taraxasteryl-acetate and lupeol

To investigate the chemical constituents of Ligularia xanthotricha.. Silica gel column chromatography and preparative TLC were employed for the isolation and purification. The structures were identified on the basis of spectral data (IR, EI-MS, 1H-NMR, 13C-NMR, DEPT) and chemical evidence.. Seven compounds were isolated and identified as follows: lupeol (1), lupeol palmitate (2), 3, 28-dihydroxyl-lupeol (3), betulinic acid (4), taraxasterol (5), taraxasteryl palmitat (6) and taraxasteryl acetate(7).. All the compounds were isolated from this plant for the first time.

Topics: Asteraceae; Betulinic Acid; Chromatography, Gel; Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Molecular Structure; Pentacyclic Triterpenes; Spectrometry, Mass, Electrospray Ionization; Sterols; Triterpenes

The ethyl acetate soluble part of hexane extract of Tridax procumbens yielded a new bis-bithiophene named tridbisbithiophene along with four known terpenoids: taraxasteryl acetate, beta-amyrenone, lupeol and oleanolic acid, which have never been reported so far from Tridax procumbens. The structures of all the isolated constituents were elucidated with the aid of 1D-NMR spectroscopy whereas, the structure of new constituent tridbisbithiophene was confirmed via COSY and HMBC interactions.

Topics: Asteraceae; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oleanolic Acid; Pakistan; Pentacyclic Triterpenes; Plants, Medicinal; Sterols; Thiophenes; Triterpenes