Compounds > tariquidar
Page last updated: 2024-09-04

tariquidar and mitoxantrone

tariquidar has been researched along with mitoxantrone in 3 studies

Compound Research Comparison

Studies
(tariquidar)		Trials
(tariquidar)		Recent Studies (post-2010)
(tariquidar)		Studies
(mitoxantrone)		Trials
(mitoxantrone)		Recent Studies (post-2010) (mitoxantrone)
210161384,5551,0421,004

Protein Interaction Comparison

ProteinTaxonomytariquidar (IC50)mitoxantrone (IC50)
Chain A, Probable serine/threonine-protein kinase pknBMycobacterium tuberculosis H37Rv0.8
nonstructural protein 1Influenza A virus (A/California/07/2009(H1N1))2.049
rac GTPase-activating protein 1 isoform aHomo sapiens (human)14.46
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)3.5619
Epidermal growth factor receptorHomo sapiens (human)5.3859
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)2.0352
Tyrosine-protein kinase FynHomo sapiens (human)1.2579
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)4.9898
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.219
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.6441
ATP-dependent translocase ABCB1Homo sapiens (human)1.501
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)2.9987
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.7487
DNA topoisomerase 2-alphaHomo sapiens (human)5.3
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)1.7853
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)3.5849
Casein kinase II subunit alpha'Homo sapiens (human)0.66
Sodium-dependent noradrenaline transporter Homo sapiens (human)4.9898
5-hydroxytryptamine receptor 2CHomo sapiens (human)3.5619
Multidrug resistance-associated protein 1 Homo sapiens (human)0.0081
Casein kinase II subunit betaHomo sapiens (human)0.66
Casein kinase II subunit alphaHomo sapiens (human)0.66
Tyrosine-protein kinase BTKHomo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.5849
TAR DNA-binding protein 43Homo sapiens (human)10
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)3.5849
Integrase Human immunodeficiency virus 15.9
Multidrug and toxin extrusion protein 2Homo sapiens (human)0.68
Casein kinase II subunit alpha 3Homo sapiens (human)0.66
Multidrug and toxin extrusion protein 1Homo sapiens (human)0.3733
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)3.39
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.9038

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Chan, KF; Chan, TH; Chong, TC; Chow, LMC; Cui, J; Hu, X; Law, MC; Wong, ILK; Zhu, X1
Hanl, M; Marighetti, F; Steggemann, K; Wiese, M1

Reviews

1 review(s) available for tariquidar and mitoxantrone

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010

Other Studies

2 other study(ies) available for tariquidar and mitoxantrone

ArticleYear
Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.
    Journal of medicinal chemistry, 2019, 09-26, Volume: 62, Issue:18

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Computer Simulation; Copper; Dimerization; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavones; Flavonoids; HEK293 Cells; Humans; Mice; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Triazoles

2019
Synthesis and quantitative structure-activity relationships of selective BCRP inhibitors.
    ChemMedChem, 2013, Volume: 8, Issue:1

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Mitoxantrone; Neoplasm Proteins; Quantitative Structure-Activity Relationship; Quinolines

2013