Page last updated: 2024-09-04

tariquidar and triptolide

tariquidar has been researched along with triptolide in 2 studies

Compound Research Comparison

Studies (tariquidar)	Trials (tariquidar)	Recent Studies (post-2010) (tariquidar)	Studies (triptolide)	Trials (triptolide)	Recent Studies (post-2010) (triptolide)
210	16	138	1,158	6	820

Protein Interaction Comparison

Protein	Taxonomy	tariquidar (IC50)	triptolide (IC50)
Prostaglandin G/H synthase 2	Homo sapiens (human)		0.04
Proteinase-activated receptor 2	Homo sapiens (human)		0.0185

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Li, H; Lu, C; Shen, GL; Tan, Y; Xiao, WB; Zhuang, XM	1
Kong, LL; Li, H; Xu, L; Yang, HY; Yuan, M; Zhuang, XM	1

Other Studies

2 other study(ies) available for tariquidar and triptolide

Article	Year
Assessment of the roles of P-glycoprotein and cytochrome P450 in triptolide-induced liver toxicity in sandwich-cultured rat hepatocyte model. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:12 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; bcl-2-Associated X Protein; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diterpenes; Epoxy Compounds; Hepatocytes; Hydrogen Peroxide; Liver; Male; Phenanthrenes; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Quercetin; Quinolines; Rats; Rats, Sprague-Dawley; Ritonavir	2013
Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. Scientific reports, 2015, Jul-02, Volume: 5 Topics: Alanine Transaminase; Animals; Apoptosis Regulatory Proteins; Aspartate Aminotransferases; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Digoxin; Diterpenes; Epoxy Compounds; Gene Knockdown Techniques; Immunologic Factors; Male; Mice, Inbred BALB C; Molecular Docking Simulation; Oxidative Stress; Phenanthrenes; Protein Binding; Quinolines; RNA, Small Interfering	2015

Article

Year

Assessment of the roles of P-glycoprotein and cytochrome P450 in triptolide-induced liver toxicity in sandwich-cultured rat hepatocyte model.

Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:12

Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; bcl-2-Associated X Protein; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diterpenes; Epoxy Compounds; Hepatocytes; Hydrogen Peroxide; Liver; Male; Phenanthrenes; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Quercetin; Quinolines; Rats; Rats, Sprague-Dawley; Ritonavir

2013

Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice.

Scientific reports, 2015, Jul-02, Volume: 5

Topics: Alanine Transaminase; Animals; Apoptosis Regulatory Proteins; Aspartate Aminotransferases; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Digoxin; Diterpenes; Epoxy Compounds; Gene Knockdown Techniques; Immunologic Factors; Male; Mice, Inbred BALB C; Molecular Docking Simulation; Oxidative Stress; Phenanthrenes; Protein Binding; Quinolines; RNA, Small Interfering

2015