tartrolon-b has been researched along with laulimalide* in 1 studies
1 review(s) available for tartrolon-b and laulimalide
Article | Year |
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Lessons learned from macrolide synthesis.
The highlights of three macrolide syntheses recently completed in our laboratory are described. In the epothilone B synthesis we developed the "early epoxide approach," which resulted in the first completely stereocontrolled synthesis of this natural product. In the laulimalide synthesis our contribution was the auxiliary controlled ene-macrocyclization and Sharpless' kinetic resolution for achieving a regioselective epoxidation of two pseudo-enantiomorphic allylic alcohol subunits. The tartrolon B synthesis was the first to be completed. In this case, a substrate controlled aldol addition was used to assemble the entire carbon skeleton of the compound. Topics: Borates; Cyclization; Epothilones; Epoxy Compounds; Macrolides; Stereoisomerism; Taxoids | 2004 |