tanshinone ii a has been researched along with cryptotanshinone in 14 studies
| Studies (tanshinone ii a) | Trials (tanshinone ii a) | Recent Studies (post-2010) (tanshinone ii a) | Studies (cryptotanshinone) | Trials (cryptotanshinone) | Recent Studies (post-2010) (cryptotanshinone) |
|---|---|---|---|---|---|
| 61 | 0 | 41 | 370 | 0 | 268 |
| Protein | Taxonomy | tanshinone ii a (IC50) | cryptotanshinone (IC50) |
|---|---|---|---|
| Chain A, RNA-directed RNA polymerase NS5 | Dengue virus 2 16681-PDK53 | 90.06 | |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | 9.02 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 0.8 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 3.722 | |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | 10 | |
| Signal transducer and activator of transcription 3 | Homo sapiens (human) | 4.6 | |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | 9.8 | |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | 1.47 | |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | 1.47 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Bastow, KF; Don, MJ; Lee, KH; Lin, YL; Nakamura, S; Sun, CM; Wang, X; Wu, TS; Yu, HJ | 1 |
| Ding, YH; Don, MJ; Lin, YL; Shen, CC; Sun, CM; Syu, WJ | 1 |
| Dat, NT; Hong, YS; Jin, X; Kim, YH; Lee, D; Lee, JH; Lee, JJ; Lee, K | 1 |
| Leung, SW; Man, RY; Wan, AK; Zhu, DY | 1 |
| Cheung, CC; Fung, KP; Lai, PB; Lee, WY; Liu, KW; Wong, J; Yeung, JH | 1 |
| Adams, M; Fronza, M; Hamburger, M; Heinzmann, B; Laufer, S; Merfort, I; Murillo, R; Ślusarczyk, S | 1 |
| Jarstfer, MB; Keppler, BR; Lee, KH; Soares, J; Wang, X | 1 |
| Jeong, HJ; Kim, DW; Kim, JH; Kim, YM; Kwon, HJ; Lee, WS; Park, JY; Park, KH; Park, SJ; Ryu, YB | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Edwards, CC; Hatfield, MJ; Hyatt, JL; Jeffries, C; Lemoff, A; Potter, PM; Tsurkan, LG; Yan, B | 1 |
| Liu, W; Loh, ML; Qu, CK; Tang, LD; Xu, G; Xu, WR; Yu, B | 1 |
| Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW | 1 |
| Chen, S; Liu, J; Ren, J; Yang, K; Yang, X; Zhao, QS | 1 |
| Hu, Y; Jadhav, P; Tan, B; Tan, H; Wang, J | 1 |
1 review(s) available for tanshinone ii a and cryptotanshinone
| Article | Year |
|---|---|
Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease.
Topics: Antiviral Agents; Coronavirus Papain-Like Proteases; COVID-19 Drug Treatment; Humans; Pandemics; Protease Inhibitors; SARS-CoV-2 | 2022 |
13 other study(ies) available for tanshinone ii a and cryptotanshinone
| Article | Year |
|---|---|
Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Furans; Humans; Pyrones; Receptor, ErbB-2; Receptors, Estrogen; Salvia miltiorrhiza | 2004 |
Nitrogen-containing compounds from Salvia miltiorrhiza.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; HeLa Cells; Heterocyclic Compounds; Humans; Molecular Structure; Nitrogen; Plants, Medicinal; Salvia miltiorrhiza; Tumor Cells, Cultured | 2005 |
Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Drug; Humans; Hypoxia-Inducible Factor 1; Korea; Plants, Medicinal; Salvia miltiorrhiza; Tumor Cells, Cultured | 2007 |
Vascular effects of different lipophilic components of "Danshen", a traditional Chinese medicine, in the isolated porcine coronary artery.
Topics: Abietanes; Animals; Coronary Vessels; Diterpenes; Drugs, Chinese Herbal; Humans; Lipids; Medicine, Chinese Traditional; Molecular Structure; Phenanthrenes; Phenanthrolines; Plant Roots; Quinones; Salvia miltiorrhiza; Sus scrofa | 2008 |
Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells.
Topics: Abietanes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Doxorubicin; Drug Resistance, Neoplasm; Humans; Models, Biological; Molecular Structure; Phenanthrenes; Plants, Medicinal; Salvia miltiorrhiza | 2010 |
In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica.
Topics: Abietanes; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cytotoxins; Drug Screening Assays, Antitumor; Humans; Lamiaceae; Phytotherapy; Plant Extracts; Plant Roots; Salvia; Structure-Activity Relationship | 2011 |
ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide.
Topics: Abietanes; Benzoquinones; Catalase; Cell Line, Tumor; Dithiothreitol; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Oxidation-Reduction; Telomerase | 2011 |
Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases.
Topics: Abietanes; Cysteine Proteinase Inhibitors; Humans; Kinetics; Protein Binding; Salvia miltiorrhiza; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Ubiquitination | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").
Topics: Abietanes; Algorithms; Camptothecin; Carboxylesterase; Clinical Trials, Phase I as Topic; Drugs, Chinese Herbal; Herb-Drug Interactions; Humans; Irinotecan; Medicine, Chinese Traditional; Molecular Structure; Phenanthrolines; Plant Roots; Salvia miltiorrhiza | 2013 |
Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11).
Topics: Animals; Catalytic Domain; Cell Line, Tumor; Computer-Aided Design; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Inhibitors; Humans; Mice; Models, Molecular; Mutation; Phenanthrenes; Protein Tyrosine Phosphatase, Non-Receptor Type 11 | 2013 |
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors | 2021 |
Discovery and biological evaluation of tanshinone derivatives as potent dual inhibitors of indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase.
Topics: Abietanes; Enzyme Inhibitors; HeLa Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Tryptophan; Tryptophan Oxygenase | 2022 |