tariquidar has been researched along with ko 143 in 10 studies
| Studies (tariquidar) | Trials (tariquidar) | Recent Studies (post-2010) (tariquidar) | Studies (ko 143) | Trials (ko 143) | Recent Studies (post-2010) (ko 143) |
|---|---|---|---|---|---|
| 210 | 16 | 138 | 51 | 0 | 42 |
| Protein | Taxonomy | tariquidar (IC50) | ko 143 (IC50) |
|---|---|---|---|
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 0.271 | |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | 4.325 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 0.1882 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, H; Pick, A; Wiese, M | 2 |
| Bernhardt, G; Buschauer, A; Egger, M; Fricker, G; König, B; Kühnle, M; Mahringer, A; Müller, C | 1 |
| Bönisch, H; Haenisch, B; Mayer, R; Müller, CE; Müller, H; Pajeva, IK; Pick, A; Weigt, M; Wiese, M | 1 |
| Bauer, S; Bernhardt, G; Buschauer, A; König, B; Kühnle, M; Ochoa-Puentes, C | 1 |
| Gallus, J; Krapf, MK; Vahdati, S; Wiese, M | 1 |
| Chan, KF; Chan, TH; Chong, TC; Chow, LMC; Cui, J; Hu, X; Law, MC; Wong, ILK; Zhu, X | 1 |
| Antoni, F; Bauer, S; Bause, M; Bernhardt, G; Buschauer, A; Jackson, SM; König, B; Locher, KP; Manolaridis, I; Scholler, M; Stark, SA | 1 |
| Chang, YT; Huang, YH; Hung, TH; Li, YQ; Wu, CP; Wu, YS | 1 |
| Cai, Z; Ghaleb, H; Huang, W; Jiang, Y; Liu, Y; Qian, H; Qiu, Q; Shi, W; Yin, Z; Zhang, P; Zhou, J; Zou, F | 1 |
10 other study(ies) available for tariquidar and ko 143
| Article | Year |
|---|---|
Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2).
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Models, Molecular; Molecular Structure; Neoplasm Proteins; Phthalic Acids; Quantitative Structure-Activity Relationship; Quinolines; Reproducibility of Results; Stereoisomerism; Time Factors; Tumor Cells, Cultured | 2008 |
Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Female; Humans; Inhibitory Concentration 50; Multidrug Resistance-Associated Protein 2; Neoplasm Proteins; Quinolines; Structure-Activity Relationship | 2009 |
Novel lead for potent inhibitors of breast cancer resistance protein (BCRP).
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzamides; Benzimidazoles; Cell Line, Tumor; Chlorophyll; Humans; Molecular Conformation; Neoplasm Proteins; Phenylurea Compounds; Small Molecule Libraries | 2010 |
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Flavonoids; Humans; Hydrogen Bonding; Models, Molecular; Neoplasm Proteins; Quantitative Structure-Activity Relationship | 2011 |
Benzanilide-Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-Type ABCG2 Modulators.
Topics: | 2013 |
New Inhibitors of Breast Cancer Resistance Protein (ABCG2) Containing a 2,4-Disubstituted Pyridopyrimidine Scaffold.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Mice; Molecular Structure; Neoplasm Proteins; Pyridines; Pyrimidines; Structure-Activity Relationship | 2018 |
Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Computer Simulation; Copper; Dimerization; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavones; Flavonoids; HEK293 Cells; Humans; Mice; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Triazoles | 2019 |
Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP).
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Dose-Response Relationship, Drug; Humans; KB Cells; MCF-7 Cells; Molecular Structure; Neoplasm Proteins; Quinolines; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2020 |
Sophoraflavanone G Resensitizes ABCG2-Overexpressing Multidrug-Resistant Non-Small-Cell Lung Cancer Cells to Chemotherapeutic Drugs.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavanones; Humans; Molecular Docking Simulation; Neoplasm Proteins | 2021 |
Exploration of novel phthalazinone derivatives as potential efflux transporter inhibitors for reversing multidrug resistance and improving the oral absorption of paclitaxel.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel | 2022 |