Compounds > tanshinone ii a
Page last updated: 2024-09-05

tanshinone ii a and beta-lapachone

tanshinone ii a has been researched along with beta-lapachone in 4 studies

Compound Research Comparison

Studies
(tanshinone ii a)		Trials
(tanshinone ii a)		Recent Studies (post-2010)
(tanshinone ii a)		Studies
(beta-lapachone)		Trials
(beta-lapachone)		Recent Studies (post-2010) (beta-lapachone)
610414412255

Protein Interaction Comparison

ProteinTaxonomytanshinone ii a (IC50)beta-lapachone (IC50)
Lysine-specific demethylase 4EHomo sapiens (human)3
Tyrosyl-DNA phosphodiesterase 2Homo sapiens (human)0.97
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.61
60 kDa heat shock protein, mitochondrialHomo sapiens (human)2.1
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)0.72
NADHomo sapiens (human)3.2
Protein kinase C alpha typeHomo sapiens (human)1.8
Nuclear factor NF-kappa-B p105 subunitHomo sapiens (human)4
Protein-glutamine gamma-glutamyltransferase 2Homo sapiens (human)1.8
Caspase-1Homo sapiens (human)1.69
M-phase inducer phosphatase 1Homo sapiens (human)1.8
Tyrosine-protein kinase JAK3Homo sapiens (human)1.8
10 kDa heat shock protein, mitochondrialHomo sapiens (human)2.1
Nuclear factor NF-kappa-B p100 subunit Homo sapiens (human)4
Transcription factor p65Homo sapiens (human)4
Receptor-type tyrosine-protein phosphatase etaHomo sapiens (human)1.8
Thiosulfate sulfurtransferaseHomo sapiens (human)0.12
Receptor protein-tyrosine kinase Homo sapiens (human)1.8
60 kDa chaperonin Escherichia coli0.945
10 kDa chaperonin Escherichia coli0.945
Mucosa-associated lymphoid tissue lymphoma translocation protein 1Homo sapiens (human)1.55

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Hu, Y; Jadhav, P; Tan, B; Tan, H; Wang, J1

Reviews

1 review(s) available for tanshinone ii a and beta-lapachone

ArticleYear
Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease.
    Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11

    Topics: Antiviral Agents; Coronavirus Papain-Like Proteases; COVID-19 Drug Treatment; Humans; Pandemics; Protease Inhibitors; SARS-CoV-2

2022

Other Studies

3 other study(ies) available for tanshinone ii a and beta-lapachone

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
    Bioorganic & medicinal chemistry letters, 2019, 05-01, Volume: 29, Issue:9

    Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin

2019
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021