Page last updated: 2024-09-02

tanshinone and irinotecan

tanshinone has been researched along with irinotecan in 2 studies

Compound Research Comparison

Studies
(tanshinone)
Trials
(tanshinone)
Recent Studies (post-2010)
(tanshinone)
Studies
(irinotecan)
Trials
(irinotecan)
Recent Studies (post-2010) (irinotecan)
1,445101,0338,0021,8853,752

Protein Interaction Comparison

ProteinTaxonomytanshinone (IC50)irinotecan (IC50)
Solute carrier family 22 member 2Homo sapiens (human)2.7
Interstitial collagenaseHomo sapiens (human)6.06
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.556
Alpha-2C adrenergic receptorHomo sapiens (human)3.171
AcetylcholinesteraseHomo sapiens (human)1.827
Multidrug and toxin extrusion protein 2Homo sapiens (human)7.9
Multidrug and toxin extrusion protein 1Homo sapiens (human)4.7667

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Edwards, CC; Hatfield, MJ; Hyatt, JL; Jeffries, C; Lemoff, A; Potter, PM; Tsurkan, LG; Yan, B1
Chan, RL; Cho, CH; Hu, T; Li, M; Lu, L; Shen, J; To, KK; Wang, L; Yeung, JH; Zhang, L1

Other Studies

2 other study(ies) available for tanshinone and irinotecan

ArticleYear
Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").
    Journal of natural products, 2013, Jan-25, Volume: 76, Issue:1

    Topics: Abietanes; Algorithms; Camptothecin; Carboxylesterase; Clinical Trials, Phase I as Topic; Drugs, Chinese Herbal; Herb-Drug Interactions; Humans; Irinotecan; Medicine, Chinese Traditional; Molecular Structure; Phenanthrolines; Plant Roots; Salvia miltiorrhiza

2013
Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Sep-25, Volume: 21, Issue:11

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Camptothecin; Digoxin; Doxorubicin; Drugs, Chinese Herbal; Furans; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Phenanthrenes; Quinones; Salvia miltiorrhiza

2014