tau 284 has been researched along with diphenhydramine in 3 studies
| Studies (tau 284) | Trials (tau 284) | Recent Studies (post-2010) (tau 284) | Studies (diphenhydramine) | Trials (diphenhydramine) | Recent Studies (post-2010) (diphenhydramine) |
|---|---|---|---|---|---|
| 52 | 18 | 21 | 4,146 | 415 | 542 |
| Protein | Taxonomy | tau 284 (IC50) | diphenhydramine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.98 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 3.542 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 1.05 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.372 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.162 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.346 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.647 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 3.542 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 1.295 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.98 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.171 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.118 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.8852 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, X; Funaki, Y; Ishikawa, Y; Itoh, M; Iwata, R; Kato, M; Miyake, M; Tashiro, M; Watanuki, S; Yanai, K | 1 |
| Funaki, Y; Kato, M; Okamura, N; Shibuya, K; Tashiro, M; Yanai, K; Yoshikawa, T; Zhang, D | 1 |
| Kanamitsu, K; Kusuhara, H; Nagaya, Y; Nozaki, Y; Sugiyama, Y | 1 |
2 trial(s) available for tau 284 and diphenhydramine
| Article | Year |
|---|---|
Brain histamine H1 receptor occupancy of orally administered antihistamines, bepotastine and diphenhydramine, measured by PET with 11C-doxepin.
Topics: Administration, Oral; Adult; Brain; Carbon Radioisotopes; Diphenhydramine; Doxepin; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Piperidines; Positron-Emission Tomography; Pyridines; Receptors, Histamine H1; Sleep Stages | 2008 |
Next-day residual sedative effect after nighttime administration of an over-the-counter antihistamine sleep aid, diphenhydramine, measured by positron emission tomography.
Topics: Administration, Oral; Brain; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Male; Nonprescription Drugs; Piperidines; Positron-Emission Tomography; Pyridines; Receptors, Histamine H1; Sleep Initiation and Maintenance Disorders; Young Adult | 2010 |
1 other study(ies) available for tau 284 and diphenhydramine
| Article | Year |
|---|---|
Quantitative prediction of histamine H1 receptor occupancy by the sedative and non-sedative antagonists in the human central nervous system based on systemic exposure and preclinical data.
Topics: Animals; Brain; Central Nervous System; Diphenhydramine; Histamine H1 Antagonists; Humans; Ketotifen; Macaca fascicularis; Male; Mice; Mice, Inbred Strains; Olopatadine Hydrochloride; Piperidines; Positron-Emission Tomography; Pyridines; Receptors, Histamine H1; Time Factors | 2017 |