, Genetic; Transfection | 1998 |
Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells.
Topics: Animals; Carrier Proteins; CHO Cells; Cricetinae; Estrone; Liver; Oocytes; Organic Anion Transporters, Sodium-Dependent; Rats; Substrate Specificity; Symporters; Taurocholic Acid; Xenopus laevis | 1998 |
Cloning and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Kidney; Male; Membrane Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Oocytes; Organic Anion Transporters; Rats; Rats, Wistar; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Tissue Distribution; Transfection; Xenopus laevis | 1999 |
Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells.
Topics: Animals; Anion Transport Proteins; Carrier Proteins; CHO Cells; Cholic Acid; Cricetinae; Dehydroepiandrosterone Sulfate; Dipeptides; Estradiol; Estrone; Glycocholic Acid; HeLa Cells; Humans; Kinetics; Liver; Ochratoxins; Ouabain; Piperidines; Rats; Recombinant Proteins; Substrate Specificity; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurocholic Acid; Transfection; Xenopus laevis | 1999 |
Molecular cloning and characterization of the murine bile salt export pump.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line; Cell Membrane; Cholagogues and Choleretics; Cholestasis; Cloning, Molecular; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Rats; Sequence Homology, Amino Acid; Taurocholic Acid; Transfection | 2000 |
Expression, transport properties, and chromosomal location of organic anion transporter subtype 3.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Sequence; Animals; Anion Transport Proteins; Base Sequence; Bile; Carrier Proteins; Chromosomes; COS Cells; Dogs; Humans; Intestines; Kinetics; Male; Mice; Molecular Sequence Data; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Sodium | 2000 |
Characterization of the mouse bile salt export pump overexpressed in the baculovirus system.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Baculoviridae; Biological Transport; Blotting, Southern; Cell Line; DNA, Complementary; Gene Expression; Insecta; Mice; Molecular Sequence Data; Phosphorylation; Precipitin Tests | 2001 |
Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cell Line; Humans; Organic Anion Transporters, Sodium-Dependent; Spodoptera; Symporters; Transfection | 2003 |
The human bile salt export pump: characterization of substrate specificity and identification of inhibitors.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Binding, Competitive; Carrier Proteins; Cloning, Molecular; Cyclosporine; DNA, Complementary; Enzyme Inhibitors; Glyburide; Humans; Rifampin; Substrate Specificity | 2002 |
Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).
Topics: Bile Acids and Salts; Dehydroepiandrosterone Sulfate; Drug Resistance, Multiple; Estradiol; Humans; Kinetics; Multidrug Resistance-Associated Proteins; Recombinant Proteins; Steroids; Substrate Specificity; Transfection | 2003 |
Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.
Topics: Animals; Anions; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cholagogues and Choleretics; HeLa Cells; Humans; Kinetics; Liver; Membrane Transport Proteins; Organic Anion Transporters, Sodium-Dependent; Organic Anion Transporters, Sodium-Independent; Rats; Serum Albumin, Bovine; Substrate Specificity; Sulfobromophthalein; Symporters; Taurocholic Acid; Transfection | 2003 |
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Polarity; Cholagogues and Choleretics; Cricetinae; Fibroblasts; Gene Expression; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Rats; Taurocholic Acid; Transfection; Transport Vesicles; Tritium | 2003 |
Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.
Topics: Adenoviridae; Animals; Bile Acids and Salts; Cell Culture Techniques; DNA, Complementary; Dogs; Hepatocytes; Humans; Kidney; Kinetics; Membrane Glycoproteins; Organic Anion Transporters, Sodium-Dependent; Rats; Sodium; Symporters; Transfection | 2005 |
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
Topics: Animals; Bile Acids and Salts; CHO Cells; Cricetinae; Cricetulus; Drug Design; Drug Evaluation, Preclinical; Hormones; Humans; Ligands; Models, Molecular; Molecular Conformation; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship | 2008 |
Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A).
Topics: Bile Acids and Salts; Cell Line; Cell Survival; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Esophagus; Humans; Hydrophobic and Hydrophilic Interactions; Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins | 2013 |
The age dependence of bile acid metabolism in rats.
Topics: Age Factors; Aging; Animals; Bile Acids and Salts; Glycochenodeoxycholic Acid; Glycocholic Acid; Male; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid | 1977 |
Distinct effects of three bile salts on cholesterol solubilization by oleate-monoolein-bile salt micelles.
Topics: Bile Acids and Salts; Cholesterol; Colloids; Glycerides; Hydrogen-Ion Concentration; Micelles; Oleic Acids; Solubility; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1979 |
Effect of taurine conjugated bile salts with and without lecithin on water and electrolyte transport in the canine gallbladder in vivo.
Topics: Animals; Bile Acids and Salts; Chlorides; Dogs; Electrolytes; Female; Gallbladder; Male; Phosphatidylcholines; Phospholipids; Potassium; Sodium; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Water | 1979 |
Influence of taurocholate, taurochenodeoxycholate, and taurodehydrocholate on sulfobromophthalein transport into bile.
Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cricetinae; Ethers; Male; Mesocricetus; Phospholipids; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurocholic Acid | 1979 |
High performance liquid-chromatographic analysis of individual bile acids: free, glycine- and taurine-conjugated bile acids.
Topics: Bile Acids and Salts; Chromatography, High Pressure Liquid; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid | 1979 |
Choleretic and cholestatic effects of infused bile salts in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Dose-Response Relationship, Drug; Male; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1979 |
Separation of conjugated dihydroxy bile acids by thin-layer chromatography.
Topics: Bile; Chenodeoxycholic Acid; Chromatography, Thin Layer; Deoxycholic Acid; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Microchemistry; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1979 |
Bile acids LIII. Application of reverse-phase high-pressure liquid chromatography to the analysis of conjugated bile acids in bile samples.
Topics: Animals; Bile; Bile Acids and Salts; Chromatography, High Pressure Liquid; Glycocholic Acid; Humans; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1978 |
Effect of diester and diether phosphatidylcholine on intestinal absorption of neutral and acidic sterols.
Topics: Animals; Bile Acids and Salts; Cholesterol; Intestinal Absorption; Male; Phosphatidylcholines; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid | 1978 |
A rapid, sensitive method for accurate analysis of individual bile acids in biological fluids by high performance thin-layer chromatography and densitometry.
Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Thin Layer; Densitometry; Deoxycholic Acid; Duodenum; Evaluation Studies as Topic; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Infant; Intestinal Secretions; Lithocholic Acid; Spectrophotometry, Ultraviolet; Taurochenodeoxycholic Acid; Taurocholic Acid | 1978 |
Alterations of rat intestinal disaccharide absorption by bile or conjugated bile acids.
Topics: Animals; Bile; Bile Acids and Salts; Disaccharides; Germ-Free Life; Ileum; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Maltose; Rats; Sucrose; Taurochenodeoxycholic Acid; Taurocholic Acid | 1978 |
Interaction of bile salts with calcium hydroxyapatite: inhibitors of apatite formation exhibit high-affinity premicellar binding.
Topics: Anions; Bile Acids and Salts; Binding, Competitive; Calcium Phosphates; Durapatite; Glycine; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Hydrogen-Ion Concentration; Hydroxyapatites; Micelles; Phosphates; Taurine; Taurochenodeoxycholic Acid; Taurocholic Acid | 1992 |
Microtubule-independent choleresis and anti-cholestatic action of tauroursodeoxycholate in colchicine-treated rat liver.
Topics: Animals; Aspartate Aminotransferases; Bile; Cholestasis; Colchicine; gamma-Glutamyltransferase; Male; Microtubules; Rats; Rats, Inbred Strains; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1992 |
Bile salt/acid induction of DNA damage in bacterial cells: effect of taurine conjugation.
Topics: Bile Acids and Salts; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Lithocholic Acid; Taurine; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid | 1992 |
Cell volume and bile acid excretion.
Topics: Amino Acids; Animals; Bile Acids and Salts; Cell Size; Insulin; Intercellular Junctions; Liver; Male; Permeability; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid; Water-Electrolyte Balance | 1992 |
Proton magnetic resonance studies of the aggregation of taurine-conjugated bile salts.
Topics: Bile Acids and Salts; Electrochemistry; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Taurine; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1992 |
Effects of bile salt infusion on chlorpromazine-induced cholestasis in the isolated perfused rat liver.
Topics: Animals; Bile; Chlorpromazine; Cholestasis; In Vitro Techniques; Isomerism; Kinetics; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Time Factors | 1992 |
Effect of bile acids on ischemia-reperfusion liver injury.
Topics: Animals; Aspartate Aminotransferases; Bile; Ischemia; Isomerism; L-Lactate Dehydrogenase; Liver Circulation; Male; Perfusion; Rats; Rats, Inbred Strains; Reperfusion Injury; Taurochenodeoxycholic Acid; Taurocholic Acid; Uric Acid; Ursodeoxycholic Acid | 1991 |
Calcium binding by monosulfate esters of taurochenodeoxycholate.
Topics: Bile Acids and Salts; Binding Sites; Calcium; Esterification; Phosphatidylcholines; Sulfates; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1991 |
Regulation of cholesterol 7 alpha-hydroxylase by hepatic 7 alpha-hydroxylated bile acid flux and newly synthesized cholesterol supply.
Topics: Animals; Bile Acids and Salts; Blotting, Western; Catalysis; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Hydroxylation; Male; Mevalonic Acid; Microsomes, Liver; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1991 |
Saturation of hepatic transport of taurocholate in rats in vivo.
Topics: Animals; Bile; Biological Transport; Female; Infusions, Intravenous; Kinetics; Liver; Models, Biological; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1991 |
Compartmental analysis of steady-state taurocholate transport kinetics by isolated rat hepatocytes.
Topics: Animals; Biological Transport; Cell Separation; Homeostasis; Liver; Methods; Models, Biological; Taurochenodeoxycholic Acid; Taurocholic Acid | 1991 |
Hepatic injury induced by bile salts: correlation between biochemical and morphological events.
Topics: Animals; Bile; Bile Acids and Salts; Liver; Male; Necrosis; Proteins; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1990 |
Spontaneous formation of pigmentary precipitates in bile salt-depleted rat bile and its prevention by micelle-forming bile salts.
Topics: Animals; Bile; Bile Acids and Salts; Bile Pigments; Biliary Fistula; Bilirubin; Calcium Chloride; Chemical Precipitation; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1990 |
Estradiol-17 beta-D-glucuronide (E-17G) cholestasis in perfused rat liver: fate of E-17G and choleretic responses to bile salts.
Topics: Animals; Bile; Bile Acids and Salts; Biological Transport; Cholagogues and Choleretics; Cholestasis; Dehydrocholic Acid; Estradiol; Male; Rats; Rats, Inbred Strains; Sucrose; Taurochenodeoxycholic Acid; Taurocholic Acid | 1990 |
Side chain conjugation prevents bacterial 7-dehydroxylation of bile acids.
Topics: Bile Acids and Salts; Eubacterium; Glycine; Glycochenodeoxycholic Acid; Glycocholic Acid; Hydroxysteroid Dehydrogenases; Lithocholic Acid; Oxidoreductases; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Taurine; Taurochenodeoxycholic Acid; Taurocholic Acid | 1990 |
Residence time distributions of solutes in the perfused rat liver using a dispersion model of hepatic elimination: 2. Effect of pharmacological agents, retrograde perfusions, and enzyme inhibition on evans blue, sucrose, water, and taurocholate.
Topics: Animals; Azo Compounds; Buffers; Enzyme Inhibitors; Evans Blue; In Vitro Techniques; Lidocaine; Liver; Male; Models, Biological; Norepinephrine; Perfusion; Propranolol; Rats; Rats, Inbred Strains; Sucrose; Taurochenodeoxycholic Acid; Taurocholic Acid | 1990 |
Permeability of the rat biliary tree to ursodeoxycholic acid.
Topics: Absorption; Animals; Bile; Bile Ducts; Cell Membrane Permeability; Cholic Acid; Cholic Acids; Common Bile Duct; Deoxycholic Acid; Epithelium; Glucose; Kinetics; Liver; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Sucrose; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1989 |
Role of primary and secondary bile acids as feedback inhibitors of bile acid synthesis in the rat in vivo.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bile Acids and Salts; Bile Ducts; Cholic Acids; Chromatography, High Pressure Liquid; Feedback; Male; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1989 |
Uptake of bile acids by perfused rat liver: evidence of a structure-activity relationship.
Topics: Animals; Bile Acids and Salts; Cholic Acid; Cholic Acids; Hydroxylation; Isomerism; Liver; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Taurochenodeoxycholic Acid; Taurocholic Acid | 1989 |
Differential effects of two bile salts on ion transport characteristics of teleost intestine.
Topics: Animals; Chenodeoxycholic Acid; Chlorides; Fishes; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestines; Kinetics; Sodium; Taurochenodeoxycholic Acid; Taurocholic Acid | 1987 |
Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat.
Topics: 5'-Nucleotidase; Albumins; Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Isomerism; L-Lactate Dehydrogenase; Male; Nucleotidases; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Time Factors | 1985 |
Differences in the release of cholesterol from taurocholate versus taurochenodeoxycholate micellar solutions.
Topics: Chenodeoxycholic Acid; Cholesterol; Micelles; Solubility; Solutions; Taurochenodeoxycholic Acid; Taurocholic Acid | 1988 |
Effect of various bile salts on calcium concentration and calcium carbonate saturation of rat bile.
Topics: Animals; Bile; Bile Acids and Salts; Calcium; Calcium Carbonate; Glycocholic Acid; Male; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1988 |
Determinants of biliary secretory pressure: the effects of two different bile acids.
Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Male; Rats; Rats, Inbred Strains; Reference Values; Taurochenodeoxycholic Acid; Taurocholic Acid | 1988 |
Separate transport systems for biliary secretion of sulfated and unsulfated bile acids in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Biological Transport; Histocytochemistry; Lithocholic Acid; Liver; Liver Function Tests; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurolithocholic Acid | 1988 |
Spectrophotometric determination of the critical micellar concentration of bile salts using bilirubin monoglucuronide as a micellar probe. Utility of derivative spectroscopy.
Topics: Bilirubin; Chenodeoxycholic Acid; Micelles; Spectrophotometry; Taurochenodeoxycholic Acid; Taurocholic Acid | 1988 |
Effects of taurine-conjugated bile salts on ionic transport of the rabbit esophageal mucosa.
Topics: Amiloride; Animals; Biological Transport; Chlorides; Electric Conductivity; Esophagus; Male; Membrane Potentials; Mucous Membrane; Ouabain; Rabbits; Sodium; Sucrose; Taurine; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1986 |
Purification and reconstitution of the bile acid transport system from hepatocyte sinusoidal plasma membranes.
Topics: Animals; Bile Acids and Salts; Carrier Proteins; Cell Membrane; Liver; Male; Microscopy, Electron; Molecular Weight; Proteolipids; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1986 |
Differing transport maxima values for taurine-conjugated bile salts in rats and hamsters.
Topics: Animals; Biological Transport; Chenodeoxycholic Acid; Cricetinae; Female; Gallbladder; Kinetics; Mesocricetus; Rats; Rats, Inbred Strains; Species Specificity; Taurochenodeoxycholic Acid; Taurocholic Acid | 1986 |
Sulfated and nonsulfated bile acids in urine of patients with biliary atresia: analysis of bile acids by high-performance liquid chromatography.
Topics: Adult; Aged; Bile Acids and Salts; Bile Ducts; Child; Chromatography, High Pressure Liquid; Female; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Infant; Infant, Newborn; Male; Middle Aged; Taurochenodeoxycholic Acid; Taurocholic Acid | 1986 |
Concentrations of glycine- and taurine-conjugated bile acids in portal and systemic venous serum in man.
Topics: Adult; Aged; Bile; Cholecystectomy; Female; Glycine; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Middle Aged; Portal Vein; Taurine; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1984 |
Glycoursodeoxycholate is as effective as tauroursodeoxycholate in preventing the taurocholate-induced cholestasis in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Drug Evaluation, Preclinical; Rats; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1983 |
Fasting and postprandial serum concentrations of glycine- and taurine-conjugated bile acids in Crohn's disease.
Topics: Adult; Aged; Bile Acids and Salts; Crohn Disease; Fasting; Female; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Male; Middle Aged; Taurochenodeoxycholic Acid; Taurocholic Acid | 1983 |
Effects of four taurine-conjugated bile acids on mucosal uptake and lymphatic absorption of cholesterol in the rat.
Topics: Absorption; Animals; Biological Transport; Cholesterol; Cholesterol Esters; Fasting; Intestinal Mucosa; Intestine, Small; Lymph; Male; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1984 |
Unconjugated, glycine-conjugated, taurine-conjugated bile acid nonsulfates and sulfates in urine of young infants with cholestasis.
Topics: Bile Acids and Salts; Bile Ducts; Cholestasis, Intrahepatic; Chromatography, High Pressure Liquid; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Infant; Infant, Newborn; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1984 |
Bile acids inhibit pepsin activity against a refined substrate.
Topics: Bile Acids and Salts; Dipeptides; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Kinetics; Pepsin A; Substrate Specificity; Taurochenodeoxycholic Acid; Taurocholic Acid | 1980 |
A radioimmunoassay for tauro-beta-muricholic acid suitable for use with isolated rat liver cells.
Topics: Animals; Antibody Specificity; Female; Immune Sera; Liver; Radioimmunoassay; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1983 |
Role of bile salts and trypsin in the pathogenesis of experimental alkaline esophagitis.
Topics: Alkalies; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Esophagus; Gastroesophageal Reflux; Rabbits; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid; Trypsin | 1983 |
Interactions between different bile salts in the biliary excretion of the rat.
Topics: Animals; Bile; Bile Acids and Salts; Male; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurolithocholic Acid; Time Factors | 1983 |
The metabolism of chenodeoxycholic acid to beta-muricholic acid in rat liver.
Topics: Animals; Chenodeoxycholic Acid; Cholesterol, Dietary; Female; In Vitro Techniques; Liver; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1983 |
Tauroursodeoxycholate prevents taurocholate induced cholestasis.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Kinetics; Male; Rats; Rats, Inbred WF; Taurochenodeoxycholic Acid; Taurocholic Acid | 1982 |
Mixed micelle properties and intestinal cholesterol uptake.
Topics: Animals; Bile Acids and Salts; Cholesterol; Dose-Response Relationship, Drug; Glycerides; Intestinal Absorption; Intestine, Small; Male; Micelles; Rats; Rats, Inbred Strains; Solubility; Taurochenodeoxycholic Acid; Taurocholic Acid | 1982 |
Conjugation is rate limiting in hepatic transport of ursodeoxycholate in the rat.
Topics: Animals; Bile Acids and Salts; Biological Transport; Cholic Acids; Chromatography, Thin Layer; Deoxycholic Acid; Liver; Male; Rats; Rats, Inbred Strains; Taurine; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1982 |
Diagnostic value of serum primary bile acids in detecting bile acid malabsorption.
Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Fasting; Female; Food; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Ileum; Malabsorption Syndromes; Male; Middle Aged; Postoperative Complications; Taurochenodeoxycholic Acid; Taurocholic Acid | 1982 |
The effect of portal blood bile salt concentrations on bile salt synthesis in rat liver. Studies with isolated hepatocytes.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Circadian Rhythm; Female; Liver; Portal Vein; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1981 |
Intestinal cholesterol uptake from mixed micelles. In vitro effects of taurocholate, taurochenodeoxycholate and tauroursodeoxycholate.
Topics: Animals; Chenodeoxycholic Acid; Cholesterol; In Vitro Techniques; Jejunum; Male; Micelles; Rats; Solubility; Taurochenodeoxycholic Acid; Taurocholic Acid | 1981 |
Thin-layer chromatographic separation of conjugates of ursodeoxycholic acid from those of litho-, chenodeoxy-, deoxy-, and cholic acids.
Topics: Chenodeoxycholic Acid; Chromatography, Thin Layer; Deoxycholic Acid; Glycine; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Lithocholic Acid; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid; Ursodeoxycholic Acid | 1981 |
Biliary transport maximum of tauroursodeoxycholate is twice as high as that of taurocholate in the rat.
Topics: Animals; Bile; Chenodeoxycholic Acid; Cholagogues and Choleretics; Kinetics; Male; Rats; Rats, Inbred Strains; Taurochenodeoxycholic Acid; Taurocholic Acid | 1981 |
Effects of biliary bile acid composition on biliary cholesterol saturation in gallstone patients treated with chenodeoxycholic acid and/or ursodeoxycholic acid.
Topics: Aged; Anticholesteremic Agents; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Deoxycholic Acid; Drug Therapy, Combination; Female; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Male; Middle Aged; Solubility; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1980 |
In vitro inhibition of platelet aggregation by bile salts.
Topics: Adenosine Diphosphate; Bile Acids and Salts; Blood Platelets; Chenodeoxycholic Acid; Cholic Acids; Collagen; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Hydrogen-Ion Concentration; Platelet Aggregation; Serotonin; Taurochenodeoxycholic Acid; Taurocholic Acid | 1980 |
Regulation of protein secretion into bile: studies in mice with a disrupted mdr2 p-glycoprotein gene.
Topics: Alkaline Phosphatase; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; CD13 Antigens; Cholagogues and Choleretics; Enzyme-Linked Immunosorbent Assay; Genes; Lipid Metabolism; Mice; Mice, Transgenic; Mutation; Phospholipids; Proteins; Taurochenodeoxycholic Acid; Taurocholic Acid | 1995 |
Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids.
Topics: Animals; Antioxidants; Bile Acids and Salts; Cells, Cultured; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Hydrogen Peroxide; Liver; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Functional and ultrastructural features of ethanol/bile salts interaction in the isolated perfused rat liver.
Topics: Animals; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Ethanol; L-Lactate Dehydrogenase; Liver; Male; Perfusion; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1995 |
Colchicine inhibits lithocholate-3-O-glucuronide-induced cholestasis in rats.
Topics: Animals; Bile; Cholestasis; Colchicine; Glucuronates; Lithocholic Acid; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid; Vinblastine | 1995 |
Model bile and bile salts accelerate mucin secretion by cultured dog gallbladder epithelial cells.
Topics: Animals; Bile; Bile Acids and Salts; Cell Survival; Cells, Cultured; Cholesterol; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Epithelium; Gallbladder; Mucins; Phospholipids; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1995 |
Hepatic uptake and intestinal absorption of bile acids in the rabbit.
Topics: Animals; Bile Acids and Salts; Intestinal Absorption; Liver; Male; Rabbits; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1994 |
Tubulovesicular transport of horseradish peroxidase in isolated rat hepatocyte couplets: effects of low temperature, cytochalasin B and bile acids.
Topics: Animals; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Cells, Cultured; Cytochalasin B; Cytoplasmic Granules; Histocytochemistry; Horseradish Peroxidase; Liver; Male; Microscopy, Electron; Microtubules; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid; Temperature; Ursodeoxycholic Acid | 1994 |
The mutant Eisai hyperbilirubinemic rat is resistant to bile acid-induced cholestasis and cytotoxicity.
Topics: Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Cholestasis; Horseradish Peroxidase; Hyperbilirubinemia; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Phospholipids; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1994 |
Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Chromatography, High Pressure Liquid; Lipid Metabolism; Liver; Male; Rats; Rats, Wistar; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1994 |
Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in the rat ileum: effects of bile acids and lovastatin.
Topics: Acyl Coenzyme A; Animals; Bile Acids and Salts; Cholesterol; Cholesterol Esters; Diet; Ileum; Intestinal Mucosa; Jejunum; Lovastatin; Male; Microsomes; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1994 |
High concentrations of conjugated bile acids inhibit bacterial growth of Clostridium perfringens and induce its extracellular cholylglycine hydrolase.
Topics: Amidohydrolases; Clostridium perfringens; Feces; Glycochenodeoxycholic Acid; Humans; Taurochenodeoxycholic Acid; Taurocholic Acid | 1994 |
Changes in bile acid composition of serum and gallbladder bile in bile duct ligated dogs.
Topics: Animals; Bile Acids and Salts; Bile Ducts; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Dogs; Gallbladder; Lithocholic Acid; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Time Factors | 1994 |
Tauro alpha-muricholate is as effective as tauro beta-muricholate and tauroursodeoxycholate in preventing taurochenodeoxycholate-induced liver damage in the rat.
Topics: Albumins; Animals; Bile; Cholestasis; Isomerism; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid | 1994 |
Effects of dibutyryl cyclic AMP and papaverine on intrahepatocytic bile acid transport. Role of vesicle transport.
Topics: Animals; Bile Acids and Salts; Biological Transport; Bucladesine; Cells, Cultured; Liver; Male; Papaverine; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1993 |
Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis.
Topics: Acetylglucosaminidase; Animals; Bile; Biomarkers; Calcium; Cells, Cultured; Cholestasis; Cytosol; Exocytosis; Extracellular Space; Horseradish Peroxidase; Kinetics; Liver; Lysosomes; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Reference Values; Taurochenodeoxycholic Acid; Taurocholic Acid; Vasopressins | 1993 |
Selective composition of biliary phosphatidylcholines is affected by secretion rate but not by bile acid hydrophobicity.
Topics: Animals; Bile; Bile Acids and Salts; Chemical Phenomena; Chemistry, Physical; Ileum; Liver; Male; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1993 |
Tauro alpha-muricholate has a biliary transport maximum (Tm) value equivalent to that for tauroursodeoxycholate and tauro beta-muricholate in the rat.
Topics: Animals; Bile; Biliary Tract; Biological Transport; Male; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid | 1994 |
Tauroursodeoxycholate and tauro-beta-muricholate exert cytoprotection by reducing intrahepatocyte taurochenodeoxycholate content.
Topics: Animals; Bucladesine; Cells, Cultured; Intracellular Membranes; L-Lactate Dehydrogenase; Liver; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid | 1993 |
Effects of bile salts on rat hepatic acyl CoA:cholesterol acyltransferase.
Topics: Animals; Bile Acids and Salts; Cholesterol Esters; Cholesterol, VLDL; Esterification; Homeostasis; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lipoproteins, VLDL; Liver; Male; Microsomes, Liver; Perfusion; Rats; Rats, Sprague-Dawley; Sterol O-Acyltransferase; Taurochenodeoxycholic Acid; Taurocholic Acid | 1995 |
Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes.
Topics: Animals; Cell Membrane; Cells, Cultured; Cholagogues and Choleretics; Cytosol; Diglycerides; Enzyme Activation; Exocytosis; Isoenzymes; Liver; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1996 |
Species differences in hepatic bile acid uptake: comparative evaluation of taurocholate and tauroursodeoxycholate extraction in rat and rabbit.
Topics: Animals; Bile Acids and Salts; In Vitro Techniques; Liver; Male; Organ Size; Perfusion; Portal Vein; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Taurochenodeoxycholic Acid; Taurocholic Acid | 1996 |
Mechanism of bile salt-induced mucin secretion by cultured dog gallbladder epithelial cells.
Topics: Acetylglucosamine; Animals; Bile Acids and Salts; Calcimycin; Cells, Cultured; Cyclic AMP; Dinoprostone; Dogs; Edetic Acid; Enzyme Activation; Epithelium; Gallbladder; Ionomycin; Kinetics; Mucins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate; Tritium | 1996 |
Adsorption of mixtures of bile salt taurine conjugates to lecithin-cholesterol membranes: implications for bile salt toxicity and cytoprotection.
Topics: Adsorption; Cholesterol; Membrane Lipids; Membranes, Artificial; Micelles; Phosphatidylcholines; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1996 |
Rat hepatoma L35 cells, a liver-differentiated cell line, display resistance to bile acid repression of cholesterol 7 alpha-hydroxylase.
Topics: Animals; Bile Acids and Salts; Cell Size; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cholic Acids; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 7; Detergents; Dexamethasone; Enzyme Repression; Insulin; Liver; Protein Kinase C; Rats; RNA, Messenger; Sodium Dodecyl Sulfate; Steroid Hydroxylases; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Hepatocellular protein kinase C activation by bile acids: implications for regulation of cholesterol 7 alpha-hydroxylase.
Topics: Animals; Cells, Cultured; Cholesterol 7-alpha-Hydroxylase; Enzyme Activation; Isoenzymes; Liver; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Taurochenodeoxycholic Acid; Taurocholic Acid | 1996 |
Effects of bile salt hydrophobicity on crystallization of cholesterol in model bile.
Topics: Bile Acids and Salts; Cholelithiasis; Cholesterol; Crystallization; Humans; In Vitro Techniques; Models, Biological; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1996 |
Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion.
Topics: Adenosine Triphosphate; Animals; Bile; Biological Transport; Cell Membrane; Cholestasis; Lipopolysaccharides; Liver; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Sepsis-associated cholestasis.
Topics: Adenosine Triphosphate; Bile; Biological Transport; Cell Membrane; Cholestasis; Humans; Sepsis; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Expression of the rat liver Na+/taurocholate cotransporter is regulated in vivo by retention of biliary constituents but not their depletion.
Topics: Animals; Biliary Fistula; Carrier Proteins; Cholestasis; Down-Regulation; Male; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Symporters; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Use of 1H NMR spectroscopy (T2 relaxation times) to examine the effects of conjugated ursodeoxycholic acid on phospholipid fluidity of human gallbladder bile.
Topics: Bile; Bile Acids and Salts; Cholecystectomy; Gallbladder; Glycochenodeoxycholic Acid; Glycodeoxycholic Acid; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Micelles; Phospholipids; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 1997 |
Effect of tauro-alpha-muricholate and tauro-beta-muricholate on oestradiol-17 beta-glucuronide-induced cholestasis in rats.
Topics: Animals; Cholestasis; Estradiol; Isomerism; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Structural mechanisms of bile salt-induced growth of small unilamellar cholesterol-lecithin vesicles.
Topics: Bile Acids and Salts; Cholesterol; Lipids; Micelles; Nephelometry and Turbidimetry; Phosphatidylcholines; Structure-Activity Relationship; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Membrane cholesterol content of cholesterol/phospholipid vesicles determines the susceptibility to both damage and protection by bile salts: implications for bile physiology.
Topics: Bile; Bile Acids and Salts; Cholesterol; Membranes, Artificial; Models, Biological; Phospholipids; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Ultracentrifugation | 1997 |
Role of bile salts in colchicine-induced hepatotoxicity. Implications for hepatocellular integrity and function.
Topics: Alkaline Phosphatase; Animals; Bile Acids and Salts; Chromatography, High Pressure Liquid; Colchicine; Dose-Response Relationship, Drug; Gout Suppressants; Isomerism; L-Lactate Dehydrogenase; Liver; Lumicolchicines; Male; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; Indoles; Isomerism; Isoproterenol; Kinetics; Liver; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate | 1997 |
Activation of protein kinase C alpha and delta by bile acids: correlation with bile acid structure and diacylglycerol formation.
Topics: Animals; Baculoviridae; Bile Acids and Salts; Cells, Cultured; Diacylglycerol Kinase; Diglycerides; Enzyme Activation; Isoenzymes; Liposomes; Liver; Phospholipids; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Rats; Recombinant Proteins; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1997 |
Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid-induced cholestasis in the rat.
Topics: Alkaline Phosphatase; Animals; Calcium; Cholagogues and Choleretics; Cholestasis; Injections, Intravenous; L-Lactate Dehydrogenase; Liver; Phospholipids; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1998 |
Black bear (Ursus americanus) bile composition: seasonal changes.
Topics: Animals; Bile; Bile Acids and Salts; Calcium; Cholesterol; Copper; Gallbladder; Hibernation; Iron; Magnesium; Metals; Phospholipids; Potassium; Seasons; Sodium; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursidae; Zinc | 1997 |
Comparative analysis of conjugated bile acids in human serum using high-performance liquid chromatography and capillary electrophoresis.
Topics: Bile Acids and Salts; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Glycochenodeoxycholic Acid; Glycocholic Acid; Humans; Hydrogen-Ion Concentration; Liver Diseases; Micelles; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Taurochenodeoxycholic Acid; Taurocholic Acid | 1997 |
Effect of high concentrations of bile acids on cultured hepatocytes.
Topics: Alanine Transaminase; Animals; Bile Acids and Salts; Cells, Cultured; Cholagogues and Choleretics; DNA; Dose-Response Relationship, Drug; Glucose; Glycochenodeoxycholic Acid; Glycocholic Acid; Hepatic Encephalopathy; Liver; Male; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid; Urea | 1998 |
Taurocholate transport by brush border membrane vesicles from different regions of chicken intestine.
Topics: Animals; Biological Transport, Active; Chickens; Cholagogues and Choleretics; Glucose; Intestinal Mucosa; Intestines; Membrane Proteins; Microvilli; Phosphoric Monoester Hydrolases; Sodium; Sucrase; Taurochenodeoxycholic Acid; Taurocholic Acid; Time Factors | 1998 |
Bile salts stimulate mucin secretion by cultured dog gallbladder epithelial cells independent of their detergent effect.
Topics: Animals; beta-Cyclodextrins; Bile Acids and Salts; Cells, Cultured; Cholesterol; Cyclodextrins; Detergents; Dogs; Gallbladder; Glycoproteins; Membrane Fluidity; Mucins; Octoxynol; Polysorbates; Taurochenodeoxycholic Acid; Taurocholic Acid | 1998 |
Partial characterization of mechanisms of cytoprotective action of hydrophilic bile salts against hydrophobic bile salts in rats: relation to canalicular membrane fluidity and packing density.
Topics: Animals; Bile Acids and Salts; In Vitro Techniques; Liver; Male; Membrane Fluidity; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1999 |
Evidence for an anion exchange mechanism for uptake of conjugated bile acid from the rat jejunum.
Topics: Absorption; Animals; Anions; Bile Acids and Salts; Biological Transport; Intestinal Mucosa; Ion Transport; Jejunum; Kinetics; Male; Microvilli; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid | 1999 |
Steroid metabolism along the gastrointestinal tract of the cannulated pig.
Topics: Animals; Bacteria; Bile Acids and Salts; Catheterization; Cecum; Cellulose; Cholestanol; Cholesterol; Colon; Dietary Fiber; Disease Models, Animal; Feces; Galactans; Gastrointestinal Contents; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Ileum; Intestinal Mucosa; Intestines; Male; Mannans; Plant Gums; Steroids; Sterols; Swine; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid | 1999 |
Effect of bile salts on oviposition in vitro by Schistosoma mansoni.
Topics: Animals; Bile Acids and Salts; Culture Media; Female; Mice; Oviposition; Parasite Egg Count; Schistosoma mansoni; Taurochenodeoxycholic Acid; Taurocholic Acid | 1999 |
Cholesterol enhances membrane-damaging properties of model bile by increasing the intervesicular-intermixed micellar concentration of hydrophobic bile salts.
Topics: Bile; Bile Acids and Salts; Cholesterol; Drug Combinations; Erythrocyte Membrane; Humans; Micelles; Osmolar Concentration; Phosphatidylcholines; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 1999 |
Bile salt independent flow during bile salt-induced choleresis and cholestasis in the rat: role of biliary thiol secretion.
Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts, Intrahepatic; Cholestasis; Glutathione; Male; Perfusion; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurolithocholic Acid | 2000 |
Differences in Ca(2+) signaling underlie age-specific effects of secretagogues on colonic Cl(-) transport.
Topics: Aging; Animals; Biological Transport; Calcimycin; Calcium; Calcium Signaling; Cells, Cultured; Chlorides; Cholagogues and Choleretics; Colon; GTP-Binding Proteins; Intracellular Membranes; Ionophores; Neurotensin; Rabbits; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Type C Phospholipases | 2001 |
Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Baculoviridae; Bile Acids and Salts; Bile Canaliculi; Biological Transport, Active; Carrier Proteins; Cytoplasmic Vesicles; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurolithocholic Acid; Tritium | 2001 |
Studies of the hepatic excretory defects in essential fatty acid deficiency. Their possible relationship to the genesis of cholesterol gallstones.
Topics: Animals; Bile Ducts; Cholesterol; Cricetinae; Dietary Fats; Erythritol; Fatty Acids, Essential; Gallstones; Liver; Male; Taurochenodeoxycholic Acid; Taurocholic Acid | 1974 |
Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats.
Topics: Animals; Cells, Cultured; Cholagogues and Choleretics; Enzyme Activation; Enzyme Inhibitors; Hepatocytes; Imidazoles; Liver; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Osmolar Concentration; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid | 2001 |
Indirect evidence that intestinal bile salt absorption in rats and hamsters is under positive feedback control.
Topics: Animals; Bile Acids and Salts; Cricetinae; Enterohepatic Circulation; Feedback; Female; Intestinal Absorption; Male; Mesocricetus; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 2001 |
Effects of hydrophobic and hydrophilic bile salt mixtures on cholesterol crystallization in model biles.
Topics: Bile Acids and Salts; Cholelithiasis; Cholesterol; Crystallization; Hydrophobic and Hydrophilic Interactions; Micelles; Phosphatidylcholines; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 2002 |
Cholesterol crystallite nucleation in supersaturated model biles from a thermodynamic standpoint.
Topics: Bile; Calcium; Catalysis; Cations, Divalent; Chemical Precipitation; Cholesterol; Crystallization; Models, Theoretical; Phosphatidylcholines; Solutions; Taurochenodeoxycholic Acid; Taurocholic Acid; Thermodynamics; Time Factors | 2002 |
Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion.
Topics: Animals; Apoptosis; Bile Acids and Salts; Bile Ducts; Cell Division; Cell Line, Transformed; Chemokine CCL2; Cytokines; Epithelial Cells; Interleukin-6; Mice; Mice, Transgenic; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid | 2003 |
Lack of biliary lipid excretion in the little skate, Raja erinacea, indicates the absence of functional Mdr2, Abcg5, and Abcg8 transporters.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Carrier Proteins; Cholagogues and Choleretics; Cholestanols; Coloring Agents; Erythrocytes; Humans; Indocyanine Green; Lipid Metabolism; Lipoproteins; Liver; Male; Mice; Mice, Inbred Strains; Perfusion; Skates, Fish; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurocholic Acid | 2004 |
Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes.
Topics: Animals; Apoptosis; Bile Acids and Salts; Bile Ducts; Blotting, Western; Carbon Radioisotopes; Carrier Proteins; Caspase 9; Caspases; DNA Primers; Dose-Response Relationship, Drug; Epithelium; Flow Cytometry; Glycochenodeoxycholic Acid; Mice; Mice, Inbred BALB C; Multidrug Resistance-Associated Proteins; Organic Anion Transporters, Sodium-Dependent; Phosphatidylcholines; Reverse Transcriptase Polymerase Chain Reaction; Symporters; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 2003 |
Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells: comparison of different modes of evaluating DeltaPsim.
Topics: Animals; Bile Acids and Salts; Bombesin; Bucladesine; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cholecystokinin; Enzyme Inhibitors; Intracellular Membranes; Membrane Potentials; Mice; Mitochondria; Pancreas; Rhodamines; Sincalide; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid; Taurolithocholic Acid; Thapsigargin; Uncoupling Agents | 2004 |
Effects of colchicine on the maximum biliary excretion of cholephilic compounds in rats.
Topics: Analysis of Variance; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Bile Acids and Salts; Colchicine; Erythromycin; Indocyanine Green; Male; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurolithocholic Acid | 2004 |
Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; ATP-Binding Cassette Transporters; Cephalosporins; Common Bile Duct; Imidazoles; Male; Olmesartan Medoxomil; Phenothiazines; Pravastatin; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetrazoles; Vinblastine | 2005 |
The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Bile; Bile Acids and Salts; Biological Transport; Cholesterol; Diosgenin; Lipoproteins; Liver; Mice; Mice, Inbred C57BL; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 2006 |
Single-step analysis of individual conjugated bile acids in human bile using 1H NMR spectroscopy.
Topics: Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Models, Biological; Nuclear Magnetic Resonance, Biomolecular; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 2006 |
[Evaluation on hepatotoxicity caused by Dioscorea bulbifera based on analysis of bile acids].
Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholic Acid; Chromatography, High Pressure Liquid; Dioscorea; Drugs, Chinese Herbal; Heterocyclic Compounds, 4 or More Rings; Least-Squares Analysis; Male; Mice; Mice, Inbred ICR; Plants, Medicinal; Principal Component Analysis; Rhizome; Tandem Mass Spectrometry; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 2011 |
A placental phenotype for intrahepatic cholestasis of pregnancy.
Topics: Cholestasis, Intrahepatic; Female; Humans; Phenotype; Placenta; Pregnancy; Pregnancy Complications; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 2011 |
Short-term feedback regulation of bile salt uptake by bile salts in rodent liver.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Benzophenanthridines; Bile Acids and Salts; Calcineurin Inhibitors; Cholagogues and Choleretics; Down-Regulation; Endocytosis; Feedback, Physiological; Hep G2 Cells; Humans; Liver; Organic Anion Transporters, Sodium-Dependent; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrethrins; Rats; Symporters; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 2012 |
α5 β1-integrins are sensors for tauroursodeoxycholic acid in hepatocytes.
Topics: Allosteric Regulation; Animals; Dimerization; Green Fluorescent Proteins; Hep G2 Cells; Hepatocytes; Humans; Integrin alpha5beta1; Male; MAP Kinase Signaling System; Oligopeptides; Organic Anion Transporters, Sodium-Dependent; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Rats, Wistar; RNA, Small Interfering; Structure-Activity Relationship; Symporters; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid | 2013 |
[The influence of amylin on the bile acid spectrum in rats].
Topics: Animals; Appetite Depressants; Bile; Blood Glucose; Catheterization; Chenodeoxycholic Acid; Common Bile Duct; Deoxycholic Acid; Glycocholic Acid; Hepatocytes; Hydroxylation; Injections, Subcutaneous; Islet Amyloid Polypeptide; Male; Rats; Taurochenodeoxycholic Acid; Taurocholic Acid | 2014 |
Dysregulated hepatic bile acids collaboratively promote liver carcinogenesis.
Topics: Animals; Bile Acids and Salts; Carcinogenesis; Cell Line; Deoxycholic Acid; Diet, High-Fat; Female; Gastrointestinal Microbiome; Hep G2 Cells; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Pregnancy; Streptozocin; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurolithocholic Acid | 2016 |
Partial external biliary diversion in bile salt export pump deficiency: Association between outcome and mutation.
Topics: Adolescent; ATP Binding Cassette Transporter, Subfamily B, Member 11; Bile Acids and Salts; Biliary Tract Surgical Procedures; Biological Transport; Biopsy; Cholestasis, Intrahepatic; Chromatography, High Pressure Liquid; Female; HEK293 Cells; Humans; Infant; Liver; Liver Transplantation; Male; Mutagenesis; Mutation, Missense; Recombinant Proteins; Sequence Analysis, DNA; Substrate Specificity; Tandem Mass Spectrometry; Taurochenodeoxycholic Acid; Taurocholic Acid; Transfection; Treatment Outcome | 2017 |
Dynamic Metabolomics Study of the Bile Acid Pathway During Perioperative Primary Hepatic Carcinoma Following Liver Transplantation.
Topics: Adult; Bile Acids and Salts; Biomarkers; Carcinoma, Hepatocellular; Chenodeoxycholic Acid; Chromatography, Liquid; Female; Glycocholic Acid; Graft Survival; Humans; Liver; Liver Neoplasms; Liver Transplantation; Male; Metabolomics; Middle Aged; Tandem Mass Spectrometry; Taurochenodeoxycholic Acid; Taurocholic Acid; Treatment Outcome | 2020 |
Short communication: Chemical structure, concentration, and pH are key factors influencing antimicrobial activity of conjugated bile acids against lactobacilli.
Topics: Animals; Anti-Infective Agents; Bile Acids and Salts; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Hydrogen-Ion Concentration; Lactobacillus; Probiotics; Taurochenodeoxycholic Acid; Taurocholic Acid; Taurodeoxycholic Acid | 2021 |
Profiling of bile acids and activated receptor S1PR2 in gingival tissues of periodontitis patients.
Topics: Bile Acids and Salts; Humans; Periodontitis; Sphingosine-1-Phosphate Receptors; Taurochenodeoxycholic Acid; Taurocholic Acid | 2023 |