Page last updated: 2024-09-04

tariquidar and diazepam

tariquidar has been researched along with diazepam in 3 studies

Compound Research Comparison

Studies
(tariquidar)
Trials
(tariquidar)
Recent Studies (post-2010)
(tariquidar)
Studies
(diazepam)
Trials
(diazepam)
Recent Studies (post-2010) (diazepam)
2101613818,3772,3291,790

Protein Interaction Comparison

ProteinTaxonomytariquidar (IC50)diazepam (IC50)
Gamma-aminobutyric acid receptor subunit piHomo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit deltaHomo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit alpha-1Bos taurus (cattle)0.0266
Gamma-aminobutyric acid receptor subunit beta-1Bos taurus (cattle)0.0266
Gamma-aminobutyric acid receptor subunit alpha-2Bos taurus (cattle)0.0266
Gamma-aminobutyric acid receptor subunit alpha-3Bos taurus (cattle)0.0266
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit beta-1Homo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)0.0124
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0108
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0227
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit alpha-4Bos taurus (cattle)0.0266
Gamma-aminobutyric acid receptor subunit gamma-2Bos taurus (cattle)0.0266
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0106
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)0.0124
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit alpha-5Homo sapiens (human)0.0124
Gamma-aminobutyric acid receptor subunit alpha-3Homo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit alpha-2Homo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit alpha-4Homo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit epsilonHomo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit alpha-6Homo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit gamma-1Homo sapiens (human)0.0101
GABA theta subunitRattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit gamma-3Homo sapiens (human)0.0101
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0108
Gamma-aminobutyric acid receptor subunit thetaHomo sapiens (human)0.0101

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cucullo, L; Hossain, M; Janigro, D; Manders, T; Marchi, N; Rapp, E1
Bankstahl, JP; Löscher, W1
Cornelissen, AS; Hesseling, P; Joosen, MJA; Klaassen, SD; Lucassen, PJ; Meerhoff, GF; Vester, SM1

Other Studies

3 other study(ies) available for tariquidar and diazepam

ArticleYear
Development of a humanized in vitro blood-brain barrier model to screen for brain penetration of antiepileptic drugs.
    Epilepsia, 2007, Volume: 48, Issue:3

    Topics: Anticonvulsants; Astrocytes; Blood-Brain Barrier; Brain; Cells, Cultured; Coculture Techniques; Diazepam; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Electric Impedance; Endothelial Cells; Endothelium, Vascular; Epilepsy; Humans; Models, Neurological; Permeability; Phenytoin; Quinolines; Shear Strength; Sucrose; Tritium

2007
Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus.
    Epilepsy research, 2008, Volume: 82, Issue:1

    Topics: Amygdala; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Diazepam; Disease Models, Animal; Drug Resistance; Electric Stimulation; Endothelium, Vascular; Female; Gene Expression Regulation; Genes, MDR; Hippocampus; Phenobarbital; Phenytoin; Pilocarpine; Quinolines; Rats; Rats, Sprague-Dawley; Status Epilepticus

2008
Potentiation of antiseizure and neuroprotective efficacy of standard nerve agent treatment by addition of tariquidar.
    Neurotoxicology, 2018, Volume: 68

    Topics: Animals; Anticonvulsants; Astrocytes; Atropine; Brain; Cholinesterase Reactivators; Cholinesterases; Diazepam; Male; Microglia; Neurons; Neuroprotective Agents; Oximes; Pyridinium Compounds; Quinolines; Rats, Wistar; Seizures; Soman

2018