Compounds > taurocholic acid
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taurocholic acid and cyclosporine

taurocholic acid has been researched along with cyclosporine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (28.21)18.2507
2000's14 (35.90)29.6817
2010's13 (33.33)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Craddock, AL; Daniel, RW; Dawson, PA; Kirby, LC; Love, MW; Walters, HC; Wong, MH1
Eckhardt, U; Hagenbuch, B; Hofmann, AF; Meier, PJ; Schroeder, A; Schteingart, CD; Stieger, B; Tynes, R1
Cvetkovic, M; Kim, RB; Leake, B; Nadeau, J; Roden, MM; Walubo, A; Wilkinson, GR1
Hargrove, P; Kim, RB; Lan, LB; Lecureur, V; Schuetz, EG; Schuetz, JD; Sun, D1
Hagenbuch, B; Meier, PJ; Noe, J; St-Pierre, MV1
Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H1
Byrne, JA; Higgins, CF; Linton, KJ; Mieli-Vergani, G; Strautnieks, SS; Thompson, RJ1
Belinsky, MG; Chen, ZS; Hopper-Borge, E; Kotova, E; Kruh, GD; Shchaveleva, I1
Nezu, J; Nozawa, T; Sai, Y; Tamai, I; Tsuji, A1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Caritis, SN; Dorko, K; Ellis, EC; Gramignoli, R; Hansel, M; Hines, RN; Mattison, DR; Sharma, S; Strom, SC; Tahan, V; Venkataramanan, R1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Azer, SA; Stacey, NH2
Berndt, N; Kaplowitz, N; Runnegar, M1
Böhme, M; Gorgas, K; Herfarth, C; Ishikawa, T; Kadmon, M; Keppler, D; Klünemann, C; Otto, G1
Böhme, M; Büchler, M; Jedlitschky, G; Keppler, D; Leier, I1
Böhme, M; Jedlitschky, G; Keppler, D; Leier, I; Müller, M1
Bakatselou, V; Dressman, JB; Mithani, SD; TenHoor, CN1
Bernard, B; Bouvier, E; Cabrol, A; Cadranel, JF; Dorent, R; Gandjbakhch, I; Gerhardt, M; Ghoussoub, JJ; Lunel, F; Myara, A; Opolon, P; Trivin, F1
Fattinger, K; Kullak-Ublick, GA; Madon, J; Meier, PJ; Stieger, B1
Elamiri, A; Perwaiz, S; Tuchweber, B; Yousef, IM1
Cui, Y; Faulstich, H; Fehrenbach, T; Keppler, D1
Akita, H; Hayashi, H; Hofmann, AF; Mita, S; Onuki, R; Sugiyama, Y; Suzuki, H1
Gäbel, G; Honscha, KU; Honscha, W; Kneuer, C1
Narushima, K; Suzuki, H; Takada, T; Yamanashi, Y1
Choi, MK; Han, YH; Kim, H; Shim, CK; Song, IS1
Brouwer, KL; Generaux, GT; Polli, JW; Vora, S; Webster, LO; Wolf, KK1
Murray, JW; Thosani, AJ; Wang, P; Wolkoff, AW1
Armstrong, C; Colombo, F; Duan, J; Rioux, N1
Baranyai, Z; Jakab, F; Jemnitz, K; Szabo, M; Vereczkey, L; Veres, Z1
Du, C; Guan, H; Li, L; Li, P; Liu, C; Liu, M; Tong, S; Wang, C; Zhang, Z1
Baranyai, Z; Jakab, F; Jemnitz, K; Szabo, M; Veres, Z1
Al-Attrache, H; Azzi, PB; Guguen-Guillouzo, C; Guillouzo, A; Humbert, L; Rainteau, D; Savary, CC; Sharanek, A1
Blanco-Prieto, MJ; Dios-Viéitez, Mdel C; Guada, M; Lana, H; Lasa-Saracíbar, B1
Hsiao, JK; Huang, YY; Wu, MR1

Reviews

1 review(s) available for taurocholic acid and cyclosporine

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010

Other Studies

38 other study(ies) available for taurocholic acid and cyclosporine

ArticleYear
Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Amino Acid Sequence; Animals; Anions; Base Sequence; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cations, Monovalent; CHO Cells; Cloning, Molecular; COS Cells; Cricetinae; DNA, Complementary; Humans; Ileum; Kidney; Kinetics; Molecular Sequence Data; Organic Anion Transporters, Sodium-Dependent; Recombinant Proteins; RNA, Messenger; Sodium; Symporters; Taurocholic Acid; Transcription, Genetic; Transfection

1998
Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Animals; Carrier Proteins; CHO Cells; Cricetinae; Estrone; Liver; Oocytes; Organic Anion Transporters, Sodium-Dependent; Rats; Substrate Specificity; Symporters; Taurocholic Acid; Xenopus laevis

1998
Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Bile Acids and Salts; Biological Transport, Active; Carrier Proteins; Cells, Cultured; HeLa Cells; Humans; Kinetics; Liver; Nicotine; Organic Anion Transporters, Sodium-Dependent; Plasmids; RNA, Messenger; Salicylates; Symporters; Vaccinia virus; Valproic Acid

1999
Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein.
    Molecular pharmacology, 2000, Volume: 57, Issue:1

    Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Humans; Karyotyping; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Sequence Homology, Amino Acid

2000
Characterization of the mouse bile salt export pump overexpressed in the baculovirus system.
    Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:5

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Baculoviridae; Biological Transport; Blotting, Southern; Cell Line; DNA, Complementary; Gene Expression; Insecta; Mice; Molecular Sequence Data; Phosphorylation; Precipitin Tests

2001
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.
    Cancer research, 2001, Oct-01, Volume: 61, Issue:19

    Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium

2001
The human bile salt export pump: characterization of substrate specificity and identification of inhibitors.
    Gastroenterology, 2002, Volume: 123, Issue:5

    Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Binding, Competitive; Carrier Proteins; Cloning, Molecular; Cyclosporine; DNA, Complementary; Enzyme Inhibitors; Glyburide; Humans; Rifampin; Substrate Specificity

2002
Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).
    Molecular pharmacology, 2003, Volume: 63, Issue:2

    Topics: Biological Transport; Cells, Cultured; Cyclosporine; Estradiol; Glycocholic Acid; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Multidrug Resistance-Associated Proteins; Osmotic Pressure; Propionates; Quinolines; Recombinant Proteins; Transfection

2003
Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:7

    Topics: Animals; Anions; Bile; Biological Transport; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Estrone; Hepatocytes; In Vitro Techniques; Injections, Intravenous; Liver-Specific Organic Anion Transporter 1; Oocytes; Peptides; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Xenopus laevis

2003
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:2

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Adult; Age Factors; Aged; Biological Transport; Cells, Cultured; Cold Temperature; Cyclosporine; Female; Gestational Age; Hepatocytes; Humans; Hydroxyprogesterones; Kinetics; Male; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Protein 2; Rifampin; RNA, Messenger; Taurocholic Acid; Verapamil; Young Adult

2013
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
Effect of cyclosporin A in vivo on taurocholate uptake by rat hepatocytes.
    Biochemical pharmacology, 1991, Oct-24, Volume: 42, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubin; Cyclosporine; Liver; Male; Rats; Rats, Inbred Strains; Taurocholic Acid

1991
Microcystin uptake and inhibition of protein phosphatases: effects of chemoprotectants and self-inhibition in relation to known hepatic transporters.
    Toxicology and applied pharmacology, 1995, Volume: 134, Issue:2

    Topics: Animals; Biological Transport; Cyclosporine; Enzyme Inhibitors; Liver; Male; Marine Toxins; Mice; Microcystins; Oxazoles; Peptides, Cyclic; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Taurocholic Acid

1995
Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile.
    Gastroenterology, 1993, Volume: 104, Issue:5

    Topics: Adenosine Triphosphate; Adult; Bile; Biological Transport; Cell Membrane; Cyclosporine; Humans; Leukotrienes; Liver; Middle Aged; SRS-A; Tacrolimus; Taurocholic Acid

1993
ATP-dependent export pumps and their inhibition by cyclosporins.
    Advances in enzyme regulation, 1994, Volume: 34

    Topics: Adenosine Triphosphate; Animals; Bile; Bile Canaliculi; Biological Transport, Active; Carrier Proteins; Cell Membrane; Cyclosporine; Cyclosporins; Daunorubicin; Drug Resistance, Multiple; Immunosuppression Therapy; Leukotriene C4; Male; Rats; Rats, Wistar; Taurocholic Acid

1994
Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver.
    Gastroenterology, 1994, Volume: 107, Issue:1

    Topics: Adenosine Triphosphate; Animals; Bile Acids and Salts; Bile Canaliculi; Biological Transport; Carbon Radioisotopes; Cell Membrane; Cholestasis; Cyclosporine; Cyclosporins; In Vitro Techniques; Leukotriene C4; Liver; Male; Rats; Rats, Wistar; Taurocholic Acid; Time Factors

1994
Cyclosporine-induced interference with uptake of bile acids by human hepatocytes.
    Transplantation proceedings, 1993, Volume: 25, Issue:5

    Topics: Bile Acids and Salts; Biological Transport, Active; Cholic Acid; Cholic Acids; Cyclosporine; Glycocholic Acid; Humans; In Vitro Techniques; Kinetics; Liver; Taurocholic Acid

1993
Estimation of the increase in solubility of drugs as a function of bile salt concentration.
    Pharmaceutical research, 1996, Volume: 13, Issue:1

    Topics: Bile Acids and Salts; Chemical Phenomena; Chemistry, Physical; Cholagogues and Choleretics; Cyclosporine; Diazepam; Fasting; Food; Griseofulvin; Intestinal Absorption; Models, Chemical; Pentazocine; Phenytoin; Solubility; Steroids; Taurocholic Acid

1996
Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:3

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Cyclosporine; Fasting; Female; Glycocholic Acid; Heart Transplantation; Hepatitis, Chronic; Humans; Immunosuppressive Agents; Lithocholic Acid; Male; Middle Aged; Spectrophotometry, Ultraviolet; Taurocholic Acid; Ursodeoxycholic Acid

1996
Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver.
    Gastroenterology, 2000, Volume: 118, Issue:2

    Topics: Adenosine Triphosphate; Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Carrier Proteins; Cell Line; Cyclosporine; Estradiol; Glyburide; Kinetics; Liver; Rats; Recombinant Proteins; Rifampin; Rifamycins; Spodoptera; Taurocholic Acid; Transfection

2000
Effect of mdr2 mutation with combined tandem disruption of canalicular glycoprotein transporters by cyclosporine A on bile formation in mice.
    Pharmacological research, 2003, Volume: 48, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Bile Acids and Salts; Bile Canaliculi; Carrier Proteins; Cyclosporine; Glycoproteins; Immunosuppressive Agents; Mice; Mice, Knockout; Mutation; Taurocholic Acid

2003
Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:5

    Topics: Alkaloids; Biological Transport; Carrier Proteins; Cell Line; Cyclosporine; Humans; Immunosuppressive Agents; Liver; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters, Sodium-Independent; Phalloidine; Sirolimus; Solute Carrier Organic Anion Transporter Family Member 1B3; Sulfobromophthalein; Tacrolimus; Taurocholic Acid; Time Factors

2003
Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:9

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport; Cholestasis; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoresceins; Kinetics; LLC-PK1 Cells; Organic Anion Transporters, Sodium-Dependent; Oxadiazoles; Rifampin; Rifamycins; Swine; Symporters; Taurocholic Acid; Transfection

2006
Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells.
    Pflugers Archiv : European journal of physiology, 2007, Volume: 454, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Cell Line; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acid; Cyclosporine; Deoxycholic Acid; Dogs; Enzyme Inhibitors; Epithelial Cells; Gastrointestinal Agents; Gene Expression Regulation; Kidney; Paclitaxel; Rhodamine 123; Taurocholic Acid

2007
Niemann-pick C1-like 1 mediates alpha-tocopherol transport.
    Molecular pharmacology, 2008, Volume: 74, Issue:1

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Azetidines; Biological Transport; Caco-2 Cells; Cholesterol; Cyclosporine; Ezetimibe; Humans; Immunohistochemistry; Intestinal Absorption; Male; Membrane Proteins; Membrane Transport Proteins; Micelles; Phosphatidylcholines; Rats; Rats, Wistar; Taurocholic Acid; Temperature; Time Factors; Vitamin A

2008
Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:2

    Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cyclosporine; Dogs; Estradiol; Flow Cytometry; Humans; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; p-Aminohippuric Acid; Penicillin G; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rhodamines; Species Specificity; Substrate Specificity; Taurocholic Acid; Transport Vesicles

2009
Use of cassette dosing in sandwich-cultured rat and human hepatocytes to identify drugs that inhibit bile acid transport.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:1

    Topics: Animals; Anti-Infective Agents; Bile; Bile Acids and Salts; Biological Transport, Active; Cells, Cultured; Cholagogues and Choleretics; Cyclosporine; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Liver; Male; Rats; Rats, Wistar; Taurocholic Acid

2010
Heterogeneous accumulation of fluorescent bile acids in primary rat hepatocytes does not correlate with their homogenous expression of ntcp.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:1

    Topics: Animals; Bile Acids and Salts; Cells, Cultured; Cyclosporine; Enzyme Inhibitors; Fluorescent Dyes; HeLa Cells; Hepatocytes; Humans; Molecular Chaperones; Organic Anion Transporters, Sodium-Dependent; Rats; Single-Cell Analysis; Symporters; Taurocholic Acid

2011
A high throughput in vitro mrp2 assay to predict in vivo biliary excretion.
    Xenobiotica; the fate of foreign compounds in biological systems, 2012, Volume: 42, Issue:2

    Topics: Animals; ATP-Binding Cassette Transporters; Benzbromarone; Bile Canaliculi; Biliary Tract; Biological Transport; Cyclosporine; Digoxin; Drug Evaluation, Preclinical; Drug Interactions; Fluoresceins; High-Throughput Screening Assays; Metabolic Clearance Rate; Propionates; Quinolines; Rats; Taurocholic Acid; Transport Vesicles

2012
Differential inhibitory effect of cyclosporin A and bosentan on taurocholate uptake in human and rat hepatocytes as a function of culturing time.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:1

    Topics: Aged; Animals; Biological Transport; Bosentan; Cells, Cultured; Cyclosporine; Female; Hepatocytes; Humans; Male; Middle Aged; Rats; Rats, Wistar; Sulfonamides; Taurocholic Acid; Time Factors

2012
Effects of taurocholic acid on immunoregulation in mice.
    International immunopharmacology, 2013, Volume: 15, Issue:2

    Topics: CD4-CD8 Ratio; Cell Separation; Cells, Cultured; Cyclosporine; Flow Cytometry; Gene Expression Regulation; Humans; Immune System Diseases; Immunomodulation; Interleukin-1beta; Leukocytes, Mononuclear; Lipopolysaccharides; Medicine, Chinese Traditional; Taurocholic Acid; Tumor Necrosis Factor-alpha

2013
Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict a risk of drug induced hepatotoxicity.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Biological Transport; Bosentan; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Chromans; Cyclosporine; Hepatocytes; Humans; Rats; Sulfobromophthalein; Sulfonamides; Taurocholic Acid; Thiazolidinediones; Troglitazone

2013
Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 141, Issue:1

    Topics: Actins; Cell Line, Tumor; Cell Survival; Cholestasis; Cyclosporine; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Gene Expression; Humans; Immunosuppressive Agents; Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Taurocholic Acid; Time-Lapse Imaging

2014
Lipid nanoparticles enhance the absorption of cyclosporine A through the gastrointestinal barrier: In vitro and in vivo studies.
    International journal of pharmaceutics, 2016, Mar-16, Volume: 500, Issue:1-2

    Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Cyclosporine; Diglycerides; Female; Humans; Immunosuppressive Agents; Intestinal Absorption; Mice, Inbred BALB C; Nanoparticles; Phosphatidylcholines; Poloxamer; Polysorbates; Taurocholic Acid

2016
Role of Sodium Taurocholate Cotransporting Polypeptide as a New Reporter and Drug-Screening Platform: Implications for Preventing Hepatitis B Virus Infections.
    Molecular imaging and biology, 2020, Volume: 22, Issue:2

    Topics: Animals; Cell Line, Tumor; Cyclosporine; Cytoplasm; Female; Fluorescent Dyes; Genes, Reporter; HEK293 Cells; Hepatitis B; Hepatitis B virus; Hepatitis D; Hepatitis Delta Virus; Hepatocytes; Humans; Indocyanine Green; Liver; Mice; Mice, Inbred BALB C; Mice, Nude; Organic Anion Transporters, Sodium-Dependent; Symporters; Taurocholic Acid

2020