tasiamide-b has been researched along with 4-amino-3-hydroxy-5-phenylpentanoic-acid* in 1 studies
1 other study(ies) available for tasiamide-b and 4-amino-3-hydroxy-5-phenylpentanoic-acid
Article | Year |
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Total synthesis and stereochemical reassignment of tasiamide B.
The first total synthesis of tasiamide B, an octapeptide bearing 4-amino-3-hydroxy-5-phenylpentanoic acid unit isolated from the marine cyanobacteria Symploca sp. is described. A simple and efficient way was found to avoid the pyroglutamylation of N(alpha)-Me-Gln and led to a reassignment of the N(alpha)-Me-L-Phe of tasiamide B to be N(alpha)-Me-D-Phe, which was also supported by 1D and 2D NMR. Topics: Amino Acids; Cyanobacteria; Magnetic Resonance Spectroscopy; Oligopeptides; Stereoisomerism | 2010 |