Page last updated: 2024-09-02

tanshinone and malondialdehyde

tanshinone has been researched along with malondialdehyde in 29 studies

Compound Research Comparison

Studies
(tanshinone)
Trials
(tanshinone)
Recent Studies (post-2010)
(tanshinone)
Studies
(malondialdehyde)
Trials
(malondialdehyde)
Recent Studies (post-2010) (malondialdehyde)
1,445101,03327,8491,40513,922

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.45)18.2507
2000's9 (31.03)29.6817
2010's16 (55.17)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Cao, EH; Liu, XQ; Wang, JJ; Xu, NF1
Lu, WH; Wang, NP; Yang, XF; Zeng, FD1
Li, ZY; Liu, XL; Wang, HG1
Hiroshi, K; Jiang, T; Xu, JK; Yao, XS; Zheng, JJ1
Bao, L; Chen, S; Gao, J; Huang, H; Li, R; Liu, P; Tang, F; Wang, P; Wang, T; Wu, X; Zhang, H1
Chen, J; Fu, J; Huang, H; Liu, J; Liu, P; Pi, R1
Huang, L; Shi, XM; Xiong, SD; Zhong, XY1
Fang, ZY; Lin, R; Liu, Y; Yang, GD; Yuan, BX; Zhang, H1
Dong, K; Qiao, H; Wu, L; Xu, W; Yang, J1
Cui, L; Fang, ZY; Huang, SA; Wang, Y1
Chen, WC; Mei, B; Sun, ZW; Zhang, L; Zhu, SJ1
Bai, CL; Fu, R; Tang, C; Xue, HL1
Cao, Y; Guo, J; Huang, HQ; Liu, PQ; Liu, WH; Tang, FT; Wang, LJ; Wang, TQ; Xu, SW; Zhou, XS1
He, Z; Lu, W; Pan, Z1
He, D; Ling, S; Xu, L; Zhang, X1
Chen, S; Chen, W; Huang, H; Liu, P; Tang, F; Xie, B1
Gao, Z; Li, G; Liu, Q; Meng, Q; Wang, S; Yang, Y; Zang, W; Zhang, Q; Zhao, M; Zheng, X1
Han, B; Pang, H; Peng, Z; Yu, T1
Li, SX; Luo, K; Peng, MJ; Wang, YQ; Xie, Y; Xu, F; Yan, JY1
Fei, Y; Hu, X; Liu, C; Liu, M; Ma, K; Qian, Y; Wang, Y; Wu, Y; Yang, G; Yang, W; Zha, S; Zhang, Y1
Chen, C; Deng, K; Gao, Y; Liu, D; Liu, Y; Song, W; Wang, C; Wei, T; Yang, M; Zhang, L; Zhang, Y; Zheng, X1
Ai, L; Ding, F; Han, W; Huang, Z; Li, H; Shi, R; Wang, H; Xiao, L1
Chang, TW; Chen, EL; Chen, MH; Chen, TI; Chiang, YC; Jhang, YS; Lai, SC; Lin, CY; Lin, IH; Seenan, V; Shiung, J; Tseng, YW; Tzeng, YJ1
Bi, Y; Chen, J; Chen, L; Xu, L; Zhang, Q1
de Oliveira, MR; de Souza, ICC; Fürstenau, CR1
Chen, HH; Chen, W; Ding, W; He, JM; Huang, L; Lu, TN; Wang, MQ; Wang, ZG; Yang, Q1
Chen, R; Chen, W; Huang, X; Rui, Q1
Du, J; Feng, J; Hu, K; Liu, M; Wang, L; Xu, L; Zhao, X1
Gu, H; Lin, T; Wang, XJ; Wang, XL; Zhang, XR1

Other Studies

29 other study(ies) available for tanshinone and malondialdehyde

ArticleYear
Effect of natural antioxidant tanshinone II-A on DNA damage by lipid peroxidation in liver cells.
    Free radical biology & medicine, 1996, Volume: 20, Issue:6

    Topics: Abietanes; Animals; Antioxidants; Butylated Hydroxytoluene; Cell Survival; DNA Adducts; DNA Damage; Drugs, Chinese Herbal; Guanine; Iron Chelating Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Pentetic Acid; Phenanthrenes; Plant Extracts; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Superoxide Dismutase; Vitamin E

1996
Effects of Ginkgo biloba extract and tanshinone on cytochrome P-450 isozymes and glutathione transferase in rats.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:10

    Topics: Abietanes; Animals; Antioxidants; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Ginkgo biloba; Glutathione Transferase; Isoenzymes; Kidney; Male; Malondialdehyde; Microsomes; Microsomes, Liver; Nitric Oxide; Phenanthrenes; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley

2003
Addition of tanshinone IIA to UW solution decreases skeletal muscle ischemia-reperfusion injury.
    Acta pharmacologica Sinica, 2006, Volume: 27, Issue:8

    Topics: Abietanes; Adenosine; Adenosine Triphosphatases; Allopurinol; Animals; Apoptosis; Aspartate Aminotransferases; Creatine Kinase; Dose-Response Relationship, Drug; Glutathione; Hindlimb; Insulin; Intercellular Adhesion Molecule-1; L-Lactate Dehydrogenase; Male; Malondialdehyde; Muscle, Skeletal; Organ Preservation Solutions; Phenanthrenes; Raffinose; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase

2006
[Protective effect of tanshinones against liver injury in mice loaded with restraint stress].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:7

    Topics: Abietanes; Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Drugs, Chinese Herbal; Glutathione; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Phenanthrenes; Plants, Medicinal; Protective Agents; Reactive Oxygen Species; Restraint, Physical; Salvia miltiorrhiza; Stress, Physiological

2006
Tanshinone II A attenuates atherosclerotic calcification in rat model by inhibition of oxidative stress.
    Vascular pharmacology, 2007, Volume: 46, Issue:6

    Topics: Abietanes; Animals; Antioxidants; Aorta, Thoracic; Atherosclerosis; Calcinosis; Calcium; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Induction; Ergocalciferols; Lipoproteins, LDL; Male; Malondialdehyde; Oxidative Stress; Phenanthrenes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase; Superoxides; Time Factors

2007
Tanshinone IIA protects cardiac myocytes against oxidative stress-triggered damage and apoptosis.
    European journal of pharmacology, 2007, Jul-30, Volume: 568, Issue:1-3

    Topics: Abietanes; Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotonic Agents; Cell Survival; Cells, Cultured; DNA Fragmentation; Drugs, Chinese Herbal; Hydrogen Peroxide; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Oxidative Stress; Phenanthrenes; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2007
Protective effect of tanshinone II A on lipopolysaccharide-induced lung injury in rats.
    Chinese journal of integrative medicine, 2007, Volume: 13, Issue:2

    Topics: Abietanes; Animals; Blood Coagulation; CD18 Antigens; Drugs, Chinese Herbal; Female; Lipopolysaccharides; Lung; Male; Malondialdehyde; Phenanthrenes; Rats; Rats, Sprague-Dawley

2007
Tanshinone IIA downregulates the CD40 expression and decreases MMP-2 activity on atherosclerosis induced by high fatty diet in rabbit.
    Journal of ethnopharmacology, 2008, Jan-17, Volume: 115, Issue:2

    Topics: Abietanes; Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; CD40 Antigens; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Female; Male; Malondialdehyde; Matrix Metalloproteinase 2; Phenanthrenes; Plant Roots; Rabbits; Salvia miltiorrhiza; Superoxide Dismutase

2008
Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:5

    Topics: Abietanes; Animals; Astrocytes; Brain; Brain Ischemia; Cells, Cultured; Cerebral Infarction; Drugs, Chinese Herbal; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Phenanthrenes; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2009
[Tanshinone IIA down-regulates the expression of MMP-12 and TF in RAW 264.7 cells].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:7

    Topics: Abietanes; Animals; Cell Line; Lipoproteins, LDL; Macrophages; Malondialdehyde; Matrix Metalloproteinase 12; Mice; Thromboplastin

2009
Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage.
    Neuroscience bulletin, 2010, Volume: 26, Issue:1

    Topics: Abietanes; Amino Acids; Antioxidants; Calcium; Cell Line, Tumor; Cell Survival; Cytosol; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glutathione; Humans; Indoles; L-Lactate Dehydrogenase; Malondialdehyde; Oxidative Stress; Phenanthrenes; Superoxide Dismutase; Time Factors; Xanthenes

2010
Regulation of adhesion molecules expression in TNF-α-stimulated brain microvascular endothelial cells by tanshinone IIA: involvement of NF-κB and ROS generation.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:3

    Topics: Abietanes; Animals; Brain; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Intercellular Adhesion Molecule-1; Malondialdehyde; NF-kappa B; Rats; Reactive Oxygen Species; Salvia miltiorrhiza; Signal Transduction; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2011
Tanshinone IIA attenuates atherosclerosis in ApoE(-/-) mice through down-regulation of scavenger receptor expression.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Abietanes; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta, Thoracic; Aortic Valve; Apolipoproteins E; Atherosclerosis; Biological Transport; Body Weight; CD36 Antigens; Cell Survival; Cholesterol; Down-Regulation; Humans; Lipid Metabolism; Lipoproteins, LDL; Liver; Macrophages; Male; Malondialdehyde; Mice; Phenanthrenes; PPAR gamma; RNA, Messenger; Scavenger Receptors, Class A

2011
[Neuroprotective effects of tanshinone II A on vascular dementia in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:14

    Topics: Abietanes; Animals; Dementia, Vascular; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Male; Malondialdehyde; Maze Learning; Memory; Neuroprotective Agents; Phenanthrenes; Random Allocation; Rats; Rats, Sprague-Dawley

2010
Protective effect of tanshinone IIA on rat kidneys during hypothermic preservation.
    Molecular medicine reports, 2012, Volume: 5, Issue:2

    Topics: Abietanes; Animals; Cardioplegic Solutions; Caspase 12; Immunohistochemistry; Kidney; Male; Malondialdehyde; Organ Preservation; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Superoxide Dismutase; Transcription Factor CHOP

2012
Amelioration of atherosclerosis by tanshinone IIA in hyperlipidemic rabbits through attenuation of oxidative stress.
    European journal of pharmacology, 2012, Jan-15, Volume: 674, Issue:2-3

    Topics: Abietanes; Animals; Antioxidants; Aorta, Thoracic; Atherosclerosis; Cholesterol; Disease Progression; Glutathione Peroxidase; Hyperlipidemias; Lipoproteins, LDL; Male; Malondialdehyde; Oxidative Stress; Rabbits; Superoxide Dismutase

2012
Tanshinone IIA and Baicalin inhibiting the formation of benzo[a]pyrene and benzo[a]pyrene induced cytotoxicity: correlation with scavenging free radical.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:2

    Topics: Abietanes; Animals; Benzo(a)pyrene; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cytoprotection; Dose-Response Relationship, Drug; Flavonoids; Free Radical Scavengers; Glutathione Peroxidase; Human Umbilical Vein Endothelial Cells; Humans; Hydroxyl Radical; Inhalation Exposure; L-Lactate Dehydrogenase; Malondialdehyde; Mice; Mice, Inbred ICR; Smoke; Smoking; Solid Phase Extraction; Superoxide Dismutase; Superoxides

2013
The complex regulation of tanshinone IIA in rats with hypertension-induced left ventricular hypertrophy.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Abietanes; Animals; Apelin; Apelin Receptors; Apoptosis; Blood Pressure; Collagen; Fibrosis; Heart Function Tests; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Intercellular Signaling Peptides and Proteins; Male; Malondialdehyde; Matrix Metalloproteinase 2; Myocytes, Cardiac; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Superoxide Dismutase; Systole; Tissue Inhibitor of Metalloproteinase-2; Ultrasonography; Ventricular Remodeling

2014
[Study on pharmacokinetics-pharmacodynamics correlation of yin teng gu bi kang prescription].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2014, Volume: 37, Issue:3

    Topics: Abietanes; Administration, Oral; Animals; Antioxidants; Area Under Curve; Blood Coagulation; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Male; Malondialdehyde; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley

2014
Treatment effects of tanshinone IIA against intracerebroventricular streptozotocin induced memory deficits in mice.
    Brain research, 2016, Jan-15, Volume: 1631

    Topics: Abietanes; Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Infusions, Intraventricular; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Parietal Lobe; Random Allocation; Streptozocin; Superoxide Dismutase

2016
Ectopic Expression of DREB Transcription Factor, AtDREB1A, Confers Tolerance to Drought in Transgenic Salvia miltiorrhiza.
    Plant & cell physiology, 2016, Volume: 57, Issue:8

    Topics: Abietanes; Alkenes; Arabidopsis; Arabidopsis Proteins; Catalase; Cluster Analysis; Droughts; Ectopic Gene Expression; Gene Expression Regulation, Plant; Malondialdehyde; Plant Roots; Plants, Genetically Modified; Polyphenols; Salvia miltiorrhiza; Sequence Analysis, RNA; Stress, Physiological; Superoxide Dismutase; Transcription Factors; Water

2016
Tanshinone IIA Inhibits Glutamate-Induced Oxidative Toxicity through Prevention of Mitochondrial Dysfunction and Suppression of MAPK Activation in SH-SY5Y Human Neuroblastoma Cells.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Abietanes; Adenosine Triphosphate; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Flow Cytometry; Glutamic Acid; Humans; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potential, Mitochondrial; Protein Carbonylation; Reactive Oxygen Species

2017
Antifatigue properties of tanshinone IIA in mice subjected to the forced swimming test.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Abietanes; Animals; Blood Glucose; Blood Urea Nitrogen; Disease Models, Animal; Dose-Response Relationship, Drug; Fatigue; Female; Lactic Acid; Malondialdehyde; Mice; Salvia miltiorrhiza; Superoxide Dismutase; Swimming

2017
Tanshinone IIA exerts neuroprotective effects on hippocampus-dependent cognitive impairments in diabetic rats by attenuating ER stress-induced apoptosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 104

    Topics: Abietanes; Animals; Apoptosis; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Hippocampus; Male; Malondialdehyde; Maze Learning; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Transcription Factor CHOP

2018
Tanshinone I Induces Mitochondrial Protection by a Mechanism Involving the Nrf2/GSH Axis in the Human Neuroblastoma SH-SY5Y Cells Exposed to Methylglyoxal.
    Neurotoxicity research, 2019, Volume: 36, Issue:3

    Topics: Abietanes; Cell Line, Tumor; Glutathione; Humans; Hydrogen Peroxide; Malondialdehyde; Mitochondria; Neuroblastoma; Neuroprotective Agents; NF-E2-Related Factor 2; Nitric Oxide; Pyruvaldehyde; Reactive Oxygen Species; Superoxides

2019
Tanshinone IIA ameliorates non-alcoholic fatty liver disease through targeting peroxisome proliferator-activated receptor gamma and toll-like receptor 4.
    The Journal of international medical research, 2019, Volume: 47, Issue:10

    Topics: Abietanes; Animals; Body Weight; Lipids; Liver; Male; Malondialdehyde; NF-kappa B; Non-alcoholic Fatty Liver Disease; Organ Size; Oxidation-Reduction; PPAR gamma; Rats, Sprague-Dawley; RNA, Messenger; Toll-Like Receptor 4

2019
Tanshinone IIA attenuates heart failure via inhibiting oxidative stress in myocardial infarction rats.
    Molecular medicine reports, 2021, Volume: 23, Issue:6

    Topics: Abietanes; Actins; Animals; Antioxidants; Collagen; Fibrosis; Heart Failure; Male; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardium; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta

2021
Nose-to-brain delivery of borneol modified tanshinone IIA nanoparticles in prevention of cerebral ischemia/reperfusion injury.
    Drug delivery, 2021, Volume: 28, Issue:1

    Topics: Abietanes; Adjuvants, Pharmaceutic; Administration, Intranasal; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Brain Ischemia; Camphanes; Chemistry, Pharmaceutical; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Malondialdehyde; Nanoparticles; Neuroprotective Agents; Particle Size; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Reperfusion Injury; Succinimides; Superoxide Dismutase

2021
[Preparation of salvianolic acid B, tanshinone Ⅱ_A, and glycyrrhetinic acid lipid emulsion and its protective effect against acute liver injury induced by acetaminophen].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:17

    Topics: Abietanes; Acetaminophen; Alanine Transaminase; Animals; Antipyretics; Aspartate Aminotransferases; Benzofurans; Chemical and Drug Induced Liver Injury; Depsides; Emulsions; Glycyrrhetinic Acid; Liver; Malondialdehyde; Mice

2022