tariquidar has been researched along with tryptoquivaline in 10 studies
| Studies (tariquidar) | Trials (tariquidar) | Recent Studies (post-2010) (tariquidar) | Studies (tryptoquivaline) | Trials (tryptoquivaline) | Recent Studies (post-2010) (tryptoquivaline) |
|---|---|---|---|---|---|
| 210 | 16 | 138 | 83 | 0 | 28 |
| 210 | 16 | 138 | 29 | 0 | 15 |
| Protein | Taxonomy | tariquidar (IC50) | tryptoquivaline (IC50) |
|---|---|---|---|
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.808 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 0.7345 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klinkhammer, W; Pick, A; Wiese, M | 1 |
| Altmann, KH; Bartholomaeus, R; Bauer, S; Bause, M; Bernhardt, G; Buschauer, A; Jackson, SM; Koenig, B; Kowal, J; Locher, KP; Manolaridis, I; Stahlberg, H; Taylor, NMI; Zechner, M | 1 |
| Bernhardt, G; Buschauer, A; Egger, M; Fricker, G; König, B; Kühnle, M; Mahringer, A; Müller, C | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Bauer, S; Bernhardt, G; Buschauer, A; König, B; Kühnle, M; Ochoa-Puentes, C | 1 |
| Bernhardt, G; Buschauer, A; König, B; Obreque-Balboa, JE; Sun, Q | 1 |
| Hsiao, SH; Hsieh, CH; Huang, YH; Hung, TH; Li, YQ; Lu, YJ; Tuo, WC; Wu, CP; Yang, CC | 1 |
| Bernhardt, G; Buschauer, A; König, B; Ochoa-Puentes, C; Peña-Solórzano, D; Scholler, M | 1 |
| Chan, KF; Chan, TH; Chong, TC; Chow, LMC; Cui, J; Hu, X; Law, MC; Wong, ILK; Zhu, X | 1 |
| Antoni, F; Bauer, S; Bause, M; Bernhardt, G; Buschauer, A; Jackson, SM; König, B; Locher, KP; Manolaridis, I; Scholler, M; Stark, SA | 1 |
1 review(s) available for tariquidar and tryptoquivaline
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
9 other study(ies) available for tariquidar and tryptoquivaline
| Article | Year |
|---|---|
Specific inhibitors of the breast cancer resistance protein (BCRP).
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzamides; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Chlorophyll; Diketopiperazines; Drug Resistance, Multiple; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Imatinib Mesylate; Indoles; Neoplasm Proteins; Novobiocin; Piperazines; Pyrimidines; Quinolines; Structure-Activity Relationship | 2010 |
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily G, Member 2; Binding Sites; Cholesterol; Cryoelectron Microscopy; Diketopiperazines; Drug Design; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 4 or More Rings; Humans; Hydrolysis; Indoles; Kinetics; Lipids; Molecular Structure; Neoplasm Proteins; Phospholipids; Protein Binding; Protein Multimerization; Quinolines; Structure-Activity Relationship; Substrate Specificity | 2018 |
Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Female; Humans; Inhibitory Concentration 50; Multidrug Resistance-Associated Protein 2; Neoplasm Proteins; Quinolines; Structure-Activity Relationship | 2009 |
Benzanilide-Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-Type ABCG2 Modulators.
Topics: | 2013 |
Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization.
Topics: Amination; Animals; Cell Line; Flavonoids; Humans; MCF-7 Cells; Mice; Multidrug Resistance-Associated Proteins; Pyrazoles; Pyrimidines | 2016 |
Hernandezine, a Bisbenzylisoquinoline Alkaloid with Selective Inhibitory Activity against Multidrug-Resistance-Linked ATP-Binding Cassette Drug Transporter ABCB1.
Topics: Adenosine Triphosphate; Alkaloids; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzylisoquinolines; Drug Resistance, Neoplasm; Humans; Molecular Structure | 2016 |
Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators.
Topics: | 2018 |
Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Computer Simulation; Copper; Dimerization; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavones; Flavonoids; HEK293 Cells; Humans; Mice; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Triazoles | 2019 |
Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP).
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Dose-Response Relationship, Drug; Humans; KB Cells; MCF-7 Cells; Molecular Structure; Neoplasm Proteins; Quinolines; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2020 |