tariquidar has been researched along with cyclosporine in 17 studies
| Studies (tariquidar) | Trials (tariquidar) | Recent Studies (post-2010) (tariquidar) | Studies (cyclosporine) | Trials (cyclosporine) | Recent Studies (post-2010) (cyclosporine) |
|---|---|---|---|---|---|
| 210 | 16 | 138 | 377 | 2 | 170 |
| 210 | 16 | 138 | 30,547 | 3,802 | 6,558 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Ashworth, P; Brumwell, J; Charlton, P; Chima, L; Dangerfield, W; Folkes, A; Hunjan, S; Pretswell, I; Roe, M; Ryder, H | 1 |
| Baltes, S; Fedrowitz, M; Gastens, AM; Kaever, V; Löscher, W; Potschka, H | 1 |
| Globisch, C; Müller, H; Pajeva, IK; Wiese, M | 1 |
| Müller, H; Pick, A; Wiese, M | 1 |
| Globisch, C; Klinkhammer, W; Müller, H; Pajeva, IK; Wiese, M | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Chiba, P; Ecker, GF; Jabeen, I; Pleban, K; Rinner, U | 1 |
| Chan, KF; Chan, TH; Chong, TC; Chow, LMC; Cui, J; Hu, X; Law, MC; Wong, ILK; Zhu, X | 1 |
| Cutler, M; Lau, JYN; Lee, G; Pitzonka, L; Smolinski, MP; Suh, KH; Urgaonkar, S | 1 |
| Litman, T; Skovsgaard, T; Stein, WD | 1 |
| Greenberg, RM; Kasinathan, RS; Morgan, WM | 1 |
| Li, H; Shen, GL; Sun, HX; Yuan, M; Zhuang, XM | 1 |
| Bae, SA; Chong, DJ; Easwaramoorthy, B; Farwell, MD; Ichise, M; Iida, Y | 1 |
| Ambudkar, SV; Ansbro, MR; Li, L; Shukla, S; Yuspa, SH | 1 |
| Doligalska, M; Donskow-Łysoniewska, K; Kozłowska, E; Krawczak, K | 1 |
| Breier, A; Elefantova, K; Kubickova, J; Lakatos, B; Sulova, Z | 1 |
| Ambudkar, SV; Lusvarghi, S; Raju, N; Sajid, A; Swenson, RE; Vahedi, S | 1 |
1 review(s) available for tariquidar and cyclosporine
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
16 other study(ies) available for tariquidar and cyclosporine
| Article | Year |
|---|---|
Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance, Multiple; Drug Synergism; Humans; ortho-Aminobenzoates; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein.
Topics: Analysis of Variance; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Carbamazepine; Cell Line; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression; Humans; Levetiracetam; Mice; Phenytoin; Piracetam; Transfection | 2007 |
Functional assay and structure-activity relationships of new third-generation P-glycoprotein inhibitors.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Humans; Ligands; Models, Molecular; Molecular Structure; ortho-Aminobenzoates; Quantitative Structure-Activity Relationship | 2008 |
Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2).
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Models, Molecular; Molecular Structure; Neoplasm Proteins; Phthalic Acids; Quantitative Structure-Activity Relationship; Quinolines; Reproducibility of Results; Stereoisomerism; Time Factors; Tumor Cells, Cultured | 2008 |
Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulators.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dogs; Drug Resistance, Multiple; Magnetic Resonance Spectroscopy; Models, Molecular | 2009 |
Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzophenones; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Ligands; Models, Molecular; Molecular Conformation; Propafenone; Quantitative Structure-Activity Relationship; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 2012 |
Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Computer Simulation; Copper; Dimerization; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavones; Flavonoids; HEK293 Cells; Humans; Mice; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Triazoles | 2019 |
Discovery of Encequidar, First-in-Class Intestine Specific P-glycoprotein Inhibitor.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Drug Discovery; Humans; Intestinal Mucosa; Molecular Structure; Paclitaxel; Structure-Activity Relationship; Tetrazoles | 2021 |
Pumping of drugs by P-glycoprotein: a two-step process?
Topics: Algorithms; Animals; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Calcium Channel Blockers; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cyclosporine; Daunorubicin; Fluoresceins; Humans; Immunosuppressive Agents; Kinetics; Models, Biological; Pharmaceutical Preparations; Quinolines; Verapamil; Vinblastine | 2003 |
Genetic knockdown and pharmacological inhibition of parasite multidrug resistance transporters disrupts egg production in Schistosoma mansoni.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Female; Gene Knockdown Techniques; Male; Mice; Multidrug Resistance-Associated Proteins; Ovum; Parasite Load; Quinolines; RNA Interference; Schistosoma mansoni; Verapamil | 2011 |
[Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclosporine; Hepatocytes; Loperamide; Male; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Rhodamine 123; Tandem Mass Spectrometry | 2012 |
Imaging P-glycoprotein function in rats using [(11)C]-N-desmethyl-loperamide.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Brain; Cyclosporine; Kinetics; Loperamide; Male; Positron-Emission Tomography; Quinolines; Rats; Rats, Sprague-Dawley | 2013 |
Screening compounds with a novel high-throughput ABCB1-mediated efflux assay identifies drugs with known therapeutic targets at risk for multidrug resistance interference.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cyclosporine; Drug Resistance, Multiple; High-Throughput Screening Assays; Humans; Quinolines; Reproducibility of Results; Verapamil | 2013 |
The intestinal nematode inhibits T-cell reactivity by targeting P-GP activity.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Cyclosporine; Host-Parasite Interactions; Interleukin-4; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Nematospiroides dubius; NF-kappa B; Quinolines; Strongylida Infections; T-Lymphocyte Subsets; Verapamil | 2017 |
Detection of the Mitochondrial Membrane Potential by the Cationic Dye JC-1 in L1210 Cells with Massive Overexpression of the Plasma Membrane ABCB1 Drug Transporter.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzimidazoles; Carbocyanines; Cell Line; Cyclosporine; Fluorescent Dyes; Humans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Quinolines; Verapamil | 2018 |
Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1).
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Azoles; Boron Compounds; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; HeLa Cells; Humans; Inhibitory Concentration 50; Microscopy, Fluorescence; Molecular Docking Simulation; Molecular Imaging; Molecular Probes; Neoplasms; Nitrobenzenes; Quinolines; Recombinant Proteins | 2019 |