taurine has been researched along with tramiprosate in 154 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 71 (46.10) | 18.7374 |
| 1990's | 24 (15.58) | 18.2507 |
| 2000's | 21 (13.64) | 29.6817 |
| 2010's | 29 (18.83) | 24.3611 |
| 2020's | 9 (5.84) | 2.80 |
| Authors | Studies |
|---|---|
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
| Desarmenien, M; Feltz, P; Headley, PM | 1 |
| Carlà, V; Giotti, A; Magnani, M; Sgaragli, GP | 1 |
| Rokyta, R; Safanda, J; Sobotka, P; Záhlava, J | 1 |
| Adembri, G; Bartolini, A; Bartolini, R; Galli, A; Giotti, A; Zilletti, L | 1 |
| Holopainen, I; Rau, C; Wojcik, WJ | 1 |
| Ahtee, L; Mäkinen, M; Panula-Lehto, E | 1 |
| Fernández, A; Ruiz, RM; Serrano, I; Serrano, JS | 1 |
| Castresana, A; Emmanouilidis, E; Payan, C; Poenaru, S; Rouhani, S; Soulairac, A; Tran, G | 1 |
| Dreher, J; Eshel, G; Jackson, DM; Ong, J; Wong, LS | 1 |
| Fernandez, A; Ruiz de Valderas, RM; Serrano, JS; Serrano, MI | 1 |
| Cook, BJ; Cooper, JF; Wagner, RM | 1 |
| Jones, AJ; Keen, P; Ray, NJ | 1 |
| Fincher, AS; Frye, GD; Griffith, WH; Lorenzetti, M; Trzeciakowski, J | 1 |
| Kohlenbach, A; Schlicker, E | 1 |
| Boeckxstaens, GE; Herman, AG; Pelckmans, PA; Rampart, M; Ruytjens, IF; Van Maercke, YM; Verbeuren, TJ | 1 |
| Crema, A; Manzo, L; Onori, L; Perucca, E; Rizzi, CA; Tonini, M | 1 |
| Giuliani, S; Maggi, CA; Manzini, S; Meli, A | 1 |
| Barbier, AJ; Guenaneche, F; Lefebvre, RA | 1 |
| Agmo, A; Paredes, R; Soria, P | 1 |
| Candura, SM; Crema, A; Frigo, GM; Manzo, L; Onori, L; Rizzi, CA; Tonini, M | 1 |
| Candura, SM; Costa, LG; Garlaschelli, L; Manzo, L; Olibet, G; Rizzi, CA; Tonini, M | 1 |
| Ahtee, L; Männistö, PT; Panula-Lehto, E; Tuominen, RK | 1 |
| Harding, RK; Krantis, A | 1 |
| Johnston, GA; Kerr, DI; Ong, J | 1 |
| Hara, S; Morioka, S; Satoh, K; Yanagihara, S | 1 |
| Greentree, SG; Pertwee, RG; Swift, PA | 1 |
| Giuliani, S; Maggi, CA; Meli, A | 1 |
| Handley, SL; Heaton, JC; Rea, PJ; Singh, L | 1 |
| Goodwin, DW; Liskow, BI | 1 |
| Iversen, LL; Wong, EH | 1 |
| Maggi, CA; Meli, A; Santicioli, P | 4 |
| Maggi, CA; Manzini, S; Meli, A | 2 |
| Agmo, A; Giordano, M | 1 |
| Allan, RD; Dickenson, HW | 1 |
| Kannisto, P; Owman, C; Schmidt, G; Walles, B | 1 |
| Allan, AM; Harris, RA | 1 |
| Sawynok, J | 1 |
| Andrés-Trelles, F; Cecchini, BG; Orviz, P | 1 |
| Jenks, BG; Lenssen, FJ; Vaudry, H; Verburg-van Kemenade, BM | 1 |
| Chiarugi, VP; Corradetti, R; Pepeu, G; Ruggiero, M | 1 |
| Anderson, GM; Chakraborty, M; Cohen, DJ; Durkin, TA | 1 |
| Ishizawa, M | 1 |
| Horisaka, K; Masuda, M | 1 |
| Conte, B; Furio, M; Maggi, CA; Meli, A; Santicioli, P | 1 |
| Ong, J | 1 |
| Lombardini, JB | 1 |
| Ahtee, L; Vahala, ML | 1 |
| Meldrum, B | 1 |
| Casida, JE; Cole, LM; Lawrence, LJ | 1 |
| Boismare, F; Chretien, P; Daoust, M; Durlach, J; Lhuintre, JP; Moore, N; Saligaut, C | 1 |
| Cunningham, JR; Neal, MJ | 1 |
| Horisaka, K | 1 |
| Brown, DA; Scholfield, CN | 1 |
| Beani, L; Bianchi, C; Marzola, G; Tanganelli, S | 1 |
| Debeljuk, L; Diaz, MC; Seilicovich, A | 1 |
| Giotti, A; Luzzi, S; Spagnesi, S; Zilletti, L | 2 |
| Lalley, PM | 1 |
| Gallagher, JP; Nakamura, J; Shinnick-Gallagher, P | 1 |
| DeFeudis, FV | 1 |
| Halmekoski, J; Liljequist, R; Paasonen, MK; Solatunturi, E | 1 |
| Fariello, RG; Golden, GT | 1 |
| Karppanen, H; Paakkari, I; Paakkari, P; Paasonen, MK | 1 |
| Ault, B; Nadler, JV | 1 |
| Atkinson, HD; Little, HJ | 1 |
| Black, JA; Fariello, RG; Golden, GT | 1 |
| Marshall, FD; Seely, JE | 1 |
| Neuhoff, V; Schulze, E | 1 |
| Franconi, F; Giotti, A; Manzini, S; Martini, F; Stendardi, I; Zilletti, L | 1 |
| Anwar, N; Mason, DF | 1 |
| Kaplita, PV; Triggle, DJ; Waters, DH | 1 |
| Capek, R; Esplin, B | 1 |
| Halmekoski, J; Karppanen, H; Paakkari, I; Paakkari, P; Paasonen, MK | 1 |
| Fariello, RG; Golden, GT; Pisa, M | 1 |
| Okamoto, K; Sakai, Y | 1 |
| Fariello, RG; Shug, AL | 1 |
| Bloch, R; Bousquet, P; Feldman, J; Schwartz, J | 1 |
| Candura, SM; Coccini, T; Costa, LG; Manzo, L; Tonini, M | 1 |
| Desrues, L; Lamacz, M; Tonon, MC; Vaudry, H | 1 |
| Campagna, F; Carotti, A; Casini, G; Conte-Camerino, D; De Luca, A; Palluotto, F; Pierno, S; Tricarico, D | 1 |
| Campagna, F; Carotti, A; Casini, G; Conte Camerino, DC; De Luca, A; Pierno, S; Tricarico, D | 1 |
| Ahtee, L; Mäkinen, M; Männistö, P; Rosenqvist, K; Tuominen, RK | 1 |
| Krantis, A; MacNaughton, WK; Pineau, BC | 1 |
| Klunk, WE; McClure, RJ; Pettegrew, JW; Xu, CJ | 1 |
| Andrés-Trelles, F; Baamonde, A; Hidalgo, A; Meana, A; Menendez, L; SanMartin, S | 1 |
| Asadi, I; Fernández, A; Serrano, JS; Serrano, MI; Serrano-Martino, MC | 2 |
| Bajenaru, O; Dall'Ava-Santucci, J; Dinh-Xuan, AT; Emmanouilidis, E; Manicom, R; Poenaru, S; Rouhani, S; Tran, G | 1 |
| Glasgow, I; Krantis, A; Mattar, K | 1 |
| Ahtee, L; Majasaari, M; Ruotsalainen, M; Salimäki, J | 1 |
| Bosc, N; Fabre, H; Perrin, C | 1 |
| Antonucci, A; Cavallini, D; Costa, M; Montefoschi, G; Pecci, L | 1 |
| Ozdem, SS; Sadan, G; Taşatargil, A; Usta, C | 1 |
| Baamonde, A; Gutiérrez, M; Hidalgo, A; Menéndez, L; SanMartín, S | 1 |
| Cook, AM; Laue, H | 1 |
| Bowers, RJ; van Gelder, NM | 1 |
| Hodge, CW; Koenig, HN; Nannini, MA; Olive, MF; Ou, CJ | 1 |
| Castel, H; Desrues, L; Malagon, MM; Tonon, MC; Vaudry, H | 1 |
| Ge, YX; Han, YF; Hu, NW; Hu, XD; Li, WM; Liu, XG; Zhang, HM; Zhang, T; Zhou, LJ | 1 |
| Aman, A; Azzi, M; Gervais, F; Kong, X; Krzywkowski, P; Lacombe, D; Laurin, J; Morissette, C; Paquette, J; Szarek, WA; Tremblay, P; Yu, M | 1 |
| Wright, TM | 1 |
| Aisen, PS; Briand, R; Garceau, D; Gervais, F; Laurin, J; Saumier, D; Tremblay, P | 1 |
| Melnikova, I | 1 |
| Avila, J; Hernández, F; Moreno, FJ; Santa-María, I | 1 |
| Cook, AM; Denger, K; Hollemeyer, K; Huhn, T; Kaspar, K; Mayer, J; Smits, TH | 1 |
| Sugimoto, H | 1 |
| Aisen, PS; Duong, A; Ferris, SH; Garceau, D; Gauthier, S; Haine, D; Lau, W; Oh, J; Sampalis, J; Saumier, D; Suhy, J; Vellas, B | 1 |
| Aisen, PS; Duong, A; Ferris, SH; Garceau, D; Gauthier, S; Haine, D; Lau, W; Oh, J; Sampalis, J; Saumier, D; Suhy, J | 1 |
| Cook, AM; Mayer, J | 1 |
| Duong, A; Garceau, D; Haine, D; Sampalis, J; Saumier, D | 1 |
| Swanoski, MT | 1 |
| Aman, AM; de Guzman, JM; Kong, X; Martineau, E; Mayer, PM; Rodionova, L | 1 |
| Matsuoka, N; Mitani, Y; Miyake, A; Nagakura, A; Shitaka, Y | 1 |
| Agwane, SB; Maurya, PK; Rao, RN; Shinde, DD | 1 |
| Meng, F; Raleigh, DP | 1 |
| Martineau, E; Mayer, PM | 1 |
| Khalid, S; Maurya, PK; Rao, RN; Shinde, DD | 1 |
| Caltagirone, C; Ferrannini, L; Marchionni, N; Nappi, G; Scapagnini, G; Trabucchi, M | 1 |
| Ding, H; Tao, L; Tian, H; Wang, S; Wang, Y; Wu, S; Xiang, J; Yue, Y | 1 |
| Ding, K; Wang, P | 1 |
| Cabrera-Ruíz, E; Estrada-Mondragón, A; Martínez-Torres, A; Miledi, R; Reyes-Haro, D | 1 |
| De Nigris, F; Fasano, A; Ricciardi, L; Specchia, A | 1 |
| Adornetto, A; Bagetta, G; Cavaliere, F; Corasaniti, MT; Morrone, LA; Nucci, C; Rusciano, D; Russo, R; Varano, GP | 1 |
| Bongen, P; Brener, O; Demuth, HU; Dunkelmann, T; Funke, SA; Gremer, L; Hoyer, W; Janssen, A; Jürgens, D; Kadish, I; Kutzsche, J; Langen, KJ; Mirecka, EA; Nagel-Steger, L; Oesterhelt, F; Pietruszka, J; Rudolph, S; Tusche, M; van Groen, T; Willbold, D; Willuweit, A | 1 |
| Cacciari, C; Caltagirone, C; Casini, AR; Chiapponi, C; Cravello, L; Fratangeli, C; Gianni, W; Iorio, M; Orfei, MD; Piras, F; Sancesario, G; Spalletta, G | 1 |
| Albanese, G; Mutolo, MG; Pescosolido, N; Rusciano, D | 1 |
| Arosio, P; Chia, S; Cohen, SI; Costa, AR; Dobson, CM; Habchi, J; Joshi, P; Knowles, TP; Linse, S; Müller, MB; Nollen, EA; Perni, M; Vendruscolo, M; Yagi-Utsumi, M | 1 |
| Bittner, T; Blennow, K; Höglund, K; Rozga, M | 1 |
| Blennow, K; Fillit, H; Hey, JA; Kocis, P; Ray, S; Sinko, W; Tolar, M; Yu, J | 1 |
| Angeli, A; Calderone, V; Chiarugi, P; Comito, G; Di Cesare Mannelli, L; Fragai, M; Francesconi, O; Ghelardini, C; Gratteri, P; Gualdani, R; Louka, A; Nativi, C; Nocentini, A; Richichi, B; Supuran, CT; Tadini-Buoninsegni, F | 1 |
| Abushakra, S; Amedio, J; Hey, JA; Kaplan, PL; Kocis, P; Power, A; Tolar, M; Versavel, M; Yu, JY | 1 |
| Chiosi, F; Costagliola, C; Davinelli, S; Di Marco, R; Scapagnini, G | 1 |
| Abushakra, S; Cummings, J; Gauthier, S; Hey, JA; Porsteinsson, A; Power, A; Sadowsky, C; Scheltens, P; Shen, L; Tolar, M; Vellas, B; Wang, P | 1 |
| Liu, Y; Wang, Q; Xu, LP; Yang, B; Zhang, X | 1 |
| Abushakra, S; Hey, JA; Hort, J; Kocis, P; Power, A; Tolar, M; Vyhnálek, M; Yu, JY | 1 |
| Dang, H; Kaufman, DL; Olsen, R; Tian, J; Wallner, M | 1 |
| Agrawal, N; Skelton, AA | 1 |
| Dang, H; Gilles, S; Kaufman, DL; O'Laco, KA; Song, M; Tian, J; Tiu, BC; Zakarian, C | 1 |
| Bagnoli, P; Cammalleri, M; Dal Monte, M; Locri, F; Rusciano, D | 1 |
| Chakravarty, H; Chen, WH; Ju, Y; Tam, KY | 1 |
| Amato, R; Bagnoli, P; Cammalleri, M; Dal Monte, M; Rusciano, D | 1 |
| Ju, Y; Tam, KY | 1 |
| Campagna, G; Capobianco, D; Costagliola, C; Marino, PF; Rossi, GCM | 1 |
| Kaufman, DL; Song, M; Tian, J | 1 |
| Dujardin, A; Himbert, S; Juhasz, J; Rheinstädter, MC; Ros, S; Stöver, HDH; Zou, X | 1 |
| Castellari, M; Terriente-Palacios, C | 1 |
| Banaj, N; Bossù, P; Golesorkhtafti, S; Lembo, M; Messina, B; Sireno, L; Spalletta, G; Toppi, E | 1 |
| Castellari, M; Hortós, M; Peteiro, C; Rubiño, S; Terriente-Palacios, C | 1 |
8 review(s) available for taurine and tramiprosate
| Article | Year |
|---|---|
Pharmacological treatment of alcohol intoxication, withdrawal and dependence: a critical review.
Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Antidepressive Agents, Tricyclic; Bromocriptine; Cyanamide; Disulfiram; Ethanol; Fenfluramine; Humans; Lithium; Nitroimidazoles; Substance Withdrawal Syndrome; Sympathomimetics; Taurine; Tranquilizing Agents; Zimeldine | 1987 |
Involvement of GABA and other inhibitory amino acids in thermoregulation.
Topics: Allylglycine; Amino Acids; Animals; Body Temperature Regulation; Brain; Fever; gamma-Aminobutyric Acid; Hypothermia; Muscimol; Taurine | 1984 |
Tramiprosate.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Humans; Nootropic Agents; Randomized Controlled Trials as Topic; Taurine | 2006 |
[New approaches for the development of anti-Alzheimer's disease drugs based on the cholinergic hypothesis and amyloid hypothesis].
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Choline; Cholinesterase Inhibitors; Drug Design; Enzyme Inhibitors; Humans; Taurine | 2008 |
[Progress in the development of anti-amyloid drugs for treatment of Alzheimer's disease.].
Topics: Alanine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Azepines; Drug Design; Enzyme Inhibitors; Flurbiprofen; Humans; Taurine | 2010 |
The potential protective effect of tramiprosate (homotaurine) against Alzheimer's disease: a review.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Clinical Trials as Topic; Humans; Nootropic Agents; tau Proteins; Taurine | 2012 |
Proteoglycans and glycosaminoglycans in misfolded proteins formation in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Clinical Trials as Topic; Glycosaminoglycans; Heparin, Low-Molecular-Weight; Humans; Inositol; Phosphorylation; Propane; Protein Aggregation, Pathological; Protein Folding; Proteoglycans; Sulfonic Acids; tau Proteins; Taurine | 2014 |
Structure and Function of Alzheimer's Amyloid βeta Proteins from Monomer to Fibrils: A Mini Review.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Antibodies, Monoclonal, Humanized; Clinical Trials as Topic; Humans; Peptide Fragments; Taurine | 2019 |
10 trial(s) available for taurine and tramiprosate
| Article | Year |
|---|---|
Do taurine and its analogs or cogeners have actions in common?
Topics: Amino Acids; Animals; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Female; Humans; Mice; Myocardium; Pregnancy; Taurine | 1981 |
A Phase II study targeting amyloid-beta with 3APS in mild-to-moderate Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Brain; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Down-Regulation; Female; GABA Agonists; Humans; Male; Nausea; Neuroprotective Agents; Neuropsychological Tests; Peptide Fragments; Placebos; Plaque, Amyloid; Taurine; Treatment Outcome | 2006 |
Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer's disease: the ALZHEMED (Tramiprosate) experience.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Double-Blind Method; Female; GABA Agonists; Humans; Magnetic Resonance Imaging; Male; Research Design; Sensitivity and Specificity; Taurine | 2009 |
Effect of tramiprosate in patients with mild-to-moderate Alzheimer's disease: exploratory analyses of the MRI sub-group of the Alphase study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents; Severity of Illness Index; Taurine | 2009 |
Domain-specific cognitive effects of tramiprosate in patients with mild to moderate Alzheimer's disease: ADAS-cog subscale results from the Alphase Study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; GABA Agonists; Humans; Male; Memory; Neuroprotective Agents; Severity of Illness Index; Taurine; Treatment Outcome | 2009 |
Homotaurine in Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Cognition Disorders; Disorders of Excessive Somnolence; Female; Humans; Male; Parkinson Disease; Patient Dropouts; Severity of Illness Index; Single-Blind Method; Taurine; Treatment Outcome | 2015 |
Oral Administration of Forskolin, Homotaurine, Carnosine, and Folic Acid in Patients with Primary Open Angle Glaucoma: Changes in Intraocular Pressure, Pattern Electroretinogram Amplitude, and Foveal Sensitivity.
Topics: Administration, Oral; Aged; Anticonvulsants; Carnosine; Case-Control Studies; Colforsin; Dietary Supplements; Electroretinography; Female; Folic Acid; Fovea Centralis; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Taurine; Vasodilator Agents; Vitamin B Complex | 2016 |
Clinical Pharmacokinetics and Safety of ALZ-801, a Novel Prodrug of Tramiprosate in Development for the Treatment of Alzheimer's Disease.
Topics: Administration, Oral; Adult; Aged; Alzheimer Disease; Area Under Curve; Capsules; Dose-Response Relationship, Drug; Double-Blind Method; Female; Half-Life; Humans; Male; Middle Aged; Prodrugs; Tablets; Taurine; Valine; Young Adult | 2018 |
Clinical Effects of Tramiprosate in APOE4/4 Homozygous Patients with Mild Alzheimer's Disease Suggest Disease Modification Potential.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; Homozygote; Humans; Male; Mental Status and Dementia Tests; Nootropic Agents; Protein Aggregation, Pathological; Severity of Illness Index; Taurine; Treatment Outcome | 2017 |
Discovery and Identification of an Endogenous Metabolite of Tramiprosate and Its Prodrug ALZ-801 that Inhibits Beta Amyloid Oligomer Formation in the Human Brain.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Chromatography, Liquid; Cognition Disorders; Computer Simulation; Drug Administration Routes; Female; Humans; Male; Mental Status Schedule; Middle Aged; Models, Chemical; Nonlinear Dynamics; Peptide Fragments; Prodrugs; Propionates; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Taurine; Valine | 2018 |
136 other study(ies) available for taurine and tramiprosate
| Article | Year |
|---|---|
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
The depolarizing responses to GABA in rat sensory ganglia in vivo and in vitro. A study of the role of glial uptake.
Topics: Animals; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Muscimol; Neuroglia; Rats; Receptors, Neurotransmitter; Taurine | 1979 |
Homotaurine and muscimol mimic taurine and GABA effects on muscle tone and temperature regulation.
Topics: Amino Acids; Animals; Body Temperature Regulation; Electroencephalography; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intraventricular; Male; Muscimol; Muscle Tonus; Oxazoles; Rabbits; Taurine | 1978 |
[Effect of 3-aminopropanesulfonic acid of the electric activity of the cerebral cortex].
Topics: Animals; Cerebral Cortex; Evoked Potentials; Female; Male; Rats; Taurine | 1975 |
[Role of 5-hydroxytryptamine and of the acetylocholine in the anticonvulsive action of homotaurine].
Topics: Acetylcholine; Animals; Anticonvulsants; Cerebral Cortex; Male; Rats; Seizures; Serotonin; Taurine | 1975 |
Proposed antagonists at GABAB receptors that inhibit adenylyl cyclase in cerebellar granule cell cultures of rat.
Topics: Adenylyl Cyclase Inhibitors; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Taurine | 1992 |
Effects of taurine, homotaurine and GABA on hypothalamic and striatal dopamine metabolism.
Topics: Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Hypothalamus; Injections, Intraventricular; Male; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Taurine | 1992 |
GABAergic and cholinergic mediation in the antinociceptive action of homotaurine.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Baclofen; gamma-Aminobutyric Acid; Immersion; Male; Mice; Pain; Pain Measurement; Parasympathetic Nervous System; Reaction Time; Scopolamine; Taurine | 1992 |
Effects of alcohol dependence on shock-induced fighting: action of muscimol and homotaurine.
Topics: Aggression; Alcoholism; Animals; Body Weight; Electroshock; Ethanol; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Taurine | 1992 |
Role of dopamine and GABA in the control of motor activity elicited from the rat nucleus accumbens.
Topics: Animals; Baclofen; Dopamine; Dopamine Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Motor Activity; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, GABA-A; Sesterterpenes; Taurine | 1991 |
Effect of homotaurine in experimental analgesia tests.
Topics: Analgesics; Animals; Male; Mice; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine | 1991 |
Action of taurine, 3-aminopropanesulfonic acid, and GABA on the hindgut and heart of the cockroach, Leucophaea maderae.
Topics: Amino Acids; Animals; Bicuculline; Cockroaches; Digestive System; Digestive System Physiological Phenomena; gamma-Aminobutyric Acid; Heart; In Vitro Techniques; Neurotransmitter Agents; Organ Specificity; Picrotoxin; Taurine | 1991 |
GABAB receptor modulation of the release of substance P from capsaicin-sensitive neurones in the rat trachea in vitro.
Topics: Animals; Baclofen; Bicuculline; Capsaicin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substance P; Taurine; Trachea | 1991 |
Comparison of contractile responses of the guinea pig ileum longitudinal muscle to ethanol and GABAA agonists.
Topics: Animals; Atropine; Bicuculline; Chlorides; Ethanol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Taurine; Tetrodotoxin | 1990 |
GABAB receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Decerebrate State; Electric Stimulation; gamma-Aminobutyric Acid; Male; Muscimol; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine; Tubocurarine; Vascular Resistance | 1990 |
GABAA receptor-mediated stimulation of non-adrenergic non-cholinergic neurones in the dog ileocolonic junction.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Colon; Dogs; Electric Stimulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Nitroglycerin; Receptors, GABA-A; Taurine; Tetrodotoxin | 1990 |
Involvement of substance P in the excitatory action of GABAA agonists on cholinergic neurons in the guinea-pig ileum.
Topics: Animals; Capsaicin; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Peptide Fragments; Substance P; Taurine | 1987 |
GABAA receptor-mediated positive inotropism in guinea-pig isolated left atria: evidence for the involvement of capsaicin-sensitive nerves.
Topics: Animals; Baclofen; Bicuculline; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Muscimol; Myocardial Contraction; Neurons; Neuropeptides; Receptors, GABA-A; Taurine | 1989 |
Influence of GABA and ethylenediamine in the guinea-pig duodenum.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Duodenum; Electric Stimulation; Ethylenediamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Thiosemicarbazones | 1989 |
GABAergic drugs and lordosis behavior in the female rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Estradiol; Female; gamma-Aminobutyric Acid; Isoxazoles; Oxazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal; Taurine | 1989 |
An in vitro study of the relationship between GABA receptor function and propulsive motility in the distal colon of the rabbit.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Autonomic Nervous System; Baclofen; Colon; gamma-Aminobutyric Acid; Gastrointestinal Motility; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Picrotoxin; Rabbits; Receptors, GABA-A; Sesterterpenes; Taurine | 1989 |
Interaction of the pyrethroid insecticides tetramethrin and cypermethrin with enteric cholinergic transmission in the guinea-pig.
Topics: Animals; Cholinergic Fibers; Electric Stimulation; Female; Guinea Pigs; Ileum; Insecticides; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Pyrethrins; Receptors, GABA-A; Synaptic Transmission; Taurine; Veratridine | 1989 |
Comparison of the effects of intraventricular taurine, GABA and homotaurine on serum prolactin levels in male rats.
Topics: Animals; Anticonvulsants; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Prolactin; Rats; Rats, Inbred Strains; Taurine | 1989 |
GABA-related actions in isolated in vitro preparations of the rat small intestine.
Topics: Animals; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, GABA-A; Taurine | 1987 |
Cortisol: a potent biphasic modulator at GABAA-receptor complexes in the guinea pig isolated ileum.
Topics: Animals; Baclofen; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Ileum; In Vitro Techniques; Male; Muscle Contraction; Receptors, GABA-A; Taurine | 1987 |
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Indomethacin; Male; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stomach Ulcer; Taurine | 1988 |
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazenil; Flupenthixol; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nipecotic Acids; Receptors, GABA-A; Strychnine; Taurine; Tiagabine | 1988 |
The effect of peripherally administered GABA on noradrenaline-induced reflex vagal bradycardia in urethane anaesthetized rats.
Topics: Anesthesia; Animals; Drug Interactions; Electric Stimulation; gamma-Aminobutyric Acid; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Male; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Reflex; Taurine; Urethane; Vagotomy; Vagus Nerve | 1985 |
Involvement of noradrenaline in potentiation of the head-twitch response by GABA-related drugs.
Topics: Adrenergic beta-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Catecholamines; Diazepam; Dopamine; Drug Synergism; gamma-Aminobutyric Acid; Male; Methoxydimethyltryptamines; Metoprolol; Mice; Muscimol; Norepinephrine; Pentobarbital; Picrotoxin; Stereotyped Behavior; Taurine | 1986 |
Modulation of [3H]diazepam binding in rat cortical membranes by GABAA agonists.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Cell Membrane; Cerebral Cortex; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isonicotinic Acids; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, GABA-A; Taurine | 1985 |
GABAA and GABAB receptors in detrusor strips from guinea-pig bladder dome.
Topics: Animals; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1985 |
Inhibitory effect of GABA on sympathetic neurotransmission in rabbit ear artery.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Arteries; Baclofen; Ear, External; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Norepinephrine; Picrotoxin; Potassium; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Taurine; Vasoconstriction | 1985 |
Dual effect of GABA on the contractile activity of the guinea-pig isolated urinary bladder.
Topics: Acetylcholine; Animals; Baclofen; Dimethylphenylpiperazinium Iodide; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1985 |
The locomotor-reducing effects of GABAergic drugs do not depend on the GABAA receptor.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Isoxazoles; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine | 1985 |
Evidence that antagonism by delta-aminovaleric acid of GABAB receptors in the guinea-pig ileum may be due to an interaction between GABAA and GABAB receptors.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Bicuculline; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Isonicotinic Acids; Male; Muscle, Smooth; Receptors, GABA-A; Taurine | 1986 |
Evidence for prejunctional GABAB receptors mediating inhibition of ovarian follicle contraction induced by nerve stimulation.
Topics: Animals; Atropine; Baclofen; Bicuculline; Cattle; Electric Stimulation; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Ovarian Follicle; Phentolamine; Receptors, GABA-A; Synaptic Membranes; Taurine; Tetrodotoxin | 1986 |
GABA A receptor mediated neurogenic inhibition of motility in the small intestine of urethane-anaesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; Gastrointestinal Motility; Hexamethonium Compounds; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Propranolol; Rats; Receptors, GABA-A; Taurine; Tetrodotoxin; Urethane | 1986 |
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature | 1986 |
Baclofen activates two distinct receptors in the rat spinal cord and guinea pig ileum.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Ileum; Male; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Stereoisomerism; Taurine | 1986 |
GABA-A and GABA-B receptors in the cuneate nucleus of the rat in vivo.
Topics: Animals; Baclofen; Electric Stimulation; Evoked Potentials; Male; Medulla Oblongata; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine | 1986 |
Characterization of gamma-aminobutyric acid receptors in the neurointermediate lobe of the amphibian Xenopus laevis.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Kinetics; Melanocyte-Stimulating Hormones; Picrotoxin; Pituitary Gland; Receptors, GABA-A; Taurine; Xenopus | 1987 |
GABA-receptor stimulation enhances norepinephrine-induced polyphosphoinositide metabolism in rat hippocampal slices.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Inositol Phosphates; Male; Muscimol; Norepinephrine; Phosphatidic Acids; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine | 1987 |
Liquid chromatographic determination of taurine in whole blood, plasma and platelets.
Topics: 3-Mercaptopropionic Acid; Blood Platelets; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Indicators and Reagents; o-Phthalaldehyde; Taurine | 1988 |
[Effects of GABA and homotaurine on the colonic motility of the guinea pig].
Topics: Animals; Colon; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Taurine | 1987 |
Effect of taurine and homotaurine on bile acid metabolism in dietary hyperlipidemic rats.
Topics: Animals; Bile; Bile Acids and Salts; Biliary Tract; Cholesterol, Dietary; Chromatography, High Pressure Liquid; Feces; Hypercholesterolemia; Male; Rats; Rats, Inbred Strains; Taurine | 1986 |
Spinal and supraspinal components of GABAergic inhibition of the micturition reflex in rats.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Kinetics; Male; Picrotoxin; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Taurine; Urination | 1987 |
Uptake inhibitors potentiate gamma-aminobutyric acid-induced contractile responses in the isolated ileum of the guinea-pig.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Sesterterpenes; Taurine | 1987 |
Opposite effects of 2-aminoethanesulfonic acid (taurine) and aminomethanesulfonic acid on calcium ion uptake in rat retinal preparations.
Topics: Adenosine Triphosphate; Animals; Calcium; In Vitro Techniques; Membranes; Rats; Rats, Inbred Strains; Retina; Sulfonic Acids; Taurine | 1985 |
Taurine and its derivatives alter brain dopamine metabolism similarly to GABA in mice and rats.
Topics: Animals; Apomorphine; Benzothiadiazines; Brain; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Intraventricular; Limbic System; Mice; Rats; Taurine | 1985 |
GABAergic agents as anticonvulsants in baboons with photosensitive epilepsy.
Topics: Aminocaproates; Animals; Anticonvulsants; Baclofen; Carbolines; Cerebral Cortex; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Papio; Photic Stimulation; Receptors, Cell Surface; Receptors, GABA-A; Taurine; Vigabatrin | 1984 |
Similar properties of [35S]t-butylbicyclophosphorothionate receptor and coupled components of the GABA receptor-ionophore complex in brains of human, cow, rat, chicken and fish.
Topics: Androstanes; Animals; Azasteroids; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cattle; Chickens; Convulsants; Female; Fishes; Humans; Ivermectin; Lactones; Male; Middle Aged; Muscimol; Rats; Receptors, GABA-A; Taurine | 1984 |
A homotaurine derivative reduces the voluntary intake of ethanol by rats: are cerebral GABA receptors involved?
Topics: Acamprosate; Alcohol Drinking; Animals; Anticonvulsants; Brain; Calcium Chloride; Male; Rats; Receptors, GABA-A; Taurine | 1984 |
Effect of gamma-aminobutyric acid agonists, glycine, taurine and neuropeptides on acetylcholine release from the rabbit retina.
Topics: Acetylcholine; Animals; Baclofen; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neurotransmitter Agents; Photic Stimulation; Rabbits; Retina; Strychnine; Taurine | 1983 |
omega-Aminosulfonic acids as depressant or excitant compounds: their effect on the behavior and electroencephalogram of young chickens.
Topics: Alkanesulfonates; Alkanesulfonic Acids; Animals; Behavior, Animal; Central Nervous System Depressants; Central Nervous System Stimulants; Chickens; Electroencephalography; gamma-Aminobutyric Acid; Pentylenetetrazole; Picrotoxin; Structure-Activity Relationship; Strychnine; Taurine; Tubocurarine | 1983 |
GABAB receptor mediated inhibition of field stimulation-induced contractions of rabbit bladder muscle in-vitro.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Atropine; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Picrotoxin; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1984 |
Inhibition of GABA uptake potentiates the conductance increase produced by GABA-mimetic compounds on single neurones in isolated olfactory cortex slices of the guinea-pig.
Topics: Animals; Central Nervous System; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isonicotinic Acids; Muscimol; Neural Conduction; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Olfactory Pathways; Proline; Sodium; Taurine | 1984 |
GABA induced changes in acetylcholine release from slices of guinea-pig brain.
Topics: Acetylcholine; Animals; Brain; Ethanolamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Potassium Chloride; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1982 |
Effect of 3-aminopropanesulfonic acid and allylglycine on prolactin release in male rats.
Topics: Allylglycine; Animals; gamma-Aminobutyric Acid; Glycine; Kinetics; Male; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sulpiride; Taurine | 1981 |
GABAA and GABAB receptor-mediated effects in guinea-pig ileum.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1983 |
Biphasic effects of baclofen on phrenic motoneurons: possible involvement of two types of gamma-aminobutyric acid (GABA) receptors.
Topics: Animals; Baclofen; Bicuculline; Carbon Dioxide; Cats; Dose-Response Relationship, Drug; Female; Male; Motor Neurons; Phrenic Nerve; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1983 |
Effects of glial uptake and desensitization on the activity of gamma-aminobutyric acid (GABA) and its analogs at the cat dorsal root ganglion.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Ganglia, Spinal; Iontophoresis; Male; Membrane Potentials; Muscimol; Neuroglia; Neuromuscular Depolarizing Agents; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1983 |
GABAB receptor mediated inhibition of field stimulation induced contractions of detrusor muscle strips from newborn rats.
Topics: Aging; Animals; Animals, Newborn; Atropine; Baclofen; Electric Stimulation; Female; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1984 |
Comparison of guanidinoethanesulfonic acid, homotaurine and beta-alanine in a learning situation.
Topics: Alanine; Animals; beta-Alanine; Brain Chemistry; gamma-Aminobutyric Acid; Learning; Male; Rats; Rats, Inbred Strains; Taurine | 1983 |
Penicillin spikes in rats. Limitations of a simple model for the study of anticonvulsants.
Topics: Action Potentials; Animals; Anticonvulsants; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Isoxazoles; Male; Penicillins; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Taurine; Time Factors | 1984 |
Mechanisms of the inhibitory cardiovascular effects of taurine and homotaurine.
Topics: Animals; Atenolol; Atropine; Blood Pressure; Bradycardia; Depression, Chemical; Heart Rate; Hypotension; Male; Premedication; Rats; Rats, Inbred Strains; Reserpine; Sympathetic Nervous System; Taurine | 1983 |
Homotaurine: a GABAB antagonist in guinea-pig ileum.
Topics: Animals; Baclofen; Electric Stimulation; GABA Antagonists; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Picrotoxin; Taurine | 1983 |
Effects of baclofen on synaptically-induced cell firing in the rat hippocampal slice.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Pyramidal Tracts; Rats; Rats, Inbred Strains; Stereoisomerism; Taurine | 1983 |
Ketamine potentiates the responses of the rat superior cervical ganglion to GABA.
Topics: Animals; Drug Synergism; gamma-Aminobutyric Acid; Ganglia, Spinal; Ketamine; Male; Nicotinic Acids; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Taurine | 1984 |
Activating effects of homotaurine and taurine on corticoreticular epilepsy.
Topics: Animals; beta-Alanine; Cats; Electrodes, Implanted; Electroencephalography; gamma-Aminobutyric Acid; Male; Seizures; Taurine | 1981 |
Carnosine-synthetase inhibition of beta-alanine analogues.
Topics: Alanine; Amino Acids; Amino Acids, Neutral; Animals; beta-Alanine; Brain; Chickens; Female; In Vitro Techniques; Male; Muscles; Myocardium; Peptide Synthases; Rats; Rats, Inbred Strains; Taurine | 1982 |
Uptake, autoradiography and release of taurine and homotaurine from retinal tissue.
Topics: Animals; Autoradiography; Cattle; Kinetics; Osmolar Concentration; Potassium; Retina; Taurine; Tritium | 1983 |
The effect of taurine on high potassium-and noradrenaline-induced contraction in rabbit ear artery.
Topics: Alanine; Animals; Arteries; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rabbits; Taurine; Verapamil | 1982 |
Two actions of gamma-aminobutyric acid on the responses of the isolated basilar artery from the rabbit.
Topics: Animals; Baclofen; Basilar Artery; Drug Interactions; Electric Stimulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Serotonin; Taurine | 1982 |
gamma-Aminobutyric acid action in guinea-pig ileal myenteric plexus.
Topics: Amino Acids; Animals; Atropine; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle, Smooth; Myenteric Plexus; Taurine; Tetrodotoxin | 1982 |
Excitability of primary afferents in feline spinal cord: taurine, homotaurine, and gamma-aminobutyric acid compared.
Topics: Afferent Pathways; Animals; Anticonvulsants; Cats; gamma-Aminobutyric Acid; Semicarbazides; Spinal Cord; Taurine | 1982 |
Cardiovascular and ventilatory effects of taurine and homotaurine in anaesthetized rats.
Topics: Animals; Blood Pressure; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Respiration; Taurine; Tidal Volume | 1982 |
Homotaurine (3 aminopropanesulfonic acid; 3APS) protects from the convulsant and cytotoxic effect of systemically administered kainic acid.
Topics: Animals; Anticonvulsants; Brain; Caudate Nucleus; Electroencephalography; Evoked Potentials; Kainic Acid; Male; Muscimol; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Taurine | 1982 |
Inhibitory actions of taurocyamine, hypotaurine, homotaurine, taurine and GABA on spike discharges of Purkinje cells, and localization of sensitive sites, in guinea pig cerebellar slices.
Topics: Animals; Cerebellum; Culture Techniques; Evoked Potentials; gamma-Aminobutyric Acid; Guanidines; Guinea Pigs; Interneurons; Neural Inhibition; Picrotoxin; Purkinje Cells; Strychnine; Taurine | 1981 |
Competitive inhibition by 3-aminopropanesulfonic acid and gamma-aminobutyric acid of carnitine transport in rat brain slices.
Topics: Animals; Binding, Competitive; Biological Transport; Brain; Carnitine; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Rats; Taurine | 1981 |
Central cardiovascular effects of taurine: comparison with homotaurine and muscimol.
Topics: Animals; Bicuculline; Cats; Central Nervous System; Hemodynamics; Injections, Intraventricular; Muscimol; Oxazoles; Strychnine; Taurine | 1981 |
Interaction of the neurotoxic pesticides ivermectin and lindane with the enteric GABAA receptor-ionophore complex in the guinea-pig.
Topics: Animals; Chloride Channels; Female; GABA-A Receptor Antagonists; Guinea Pigs; Hexachlorocyclohexane; In Vitro Techniques; Intestine, Small; Isometric Contraction; Ivermectin; Male; Membrane Proteins; Muscle, Smooth; Picrotoxin; Pyridazines; Receptors, GABA-A; Scopolamine; Sesterterpenes; Taurine; Tetrodotoxin | 1993 |
Mechanism of action of gamma-aminobutyric acid on frog melanotrophs.
Topics: Adenylyl Cyclases; Animals; Baclofen; Calcium; Calcium Channels; Colforsin; Cyclic AMP; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inositol Phosphates; Male; Melanocyte-Stimulating Hormones; Models, Biological; Pituitary Gland, Posterior; Rana ridibunda; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; Taurine | 1995 |
Cyclic amidine analogues of taurine and homotaurine: synthesis and effects on rat skeletal muscle.
Topics: Amidines; Animals; In Vitro Techniques; Male; Muscle, Skeletal; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfonic Acids; Taurine | 1994 |
Effects of taurine analogues on chloride channel conductance of rat skeletal muscle fibers: a structure-activity relationship investigation.
Topics: Animals; Chloride Channels; Electrophysiology; In Vitro Techniques; Male; Membrane Potentials; Muscles; Rats; Rats, Wistar; Structure-Activity Relationship; Taurine | 1994 |
Effects of intraventricular taurine, homotaurine and GABA on serum prolactin and thyrotropin levels in female and in male rats.
Topics: Animals; Dopamine; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Prolactin; Radioimmunoassay; Rats; Rats, Wistar; Sex Characteristics; Taurine; Thyrotropin | 1993 |
gamma-Aminobutyric acid stimulates electrolyte transport in the guinea pig ileum in vitro.
Topics: Analysis of Variance; Animals; Atropine; Autoradiography; Baclofen; Bicuculline; Biological Transport; Capsaicin; Electrolytes; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Neurons, Afferent; Parasympatholytics; Pyrilamine; Taurine | 1996 |
Structural determinants of activity at the GABAB receptor. A comparison of phosphoethanolamine and related GABA analogs.
Topics: Crystallography, X-Ray; Electrochemistry; Esters; Ethanolamines; gamma-Aminobutyric Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Oxygen; Propylamines; Receptors, GABA-B; Structure-Activity Relationship; Taurine | 1995 |
Interaction among alfaxalone, pregnenolone sulfate, and two GABAA agonists on hippocampal slices.
Topics: Allosteric Regulation; Animals; Evoked Potentials; GABA Agonists; GABA-A Receptor Agonists; Hippocampus; Male; Mice; Muscimol; Pregnanediones; Pregnenolone; Taurine | 1996 |
GABA(B) receptors and opioid mechanisms involved in homotaurine-induced analgesia.
Topics: Analgesics, Opioid; Animals; Drug Interactions; GABA Agonists; Male; Mice; Morphine; Pain Threshold; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Opioid; Taurine | 1998 |
Effects of muscimol or homotaurine on sleep-wake states in alcohol-dependent rats during withdrawal.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Behavior, Animal; Body Weight; Central Nervous System Depressants; Ethanol; GABA Agonists; Male; Muscimol; Polysomnography; Rats; Rats, Wistar; Sleep; Substance Withdrawal Syndrome; Taurine; Wakefulness | 1998 |
Rat gastroduodenal motility in vivo: interaction of GABA and VIP in control of spontaneous relaxations.
Topics: Animals; Bicuculline; Duodenum; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myoelectric Complex, Migrating; NG-Nitroarginine Methyl Ester; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stomach; Taurine; Vasoactive Intestinal Peptide | 1998 |
Locally infused taurine, GABA and homotaurine alter differently the striatal extracellular concentrations of dopamine and its metabolites in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Male; Motor Activity; Perfusion; Phenylacetates; Rats; Rats, Wistar; Taurine; Tetrodotoxin | 1998 |
Determination of homotaurine as impurity in calcium acamprosate by capillary zone electrophoresis.
Topics: Acamprosate; Calibration; Electrolytes; Electrophoresis, Capillary; Fluorescamine; Injections; Linear Models; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet; Taurine | 1999 |
Methylene blue photosensitized oxidation of cysteine sulfinic acid and other sulfinates: the involvement of singlet oxygen and the azide paradox.
Topics: Aerobiosis; Anaerobiosis; Cysteine; Deuterium Oxide; Kinetics; Methylene Blue; Models, Chemical; Neurotransmitter Agents; Oxidation-Reduction; Oxygen; Photochemistry; Singlet Oxygen; Sodium Azide; Sulfinic Acids; Taurine | 2000 |
Effect of experimental diabetes on GABA-mediated inhibition of neurally induced contractions in rat isolated trachea.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Wistar; Taurine; Tetrodotoxin; Trachea; Vasodilator Agents | 2000 |
Effects of DAGO on the rodent hippocampal evoked potentials using different perfusion solutions.
Topics: Analgesics; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Agonists; Hippocampus; In Vitro Techniques; Isotonic Solutions; Magnesium Sulfate; Male; Mice; Mice, Inbred Strains; Perfusion; Rats; Rats, Wistar; Taurine | 2000 |
Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia.
Topics: beta-Alanine; Butyrates; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Deltaproteobacteria; Electrophoresis, Polyacrylamide Gel; Kinetics; Models, Chemical; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Oxaloacetic Acid; Pyridoxal Phosphate; Taurine; Time Factors; Transaminases; Ultraviolet Rays | 2000 |
Role of K+ -channels in homotaurine-induced analgesia.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Analgesics; Animals; GABA Agonists; Mice; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Taurine; Tetraethylammonium | 2001 |
Synthesis and characterization of N,N-dichlorinated amino acids: taurine, homotaurine, GABA and L-leucine.
Topics: gamma-Aminobutyric Acid; Leucine; Taurine | 2001 |
Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release.
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Animals; Central Nervous System Depressants; Dopamine; Dose-Response Relationship, Drug; Ethanol; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Taurine | 2002 |
The regulation of alpha-MSH release by GABA is mediated by a chloride-dependent [Ca2+]c increase in frog melanotrope cells.
Topics: alpha-MSH; Animals; Calcium; Cell Division; Cells, Cultured; Chlorides; Cytosol; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Melanotrophs; Rana esculenta; Taurine | 2005 |
Diazepam inhibits the induction and maintenance of LTP of C-fiber evoked field potentials in spinal dorsal horn of rats.
Topics: Animals; Diazepam; Electrophysiology; Evoked Potentials; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Long-Term Potentiation; Male; Nerve Fibers, Unmyelinated; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Taurine | 2006 |
Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Brain; Cell Death; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; GABA Agonists; Humans; Mice; Mice, Transgenic; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Taurine | 2007 |
Therapies for Alzheimer's disease.
Topics: Alzheimer Disease; Alzheimer Vaccines; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Cholinesterase Inhibitors; Clinical Trials as Topic; Excitatory Amino Acid Antagonists; GABA Agonists; Humans; Immunization; Memantine; Receptors, N-Methyl-D-Aspartate; Taurine | 2007 |
Taurine, an inducer for tau polymerization and a weak inhibitor for amyloid-beta-peptide aggregation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Molecular Structure; Neurofibrillary Tangles; Plaque, Amyloid; Protein Binding; tau Proteins; Taurine | 2007 |
Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate.
Topics: Burkholderia; Culture Media; Glutamate Dehydrogenase (NADP+); Glutamic Acid; Ketoglutaric Acids; Models, Biological; Molecular Sequence Data; Nitrogen; Propionates; Taurine; Transaminases | 2008 |
Homotaurine metabolized to 3-sulfopropanoate in Cupriavidus necator H16: enzymes and genes in a patchwork pathway.
Topics: Bacterial Proteins; Cupriavidus necator; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Bacterial; Models, Biological; Propionates; Reverse Transcriptase Polymerase Chain Reaction; Succinate-Semialdehyde Dehydrogenase; Taurine; Transaminases | 2009 |
Homotaurine: a failed drug for Alzheimer's disease and now a nutraceutical for memory protection.
Topics: Clinical Trials as Topic; Dietary Supplements; Humans; Memory Disorders; Nootropic Agents; Taurine | 2009 |
Investigation of the noncovalent interactions between anti-amyloid agents and amyloid beta peptides by ESI-MS.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Humans; Molecular Sequence Data; Molecular Weight; Peptide Library; Protein Binding; Sequence Analysis, Protein; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Taurine | 2010 |
Reversed-phase liquid chromatographic determination of tramiprosate in rat plasma using evaporative light scattering detector.
Topics: Animals; Chromatography, Reverse-Phase; Drug Stability; Least-Squares Analysis; Light; Linear Models; Male; Nebulizers and Vaporizers; Rats; Rats, Wistar; Reproducibility of Results; Scattering, Radiation; Taurine; Temperature | 2011 |
Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates.
Topics: Amyloid; Benzenesulfonates; Diabetes Mellitus, Type 2; Heparitin Sulfate; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Lissamine Green Dyes; Plaque, Amyloid; Protein Processing, Post-Translational; Taurine | 2011 |
Gas-phase binding energies for non-covalent Aβ-40 peptide/small molecule complexes from CID mass spectrometry and RRKM theory.
Topics: Alkanesulfonic Acids; Amyloid beta-Peptides; Cyclohexylamines; Gases; Kinetics; Mass Spectrometry; Models, Chemical; Models, Molecular; Molecular Conformation; Peptide Fragments; Protein Binding; Sulfonic Acids; Taurine; Thermodynamics | 2011 |
Precolumn derivatization followed by liquid chromatographic separation and determination of tramiprosate in rat plasma by fluorescence detector: application to pharmacokinetics.
Topics: Animals; Anticonvulsants; Calibration; Chromatography, High Pressure Liquid; Limit of Detection; Rats; Rats, Wistar; Reproducibility of Results; Spectrometry, Fluorescence; Taurine | 2011 |
Tramiprosate protects neurons against ischemic stroke by disrupting the interaction between PSD95 and nNOS.
Topics: Animals; Apoptosis; Brain Ischemia; Disks Large Homolog 4 Protein; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; PC12 Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stroke; Taurine | 2014 |
Modulation of GABA-A receptors of astrocytes and STC-1 cells by taurine structural analogs.
Topics: Animals; Astrocytes; Binding Sites; Caenorhabditis elegans; Cell Line; Computer Simulation; Electrophysiology; Humans; Kinetics; Ligands; Mice; Patch-Clamp Techniques; Perfusion; Picrotoxin; Protein Binding; Protein Conformation; Receptors, GABA-A; Taurine | 2014 |
Intravitreal injection of forskolin, homotaurine, and L-carnosine affords neuroprotection to retinal ganglion cells following retinal ischemic injury.
Topics: Animals; Carnosine; Cell Survival; Colforsin; Disease Models, Animal; Drug Synergism; Glaucoma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Intraocular Pressure; Intravitreal Injections; Ischemia; Male; Neuroprotective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Retinal Ganglion Cells; Retinal Vessels; Signal Transduction; Taurine | 2015 |
QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Carrier Proteins; Catechin; Disease Models, Animal; Ferredoxin-NADP Reductase; Humans; Inositol; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Oligopeptides; Protein Aggregation, Pathological; Taurine | 2015 |
Homotaurine Effects on Hippocampal Volume Loss and Episodic Memory in Amnestic Mild Cognitive Impairment.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Chi-Square Distribution; Cognitive Dysfunction; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Longitudinal Studies; Magnetic Resonance Imaging; Male; Memory, Episodic; Mental Status Schedule; Middle Aged; Neuroprotective Agents; Neuropsychological Tests; Taurine | 2016 |
An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antineoplastic Agents; Bexarotene; Caenorhabditis elegans; Drug Discovery; Humans; In Vitro Techniques; Kinetics; Models, Animal; Molecular Sequence Data; Peptide Fragments; Protein Multimerization; Recombinant Proteins; Taurine; Tetrahydronaphthalenes | 2016 |
Accuracy of cerebrospinal fluid Aβ1-42 measurements: evaluation of pre-analytical factors using a novel Elecsys immunosassay.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antibodies; Cryoprotective Agents; Freezing; Humans; Immunoassay; Peptide Fragments; Polysorbates; Protein Stability; Taurine | 2017 |
Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer's Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Dose-Response Relationship, Drug; Drug Design; Genetic Predisposition to Disease; Humans; Ion Mobility Spectrometry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Dynamics Simulation; Peptide Fragments; Prodrugs; Taurine | 2017 |
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX).
Topics: Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Cell Line, Tumor; Drug Synergism; Humans; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Peripheral Nervous System Diseases; Taurine; TRPA1 Cation Channel | 2017 |
Cytoprotective Effects of Citicoline and Homotaurine against Glutamate and High Glucose Neurotoxicity in Primary Cultured Retinal Cells.
Topics: Cells, Cultured; Cytidine Diphosphate Choline; Glucose; Glutamic Acid; Neurotoxicity Syndromes; Retina; Taurine | 2017 |
Synergistic Inhibitory Effect of GQDs-Tramiprosate Covalent Binding on Amyloid Aggregation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidogenic Proteins; Amyloidosis; Diabetes Mellitus, Type 2; Graphite; Humans; Peptide Fragments; Quantum Dots; Taurine | 2018 |
Homotaurine, a safe blood-brain barrier permeable GABA
Topics: Administration, Oral; Animals; Blood-Brain Barrier; Disease Models, Animal; GABA Agonists; Mice; Mice, Inbred C57BL; Multiple Sclerosis; T-Lymphocytes, Regulatory; Taurine; Th1 Cells; Th17 Cells | 2018 |
Homotaurine Treatment Enhances CD4
Topics: Animals; Blood Glucose; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Synergism; Female; GABA Agonists; Humans; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Mice, Inbred NOD; Mice, SCID; Muromonab-CD3; Taurine | 2019 |
Protective Efficacy of a Dietary Supplement Based on Forskolin, Homotaurine, Spearmint Extract, and Group B Vitamins in a Mouse Model of Optic Nerve Injury.
Topics: Animals; Colforsin; Dietary Supplements; Glaucoma; Mentha spicata; Mice; Optic Nerve Injuries; Plant Extracts; Taurine; Vitamin B Complex | 2019 |
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Catalytic Domain; Cell Line; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Humans; Male; Mice; Mice, Transgenic; Molecular Docking Simulation; Molecular Structure; Pyridinium Compounds; Structure-Activity Relationship; Taurine | 2020 |
A Dietary Combination of Forskolin with Homotaurine, Spearmint and B Vitamins Protects Injured Retinal Ganglion Cells in a Rodent Model of Hypertensive Glaucoma.
Topics: Animals; Colforsin; Dietary Supplements; Disease Models, Animal; Female; Glaucoma; Intraocular Pressure; Male; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Nutritional Physiological Phenomena; Ocular Hypertension; Retinal Ganglion Cells; Taurine; Vitamin B Complex | 2020 |
9R, the cholinesterase and amyloid beta aggregation dual inhibitor, as a multifunctional agent to improve cognitive deficit and neuropathology in the triple-transgenic Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain Chemistry; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Female; Humans; Injections, Intraperitoneal; Maze Learning; Mice; Mice, Transgenic; Motor Activity; Neuroprotective Agents; tau Proteins; Taurine | 2020 |
Effects of Citicoline, Homotaurine, and Vitamin E on Contrast Sensitivity and Visual-Related Quality of Life in Patients with Primary Open-Angle Glaucoma: A Preliminary Study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Antioxidants; Contrast Sensitivity; Cross-Over Studies; Cytidine Diphosphate Choline; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Neuroprotective Agents; Pilot Projects; Quality of Life; Random Allocation; Surveys and Questionnaires; Taurine; Vitamin E | 2020 |
Homotaurine limits the spreading of T cell autoreactivity within the CNS and ameliorates disease in a model of multiple sclerosis.
Topics: Animals; Antigen Presentation; Antigen-Presenting Cells; Cell Proliferation; Central Nervous System; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; gamma-Aminobutyric Acid; Mice, Inbred C57BL; Multiple Sclerosis; Myelin Proteolipid Protein; Peptide Fragments; Recurrence; Spleen; T-Lymphocytes; Taurine | 2021 |
Curcumin and Homotaurine Suppress Amyloid-β
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Brain; Curcumin; Humans; Peptide Fragments; Taurine | 2021 |
Levels of taurine, hypotaurine and homotaurine, and amino acids profiles in selected commercial seaweeds, microalgae, and algae-enriched food products.
Topics: Amino Acids; Animals; Chlorella vulgaris; Food, Fortified; Microalgae; Rhodophyta; Seaweed; Taurine | 2022 |
IL-33 and IL-10 Serum Levels Increase in MCI Patients Following Homotaurine Treatment.
Topics: Alzheimer Disease; Cognitive Dysfunction; Cytokines; Humans; Interleukin-10; Interleukin-18; Interleukin-33; Taurine | 2022 |
Taurine, homotaurine, GABA and hydrophobic amino acids content influences "in vitro" antioxidant and SIRT1 modulation activities of enzymatic protein hydrolysates from algae.
Topics: Amino Acids; Antifibrinolytic Agents; Antioxidants; gamma-Aminobutyric Acid; Humans; Protein Hydrolysates; Sirtuin 1; Taurine | 2022 |