tariquidar has been researched along with quinidine in 5 studies
| Studies (tariquidar) | Trials (tariquidar) | Recent Studies (post-2010) (tariquidar) | Studies (quinidine) | Trials (quinidine) | Recent Studies (post-2010) (quinidine) |
|---|---|---|---|---|---|
| 210 | 16 | 138 | 6,608 | 387 | 594 |
| Protein | Taxonomy | tariquidar (IC50) | quinidine (IC50) |
|---|---|---|---|
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | 6.4 | |
| Cholinesterase | Homo sapiens (human) | 1.23 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 10 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 3.32 | |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | 2.8 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.3532 | |
| Potassium voltage-gated channel subfamily A member 5 | Homo sapiens (human) | 7.3 | |
| Cholinesterase | Equus caballus (horse) | 7.37 | |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | 6.4 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.7882 | |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | 6.4 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 6.4 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 6.9 | |
| Potassium voltage-gated channel subfamily D member 2 | Rattus norvegicus (Norway rat) | 2.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| de Lange, EC; Schenke, M; Syvänen, S; van den Berg, DJ; Voskuyl, RA | 1 |
| Li, H; Shen, GL; Sun, HX; Yuan, M; Zhuang, XM | 1 |
| Danhof, M; de Lange, EC; Smeets, J; Westerhout, J | 1 |
| de Lange, EC; Eriksson, J; Koepp, M; Labots, M; Lammertsma, AA; Potschka, H; Rongen, M; Russmann, V; Schuit, R; Seeger, N; Syvänen, S; van Kooij, R; Verbeek, J; Voskuyl, RA; Windhorst, AD; Zellinger, C | 1 |
1 review(s) available for tariquidar and quinidine
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
4 other study(ies) available for tariquidar and quinidine
| Article | Year |
|---|---|
Alteration in P-glycoprotein functionality affects intrabrain distribution of quinidine more than brain entry-a study in rats subjected to status epilepticus by kainate.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Dose-Response Relationship, Drug; Kainic Acid; Male; Microdialysis; Nonlinear Dynamics; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Status Epilepticus; Tissue Distribution | 2012 |
[Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclosporine; Hepatocytes; Loperamide; Male; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Rhodamine 123; Tandem Mass Spectrometry | 2012 |
The impact of P-gp functionality on non-steady state relationships between CSF and brain extracellular fluid.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Extracellular Fluid; Male; Microdialysis; Models, Neurological; Quinidine; Quinolines; Rats; Rats, Wistar; Substrate Specificity; Tissue Distribution | 2013 |
[11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: impact of epilepsy and drug-responsiveness.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzazepines; Carbon Radioisotopes; Chronic Disease; Disease Models, Animal; Epilepsy; Female; Gene Expression Regulation; Kinetics; Male; Phenobarbital; Positron-Emission Tomography; Quinidine; Quinolines; Radiochemistry; Rats; Rats, Sprague-Dawley; Recurrence; Treatment Outcome | 2013 |