Page last updated: 2024-09-02

tanshinone and salvianolic acid a

tanshinone has been researched along with salvianolic acid a in 29 studies

Compound Research Comparison

Studies
(tanshinone)
Trials
(tanshinone)
Recent Studies (post-2010)
(tanshinone)
Studies
(salvianolic acid a)
Trials
(salvianolic acid a)
Recent Studies (post-2010) (salvianolic acid a)
1,445101,0333280262

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (13.79)29.6817
2010's17 (58.62)24.3611
2020's8 (27.59)2.80

Authors

AuthorsStudies
Chou, GX; Hu, ZB; Li, YG; Liu, M; Wang, ZT; Yang, L; Zhang, F1
Chen, X; Tang, XQ; Wang, KC; Yu, BY1
Ji, HS; Yang, J; Yu, F1
Guo, ZJ; Li, H; Sun, QS; Tang, X; Zhang, Y1
Chen, SL; Li, XW; Li, Y; Luo, HM; Niu, YY; Sun, C1
Fan, G; Gao, X; Hu, L; Jiang, M; Li, X; Wang, X; Wang, Y; Zhu, Y1
Hao, GP; Li, YL; Miao, ZM; Shi, RJ; Xin, XM1
Ding, C; Jiang, Y; Wang, L; Wang, T; Wang, X; Yang, R; Zhang, H; Zhang, L; Zhou, Y1
Chen, SL; Li, CF; Luo, HM; Song, JY; Sun, C; Xu, J1
Liu, SM; Sun, XB; Yang, ZH1
Chen, J; Dong, X; Li, P; Lu, J; Song, HP; Zhou, P1
Chen, XX; Dai, JP; Li, KS; Li, WZ; Sheng, JT; Su, Y; Wang, GF; Zhu, DX1
Bergonzi, MC; Bilia, AR; Bonaccini, L; Karioti, A1
Chen, C; Deng, K; Gao, Y; Liu, D; Liu, Y; Song, W; Wang, C; Wei, T; Yang, M; Zhang, L; Zhang, Y; Zheng, X1
Deng, K; Ji, L; Liu, Y; Sun, G; Zhang, Y; Zheng, X; Zhong, Z; Zhou, J1
Dai, JD; Huang, RX; Jiang, QL; Li, YJ; Liu, LH; Mao, YW; Zhai, WW1
Ding, K; Dong, J; Jia, Y; Liang, Z; Liu, S; Ma, P; Pei, T; Ru, M1
Choi, JS; Jung, HA; Kim, JA; Paudel, P; Seong, SH; Yu, T1
Dai, J; Wang, J; Yu, J; Zhai, W1
Gao, W; Li, P; Li, XS; Liu, K; Liu, XG; Wang, HY; Wu, QW; Yang, H; Zhang, JW1
Heo, JY; Im, DS1
Cao, P; Han, J; Wang, G; Wei, X1
Chen, M; Li, H; Tan, R; Wang, Z; Zhang, J; Zhao, S; Zheng, X1
Duan, H; Li, S; Liu, J; Tang, C; Wang, Y; Ye, Y; Zhao, G; Zhu, N1
Dong, Z; Guo, C; Qiu, B; Xue, C; Yang, H1
Cao, M; Chen, W; Jiang, W; Liu, Y; Meng, X; Peng, D; Xing, S; Zhang, W1
Ding, X; Guo, M; Liu, Z; Lv, J; Shi, J; Wang, J; Wang, X; Xu, C; Zhang, K1
Chen, X; Chen, Y; Huang, ZF; Liu, YH; Qin, DY; Yi, JH1
Chen, M; Tan, R; Wang, L; Zhang, J; Zhao, S1

Reviews

2 review(s) available for tanshinone and salvianolic acid a

ArticleYear
[Salvia miltiorrhiza as medicinal model plant].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:7

    Topics: Abietanes; Alkenes; Chromosome Mapping; Ethnopharmacology; Genome, Plant; Medicine, Chinese Traditional; Plants, Medicinal; Polyphenols; Salvia miltiorrhiza; Transcriptome

2013
Effects of Salvia miltiorrhiza on CNS Neuronal Injury and Degeneration: A Plausible Complementary Role of Tanshinones and Depsides.
    Planta medica, 2015, Volume: 81, Issue:12-13

    Topics: Abietanes; Alkenes; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cyclooxygenase 2; Depsides; Humans; Medicine, Chinese Traditional; Nerve Degeneration; Nitric Oxide Synthase Type II; Polyphenols; Salvia miltiorrhiza

2015

Other Studies

27 other study(ies) available for tanshinone and salvianolic acid a

ArticleYear
Chromatographic fingerprinting analysis of Danshen root (Salvia miltiorrhiza Radix et Rhizoma) and its preparations using high performance liquid chromatography with diode array detection and electrospray mass spectrometry (HPLC-DAD-ESI/MS).
    Journal of separation science, 2007, Volume: 30, Issue:14

    Topics: Abietanes; Benzofurans; Caffeic Acids; Chromatography, High Pressure Liquid; Cinnamates; Diterpenes; Drugs, Chinese Herbal; Lactates; Molecular Structure; Phenanthrenes; Phenylpropionates; Plant Extracts; Plant Roots; Reference Standards; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization

2007
[Analysis on biomasses and contents of active components in roots of Salvia miltiorrhiza from different populations].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:23

    Topics: Abietanes; Benzofurans; Biomass; Caffeic Acids; China; Chromatography, High Pressure Liquid; Ecosystem; Lactates; Phenanthrenes; Plant Roots; Plants, Medicinal; Salvia miltiorrhiza; Spectrophotometry, Ultraviolet

2007
[Comparative research on pharmacodynamics of Danshen co-microemulsion on hemorheology in rats with hyperlipidemia].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2008, Volume: 31, Issue:4

    Topics: Abietanes; Animals; Blood Viscosity; Caffeic Acids; Cholesterol; Drug Carriers; Drug Synergism; Drugs, Chinese Herbal; Emulsions; Hyperlipidemias; Lactates; Male; Phenanthrenes; Platelet Aggregation; Random Allocation; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Triglycerides

2008
Pharmacokinetic interaction between tanshinones and polyphenolic extracts of salvia miltinorrhiza BUNGE after intravenous administration in rats.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:8

    Topics: Abietanes; Animals; Area Under Curve; Caffeic Acids; Chromatography, High Pressure Liquid; Drug Interactions; Flavonoids; Half-Life; Injections, Intravenous; Lactates; Male; Phenanthrenes; Phenols; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Salvia miltiorrhiza

2008
[Transcriptome characterization for Salvia miltiorrhiza using 454 GS FLX].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:4

    Topics: Abietanes; Alkenes; Cytochrome P-450 Enzyme System; Databases, Nucleic Acid; DNA, Plant; Expressed Sequence Tags; Gene Expression Profiling; Genes, Plant; High-Throughput Nucleotide Sequencing; Microsatellite Repeats; Plant Roots; Plants, Medicinal; Polyphenols; Salvia miltiorrhiza; Sequence Analysis, DNA; Transcriptome

2010
Differential cardioprotective effects of salvianolic acid and tanshinone on acute myocardial infarction are mediated by unique signaling pathways.
    Journal of ethnopharmacology, 2011, Jun-01, Volume: 135, Issue:3

    Topics: Abietanes; Animals; Apoptosis; Caffeic Acids; Calcium; Cardiovascular Agents; Cell Adhesion; Complement Pathway, Alternative; Disease Models, Animal; Drugs, Chinese Herbal; Estrogens; Gene Expression Regulation; Heart; Lactates; Male; Microarray Analysis; Myocardial Infarction; Oxidative Stress; Phenanthrolines; Phytotherapy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Salvia miltiorrhiza; Selective Estrogen Receptor Modulators; Signal Transduction; Systole

2011
[Study on effective constituents extracted from fibrous roots of Salvia miltiorrhiza with degrading multi-enzymes from taishan Ganoderma lucidum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:5

    Topics: Abietanes; Alkenes; Drugs, Chinese Herbal; Hydrogen-Ion Concentration; Plant Roots; Polyphenols; Reishi; Salvia miltiorrhiza; Temperature; Wood

2013
A simple and reliable method for distinguishing danshen in salvia: simultaneous quantification of six active compositions by HPLC.
    Journal of chromatographic science, 2014, Volume: 52, Issue:9

    Topics: Abietanes; Benzofurans; Caffeic Acids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lactates; Limit of Detection; Phenanthrenes; Reproducibility of Results; Salvia; Salvia miltiorrhiza

2014
[Simultaneous determination of six Salvia miltiorrhiza gradients in rat plasma and brain by LC-MS/MS].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014, Volume: 39, Issue:9

    Topics: Abietanes; Animals; Benzaldehydes; Benzofurans; Blood-Brain Barrier; Brain; Caffeic Acids; Catechols; Chromatography, Liquid; Hydroxybenzoates; Injections, Intravenous; Lactates; Phenanthrenes; Plant Preparations; Rats; Reproducibility of Results; Salvia miltiorrhiza; Tandem Mass Spectrometry

2014
Screening of direct thrombin inhibitors from Radix Salviae Miltiorrhizae by a peak fractionation approach.
    Journal of pharmaceutical and biomedical analysis, 2015, May-10, Volume: 109

    Topics: Abietanes; Alkenes; Antithrombins; Chromatography, High Pressure Liquid; Computer Simulation; Drug Evaluation, Preclinical; Models, Molecular; Plant Roots; Polyphenols; Receptors, Drug; Reproducibility of Results; Salvia miltiorrhiza

2015
Inhibition of Tanshinone IIA, salvianolic acid A and salvianolic acid B on Areca nut extract-induced oral submucous fibrosis in vitro.
    Molecules (Basel, Switzerland), 2015, Apr-15, Volume: 20, Issue:4

    Topics: Abietanes; Animals; Areca; Benzofurans; Caffeic Acids; Cell Line; Cell Survival; Collagen; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; Humans; In Vitro Techniques; Lactates; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Nuts; Oral Submucous Fibrosis; Plant Exudates; Proto-Oncogene Proteins c-akt; Signal Transduction; Smad Proteins; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta

2015
Ectopic Expression of DREB Transcription Factor, AtDREB1A, Confers Tolerance to Drought in Transgenic Salvia miltiorrhiza.
    Plant & cell physiology, 2016, Volume: 57, Issue:8

    Topics: Abietanes; Alkenes; Arabidopsis; Arabidopsis Proteins; Catalase; Cluster Analysis; Droughts; Ectopic Gene Expression; Gene Expression Regulation, Plant; Malondialdehyde; Plant Roots; Plants, Genetically Modified; Polyphenols; Salvia miltiorrhiza; Sequence Analysis, RNA; Stress, Physiological; Superoxide Dismutase; Transcription Factors; Water

2016
Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017, Volume: 254, Issue:4

    Topics: Abietanes; Alkenes; Arabidopsis Proteins; Biosynthetic Pathways; Dehydration; Gene Expression; Gene Expression Regulation, Plant; Plant Roots; Plants, Genetically Modified; Polyphenols; Salvia miltiorrhiza; Transcription Factors; Up-Regulation

2017
[Preparation and characterization of salvianolic acids-tanshinones composite powder for inhalation via co-micronized method].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, Volume: 41, Issue:4

    Topics: Abietanes; Alkenes; Chemistry, Pharmaceutical; Drugs, Chinese Herbal; Dry Powder Inhalers; Microscopy, Electron, Scanning; Particle Size; Polyphenols; Powders; Salvia miltiorrhiza; Wettability; X-Ray Diffraction

2016
SmJAZ8 acts as a core repressor regulating JA-induced biosynthesis of salvianolic acids and tanshinones in Salvia miltiorrhiza hairy roots.
    Journal of experimental botany, 2018, 03-24, Volume: 69, Issue:7

    Topics: Abietanes; Alkenes; Co-Repressor Proteins; Cyclopentanes; Oxylipins; Plant Proteins; Plant Roots; Polyphenols; Salvia

2018
Computational insights into β-site amyloid precursor protein enzyme 1 (BACE1) inhibition by tanshinones and salvianolic acids from Salvia miltiorrhiza via molecular docking simulations.
    Computational biology and chemistry, 2018, Volume: 74

    Topics: Abietanes; Alkenes; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Computational Biology; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lamiaceae; Molecular Docking Simulation; Molecular Structure; Polyphenols; Structure-Activity Relationship

2018
Preparation and Quality Evaluation of Salvianolic Acids and Tanshinones Dry Powder Inhalation.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:9

    Topics: Abietanes; Alkenes; Chemistry, Pharmaceutical; Dry Powder Inhalers; Polyphenols; Quality Control

2018
Correlation between macroscopic characteristics and tissue-specific chemical profiling of the root of Salvia miltiorrhiza.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Dec-01, Volume: 51

    Topics: Abietanes; Alkenes; Chromatography, High Pressure Liquid; Color; Drugs, Chinese Herbal; Plant Roots; Polyphenols; Salvia miltiorrhiza; Tandem Mass Spectrometry

2018
Anti-allergic effects of salvianolic acid A and tanshinone IIA from Salvia miltiorrhiza determined using in vivo and in vitro experiments.
    International immunopharmacology, 2019, Volume: 67

    Topics: Abietanes; Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Caffeic Acids; Cell Degranulation; Cell Line; Cytokines; Disease Models, Animal; Female; Humans; Hypersensitivity; Lactates; Mast Cells; Mice; Mice, Inbred BALB C; Mucins; Rats; Salvia miltiorrhiza; Th2 Cells

2019
Microbial inoculant and garbage enzyme reduced cadmium (Cd) uptake in Salvia miltiorrhiza (Bge.) under Cd stress.
    Ecotoxicology and environmental safety, 2020, Apr-01, Volume: 192

    Topics: Abietanes; Alkenes; Biodegradation, Environmental; Biomass; Cadmium; Plant Roots; Polyphenols; Rhizosphere; Salvia miltiorrhiza; Soil Microbiology; Soil Pollutants

2020
smi-miR396b targeted SmGRFs, SmHDT1, and SmMYB37/4 synergistically regulates cell growth and active ingredient accumulation in Salvia miltiorrhiza hairy roots.
    Plant cell reports, 2020, Volume: 39, Issue:10

    Topics: Abietanes; Abscisic Acid; Acetates; Alkenes; Anthocyanins; Binding Sites; Biomass; Cell Proliferation; Cyclopentanes; Droughts; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Ontology; Gene Regulatory Networks; Gibberellins; MicroRNAs; Oxylipins; Phylogeny; Plant Proteins; Plant Roots; Plants, Genetically Modified; Polyphenols; Propanols; RNA Stability; Salt Stress; Salvia miltiorrhiza; Secondary Metabolism; Terpenes; Transcription Factors; Transcription, Genetic; Transcriptome

2020
Differential distribution of characteristic constituents in root, stem and leaf tissues of Salvia miltiorrhiza using MALDI mass spectrometry imaging.
    Fitoterapia, 2020, Volume: 146

    Topics: Abietanes; Alkenes; China; Chromatography, Liquid; Phytochemicals; Plant Leaves; Plant Roots; Plant Stems; Plants, Medicinal; Polyphenols; Salvia miltiorrhiza; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2020
Comparative pharmacokinetics of seven bioactive components in normal, sham-operated, and myocardial ischemia-reperfusion injury rats after oral administration of the Salvia Miltiorrhiza-Moutan Cortex herb pair.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:3

    Topics: Abietanes; Acids, Carbocyclic; Administration, Oral; Alkenes; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Linear Models; Male; Myocardial Reperfusion Injury; Paeonia; Polyphenols; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salvia miltiorrhiza; Sensitivity and Specificity

2021
UPLC/MS-based untargeted metabolomics reveals the changes of metabolites profile of Salvia miltiorrhiza bunge during Sweating processing.
    Scientific reports, 2020, 11-11, Volume: 10, Issue:1

    Topics: Abietanes; Alkenes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Medicine, Chinese Traditional; Metabolomics; Multivariate Analysis; Plant Roots; Polyphenols; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization

2020
Inhibition of ASC enhances the protective role of salvianolic acid A in traumatic brain injury via inhibition of inflammation and recovery of mitochondrial function.
    Folia neuropathologica, 2021, Volume: 59, Issue:1

    Topics: Abietanes; Animals; Brain Injuries, Traumatic; Caffeic Acids; Calcium; CARD Signaling Adaptor Proteins; Cell Line; Cell Proliferation; Cytokines; HEK293 Cells; Humans; Inflammation; Lactates; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Reactive Oxygen Species; Signal Transduction

2021
[Study on metabolites in vivo of Dangefentong Capsules based on UHPLC-Q/Orbitrap-MS/MS].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:18

    Topics: Abietanes; Acetonitriles; Alkenes; Animals; Capsules; Chromatography, High Pressure Liquid; Dogs; Drugs, Chinese Herbal; Flavonoids; Formates; Male; Polyphenols; Pueraria; Tandem Mass Spectrometry

2022
A tracking work on how Sm4CL2 re-directed the biosynthesis of salvianolic acids and tanshinones in Salvia miltiorrhiza hairy roots.
    Plant cell reports, 2023, Volume: 42, Issue:2

    Topics: Abietanes; Diterpenes; Follow-Up Studies; Gene Expression Regulation, Plant; Plant Roots; Salvia miltiorrhiza

2023