tanshinone has been researched along with quinidine in 4 studies
| Studies (tanshinone) | Trials (tanshinone) | Recent Studies (post-2010) (tanshinone) | Studies (quinidine) | Trials (quinidine) | Recent Studies (post-2010) (quinidine) |
|---|---|---|---|---|---|
| 1,445 | 10 | 1,033 | 6,608 | 387 | 594 |
| Protein | Taxonomy | tanshinone (IC50) | quinidine (IC50) |
|---|---|---|---|
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | 6.4 | |
| Cholinesterase | Homo sapiens (human) | 1.23 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 10 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 3.32 | |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | 2.8 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.3532 | |
| Potassium voltage-gated channel subfamily A member 5 | Homo sapiens (human) | 7.3 | |
| Cholinesterase | Equus caballus (horse) | 7.37 | |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | 6.4 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.7882 | |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | 6.4 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 6.4 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 6.9 | |
| Potassium voltage-gated channel subfamily D member 2 | Rattus norvegicus (Norway rat) | 2.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Liu, PQ; Wen, JY; Yu, XY; Zhou, SF; Zhou, ZW | 1 |
| Chen, X; Li, XX; Xue, CC; Zhou, SF; Zhou, ZW | 1 |
| Cai, B; Chu, W; Li, B; Li, X; Lu, Y; Pan, Z; Qiao, G; Shan, H; Xu, C; Yang, B; Zhang, L; Zhang, Y | 1 |
| Kwan, YW; Or, PM; Wan, DC; Wang, Y; Yeung, JH; Zhou, X | 1 |
4 other study(ies) available for tanshinone and quinidine
| Article | Year |
|---|---|
Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
Topics: Abietanes; Adenosine Triphosphate; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Digoxin; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Microsomes, Liver; Multidrug Resistance-Associated Proteins; Phenanthrenes; Plant Roots; Probenecid; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Temperature; Transfection; Verapamil | 2007 |
Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier.
Topics: Abietanes; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cells, Cultured; Endothelial Cells; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; Phenanthrenes; Plant Roots; Quinidine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Verapamil | 2007 |
Tanshinone IIA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1.
Topics: Abietanes; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Down-Regulation; Drugs, Chinese Herbal; Electrocardiography; In Vitro Techniques; Male; MicroRNAs; Myocardial Infarction; Myocytes, Cardiac; Patch-Clamp Techniques; Phenanthrenes; Potassium Channels, Inwardly Rectifying; Quinidine; Rats; Rats, Wistar; Serum Response Factor | 2009 |
Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes.
Topics: Abietanes; Amino Acids; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Dextrorphan; Drugs, Chinese Herbal; Herb-Drug Interactions; Humans; Kinetics; Microsomes, Liver; Phenanthrolines; Protein Binding; Quinidine; Salvia miltiorrhiza | 2012 |