Compounds > tariquidar
Page last updated: 2024-09-04

tariquidar and digoxin

tariquidar has been researched along with digoxin in 3 studies

Compound Research Comparison

Studies
(tariquidar)		Trials
(tariquidar)		Recent Studies (post-2010)
(tariquidar)		Studies
(digoxin)		Trials
(digoxin)		Recent Studies (post-2010) (digoxin)
2101613811,4839581,289

Protein Interaction Comparison

ProteinTaxonomytariquidar (IC50)digoxin (IC50)
STAT3, partialHomo sapiens (human)1.862
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)0.32
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)0.0055
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.19
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-1Canis lupus familiaris (dog)0.5
Nuclear receptor ROR-gammaHomo sapiens (human)3.4798
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0055
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.2359

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Baum, L; Chanteux, H; Kwan, P; Zhang, C; Zuo, Z1
Kong, LL; Li, H; Xu, L; Yang, HY; Yuan, M; Zhuang, XM1

Reviews

1 review(s) available for tariquidar and digoxin

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010

Other Studies

2 other study(ies) available for tariquidar and digoxin

ArticleYear
Potential role for human P-glycoprotein in the transport of lacosamide.
    Epilepsia, 2013, Volume: 54, Issue:7

    Topics: Acetamides; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; Lacosamide; Quinolines; Rhodamine 123; RNA, Messenger; Swine; Time Factors; Transfection; Tritium; Verapamil

2013
Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice.
    Scientific reports, 2015, Jul-02, Volume: 5

    Topics: Alanine Transaminase; Animals; Apoptosis Regulatory Proteins; Aspartate Aminotransferases; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Digoxin; Diterpenes; Epoxy Compounds; Gene Knockdown Techniques; Immunologic Factors; Male; Mice, Inbred BALB C; Molecular Docking Simulation; Oxidative Stress; Phenanthrenes; Protein Binding; Quinolines; RNA, Small Interfering

2015