Page last updated: 2024-09-05

tanshinone ii a and celastrol

tanshinone ii a has been researched along with celastrol in 4 studies

Compound Research Comparison

Studies
(tanshinone ii a)
Trials
(tanshinone ii a)
Recent Studies (post-2010)
(tanshinone ii a)
Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010) (celastrol)
610418851741

Protein Interaction Comparison

ProteinTaxonomytanshinone ii a (IC50)celastrol (IC50)
Telomerase reverse transcriptaseHomo sapiens (human)0.78
Ubiquitin carboxyl-terminal hydrolase 2Homo sapiens (human)6.8
Ubiquitin carboxyl-terminal hydrolase isozyme L1Homo sapiens (human)6.8
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)8.41
Ubiquitin carboxyl-terminal hydrolase isozyme L3Homo sapiens (human)6.8
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)3.45
Tyrosine-protein phosphatase non-receptor type 6Homo sapiens (human)3.1
Tyrosine-protein phosphatase non-receptor type 11Homo sapiens (human)3.5667
Hypoxia-inducible factor 1-alphaHomo sapiens (human)0.25
Regulator of G-protein signaling 17Homo sapiens (human)6.1795
Ubiquitin carboxyl-terminal hydrolase 15Homo sapiens (human)6.8
Ubiquitin carboxyl-terminal hydrolase isozyme L5Homo sapiens (human)6.8

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Other Studies

4 other study(ies) available for tanshinone ii a and celastrol

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
    Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9

    Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin

2019
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023