Page last updated: 2024-09-02

tanshinone and irinotecan

tanshinone has been researched along with irinotecan in 2 studies

Compound Research Comparison

Studies (tanshinone)	Trials (tanshinone)	Recent Studies (post-2010) (tanshinone)	Studies (irinotecan)	Trials (irinotecan)	Recent Studies (post-2010) (irinotecan)
1,445	10	1,033	8,002	1,885	3,752

Protein Interaction Comparison

Protein	Taxonomy	irinotecan (IC50)
Solute carrier family 22 member 2	Homo sapiens (human)	2.7
Interstitial collagenase	Homo sapiens (human)	6.06
Muscarinic acetylcholine receptor M4	Homo sapiens (human)	1.556
Alpha-2C adrenergic receptor	Homo sapiens (human)	3.171
Acetylcholinesterase	Homo sapiens (human)	1.827
Multidrug and toxin extrusion protein 2	Homo sapiens (human)	7.9
Multidrug and toxin extrusion protein 1	Homo sapiens (human)	4.7667

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Edwards, CC; Hatfield, MJ; Hyatt, JL; Jeffries, C; Lemoff, A; Potter, PM; Tsurkan, LG; Yan, B	1
Chan, RL; Cho, CH; Hu, T; Li, M; Lu, L; Shen, J; To, KK; Wang, L; Yeung, JH; Zhang, L	1

Other Studies

2 other study(ies) available for tanshinone and irinotecan

Article	Year
Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen"). Journal of natural products, 2013, Jan-25, Volume: 76, Issue:1 Topics: Abietanes; Algorithms; Camptothecin; Carboxylesterase; Clinical Trials, Phase I as Topic; Drugs, Chinese Herbal; Herb-Drug Interactions; Humans; Irinotecan; Medicine, Chinese Traditional; Molecular Structure; Phenanthrolines; Plant Roots; Salvia miltiorrhiza	2013
Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Sep-25, Volume: 21, Issue:11 Topics: Abietanes; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Camptothecin; Digoxin; Doxorubicin; Drugs, Chinese Herbal; Furans; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Phenanthrenes; Quinones; Salvia miltiorrhiza	2014

Article

Year

Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").

Journal of natural products, 2013, Jan-25, Volume: 76, Issue:1

Topics: Abietanes; Algorithms; Camptothecin; Carboxylesterase; Clinical Trials, Phase I as Topic; Drugs, Chinese Herbal; Herb-Drug Interactions; Humans; Irinotecan; Medicine, Chinese Traditional; Molecular Structure; Phenanthrolines; Plant Roots; Salvia miltiorrhiza

2013

Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza.

Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Sep-25, Volume: 21, Issue:11

Topics: Abietanes; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Camptothecin; Digoxin; Doxorubicin; Drugs, Chinese Herbal; Furans; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Phenanthrenes; Quinones; Salvia miltiorrhiza

2014