Compounds > tanshinone ii a
Page last updated: 2024-09-05

tanshinone ii a and epigallocatechin gallate

tanshinone ii a has been researched along with epigallocatechin gallate in 4 studies

Compound Research Comparison

Studies
(tanshinone ii a)		Trials
(tanshinone ii a)		Recent Studies (post-2010)
(tanshinone ii a)		Studies
(epigallocatechin gallate)		Trials
(epigallocatechin gallate)		Recent Studies (post-2010) (epigallocatechin gallate)
610415,4561733,403

Protein Interaction Comparison

ProteinTaxonomytanshinone ii a (IC50)epigallocatechin gallate (IC50)
Chain A, POLYMERASE PAInfluenza A virus1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Chain A, Polymerase PaInfluenza A virus (A/California/04/2009(H1N1))1.9
Prostaglandin E synthaseHomo sapiens (human)1.8
Telomerase reverse transcriptaseHomo sapiens (human)1.0867
NAD kinaseHomo sapiens (human)0.96
Urokinase-type plasminogen activatorHomo sapiens (human)0.091
Tissue-type plasminogen activatorHomo sapiens (human)0.091
Polymerase acidic proteinInfluenza A virus (A/Puerto Rico/8/1934(H1N1))5.86
Amyloid-beta precursor proteinHomo sapiens (human)2.7
Plasminogen activator inhibitor 1Homo sapiens (human)0.091
Urokinase-type plasminogen activatorMus musculus (house mouse)0.091
ATP-dependent translocase ABCB1Homo sapiens (human)0.1233
72 kDa type IV collagenaseHomo sapiens (human)4.3833
Hepatocyte growth factor receptorHomo sapiens (human)10
MatrilysinHomo sapiens (human)3.34
Enoyl-[acyl-carrier-protein] reductase [NADH] FabIEscherichia coli K-125
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 21.15
Apoptosis regulator Bcl-2Homo sapiens (human)0.45
Microtubule-associated protein tauHomo sapiens (human)1.8
60 kDa heat shock protein, mitochondrialHomo sapiens (human)2.3
Glucose-6-phosphate 1-dehydrogenaseSaccharomyces cerevisiae S288C0.25
Lethal factorBacillus anthracis0.097
Phosphoglycerate mutase 1Homo sapiens (human)0.49
DNA (cytosine-5)-methyltransferase 1Homo sapiens (human)0.5
Proteasome subunit beta type-5Homo sapiens (human)0.543
DNA repair protein RAD52 homologHomo sapiens (human)2.5108
Matrix metalloproteinase-14Homo sapiens (human)6.8
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6Homo sapiens (human)3.34
Squalene monooxygenase Rattus norvegicus (Norway rat)0.69
6-phosphogluconate dehydrogenase, decarboxylatingHomo sapiens (human)0.72
BH3-interacting domain death agonistHomo sapiens (human)1.0733
Beta-secretase 1Homo sapiens (human)1.1785
10 kDa heat shock protein, mitochondrialHomo sapiens (human)2.3
Bcl-2-like protein 1Homo sapiens (human)0.59
Induced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)0.92
Alpha-(1,3)-fucosyltransferase 7Homo sapiens (human)3.34
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1Homo sapiens (human)3.34
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.3055
Mitogen-activated protein kinase 14Homo sapiens (human)2.21
Bcl-2-related protein A1Homo sapiens (human)1.79
Thiosulfate sulfurtransferaseHomo sapiens (human)7.3
60 kDa chaperonin Escherichia coli0.47
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)10
Dual specificity tyrosine-phosphorylation-regulated kinase 1ARattus norvegicus (Norway rat)0.33
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.73
10 kDa chaperonin Escherichia coli0.47
3-oxoacyl-[acyl-carrier-protein] reductase Plasmodium falciparum 3D70.32
MAP kinase-activated protein kinase 5Homo sapiens (human)1
Bcl-2-like protein 2Homo sapiens (human)2.33
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)0.225
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)0.3
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)0.215
Bcl-2-like protein 10Homo sapiens (human)0.36

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Other Studies

4 other study(ies) available for tanshinone ii a and epigallocatechin gallate

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
    Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9

    Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin

2019
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023