tariquidar has been researched along with nicardipine in 4 studies
| Studies (tariquidar) | Trials (tariquidar) | Recent Studies (post-2010) (tariquidar) | Studies (nicardipine) | Trials (nicardipine) | Recent Studies (post-2010) (nicardipine) |
|---|---|---|---|---|---|
| 210 | 16 | 138 | 2,646 | 444 | 312 |
| Protein | Taxonomy | tariquidar (IC50) | nicardipine (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 8.314 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 8 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 4.2992 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.42 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 1.69 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 2.5 | |
| Cytochrome P450 2J2 | Homo sapiens (human) | 1.69 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 4.925 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 4.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, H; Pick, A; Wiese, M | 1 |
| Berridge, G; Callaghan, R; Charlton, P; Higgins, CF; Martin, C; Mistry, P | 1 |
| Callaghan, R; Heyward, C; Modok, S | 1 |
| Callaghan, R; Kerr, ID; McMahon, R; Rothnie, A; Storm, J; Taylor, A | 1 |
4 other study(ies) available for tariquidar and nicardipine
| Article | Year |
|---|---|
Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2).
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Models, Molecular; Molecular Structure; Neoplasm Proteins; Phthalic Acids; Quantitative Structure-Activity Relationship; Quinolines; Reproducibility of Results; Stereoisomerism; Time Factors; Tumor Cells, Cultured | 2008 |
Communication between multiple drug binding sites on P-glycoprotein.
Topics: Acridines; Allosteric Regulation; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzylidene Compounds; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Drug Interactions; Isoquinolines; Kinetics; Nicardipine; Paclitaxel; Quinolines; Radioligand Assay; Radiopharmaceuticals; Rhodamine 123; Tetrahydroisoquinolines; Tritium; Vinblastine | 2000 |
P-glycoprotein retains function when reconstituted into a sphingolipid- and cholesterol-rich environment.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CHO Cells; Cholesterol; Cricetinae; Kinetics; Liposomes; Membrane Microdomains; Models, Biological; Nicardipine; Phosphatidylcholines; Quinolines; Sphingolipids; Vanadates | 2004 |
The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Baculoviridae; Binding Sites; Catalysis; Cell Line; Cell Membrane; Coumarins; Cysteine; Hydrolysis; Insecta; Kinetics; Linear Models; Mutagenesis, Site-Directed; Nicardipine; Paclitaxel; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Quinolines; Recombinant Proteins; Sulfhydryl Compounds; Time Factors; Vinblastine | 2005 |